Yoshimi Takai

67.7k total citations · 14 hit papers
629 papers, 57.1k citations indexed

About

Yoshimi Takai is a scholar working on Molecular Biology, Cell Biology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Yoshimi Takai has authored 629 papers receiving a total of 57.1k indexed citations (citations by other indexed papers that have themselves been cited), including 494 papers in Molecular Biology, 285 papers in Cell Biology and 79 papers in Cellular and Molecular Neuroscience. Recurrent topics in Yoshimi Takai's work include Cellular transport and secretion (153 papers), Protein Kinase Regulation and GTPase Signaling (142 papers) and Wnt/β-catenin signaling in development and cancer (134 papers). Yoshimi Takai is often cited by papers focused on Cellular transport and secretion (153 papers), Protein Kinase Regulation and GTPase Signaling (142 papers) and Wnt/β-catenin signaling in development and cancer (134 papers). Yoshimi Takai collaborates with scholars based in Japan, United States and United Kingdom. Yoshimi Takai's co-authors include Yasutomi Nishizuka, Kozo Kaibuchi, Takuya Sasaki, Ushio Kikkawa, Hiroyuki Nakanishi, Akira Kishimoto, Akira Kikuchi, Ken‐Ichi Sano, Takashi Matozaki and Marco Castagna and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Yoshimi Takai

625 papers receiving 55.5k citations

Hit Papers

Direct activation of calcium-activated, phospholipid-depe... 1977 2026 1993 2009 1982 2001 1980 1979 1982 1000 2.0k 3.0k 4.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.
    1982 4.2k citations Yoshimi Takai, Kozo Kaibuchi et al. Journal of Biological Chemistry profile →
  2. Small GTP-Binding Proteins
    2001 2.0k citations Yoshimi Takai, Takuya Sasaki et al. profile →
  3. Activation of calcium and phospholipid-dependent protein kinase by diacylglycerol, its possible relation to phosphatidylinositol turnover.
    1980 1.1k citations Yoshimi Takai et al. Journal of Biological Chemistry profile →
  4. Calcium-dependent activation of a multifunctional protein kinase by membrane phospholipids.
    1979 995 citations Yoshimi Takai et al. Journal of Biological Chemistry profile →
  5. Calcium-activated, phospholipid-dependent protein kinase from rat brain. Subcellular distribution, purification, and properties.
    1982 928 citations Yoshimi Takai et al. Journal of Biological Chemistry profile →
  6. Protein kinase C as a possible receptor protein of tumor-promoting phorbol esters.
    1983 788 citations Yoshimi Takai et al. Journal of Biological Chemistry profile →
  7. Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. II. Proenzyme and its activation by calcium-dependent protease from rat brain.
    1977 729 citations Yoshimi Takai et al. Journal of Biological Chemistry profile →
  8. Synergistic functions of protein phosphorylation and calcium mobilization in platelet activation.
    1983 623 citations Kozo Kaibuchi, Yoshimi Takai et al. Journal of Biological Chemistry profile →
  9. Unsaturated diacylglycerol as a possible messenger for the activation of calcium-activated, phospholipid-dependent protein kinase system
    1979 600 citations Yoshimi Takai et al. Biochemical and Biophysical Research Communications profile →
  10. Binding of Neuroligins to PSD-95
    1997 593 citations Yoshimi Takai et al. Science profile →
  11. Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP
    1998 574 citations Takuya Sasaki, Yoshimi Takai et al. profile →
  12. Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway.
    1996 509 citations Takuya Sasaki, Yoshimi Takai et al. The Journal of Cell Biology profile →
  13. Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. I. Purification and characterization of an active enzyme from bovine cerebellum.
    1977 501 citations Yoshimi Takai et al. Journal of Biological Chemistry profile →
  14. Inhibitory action of chlorpromazine, dibucaine, and other phospholipid-interacting drugs on calcium-activated, phospholipid-dependent protein kinase.
    1980 417 citations Yoshimi Takai et al. Journal of Biological Chemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Yoshimi Takai Japan 115 40.5k 20.2k 8.2k 5.8k 5.3k 629 57.1k
Kozo Kaibuchi Japan 123 37.8k 0.9× 19.6k 1.0× 9.6k 1.2× 3.9k 0.7× 6.4k 1.2× 510 56.0k
Shuh Narumiya Japan 125 28.8k 0.7× 12.0k 0.6× 8.3k 1.0× 7.4k 1.3× 8.6k 1.6× 556 60.6k
Yasutomi Nishizuka Japan 95 42.1k 1.0× 8.8k 0.4× 9.7k 1.2× 5.7k 1.0× 6.8k 1.3× 255 57.7k
Christer Betsholtz Sweden 100 28.8k 0.7× 6.5k 0.3× 5.3k 0.7× 4.6k 0.8× 4.4k 0.8× 327 52.3k
Dario R. Alessi United Kingdom 124 50.6k 1.2× 10.1k 0.5× 4.7k 0.6× 4.9k 0.8× 6.8k 1.3× 313 65.6k
Robert G. Parton Australia 129 35.9k 0.9× 27.9k 1.4× 2.7k 0.3× 4.3k 0.7× 10.0k 1.9× 410 54.2k
Kun‐Liang Guan United States 148 57.9k 1.4× 32.0k 1.6× 4.3k 0.5× 7.3k 1.3× 7.2k 1.4× 422 89.1k
James R. Woodgett Canada 108 35.7k 0.9× 5.8k 0.3× 5.7k 0.7× 4.8k 0.8× 4.4k 0.8× 293 47.6k
Richard G.W. Anderson United States 98 26.5k 0.7× 18.4k 0.9× 2.4k 0.3× 3.1k 0.5× 6.8k 1.3× 176 39.0k
J. Silvio Gutkind United States 121 33.7k 0.8× 7.8k 0.4× 4.9k 0.6× 6.9k 1.2× 3.3k 0.6× 582 52.2k

