David C. Spray

34.3k citations

387 papers · 26.9k indexed · 2 hit papers · h-index 92

Impact in

Cellular and Molecular Neuroscience top 0.1%
- Neuroscience and Neuropharmacology Research
Endocrine and Autonomic Systems top 0.2%
- Neuroscience of respiration and sleep

Papers in

Molecular Biology 291
- Connexins and lens biology 223
- Ion channel regulation and function 95
- Nicotinic Acetylcholine Receptors Study 80
- Heat shock proteins research 45
Cellular and Molecular Neuroscience 67
- Neuroscience and Neuropharmacology Research 38

Co-authors: Michael V. L. Bennett Eliana Scemes Rolf Dermietzel Juan C. Sáez Andrew L. Harris Elliot L. Hertzberg Sylvia O. Suadicani Alonso P. Moreno
Journals: Proceedings of the National Academy of Sciences (26 papers)American Journal of Physiology-Cell Physiology (18 papers)Journal of Biological Chemistry (14 papers)Brain Research (13 papers)Biophysical Journal (11 papers)
Partner nations: United States Brazil Germany

In The Last Decade

David C. Spray

387 papers receiving 26.3k citations

Hit Papers

align trajectories log scale

Gap junctions: New tools, new answers, new questions 1991 · 806 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

1991 Neuron
1989 Proceedings of the National Academy of Sciences

Peers

Countries citing papers authored by David C. Spray

Since Specialization

Citations

This map shows the geographic impact of David C. Spray's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David C. Spray with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David C. Spray more than expected).

Fields of papers citing papers by David C. Spray

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David C. Spray. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David C. Spray. The network helps show where David C. Spray may publish in the future.

