Lelio Orci

64.4k total citations · 23 hit papers
582 papers, 52.4k citations indexed

About

Lelio Orci is a scholar working on Surgery, Molecular Biology and Cell Biology. According to data from OpenAlex, Lelio Orci has authored 582 papers receiving a total of 52.4k indexed citations (citations by other indexed papers that have themselves been cited), including 284 papers in Surgery, 280 papers in Molecular Biology and 144 papers in Cell Biology. Recurrent topics in Lelio Orci's work include Pancreatic function and diabetes (263 papers), Cellular transport and secretion (112 papers) and Diabetes and associated disorders (88 papers). Lelio Orci is often cited by papers focused on Pancreatic function and diabetes (263 papers), Cellular transport and secretion (112 papers) and Diabetes and associated disorders (88 papers). Lelio Orci collaborates with scholars based in Switzerland, United States and France. Lelio Orci's co-authors include Roberto Montesano, Mariella Ravazzola, Roger H. Unger, M Amherdt, Alain Perrelet, Randy Schekman, Michael S. Pepper, James E. Rothman, J D Vassalli and Phillip Görden and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Lelio Orci

576 papers receiving 49.3k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Lipotoxic heart disease in obese rats: Implications for human obesity

2000 1.0k citations Lelio Orci, Roger H. Unger et al. Proceedings of the National Academy of Sciences profile →
Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor

1991 1.0k citations Roberto Montesano, Lelio Orci et al. Cell profile →
Ultrastructural localization of intracellular antigens by the use of protein A-gold complex.

1978 851 citations Lelio Orci et al. profile →
Coat Proteins and Vesicle Budding

1996 793 citations Randy Schekman, Lelio Orci profile →
Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic

1991 756 citations M Amherdt, Lelio Orci et al. Cell profile →
BI-DIRECTIONAL PROTEIN TRANSPORT BETWEEN THE ER AND GOLGI

2004 732 citations Lee M, Lelio Orci et al. profile →
Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro

1992 710 citations Michael S. Pepper, Lelio Orci et al. profile →
Basic fibroblast growth factor induces angiogenesis in vitro.

1986 679 citations Roberto Montesano, J D Vassalli et al. Proceedings of the National Academy of Sciences profile →
Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing.

1986 580 citations Mariella Ravazzola, Lelio Orci et al. profile →
The Vitamin D Endocrine System: Steroid Metabolism, Hormone Receptors, and Biological Response (Calcium Binding Proteins)*

1982 552 citations Lelio Orci et al. profile →
COPII-Coated Vesicle Formation Reconstituted with Purified Coat Proteins and Chemically Defined Liposomes

1998 523 citations Lelio Orci, M Amherdt et al. Cell profile →
In vitro rapid organization of endothelial cells into capillary-like networks is promoted by collagen matrices.

1983 523 citations Roberto Montesano, Lelio Orci et al. The Journal of Cell Biology profile →
ADP-Ribosylation factor is a subunit of the coat of Golgi-derived COP-coated vesicles: A novel role for a GTP-binding protein

1991 519 citations Lelio Orci, M Amherdt et al. Cell profile →
Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells

1991 516 citations Michael S. Pepper, Lelio Orci et al. profile →
Transforming growth factor beta stimulates collagen-matrix contraction by fibroblasts: implications for wound healing.

1988 478 citations Roberto Montesano, Lelio Orci Proceedings of the National Academy of Sciences profile →
THE ESSENTIAL ROLE OF GLUCAGON IN THE PATHOGENESIS OF DIABETES MELLITUS

1975 461 citations Lelio Orci et al. profile →
Multiple Cargo Binding Sites on the COPII Subunit Sec24p Ensure Capture of Diverse Membrane Proteins into Transport Vesicles

2003 411 citations Lee M, Susan Hamamoto et al. Cell profile →
Studies of the Diabetogenic Action of Streptozotocin.

1967 408 citations Lelio Orci et al. profile →
Sar1p N-Terminal Helix Initiates Membrane Curvature and Completes the Fission of a COPII Vesicle

2005 395 citations Lee M, Lelio Orci et al. Cell profile →
New Perspectives on the Microvasculature of the Islets of Langerhans in the Rat

1982 381 citations Lelio Orci et al. profile →
Bidirectional Transport by Distinct Populations of COPI-Coated Vesicles

1997 361 citations Lelio Orci, Mariella Ravazzola et al. Cell profile →
A coat subunit of Golgi-derived non-clathrin-coated vesicles with homology to the clathrin-coated vesicle coat protein β-adaptin

1991 338 citations Lelio Orci, James E. Rothman et al. profile →
Epidermal growth factor: morphological demonstration of binding, internalization, and lysosomal association in human fibroblasts.

1978 294 citations Lelio Orci et al. Proceedings of the National Academy of Sciences profile →

Peers

Countries citing papers authored by Lelio Orci

Since Specialization

Citations

This map shows the geographic impact of Lelio Orci's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lelio Orci with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lelio Orci more than expected).

Fields of papers citing papers by Lelio Orci

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lelio Orci. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lelio Orci. The network helps show where Lelio Orci may publish in the future.