Countries citing papers authored by Yoshimi Takai

Since Specialization
Citations

This map shows the geographic impact of Yoshimi Takai's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Yoshimi Takai with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Yoshimi Takai more than expected).

Fields of papers citing papers by Yoshimi Takai

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Yoshimi Takai. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Yoshimi Takai. The network helps show where Yoshimi Takai may publish in the future.

Co-authorship network of co-authors of Yoshimi Takai

This figure shows the co-authorship network connecting the top 25 collaborators of Yoshimi Takai. A scholar is included among the top collaborators of Yoshimi Takai based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Yoshimi Takai. Yoshimi Takai is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Kameyama, Takeshi, et al.. (2022). Stimulatory role of nectin‐4 and p95‐ErbB2 in multilayered T47D cell proliferation. Genes to Cells. 27(6). 451–464.
2.
3.
Sugiura, Ayumu, et al.. (2019). Nectin-4 cis-interacts with ErbB2 and its trastuzumab-resistant splice variants, enhancing their activation and DNA synthesis. Scientific Reports. 9(1). 18997–18997. 29 indexed citations
4.
Mizutani, Kiyohito, et al.. (2017). Nectin-like molecule-4/cell adhesion molecule 4 inhibits the ligand-induced dimerization of ErbB3 with ErbB2. Scientific Reports. 7(1). 11375–11375. 7 indexed citations
5.
Minami, Akihiro, Yohei Shimono, Kiyohito Mizutani, et al.. (2013). Reduction of the ST6 β-Galactosamide α-2,6-Sialyltransferase 1 (ST6GAL1)-catalyzed Sialylation of Nectin-like Molecule 2/Cell Adhesion Molecule 1 and Enhancement of ErbB2/ErbB3 Signaling by MicroRNA-199a. Journal of Biological Chemistry. 288(17). 11845–11853. 34 indexed citations
6.
Minami, Akihiro, Yohei Shimono, Kiyohito Mizutani, et al.. (2013). miR‐214 and hypoxia down‐regulate Necl‐2/CADM1 and enhance ErbB2/ErbB3 signaling. Genes to Cells. 18(3). 195–202. 18 indexed citations
7.
Takai, Yoshimi, et al.. (2012). APPLICABILITY OF READABILITY FORMULAE TO THE MEASUREMENT OF SENTENCE-LEVEL READABILITY. 6023–6031. 3 indexed citations
8.
Togashi, Hideru, Masazumi Waseda, Hitomi Komura, et al.. (2011). Nectins Establish a Checkerboard-Like Cellular Pattern in the Auditory Epithelium. Science. 333(6046). 1144–1147. 97 indexed citations
9.
Groffen, Alexander J., Sascha Martens, L. Niels Cornelisse, et al.. (2010). Doc2b Is a High-Affinity Ca 2+ Sensor for Spontaneous Neurotransmitter Release. Science. 327(5973). 1614–1618. 253 indexed citations
10.
Togashi, Hideru, Jun Miyoshi, Tomoyuki Honda, et al.. (2006). Interneurite affinity is regulated by heterophilic nectin interactions in concert with the cadherin machinery. The Journal of Cell Biology. 174(1). 141–151. 88 indexed citations
11.
Sato, Tatsuhiro, Kenji Irie, Ryoko Okamoto, et al.. (2005). Common signaling pathway is used by the trans‐interaction of Necl‐5/Tage4/PVR/CD155 and nectin, and of nectin and nectin during the formation of cell–cell adhesion. Cancer Science. 96(9). 578–589. 21 indexed citations
12.
Kawagishi, Rikako, Masahiro Tahara, Kenichiro Morishige, et al.. (2005). Expression of nectin-2 in mouse granulosa cells. European Journal of Obstetrics & Gynecology and Reproductive Biology. 121(1). 71–76. 11 indexed citations
13.
Shimizu, Kazuya, Tomomi Kawakatsu, Yukiko Minami, et al.. (2004). Activation of Cdc42 by trans interactions of the cell adhesion molecules nectins through c-Src and Cdc42-GEF FRG. The Journal of Cell Biology. 166(3). 393–405. 92 indexed citations
14.
Toi, Hirofumi, Konomi Fujimura‐Kamada, Kenji Irie, et al.. (2003). She4p/Dim1p Interacts with the Motor Domain of Unconventional Myosins in the Budding Yeast,Saccharomyces cerevisiae. Molecular Biology of the Cell. 14(6). 2237–2249. 60 indexed citations
15.
Pokutta, Sabine, Frauke Drees, Yoshimi Takai, W. James Nelson, & William I. Weis. (2002). Biochemical and Structural Definition of the l-Afadin- and Actin-binding Sites of α-Catenin. Journal of Biological Chemistry. 277(21). 18868–18874. 202 indexed citations
16.
Ohtsuka, Toshihisa, Yutaka Hata, Nobuyuki Ide, et al.. (1999). nRap GEP: A Novel Neural GDP/GTP Exchange Protein for Rap1 Small G Protein That Interacts with Synaptic Scaffolding Molecule (S-SCAM). Biochemical and Biophysical Research Communications. 265(1). 38–44. 93 indexed citations
17.
Yokoyama, Shigekazu, Hiromichi Shirataki, Toshiaki Sakisaka, & Yoshimi Takai. (1999). Three Splicing Variants of Tomosyn and Identification of Their Syntaxin-Binding Region. Biochemical and Biophysical Research Communications. 256(1). 218–222. 31 indexed citations
18.
Hori, Yuichi, Yoshifumi Takeyama, Motoki Hiroyoshi, et al.. (1996). Possible involvement of Rab11 p24, a Ras-like small GTP-binding protein, in intracellular vesicular transport of isolated pancreatic acini. Digestive Diseases and Sciences. 41(1). 133–138. 11 indexed citations
19.
Takai, Yoshimi, Kozo Kaibuchi, Akira Kikuchi, & Takuya Sasaki. (1995). [11] Effects of prenyl modifications on interactions of small G proteins with regulators. Methods in enzymology on CD-ROM/Methods in enzymology. 250. 122–133. 7 indexed citations
20.
Regazzi, Romano, Takuya Sasaki, Kazuo Takahashi, et al.. (1995). Prenylcysteine analogs mimicking the C-terminus of GTP-binding proteins stimulate exocytosis from permeabilized HIT-T15 cells: comparison with the effect of Rab3AL peptide. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1268(3). 269–278. 18 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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