Robert E. Hammer

67.2k total citations · 38 hit papers
290 papers, 52.9k citations indexed

About

Robert E. Hammer is a scholar working on Molecular Biology, Genetics and Surgery. According to data from OpenAlex, Robert E. Hammer has authored 290 papers receiving a total of 52.9k indexed citations (citations by other indexed papers that have themselves been cited), including 159 papers in Molecular Biology, 110 papers in Genetics and 57 papers in Surgery. Recurrent topics in Robert E. Hammer's work include Animal Genetics and Reproduction (78 papers), CRISPR and Genetic Engineering (49 papers) and Virus-based gene therapy research (31 papers). Robert E. Hammer is often cited by papers focused on Animal Genetics and Reproduction (78 papers), CRISPR and Genetic Engineering (49 papers) and Virus-based gene therapy research (31 papers). Robert E. Hammer collaborates with scholars based in United States, Germany and Japan. Robert E. Hammer's co-authors include James A. Richardson, Ralph L. Brinster, Jay D. Horton, Masashi Yanagisawa, Joseph L. Goldstein, Thomas C. Südhof, Iichiro Shimomura, Richard D. Palmiter, S. Clay Williams and Joachim Herz and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Robert E. Hammer

288 papers receiving 51.5k citations

Hit Papers

Narcolepsy in orexin Knockout Mice 1982 2026 1996 2011 1999 1993 2007 2008 1998 500 1000 1.5k 2.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Narcolepsy in orexin Knockout Mice
    1999 2.3k citations Christopher M. Sinton, James A. Richardson et al. profile →
  2. Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery.
    1993 1.3k citations Robert E. Hammer et al. Journal of Clinical Investigation profile →
  3. Endocrine Regulation of the Fasting Response by PPARα-Mediated Induction of Fibroblast Growth Factor 21
    2007 1.3k citations Laurent Gautron, Robert E. Hammer et al. Cell Metabolism profile →
  4. Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41
    2008 1.2k citations Robert E. Hammer, S. Clay Williams et al. Proceedings of the National Academy of Sciences profile →
  5. Cholesterol and Bile Acid Metabolism Are Impaired in Mice Lacking the Nuclear Oxysterol Receptor LXRα
    1998 1.2k citations Robert E. Hammer, David J. Mangelsdorf et al. profile →
  6. Synaptotagmin I: A major Ca2+ sensor for transmitter release at a central synapse
    1994 1.2k citations Robert E. Hammer, Thomas C. Südhof et al. profile →
  7. Reeler/Disabled-like Disruption of Neuronal Migration in Knockout Mice Lacking the VLDL Receptor and ApoE Receptor 2
    1999 1.1k citations Robert E. Hammer, James A. Richardson et al. profile →
  8. Tie2-Cre Transgenic Mice: A New Model for Endothelial Cell-Lineage Analysis in Vivo
    2001 1.0k citations Yaz Y. Kisanuki, Robert E. Hammer et al. Developmental Biology profile →
  9. Synaptic Assembly of the Brain in the Absence of Neurotransmitter Secretion
    2000 1.0k citations Matthijs Verhage, Robert E. Hammer et al. Science profile →
  10. Dramatic growth of mice that develop from eggs microinjected with metallothionein–growth hormone fusion genes
    1982 925 citations Richard D. Palmiter, Ralph L. Brinster et al. profile →
  11. The germfree state prevents development of gut and joint inflammatory disease in HLA-B27 transgenic rats.
    1994 887 citations James A. Richardson, Robert E. Hammer et al. profile →
  12. White Fat Progenitor Cells Reside in the Adipose Vasculature
    2008 866 citations Wei Tang, Daniel Zeve et al. Science profile →
  13. Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy
    1999 814 citations Robert E. Hammer et al. profile →
  14. Targeted and natural (piebald-lethal) mutations of endothelin-B receptor gene produce megacolon associated with spotted coat color in mice
    1994 794 citations Robert E. Hammer, James A. Richardson et al. profile →
  15. Spontaneous inflammatory disease in transgenic rats expressing HLA-B27 and human β2m: An animal model of HLA-B27-associated human disorders
    1990 785 citations Robert E. Hammer, James A. Richardson et al. profile →
  16. A Neuroligin-3 Mutation Implicated in Autism Increases Inhibitory Synaptic Transmission in Mice
    2007 759 citations Katsuhiko Tabuchi, Jacqueline Blundell et al. Science profile →
  17. Interaction of endothelin-3 with endothelin-B receptor is essential for development of epidermal melanocytes and enteric neurons
    1994 735 citations James A. Richardson, Noriaki Emoto et al. profile →
  18. Production of transgenic rabbits, sheep and pigs by microinjection
    1985 728 citations Robert E. Hammer, V. G. Pursel et al. profile →
  19. Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells.
    1997 714 citations Jay D. Horton, Robert E. Hammer et al. Journal of Clinical Investigation profile →
  20. Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a.
    1996 705 citations Jay D. Horton, Robert E. Hammer et al. Journal of Clinical Investigation profile →
  21. Decreased IRS-2 and Increased SREBP-1c Lead to Mixed Insulin Resistance and Sensitivity in Livers of Lipodystrophic and ob/ob Mice
    2000 659 citations Robert E. Hammer et al. profile →
  22. Normal luminal bacteria, especially Bacteroides species, mediate chronic colitis, gastritis, and arthritis in HLA-B27/human beta2 microglobulin transgenic rats.
    1996 652 citations Robert E. Hammer et al. Journal of Clinical Investigation profile →
  23. Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy
    1998 643 citations Robert E. Hammer, James A. Richardson et al. profile →
  24. Essential functions of synapsins I and II in synaptic vesicle regulation
    1995 617 citations Robert E. Hammer, Thomas C. Südhof et al. profile →
  25. Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2.
    1998 596 citations Jay D. Horton, Robert E. Hammer et al. Journal of Clinical Investigation profile →
  26. Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion
    2002 582 citations Robert E. Hammer, Helen H. Hobbs et al. Proceedings of the National Academy of Sciences profile →
  27. Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9
    2005 571 citations Shirya Rashid, Norma N. Anderson et al. Proceedings of the National Academy of Sciences profile →
  28. Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol
    2002 555 citations Robert E. Hammer, Jay D. Horton et al. Journal of Clinical Investigation profile →
  29. Diminished Hepatic Response to Fasting/Refeeding and Liver X Receptor Agonists in Mice with Selective Deficiency of Sterol Regulatory Element-binding Protein-1c
    2002 555 citations Guosheng Liang, Jay D. Horton et al. profile →
  30. Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and inlivers of parabiotic mice
    2006 548 citations Norma N. Anderson, Robert E. Hammer et al. Journal of Clinical Investigation profile →
  31. Acetate Dependence of Tumors
    2014 539 citations Jay D. Horton, Robert E. Hammer et al. profile →
  32. Metallothionein-Human GH Fusion Genes Stimulate Growth of Mice
    1983 537 citations Richard D. Palmiter, Robert E. Hammer et al. Science profile →
  33. α-Neurexins couple Ca2+ channels to synaptic vesicle exocytosis
    2003 527 citations Robert E. Hammer, Thomas C. Südhof et al. profile →
  34. The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development
    1998 518 citations Robert E. Hammer, David W. Russell et al. profile →
  35. Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol
    2002 511 citations Robert E. Hammer, Jay D. Horton et al. Journal of Clinical Investigation profile →
  36. Cranial and cardiac neural crest defects in endothelin-A receptor-deficient mice
    1998 507 citations David E. Clouthier, S. Clay Williams et al. profile →
  37. The role of Rab3A in neurotransmitter release
    1994 402 citations Robert E. Hammer, Thomas C. Südhof et al. profile →
  38. Double-knockout mice for α- and β-synucleins: Effect on synaptic functions
    2004 335 citations Robert E. Hammer, Thomas C. Südhof et al. Proceedings of the National Academy of Sciences profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Robert E. Hammer United States 116 27.2k 12.0k 10.7k 7.3k 6.6k 290 52.9k
Marc Montminy United States 95 26.6k 1.0× 6.9k 0.6× 6.7k 0.6× 5.1k 0.7× 3.1k 0.5× 162 39.9k
James A. Richardson United States 121 35.9k 1.3× 7.6k 0.6× 6.2k 0.6× 5.9k 0.8× 5.1k 0.8× 363 57.6k
Lelio Orci Switzerland 121 28.7k 1.1× 16.1k 1.3× 6.7k 0.6× 7.1k 1.0× 16.2k 2.5× 582 52.4k
Graeme I. Bell United States 101 19.9k 0.7× 14.2k 1.2× 11.6k 1.1× 3.9k 0.5× 3.1k 0.5× 389 36.9k
Richard D. Palmiter United States 143 30.6k 1.1× 4.4k 0.4× 13.7k 1.3× 8.6k 1.2× 3.3k 0.5× 471 69.2k
Joachim Herz United States 95 15.9k 0.6× 6.2k 0.5× 3.7k 0.3× 6.3k 0.9× 4.8k 0.7× 284 35.7k
Jun‐ichi Miyazaki Japan 85 19.4k 0.7× 7.4k 0.6× 7.2k 0.7× 2.7k 0.4× 3.0k 0.5× 498 36.0k
Christopher K. Glass United States 149 61.4k 2.3× 8.8k 0.7× 17.9k 1.7× 10.0k 1.4× 3.4k 0.5× 375 96.6k
Nabil G. Seidah Canada 104 17.2k 0.6× 11.3k 0.9× 2.7k 0.3× 3.2k 0.4× 7.5k 1.1× 706 41.6k
Dario R. Alessi United Kingdom 124 50.6k 1.9× 6.2k 0.5× 2.8k 0.3× 6.8k 0.9× 10.1k 1.5× 313 65.6k

Countries citing papers authored by Robert E. Hammer

Since Specialization
Citations

This map shows the geographic impact of Robert E. Hammer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Robert E. Hammer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Robert E. Hammer more than expected).

Fields of papers citing papers by Robert E. Hammer

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Robert E. Hammer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Robert E. Hammer. The network helps show where Robert E. Hammer may publish in the future.

Co-authorship network of co-authors of Robert E. Hammer

This figure shows the co-authorship network connecting the top 25 collaborators of Robert E. Hammer. A scholar is included among the top collaborators of Robert E. Hammer based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Robert E. Hammer. Robert E. Hammer is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Choi, Mihwa, Marc Schneeberger, Abhijit Bugde, et al.. (2023). FGF21 counteracts alcohol intoxication by activating the noradrenergic nervous system. Cell Metabolism. 35(3). 429–437.e5. 23 indexed citations
2.
Hammer, Robert E., et al.. (2022). Malignant phyllodes tumor of the breast with axillary lymph node metastasis: case report and review of the literature. European surgery. Supplement/European surgery. 54(3). 156–162. 3 indexed citations
3.
Zhou, Xiaorong, Mahesh S. Padanad, Bret M. Evers, et al.. (2018). Modulation of Mutant KrasG12D -Driven Lung Tumorigenesis In Vivo by Gain or Loss of PCDH7 Function. Molecular Cancer Research. 17(2). 594–603. 23 indexed citations
4.
Christie, Alana, Tiffani McKenzie, Nicholas C. Wolff, et al.. (2017). Modeling Renal Cell Carcinoma in Mice: Bap1 and Pbrm1 Inactivation Drive Tumor Grade. Cancer Discovery. 7(8). 900–917. 110 indexed citations
5.
Rong, Shunxing, Vı́ctor Cortés, Shirya Rashid, et al.. (2017). Expression of SREBP-1c Requires SREBP-2-mediated Generation of a Sterol Ligand for LXR in Livers of Mice. eLife. 6. 107 indexed citations
6.
Kisanuki, Yaz Y., Noriaki Emoto, Takashi Ohuchi, et al.. (2010). Low Blood Pressure in Endothelial Cell–Specific Endothelin 1 Knockout Mice. Hypertension. 56(1). 121–128. 79 indexed citations
7.
Wang, Jian, Peter B. Alexander, Leeju C. Wu, et al.. (2009). Dependence of Mouse Embryonic Stem Cells on Threonine Catabolism. Science. 325(5939). 435–439. 292 indexed citations
8.
Hao, Jing, Miwako Yamamoto, Timothy E. Richardson, et al.. (2008). Sohlh2 Knockout Mice Are Male-Sterile Because of Degeneration of Differentiating Type A Spermatogonia. Stem Cells. 26(6). 1587–1597. 80 indexed citations
9.