Co-authorship network of co-authors of Lelio Orci

This figure shows the co-authorship network connecting the top 25 collaborators of Lelio Orci. A scholar is included among the top collaborators of Lelio Orci based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Lelio Orci. Lelio Orci is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Fat storage in adipocytes requires inactivation of leptin's paracrine activity: Implications for treatment of human obesity 2005 ·Proceedings of the National Academy of Sciences ·May-Yun Wang, Lelio Orci, Mariella Ravazzola, Roger H. Unger	114
2	Sar1p N-Terminal Helix Initiates Membrane Curvature and Completes the Fission of a COPII Vesicle breakdown → 2005 ·Cell ·Lee M, Lelio Orci, Susan Hamamoto, Eugene Futai, Mariella Ravazzola, Randy Schekman	395
3	Countercurrent Distribution of Two Distinct SNARE Complexes Mediating Transport within the Golgi Stack 2004 ·Molecular Biology of the Cell ·Allen Volchuk, Mariella Ravazzola, Alain Perrelet, William Eng, Maurizio Di Liberto, Oleg Varlamov, Masayoshi Fukasawa, Thomas Engel, Thomas Söllner, James E. Rothman, Lelio Orci	80
4	i-SNAREs 2003 ·The Journal of Cell Biology ·Oleg Varlamov, Allen Volchuk, (unknown), Claudia A. Doege, Fabienne Paumet, William Eng, (unknown), Francesco Parlati, Mariella Ravazzola, Lelio Orci, Thomas H. Söllner, James E. Rothman	66
5	Megavesicles Implicated in the Rapid Transport of Intracisternal Aggregates across the Golgi Stack 2000 ·Cell ·Allen Volchuk, M Amherdt, Mariella Ravazzola, Britta Brügger, Victor M. Rivera, Tim Clackson, Alain Perrelet, Thomas Söllner, James E. Rothman, Lelio Orci	93
6	Induction of epithelial branching tubulogenesis in vitro 1997 ·Journal of Cellular Physiology ·Roberto Montesano, Jesús V. Soriano, Michael S. Pepper, Lelio Orci	25
7	Coat Proteins and Selective Protein Packaging into Transport Vesicles 1995 ·Cold Spring Harbor Symposia on Quantitative Biology ·Randy Schekman, Charles Barlowe, (unknown), (unknown), Tamara L. Doering, Rainer Duden, Meta Kuehn, Michael Rexach, Tony Yeung, Lelio Orci	11
8	Modulation of bovine microvascular endothelial cell proteolytic properties by inhibitors of angiogenesis 1994 ·Journal of Cellular Biochemistry ·Michael S. Pepper, J D Vassalli, Lelio Orci, Roberto Montesano, John W. Wilks, Lothar Schweigerer	71
9	In vivo modulation of connexin 43 gene expression and junctional coupling of pancreatic B-cells 1991 ·Experimental Cell Research ·(unknown), Marc Chanson, Michael S. Pepper, Emanuele� Giordano, Domenico Bosco, Otto Traub, Klaus Willecke, A. El Aoumari, Daniel Gros, Eric C. Beyer, Lelio Orci, David C. Spray	65
10	Processing of prosomatostatin 1990 ·Metabolism ·Robert Benoit, Frederick Esch, H.P.J. Bennett, Nicholas Ling, Mariella Ravazzola, Lelio Orci, Elliott J. Mufson	23
11	Reduced beta-cell glucose transporter in new onset diabetic BB rats. 1990 ·Journal of Clinical Investigation ·Lelio Orci, Roger H. Unger, Mariella Ravazzola, Atsushi Ogawa, Ichiro Komiya, D. Baetens, Harvey F. Lodish, Bernard Thorens	83
12	Glucagon : physiology, pathophysiology, and morphology of the pancreatic A-cells 1981 ·Elsevier eBooks ·Roger H. Unger, Lelio Orci	32
13	Membrane infrastructure in Urinary Tubules 1981 ·International review of cytology ·Lelio Orci, Fabienne Humbert, Dennis Brown, Alain Perrelet	58
14	Protein A-gold complex for postembedding staining of intracellular antigens. 1980 ·PubMed ·J Roth, (unknown), Lelio Orci	3
15	Islet cell population in ob/ob and db/db mice. Abstr. 1976 ·The Mouseion at the JAXlibrary (Jackson Laboratory) ·(unknown), David Coleman, Lelio Orci	1
16	Motion analysis in pancreatic endocrine cells: saltatory movements of secretory granules along oriented pathways 1976 ·Diabetologia ·Guido Somers, Benigna Blondel, Willy Malaisse, Lelio Orci	1
17	Morphological changes in tight junctions of Necturus maculosus proximal tubules undergoing saline diuresis. 1976 ·The Journal of Cell Biology ·Frédéric Humbert, A Grandchamp, C Pricam, Alain Perrelet, Lelio Orci	65
18	Evidence for topographic partition of secretory function in the exocrine pancreas 1975 ·Digestion ·Willy Malaisse, (unknown), Patrick Robberecht, André Vandermeers, Mariella Ravazzola, Lelio Orci	3
19	Cell motility and insulin release in monolayer cultures of endocrine pancreas 1974 ·Diabetologia ·Lelio Orci, Benigna Blondel, (unknown), Mariella Ravazzola, Claes B. Wollheim, Willy Malaisse, Albert E. Renold	5
20	Participation of the microfilamentous cell web in the initial secretory response of the beta cell 1973 ·Diabetologia ·(unknown), Guido Somers, Ghislain Devis, (unknown), (unknown), Lelio Orci, Willy Malaisse	1

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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