James E. Rothman

39.6k total citations · 24 hit papers
157 papers, 31.8k citations indexed

About

James E. Rothman is a scholar working on Cell Biology, Molecular Biology and Cellular and Molecular Neuroscience. According to data from OpenAlex, James E. Rothman has authored 157 papers receiving a total of 31.8k indexed citations (citations by other indexed papers that have themselves been cited), including 133 papers in Cell Biology, 125 papers in Molecular Biology and 16 papers in Cellular and Molecular Neuroscience. Recurrent topics in James E. Rothman's work include Cellular transport and secretion (130 papers), Lipid Membrane Structure and Behavior (85 papers) and Endoplasmic Reticulum Stress and Disease (27 papers). James E. Rothman is often cited by papers focused on Cellular transport and secretion (130 papers), Lipid Membrane Structure and Behavior (85 papers) and Endoplasmic Reticulum Stress and Disease (27 papers). James E. Rothman collaborates with scholars based in United States, France and Germany. James E. Rothman's co-authors include Thomas Söllner, Sidney W. Whiteheart, Thomas C. Südhof, Dino A. De Angelis, Gero Miesenböck, Felix Wieland, James A. McNew, Paul Tempst, Francesco Parlati and Gregory C. Flynn and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

James E. Rothman

156 papers receiving 31.3k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

SNAP receptors implicated in vesicle targeting and fusion

1993 2.6k citations Thomas Söllner, Sidney W. Whiteheart et al. Nature profile →
SNAREpins: Minimal Machinery for Membrane Fusion

1998 2.0k citations Thomas Söllner, James E. Rothman et al. Cell profile →
Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins

1998 2.0k citations James E. Rothman et al. Nature profile →
Mechanisms of intracellular protein transport

1994 1.9k citations James E. Rothman Nature profile →
A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion

1993 1.6k citations Thomas Söllner, Sidney W. Whiteheart et al. Cell profile →
Membrane Fusion: Grappling with SNARE and SM Proteins

2009 1.5k citations James E. Rothman et al. Science profile →
Protein Sorting by Transport Vesicles

1996 979 citations James E. Rothman et al. Science profile →
Peptide Binding and Release by Proteins Implicated as Catalysts of Protein Assembly

1989 654 citations James E. Rothman et al. Science profile →
Peptide-binding specificity of the molecular chaperone BiP

1991 644 citations James E. Rothman et al. Nature profile →
Inhibition by brefeldin A of a Golgi membrane enzyme that catalyses exchange of guanine nucleotide bound to ARF

1992 638 citations James E. Rothman et al. Nature profile →
Compartmental specificity of cellular membrane fusion encoded in SNARE proteins

2000 537 citations Fabienne Paumet, Thomas Söllner et al. Nature profile →
Uncoating ATPase is a member of the 70 kilodalton family of stress proteins

1986 527 citations James E. Rothman et al. Cell profile →
Implications of the SNARE hypothesis for intracellular membrane topology and dynamics

1994 480 citations James E. Rothman et al. profile →
A fusion protein required for vesicle-mediated transport in both mammalian cells and yeast

1989 474 citations James E. Rothman et al. Nature profile →
A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles

1994 452 citations James E. Rothman, Thomas Söllner et al. Cell profile →
SNAPs, a family of NSF attachment proteins involved in intracellular membrane fusion in animals and yeast

1990 447 citations James E. Rothman et al. Cell profile →
Purification of an N-ethylmaleimide-sensitive protein catalyzing vesicular transport.

1988 416 citations James E. Rothman et al. Proceedings of the National Academy of Sciences profile →
Brefeldin A, a drug that blocks secretion, prevents the assembly of non-clathrin-coated buds on Golgi cisternae

1991 409 citations James E. Rothman et al. Cell profile →
Selective Activation of Cognate SNAREpins by Sec1/Munc18 Proteins

2007 368 citations Fabienne Paumet, James E. Rothman et al. Cell profile →
An enzyme that removes clathrin coats: purification of an uncoating ATPase.

1984 364 citations James E. Rothman et al. profile →
Bidirectional Transport by Distinct Populations of COPI-Coated Vesicles

1997 361 citations Thomas Söllner, James E. Rothman et al. Cell profile →
N-ethylmaleimide-sensitive fusion protein: a trimeric ATPase whose hydrolysis of ATP is required for membrane fusion.

1994 350 citations Sidney W. Whiteheart, James E. Rothman et al. profile →
A coat subunit of Golgi-derived non-clathrin-coated vesicles with homology to the clathrin-coated vesicle coat protein β-adaptin

1991 338 citations James E. Rothman et al. Nature profile →
Single Reconstituted Neuronal SNARE Complexes Zipper in Three Distinct Stages

2012 315 citations Ying Gao, Sylvain Zorman et al. Science profile →

Peers

Countries citing papers authored by James E. Rothman

Since Specialization

Citations

This map shows the geographic impact of James E. Rothman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James E. Rothman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James E. Rothman more than expected).

Fields of papers citing papers by James E. Rothman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James E. Rothman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James E. Rothman. The network helps show where James E. Rothman may publish in the future.

Co-authorship network of co-authors of James E. Rothman

This figure shows the co-authorship network connecting the top 25 collaborators of James E. Rothman. A scholar is included among the top collaborators of James E. Rothman based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with James E. Rothman. James E. Rothman is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Quantitative single-molecule analysis of assembly and Ca2+-dependent disassembly of synaptotagmin oligomers on lipid bilayers 2024 ·Communications Biology ·Feng Li, Jeff Coleman, Lorena Redondo‐Morata, Ramalingam Venkat Kalyana Sundaram, (unknown), James E. Rothman, Frédéric Pincet	0
2	Unraveling cellular complexity with transient adapters in highly multiplexed super-resolution imaging 2024 ·Cell ·Florian Schueder, Félix Rivera-Molina, Maohan Su, Zach Marin, P. Kidd, James E. Rothman, Derek Toomre, Joerg Bewersdorf	40
3	Synaptophysin chaperones the assembly of 12 SNAREpins under each ready-release vesicle 2023 ·Proceedings of the National Academy of Sciences ·(unknown), Abhijith Radhakrishnan, Jeff Coleman, Ramalingam Venkat Kalyana Sundaram, Sathish Ramakrishnan, Frédéric Pincet, James E. Rothman	21
4	Synaptotagmin rings as high-sensitivity regulators of synaptic vesicle docking and fusion 2022 ·Proceedings of the National Academy of Sciences ·Jie Zhu, Zachary A. McDargh, Feng Li, Shyam S. Krishnakumar, James E. Rothman, Ben O’Shaughnessy	12
5	Nascent fusion pore opening monitored at single-SNAREpin resolution 2021 ·Proceedings of the National Academy of Sciences ·Paul Heo, Jeff Coleman, Jean‐Baptiste Fleury, James E. Rothman, Frédéric Pincet	17
6	A novel physiological role for ARF1 in the formation of bidirectional tubules from the Golgi 2017 ·Molecular Biology of the Cell ·Francesca Bottanelli, Nicole Kilian, Andreas M. Ernst, Félix Rivera-Molina, Lena K. Schroeder, Emil B. Kromann, Mark D. Lessard, Roman S. Erdmann, Alanna Schepartz, David Baddeley, Joerg Bewersdorf, Derek Toomre, James E. Rothman	52
7	Preparation and characterization of SNARE-containing nanodiscs and direct study of cargo release through fusion pores 2013 ·Nature Protocols ·Lei Shi, (unknown), Qing-Tao Shen, Yong‐Jian Wang, James E. Rothman, Frédéric Pincet	27
8	SNARE Proteins: One to Fuse and Three to Keep the Nascent Fusion Pore Open 2012 ·Science ·Lei Shi, Qing-Tao Shen, Alexander Kiel, Jing Wang, Hongwei Wang, Thomas J. Melia, James E. Rothman, Frédéric Pincet	204
9	Single Reconstituted Neuronal SNARE Complexes Zipper in Three Distinct Stages breakdown → 2012 ·Science ·Ying Gao, Sylvain Zorman, (unknown), Zhiqun Xi, Lu Ma, George Sirinakis, James E. Rothman, Yongli Zhang	315
10	Molecular Mechanism of Protein Folding in the Cell 2011 ·Cell ·James E. Rothman, Randy Schekman	31
11	A fast, single-vesicle fusion assay mimics physiological SNARE requirements 2010 ·Proceedings of the National Academy of Sciences ·Erdem Karatekin, (unknown), Cécile Iborra, Jeff Coleman, Ben O’Shaughnessy, Michael Seagar, James E. Rothman	117
12	A Fast, Single-Vesicle Fusion Assay Mimics Physiological SNARE Requirements 2010 ·Biophysical Journal ·Erdem Karatekin, (unknown), Cécile Iborra, Jeff Coleman, Ben O’Shaughnessy, Michael Seagar, James E. Rothman	1
13	The Future of Golgi Research 2010 ·Molecular Biology of the Cell ·James E. Rothman	23
14	Alternative Zippering as an On-Off Switch for SNARE-Mediated Fusion 2009 ·Science ·Claudio G. Giraudo, Alejandro Garcia-Diaz, William Eng, Yuhang Chen, Wayne A. Hendrickson, Thomas J. Melia, James E. Rothman	127
15	Cell‐Based Assays Using Primary Endothelial Cells to Study Multiple Steps in Inflammation 2006 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Thomas U. Mayer, Bernd Jagla, Michael R. Wyler, Peter D. Kelly, Nathalie Aulner, Matthew Beard, (unknown), (unknown), Deborah H. Smith, Lars J. Brandén, James E. Rothman	8
16	Differential use of endoplasmic reticulum membrane for phagocytosis in J774 macrophages 2005 ·Proceedings of the National Academy of Sciences ·(unknown), Allen Volchuk, James E. Rothman	96
17	Concerted Auto-regulation in Yeast Endosomal t-SNAREs 2005 ·Journal of Biological Chemistry ·Fabienne Paumet, (unknown), Maurizio Di Liberto, James E. Rothman	10
18	Localization and activity of the SNARE Ykt6 determined by its regulatory domain and palmitoylation 2004 ·Proceedings of the National Academy of Sciences ·Masayoshi Fukasawa, Oleg Varlamov, William Eng, Thomas Söllner, James E. Rothman	113
19	Fusion of Cells by Flipped SNAREs 2003 ·Science ·Chuan Hu, Mahiuddin Ahmed, Thomas J. Melia, Thomas H. Söllner, Thomas U. Mayer, James E. Rothman	181
20	SNAP-mediated protein–protein interactions essential for neurotransmitter release 1995 ·Nature ·William M. DeBello, Vincent O’Connor, Thomas Dresbach, Sidney W. Whiteheart, Samuel S.‐H. Wang, Felix E. Schweizer, Hartmut Bertz, James E. Rothman, George J. Augustine	130

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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