Tang, Wei, Daniel Zeve, Jae Myoung Suh, et al.. (2008). White Fat Progenitor Cells Reside in the Adipose Vasculature. Science. 322(5901). 583–586. 866 indexed citations breakdown →
10.
Gerber, Stefan, Jong‐Cheol Rah, Sang-Won Min, et al.. (2008). Conformational Switch of Syntaxin-1 Controls Synaptic Vesicle Fusion. Science. 321(5895). 1507–1510. 224 indexed citations
11.
Lee, Youn‐Kyoung, Daniel R. Schmidt, Carolyn L. Cummins, et al.. (2008). Liver Receptor Homolog-1 Regulates Bile Acid Homeostasis but Is Not Essential for Feedback Regulation of Bile Acid Synthesis. Molecular Endocrinology. 22(6). 1345–1356. 117 indexed citations
12.
Tabuchi, Katsuhiko, Jacqueline Blundell, Mark R. Etherton, et al.. (2007). A Neuroligin-3 Mutation Implicated in Autism Increases Inhibitory Synaptic Transmission in Mice. Science. 318(5847). 71–76. 759 indexed citations breakdown →
13.
Dann, Christina Tenenhaus, et al.. (2006). Heritable and stable gene knockdown in rats. Proceedings of the National Academy of Sciences. 103(30). 11246–11251. 59 indexed citations
14.
Yildiz, Yildiz, H. Matern, Bonne M. Thompson, et al.. (2006). Mutation of β-glucosidase 2 causes glycolipid storage disease and impaired male fertility. Journal of Clinical Investigation. 116(11). 2985–2994. 190 indexed citations
15.
Beuckmann, Carsten T., Christopher M. Sinton, S. Clay Williams, et al.. (2004). Expression of a Poly-Glutamine-Ataxin-3 Transgene in Orexin Neurons Induces Narcolepsy–Cataplexy in the Rat. Journal of Neuroscience. 24(18). 4469–4477. 137 indexed citations
16.
Ruest, L. Bruno, Hiromi Yanagisawa, Jeroen Charité, et al.. (2003). Dhand-cre transgenic mice reveal specific potential functions of dHAND during craniofacial development. Developmental Biology. 257(2). 263–277. 44 indexed citations
17.
Yanagisawa, Hiromi, Robert E. Hammer, James A. Richardson, et al.. (1998). Role of Endothelin-1/Endothelin-A receptor-mediated signaling pathway in the aortic arch patterning in mice.. Journal of Clinical Investigation. 102(1). 22–33. 153 indexed citations
18.
Linton, MacRae F., Robert V. Farese, Giulia Chiesa, et al.. (1993). Transgenic mice expressing high plasma concentrations of human apolipoprotein B100 and lipoprotein(a).. Journal of Clinical Investigation. 92(6). 3029–3037. 201 indexed citations
19.
Pursel, V. G., Caird E. Rexroad, D. J. Bolt, et al.. (1987). Progress on gene transfer in farm animals. Veterinary Immunology and Immunopathology. 17(1-4). 303–312. 65 indexed citations
20.
MacDonald, Raymond J., Robert E. Hammer, Galvin H. Swift, Brian Davis, & Ralph L. Brinster. (1986). Transgenic Progeny Inherit Tissue-Specific Expression of Rat Elastase I Genes. DNA. 5(5). 393–401. 10 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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