Pamela S. Ohashi

52.5k total citations · 14 hit papers
317 papers, 33.6k citations indexed

About

Pamela S. Ohashi is a scholar working on Immunology, Oncology and Molecular Biology. According to data from OpenAlex, Pamela S. Ohashi has authored 317 papers receiving a total of 33.6k indexed citations (citations by other indexed papers that have themselves been cited), including 252 papers in Immunology, 94 papers in Oncology and 52 papers in Molecular Biology. Recurrent topics in Pamela S. Ohashi's work include Immune Cell Function and Interaction (177 papers), T-cell and B-cell Immunology (149 papers) and Immunotherapy and Immune Responses (100 papers). Pamela S. Ohashi is often cited by papers focused on Immune Cell Function and Interaction (177 papers), T-cell and B-cell Immunology (149 papers) and Immunotherapy and Immune Responses (100 papers). Pamela S. Ohashi collaborates with scholars based in Canada, United States and Switzerland. Pamela S. Ohashi's co-authors include Tak W. Mak, Wen‐Chen Yeh, Andrew Wakeham, Yong‐Chen Lu, Thomas M. Kündig, Arda Shahinian, Linh T. Nguyen, Josef Penninger, Martin F. Bachmann and Bernhard Odermatt and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Pamela S. Ohashi

310 papers receiving 33.0k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

LPS/TLR4 signal transduction pathway

2008 2.6k citations Pamela S. Ohashi et al. profile →
Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

1993 1.5k citations Andrew Wakeham, Arda Shahinian et al. profile →
Differential T Cell Costimulatory Requirements in CD28-Deficient Mice

1993 1.1k citations Arda Shahinian, Andrew Wakeham et al. Science profile →
Ablation of “tolerance” and induction of diabetes by virus infection in viral antigen transgenic mice

1991 957 citations Pamela S. Ohashi et al. profile →
Function of PI3Kγ in Thymocyte Development, T Cell Activation, and Neutrophil Migration

2000 889 citations Russell G. Jones, Andrew Wakeham et al. Science profile →
Deregulated T Cell Activation and Autoimmunity in Mice Lacking Interleukin-2 Receptor β

1995 727 citations Andrew Wakeham, Pamela S. Ohashi et al. Science profile →
Early Lethality, Functional NF-κB Activation, and Increased Sensitivity to TNF-Induced Cell Death in TRAF2-Deficient Mice

1997 705 citations Wen-Chen Yeh, Arda Shahinian et al. profile →
Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4

2002 650 citations Gordon S. Duncan, Douglas G. Millar et al. profile →
Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development

1993 566 citations Andrew Wakeham, Pamela S. Ohashi et al. profile →
ICOS is essential for effective T-helper-cell responses

2001 558 citations Arda Shahinian, Andrew Wakeham et al. profile →
Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b

2000 553 citations Sanjeev Mariathasan, Andrew Wakeham et al. profile →
Clinical blockade of PD1 and LAG3 — potential mechanisms of action

2014 495 citations Linh T. Nguyen, Pamela S. Ohashi profile →
T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance

2001 463 citations Toshiaki Ohteki, Andrew Wakeham et al. profile →
The Roles of CD8+ T Cell Subsets in Antitumor Immunity

2020 393 citations Michael St. Paul, Pamela S. Ohashi profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Pamela S. Ohashi Canada	93	23.0k	10.1k	7.2k	3.8k	2.9k	317	33.6k
Howard A. Young United States	97	16.6k 0.7×	9.5k 0.9×	6.3k 0.9×	2.5k 0.7×	2.8k 1.0×	369	31.4k
George Kollias Greece	89	10.9k 0.5×	12.1k 1.2×	5.6k 0.8×	3.5k 0.9×	3.1k 1.1×	306	30.3k
Chen Dong United States	100	27.8k 1.2×	8.6k 0.9×	8.4k 1.2×	2.9k 0.8×	2.6k 0.9×	330	39.9k
John J. O’Shea United States	110	31.2k 1.4×	11.2k 1.1×	15.2k 2.1×	3.1k 0.8×	3.2k 1.1×	323	49.8k
Pascal Schneider Switzerland	85	17.4k 0.8×	14.9k 1.5×	5.1k 0.7×	4.8k 1.3×	2.4k 0.8×	261	33.5k
Hal E. Broxmeyer United States	89	12.3k 0.5×	10.1k 1.0×	9.6k 1.3×	2.2k 0.6×	2.4k 0.8×	570	30.4k
David Cosman United States	81	17.8k 0.8×	9.1k 0.9×	7.7k 1.1×	2.4k 0.6×	1.9k 0.7×	151	28.7k
Jacques J. Peschon United States	63	11.5k 0.5×	9.1k 0.9×	5.9k 0.8×	3.2k 0.8×	1.7k 0.6×	94	24.8k
Andrew Wakeham Canada	73	13.3k 0.6×	17.3k 1.7×	7.9k 1.1×	5.6k 1.5×	2.2k 0.7×	112	31.5k
Michael J. Lenardo United States	89	17.6k 0.8×	14.9k 1.5×	6.5k 0.9×	5.1k 1.3×	2.4k 0.8×	244	34.1k

Countries citing papers authored by Pamela S. Ohashi

Since Specialization

Citations

This map shows the geographic impact of Pamela S. Ohashi's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Pamela S. Ohashi with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Pamela S. Ohashi more than expected).

Fields of papers citing papers by Pamela S. Ohashi

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Pamela S. Ohashi. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Pamela S. Ohashi. The network helps show where Pamela S. Ohashi may publish in the future.

Co-authorship network of co-authors of Pamela S. Ohashi

This figure shows the co-authorship network connecting the top 25 collaborators of Pamela S. Ohashi. A scholar is included among the top collaborators of Pamela S. Ohashi based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Pamela S. Ohashi. Pamela S. Ohashi is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Chung, Douglas C., Maryam Ghaedi, Kathrin Warner, et al.. (2024). Characterization of innate lymphoid cell subsets infiltrating melanoma and epithelial ovarian tumors. OncoImmunology. 13(1). 2349347–2349347. 1 indexed citations

Murakami, Kiichi, Andrew Elia, Yukiko Shibahara, et al.. (2021). Therapeutic inhibition of USP9x-mediated Notch signaling in triple-negative breast cancer. Proceedings of the National Academy of Sciences. 118(38). 49 indexed citations

Zhao, Qingchuan, Jean‐Philippe Laverdure, Joël Lanoix, et al.. (2020). Proteogenomics Uncovers a Vast Repertoire of Shared Tumor-Specific Antigens in Ovarian Cancer. Cancer Immunology Research. 8(4). 544–555. 52 indexed citations

Toker, Aras & Pamela S. Ohashi. (2019). Expression of costimulatory and inhibitory receptors in FoxP3+ regulatory T cells within the tumor microenvironment: Implications for combination immunotherapy approaches. Advances in cancer research. 144. 193–261. 24 indexed citations

Saibil, Samuel D., Michael St. Paul, Carlos R. Garcia-Batres, et al.. (2018). Activation of Peroxisome Proliferator-Activated Receptors α and δ Synergizes with Inflammatory Signals to Enhance Adoptive Cell Therapy. Cancer Research. 79(3). 445–451. 57 indexed citations

Toker, Aras, Linh T. Nguyen, Simone C. Stone, et al.. (2018). Regulatory T Cells in Ovarian Cancer Are Characterized by a Highly Activated Phenotype Distinct from that in Melanoma. Clinical Cancer Research. 24(22). 5685–5696. 85 indexed citations

Benveniste, Patricia, Sobhan Roy, Munehide Nakatsugawa, et al.. (2018). Generation and molecular recognition of melanoma-associated antigen-specific human γδ T cells. Science Immunology. 3(30). 56 indexed citations

Shen, Qiang, Brenda Cohen, Ramtin Rahbar, et al.. (2017). Notch Shapes the Innate Immunophenotype in Breast Cancer. Cancer Discovery. 7(11). 1320–1335. 92 indexed citations

Lheureux, Stéphanie, Christophe Denoyelle, Pamela S. Ohashi, Johann S. de Bono, & Felix M. Mottaghy. (2017). Molecularly targeted therapies in cancer: a guide for the nuclear medicine physician. European Journal of Nuclear Medicine and Molecular Imaging. 44(S1). 41–54. 50 indexed citations

10.

Umitsu, Masataka, Charles W. Tran, Noboru Ishiyama, et al.. (2016). An interaction between Scribble and the NADPH oxidase complex controls M1 macrophage polarization and function. Nature Cell Biology. 18(11). 1244–1252. 40 indexed citations

11.

Rahbar, Ramtin, Albert Lin, Magar Ghazarian, et al.. (2014). B7-H4 Expression by Nonhematopoietic Cells in the Tumor Microenvironment Promotes Antitumor Immunity. Cancer Immunology Research. 3(2). 184–195. 38 indexed citations

12.

Johnson, Dylan, Lily Pao, Salim Dhanji, et al.. (2013). Shp1 regulates T cell homeostasis by limiting IL-4 signals. The Journal of Experimental Medicine. 210(7). 1419–1431. 79 indexed citations

13.

Chatterjee, Samit, Michael E. Feigin, Don L. Gibbons, et al.. (2012). Dysregulation of Cell Polarity Proteins Synergize with Oncogenes or the Microenvironment to Induce Invasive Behavior in Epithelial Cells. PLoS ONE. 7(4). e34343–e34343. 30 indexed citations

14.

Mulligan, Anna Marie, Irene Raitman, Linda Feeley, et al.. (2012). Tumoral Lymphocytic Infiltration and Expression of the Chemokine CXCL10 in Breast Cancers from the Ontario Familial Breast Cancer Registry. Clinical Cancer Research. 19(2). 336–346. 116 indexed citations

15.

McIlwain, David R., Philipp A. Lang, Thorsten Maretzky, et al.. (2012). iRhom2 Regulation of TACE Controls TNF-Mediated Protection Against Listeria and Responses to LPS. Science. 335(6065). 229–232. 259 indexed citations

16.

Quintela-Fandiño, Miguel, Enrico Arpaia, Dirk Brenner, et al.. (2010). HUNK suppresses metastasis of basal type breast cancers by disrupting the interaction between PP2A and cofilin-1. Proceedings of the National Academy of Sciences. 107(6). 2622–2627. 37 indexed citations

17.

Pellegrini, Marc, Thomas Calzascia, Alisha R. Elford, et al.. (2009). Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies. Nature Medicine. 15(5). 528–536. 171 indexed citations

18.

Chau, Hien, Veronica Wong, Nien‐Jung Chen, et al.. (2005). Cellular FLICE-inhibitory protein is required for T cell survival and cycling. The Journal of Experimental Medicine. 202(3). 405–413. 72 indexed citations

19.

Mariathasan, Sanjeev, Martin F. Bachmann, Denis Bouchard, Toshiaki Ohteki, & Pamela S. Ohashi. (1998). Degree of TCR Internalization and Ca2+ Flux Correlates with Thymocyte Selection. The Journal of Immunology. 161(11). 6030–6037. 42 indexed citations

20.

Bachmann, Martin F., Sanjeev Mariathasan, Denis Bouchard, Daniel E. Speiser, & Pamela S. Ohashi. (1997). Four types of Ca²⁺ signals in naive CD8⁺ cytotoxic T cells after stimulation with T cell agonists, partial agonists and antagonists. European Journal of Immunology. 27(12). 3414–3419. 23 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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