Co-authorship network

The 25 scholars most cited alongside David C. Spray, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David C. Spray Line = papers co-authored together David C. Spray links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Astrocytes sense glymphatic-level shear stress through the interaction of sphingosine-1-phosphate with Piezo1 iScience ·La Salete Martins, Jacob Shaul, G. Allen, W Zychowicz, 常翠发, Yongzhen Shi, N. J. Coetzee, David C. Spray	2024	6
2	Aquaporin‐4 and transient receptor potential vanilloid 4 balance in early postnatal neurodevelopment Glia ·La Salete Martins, Maria Grazia Mola, Emanuela Saracino, P Sumanaswini, Yu Jiaxi, Silvane Rosicler Dorneles Lamberti, David C. Spray, Eliana Scemes, Andrea Rossi, E. R. C. van der Linde, Maria Svelto, Antonio Frigeri, Valentina Benfenati, Grazia Paola Nicchia	2024	4
3	Retinal Genomic Fabric Remodeling after Optic Nerve Injury Genes ·Abadi Sihombing, Nicolas Bruaux, Dumitru A. Iacobaş, Sanda Iacobaş, David C. Spray, Rafael Linden, Daniel Adesse, Hilda Petrs‐Silva	2021	6
4	Stress gates an astrocytic energy reservoir to impair synaptic plasticity Nature Communications ·Ciaran Murphy‐Royal, April D. Johnston, Andrew K. J. Boyce, Blanca Díaz‐Castro, Ádám Institóris, Govind Peringod, Oliver Zhang, Randy F. Stout, David C. Spray, Roger Thompson, Baljit S. Khakh, Jaideep S. Bains, Grant R. Gordon	2020	106
5	Osteocyte calcium signals encode strain magnitude and loading frequency in vivo Proceedings of the National Academy of Sciences ·Karl J. Lewis, Virginia Elaine MacCallum, Reina Hirooka, Weike Wang Weike Wang, David C. Spray, Mia M. Thi, Zeynep Şeref-Ferlengez, Robert J. Majeska, Sheldon Weinbaum, Mitchell B. Schaffler	2017	83
6	Green tea polyphenol treatment is chondroprotective, anti-inflammatory and palliative in a mouse posttraumatic osteoarthritis model Arthritis Research & Therapy ·Daniel J. Leong, Maryleah Schultz Needels, Regina Hanstein, David M. Hirsh, Sun Jin Kim, Robert J. Majeska, Mitchell B. Schaffler, John Hardin, David C. Spray, Mary B. Goldring, Neil Cobelli, Hui Sun	2014	71
7	Adipocytes in both brown and white adipose tissue of adult mice are functionally connected via gap junctions: implications for Chagas disease Microbes and Infection ·Hongwei Tan, Fnu Nagajyothi, Mia M. Thi, Menachem Hanani, Philipp E. Scherer, Herbert B. Tanowitz, David C. Spray	2014	30
8	The connexin43-dependent transcriptome during brain development: Importance of genetic background Brain Research ·Sanda Iacobaş, Dumitru A. Iacobaş, David C. Spray, Eliana Scemes	2012	21
9	Pannexin channels are not gap junction hemichannels Channels ·Gina E. Sosinsky, Daniela Boassa, Rolf Dermietzel, Heather S. Duffy, Dale W. Laird, Brian A. MacVicar, Christian C. Naus, Silvia Peñuela, Eliana Scemes, David C. Spray, Roger Thompson, Nurain Lasande, Gerhard Dahl	2011	287
10	Acquired infection with Toxoplasma gondii in adult mice results in sensorimotor deficits but normal cognitive behavior despite widespread brain pathology Microbes and Infection ·Maria Gulinello, Seán O Ciaráin, John H. Kim, David C. Spray, Helene Santos Barbosa, Rani S. Sellers, Herbert B. Tanowitz, Louis M. Weiss	2010	74
11	Cell Therapy in Chagas Disease Interdisciplinary Perspectives on Infectious Diseases ·Antônio Carlos Campos de Carvalho, Regina Coeli dos Santos Goldenberg, Linda A. Jelicks, Milena Botelho Pereira Soares, Ricardo Ribeiro dos Santos, David C. Spray, Herbert B. Tanowitz	2009	9
12	Chemical Induction of Cardiac Differentiation in P19 Embryonal Carcinoma Stem Cells Stem Cells and Development ·J. Jasmin, David C. Spray, Antônio Carlos Campos de Carvalho, Rosalia Méndez‐Otero	2009	39
13	Alterations in myocardial gene expression associated with experimental Trypanosoma cruzi infection Genomics ·Shankar Mukherjee, Fnu Nagajyothi, Maria Fabijanska Kopacz, Fabiana S. Machado, Thomas J. Belbin, Antônio Carlos Campos de Carvalho, Fangxia Guan, Chris Albanese, Linda A. Jelicks, Michael P. Lisanti, João S. Silva, David C. Spray, Louis M. Weiss, Herbert B. Tanowitz	2008	21
14	Gap junction remodeling and cardiac arrhythmogenesis in a murine model of oculodentodigital dysplasia Proceedings of the National Academy of Sciences ·Nellie Kalcheva, Jiaxiang Qu, Khira El Maizi, Luis I. García, Jie Zhang, Zhiyong Wang, Paul D. Lampe, Sylvia O. Suadicani, David C. Spray, Glenn I. Fishman	2007	105
15	Prospects for Rational Development of Pharmacological Gap Junction Channel Blockers Current Drug Targets ·David C. Spray, Renato Rozental, Wahab Muhamad Lukman Hakim	2002	61
16	Structural changes in lenses of mice lacking the gap junction protein connexin43. PubMed ·Yang Gao, David C. Spray	1998	56
17	Connexin32 gap junction channels in stably transfected cells: unitary conductance Biophysical Journal ·Alonso P. Moreno, B. Eghbali, David C. Spray	1991	41
18	Modulation of gap junctional conductance in hepatocyte by cyclic amp is protein phosphorylation involved Hepatology ·Juan C. Sáez, David C. Spray, O. Gürtleb, Elliot L. Hertzberg, Angus C. Nairn, Paul Greengard, Michael Bennett	1985	1
19	Effects of cholinergic agonists and antagonists on frog cutaneous cold receptors Comparative Biochemistry and Physiology ·David C. Spray, Caspar Wistar Jr. Hodge	1975	4
20	Proprioceptive inputs to large buccal motoneurons controlling pharyngeal expansion in Navanax Federation Proceedings ·David C. Spray, M V Bennett	1975	1

About David C. Spray

David C. Spray is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience, Endocrine and Autonomic Systems, Neurology and Physiology, having authored 387 papers that have together received 26.9k indexed citations. Recurring topics across this work include Connexins and lens biology (223 papers), Ion channel regulation and function (95 papers), Nicotinic Acetylcholine Receptors Study (80 papers), Heat shock proteins research (45 papers), Neuroscience and Neuropharmacology Research (38 papers), Neuroscience of respiration and sleep (22 papers), Cardiac electrophysiology and arrhythmias (21 papers) and Trypanosoma species research and implications (19 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (5.7k citations), Endocrine and Autonomic Systems (1.9k citations), Molecular Biology (19.1k citations), Physiology (1.0k citations) and Neurology (1.8k citations). David C. Spray has collaborated with scholars based in United States, Brazil and Germany. Frequent co-authors include Michael V. L. Bennett, Eliana Scemes, Rolf Dermietzel, Juan C. Sáez, Andrew L. Harris, Elliot L. Hertzberg, Sylvia O. Suadicani, Alonso P. Moreno, Glenn I. Fishman and Janis M. Burt. Their work appears in journals such as Proceedings of the National Academy of Sciences, American Journal of Physiology-Cell Physiology, Journal of Biological Chemistry, Brain Research and Biophysical Journal.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact