Nigel Mackman

54.0k total citations · 14 hit papers
508 papers, 39.6k citations indexed

About

Nigel Mackman is a scholar working on Hematology, Internal Medicine and Immunology. According to data from OpenAlex, Nigel Mackman has authored 508 papers receiving a total of 39.6k indexed citations (citations by other indexed papers that have themselves been cited), including 286 papers in Hematology, 122 papers in Internal Medicine and 107 papers in Immunology. Recurrent topics in Nigel Mackman's work include Blood Coagulation and Thrombosis Mechanisms (253 papers), Venous Thromboembolism Diagnosis and Management (122 papers) and Platelet Disorders and Treatments (60 papers). Nigel Mackman is often cited by papers focused on Blood Coagulation and Thrombosis Mechanisms (253 papers), Venous Thromboembolism Diagnosis and Management (122 papers) and Platelet Disorders and Treatments (60 papers). Nigel Mackman collaborates with scholars based in United States, Germany and United Kingdom. Nigel Mackman's co-authors include Mausumee Guha, Graham C. Parry, Rafał Pawliński, Yohei Hisada, A. Phillip Owens, Steven P. Grover, Thomas S. Edgington, Nigel S. Key, I. Barry Holland and Korbinian Brand and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Nigel Mackman

489 papers receiving 38.9k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

LPS induction of gene expression in human monocytes

2001 2.0k citations Nigel Mackman et al. profile →
HIF-1α Is Essential for Myeloid Cell-Mediated Inflammation

2003 1.6k citations Rafał Pawliński, Nigel Mackman et al. profile →
Triggers, targets and treatments for thrombosis

2008 924 citations Nigel Mackman profile →
The Phosphatidylinositol 3-Kinase-Akt Pathway Limits Lipopolysaccharide Activation of Signaling Pathways and Expression of Inflammatory Mediators in Human Monocytic Cells

2002 675 citations Nigel Mackman et al. Journal of Biological Chemistry profile →
Microparticles in Hemostasis and Thrombosis

2011 647 citations A. Phillip Owens, Nigel Mackman Circulation Research profile →
Role of tissue factor in embryonic blood vessel development

1996 541 citations Nigel Mackman et al. profile →
Role of the Extrinsic Pathway of Blood Coagulation in Hemostasis and Thrombosis

2007 529 citations Nigel Mackman et al. Arteriosclerosis Thrombosis and Vascular Biology profile →
Tissue Factor

2018 499 citations Steven P. Grover, Nigel Mackman Arteriosclerosis Thrombosis and Vascular Biology profile →
Inflammasome Activation Triggers Blood Clotting and Host Death through Pyroptosis

2019 308 citations Yohei Hisada, Steven P. Grover et al. profile →
Cancer-associated pathways and biomarkers of venous thrombosis

2017 299 citations Yohei Hisada, Nigel Mackman Blood profile →
Neutrophil Extracellular Traps

2019 292 citations Charlotte Thålin, Yohei Hisada et al. Arteriosclerosis Thrombosis and Vascular Biology profile →
Therapeutic strategies for thrombosis: new targets and approaches

2020 264 citations Nigel Mackman, Wolfgang Bergmeier et al. profile →
Cancer-associated venous thromboembolism

2022 235 citations Nigel Mackman et al. profile →
Understanding COVID-19-associated coagulopathy

2022 191 citations Nigel Mackman, Alisa S. Wolberg et al. profile →

Peers

Countries citing papers authored by Nigel Mackman

Since Specialization

Citations

This map shows the geographic impact of Nigel Mackman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nigel Mackman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nigel Mackman more than expected).

Fields of papers citing papers by Nigel Mackman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nigel Mackman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nigel Mackman. The network helps show where Nigel Mackman may publish in the future.

Co-authorship network of co-authors of Nigel Mackman

This figure shows the co-authorship network connecting the top 25 collaborators of Nigel Mackman. A scholar is included among the top collaborators of Nigel Mackman based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Nigel Mackman. Nigel Mackman is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	4D intravital imaging studies identify platelets as the predominant cellular procoagulant surface in a mouse hemostasis model 2024 ·Blood ·(unknown), Robert H. Lee, (unknown), Paul Y. Kim, (unknown), Rafał Pawliński, Matthew J. Flick, David S. Paul, Nigel Mackman, David Adalsteinsson, Wolfgang Bergmeier	7
2	Loss of P2Y1 receptor desensitization does not impact hemostasis or thrombosis despite increased platelet reactivity in vitro 2023 ·Journal of Thrombosis and Haemostasis ·David S. Paul, (unknown), (unknown), (unknown), (unknown), Nigel Mackman, (unknown), (unknown), (unknown), T. Kendall Harden, Wolfgang Bergmeier, Robert A. Nicholas	2
3	Western blot and immunohistochemical analysis of mouse tissue factor 2023 ·Research and Practice in Thrombosis and Haemostasis ·Nigel Mackman, Yohei Hisada, Jin‐Ah Park	0
4	High plasma levels of C1-inhibitor are associated with lower risk of future venous thromboembolism 2023 ·Journal of Thrombosis and Haemostasis ·Steven P. Grover, Omri Snir, Kristian Hindberg, (unknown), Sigrid K. Brækkan, Vânia M. Morelli, (unknown), Alisa S. Wolberg, Tom Eirik Mollnes, Thor Ueland, Nigel Mackman, John‐Bjarne Hansen	8
5	C1 inhibitor deficiency enhances contact pathway mediated activation of coagulation and venous thrombosis 2023 ·Blood ·Steven P. Grover, Tomohiro Kawano, Jun Wan, (unknown), (unknown), (unknown), Omri Snir, Sigrid K. Brækkan, (unknown), (unknown), (unknown), Keith R. McCrae, Alisa S. Wolberg, John‐Bjarne Hansen, Henriette Farkas, Nigel Mackman	17
6	Thrombin-mediated activation of PAR1 enhances doxorubicin-induced cardiac injury in mice 2022 ·Blood Advances ·Steven P. Grover, (unknown), Jens Posma, John H. Griffin, Joseph S. Palumbo, Nigel Mackman, Silvio Antoniak	4
7	A targetable pathway in neutrophils mitigates both arterial and venous thrombosis 2022 ·Science Translational Medicine ·Lalitha Nayak, David R. Sweet, (unknown), Stephanie Lapping, (unknown), (unknown), Vinesh Vinayachandran, Roshan Padmanabhan, (unknown), Jay Myers, Alex Y. Huang, Alvin H. Schmaier, Nigel Mackman, Xudong Liao, Andrei Maiseyeu, Mukesh K. Jain	35
8	Role of tissue factor in delayed bone repair induced by diabetic state in mice 2021 ·PLoS ONE ·(unknown), Kohei Tatsumi, Yoshimasa Takafuji, Naoyuki Kawao, Masayoshi Ishida, Kiyotaka Okada, Nigel Mackman, Hiroshi Kaji	2
9	Patients With COVID-19 Have Elevated Levels of Circulating Extracellular Vesicle Tissue Factor Activity That Is Associated With Severity and Mortality—Brief Report 2020 ·Arteriosclerosis Thrombosis and Vascular Biology ·Axel Rosell, Sebastian Havervall, Fien A. von Meijenfeldt, Yohei Hisada, Katherina Aguilera, Steven P. Grover, Ton Lisman, Nigel Mackman, Charlotte Thålin	167
10	Mitochondria Are a Subset of Extracellular Vesicles Released by Activated Monocytes and Induce Type I IFN and TNF Responses in Endothelial Cells 2019 ·Circulation Research ·Florian Puhm, Taras Afonyushkin, Ulrike Resch, Georg Obermayer, Manfred Rohde, T. Penz, Michael Schuster, Gabriel Wagner, André F. Rendeiro, Imène Melki, Christoph Kaun, Johann Wojta, Christoph Bock, Bernd Jilma, Nigel Mackman, Éric Boilard, Christoph J. Binder	201
11	mTOR kinase inhibition reduces tissue factor expression and growth of pancreatic neuroendocrine tumors 2018 ·Journal of Thrombosis and Haemostasis ·(unknown), Hala Elnakat Thomas, (unknown), (unknown), (unknown), (unknown), (unknown), Yohei Hisada, H W Davis, Xiaoyang Qi, Carol A. Mercer, Fred V. Lucas, Bruce J. Aronow, Nigel Mackman, Henri H. Versteeg, Vladimir Y. Bogdanov	11
12	Protease-activated receptor 1 activation enhances doxorubicin-induced cardiotoxicity 2018 ·Journal of Molecular and Cellular Cardiology ·Silvio Antoniak, Kohei Tatsumi, (unknown), Steven P. Grover, Rafał Pawliński, Nigel Mackman	21
13	Thrombin promotes diet-induced obesity through fibrin-driven inflammation 2017 ·Journal of Clinical Investigation ·Anna K. Kopec, (unknown), Sherry Thornton, Joseph S. Palumbo, Eric S. Mullins, Senad Divanovic, Hartmut Weiler, A. Phillip Owens, Nigel Mackman, Ashley Goss, Joanne van Ryn, James P. Luyendyk, Matthew J. Flick	92
14	Tissue factor expression provokes escape from tumor dormancy and leads to genomic alterations 2014 ·Proceedings of the National Academy of Sciences ·Nathalie Magnus, Delphine Garnier, Brian Meehan, Serge McGraw, Tae Hoon Lee, Maxime Caron, Guillaume Bourque, Chlöe Milsom, Nada Jabado, Jacquetta M. Trasler, Rafał Pawliński, Nigel Mackman, Janusz Rak	86
15	Hepatocyte tissue factor activates the coagulation cascade in mice 2013 ·Blood ·Bradley P. Sullivan, Anna K. Kopec, Nikita Joshi, (unknown), Juliette A. Brown, Stephanie Bishop, Karen M. Kassel, Cheryl E. Rockwell, Nigel Mackman, James P. Luyendyk	56
16	PAR-1 contributes to the innate immune response during viral infection 2013 ·Journal of Clinical Investigation ·Silvio Antoniak, A. Phillip Owens, (unknown), Julie Williams, (unknown), Alice Weithäuser, Patricia A. Sheridan, (unknown), James P. Luyendyk, Denise Esserman, JoAnn Trejo, Daniel Kirchhofer, Burns C. Blaxall, Rafał Pawliński, Melinda A. Beck, Ursula Rauch, Nigel Mackman	110
17	Tissue Factor–Activated Coagulation Cascade in the Tumor Microenvironment Is Critical for Tumor Progression and an Effective Target for Therapy 2011 ·Cancer Research ·Yuan Liu, Pengfei Jiang, Kateřina Čapková, Xue Dong, (unknown), Subhash C. Sinha, Nigel Mackman, Kim D. Janda, Cheng Liu	82
18	Epidermal Growth Factor Receptor and PTEN Modulate Tissue Factor Expression in Glioblastoma through JunD/Activator Protein-1 Transcriptional Activity 2009 ·Cancer Research ·Yuan Rong, Vladimir E. Belozerov, Carol Tucker‐Burden, (unknown), Donald L. Durden, Jeffrey J. Olson, Erwin G. Van Meir, Nigel Mackman, Daniel J. Brat	114
19	Endotoxemia and sepsis mortality reduction by non-anticoagulant–activated protein C 2007 ·The Journal of Experimental Medicine ·E. J. Kerschen, José A. Fernández, Brian C. Cooley, Xia V. Yang, Rashmi Sood, Laurent O. Mosnier, Francis Castellino, Nigel Mackman, John H. Griffin, Hartmut Weiler	243
20	Activation of NF-κB by Bradykinin through a Gαq- and Gβγ-dependent Pathway That Involves Phosphoinositide 3-Kinase and Akt 2000 ·Journal of Biological Chemistry ·Ping Xie, Darren D. Browning, Nissim Hay, Nigel Mackman, Richard D. Ye	124

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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