Andrew Wakeham

46.2k total citations · 22 hit papers
112 papers, 31.5k citations indexed

About

Andrew Wakeham is a scholar working on Molecular Biology, Immunology and Oncology. According to data from OpenAlex, Andrew Wakeham has authored 112 papers receiving a total of 31.5k indexed citations (citations by other indexed papers that have themselves been cited), including 67 papers in Molecular Biology, 51 papers in Immunology and 32 papers in Oncology. Recurrent topics in Andrew Wakeham's work include Immune Cell Function and Interaction (21 papers), T-cell and B-cell Immunology (18 papers) and NF-κB Signaling Pathways (16 papers). Andrew Wakeham is often cited by papers focused on Immune Cell Function and Interaction (21 papers), T-cell and B-cell Immunology (18 papers) and NF-κB Signaling Pathways (16 papers). Andrew Wakeham collaborates with scholars based in Canada, United States and Japan. Andrew Wakeham's co-authors include Tak W. Mak, Pamela S. Ohashi, Tak W. Mak, Andrew Elia, Josef Penninger, Arda Shahinian, Thomas M. Kündig, Annick Itié, Gordon S. Duncan and José Luís de la Pompa and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Andrew Wakeham

111 papers receiving 30.9k citations

Hit Papers

OPGL is a key regulator of osteoclastogenesis, lymphocyte... 1991 2026 2002 2014 1999 1993 2001 1993 2000 500 1000 1.5k 2.0k 2.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
    1999 2.7k citations Young‐Yun Kong, Ildiko Sarosi et al. Nature profile →
  2. Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection
    1993 1.5k citations Andrew Wakeham, Arda Shahinian et al. Cell profile →
  3. Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death
    2001 1.1k citations Takehiko Sasaki, Andrew Elia et al. Nature profile →
  4. Differential T Cell Costimulatory Requirements in CD28-Deficient Mice
    1993 1.1k citations Arda Shahinian, Andrew Wakeham et al. Science profile →
  5. DNA Damage-Induced Activation of p53 by the Checkpoint Kinase Chk2
    2000 1.0k citations Young‐Yun Kong, Andrew Wakeham et al. Science profile →
  6. Function of PI3Kγ in Thymocyte Development, T Cell Activation, and Neutrophil Migration
    2000 889 citations Takehiko Sasaki, Andrew Wakeham et al. Science profile →
  7. Profound block in thymocyte development in mice lacking p56lck
    1992 867 citations Andrew Wakeham, Tak W. Mak et al. Nature profile →
  8. FADD: Essential for Embryo Development and Signaling from Some, But Not All, Inducers of Apoptosis
    1998 759 citations Wen‐Chen Yeh, José Luís de la Pompa et al. Science profile →
  9. Deregulated T Cell Activation and Autoimmunity in Mice Lacking Interleukin-2 Receptor β
    1995 727 citations Andrew Wakeham, Pamela S. Ohashi et al. Science profile →
  10. Early Lethality, Functional NF-κB Activation, and Increased Sensitivity to TNF-Induced Cell Death in TRAF2-Deficient Mice
    1997 705 citations Wen-Chen Yeh, Arda Shahinian et al. Immunity profile →
  11. High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice
    1998 665 citations José Luís de la Pompa, Vuk Stambolic et al. profile →
  12. Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4
    2002 650 citations Nobutaka Suzuki, Gordon S. Duncan et al. Nature profile →
  13. Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4
    1991 603 citations Andrew Wakeham, Tak W. Mak et al. Nature profile →
  14. Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress
    2005 566 citations Andrew Wakeham, Annick You-Ten et al. Proceedings of the National Academy of Sciences profile →
  15. Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development
    1993 566 citations Andrew Wakeham, Pamela S. Ohashi et al. Cell profile →
  16. ICOS is essential for effective T-helper-cell responses
    2001 558 citations Agostino Tafuri, Arda Shahinian et al. Nature profile →
  17. Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b
    2000 553 citations Kurt Bachmaier, Connie M. Krawczyk et al. Nature profile →
  18. The Tumor Suppressor Gene Brca1 Is Required for Embryonic Cellular Proliferation in the Mouse
    1996 530 citations Razqallah Hakem, José Luís de la Pompa et al. Cell profile →
  19. Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum
    1998 517 citations José Luís de la Pompa, Hiroaki Takimoto et al. Nature profile →
  20. Conservation of the Notch signalling pathway in mammalian neurogenesis
    1997 513 citations José Luís de la Pompa, Andrew Wakeham et al. profile →
  21. T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance
    2001 463 citations Toshiaki Ohteki, Takehiko Sasaki et al. Immunity profile →
  22. Disruption of the mouse RBP-Jк gene results in early embryonic death
    1995 419 citations Andrew Wakeham, José Luís de la Pompa et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Andrew Wakeham Canada 73 17.3k 13.3k 7.9k 5.6k 2.2k 112 31.5k
Daniel G. Tenen United States 98 20.3k 1.2× 8.7k 0.7× 7.3k 0.9× 4.8k 0.8× 2.4k 1.1× 368 33.7k
Pamela S. Ohashi Canada 93 10.1k 0.6× 23.0k 1.7× 7.2k 0.9× 3.8k 0.7× 2.9k 1.3× 317 33.6k
Atsushi Miyajima Japan 84 10.3k 0.6× 10.2k 0.8× 8.7k 1.1× 2.5k 0.4× 1.7k 0.8× 364 26.6k
Elisabeth Kremmer Germany 96 14.5k 0.8× 8.1k 0.6× 5.8k 0.7× 2.7k 0.5× 1.8k 0.8× 428 28.9k
Malcolm A.S. Moore United States 82 13.2k 0.8× 7.4k 0.6× 7.6k 1.0× 3.2k 0.6× 2.7k 1.2× 337 28.5k
Ulrich Siebenlist United States 73 10.6k 0.6× 10.5k 0.8× 4.3k 0.5× 7.5k 1.3× 1.8k 0.8× 176 22.4k
Peter Angel Germany 75 17.7k 1.0× 5.1k 0.4× 5.9k 0.8× 6.1k 1.1× 3.7k 1.7× 186 29.1k
Manolis Pasparakis Germany 84 13.4k 0.8× 12.3k 0.9× 4.3k 0.5× 5.8k 1.0× 2.0k 0.9× 193 26.6k
Akihiko Yoshimura Japan 82 10.6k 0.6× 11.3k 0.9× 7.0k 0.9× 3.1k 0.5× 1.7k 0.8× 349 27.4k
Hal E. Broxmeyer United States 89 10.1k 0.6× 12.3k 0.9× 9.6k 1.2× 2.2k 0.4× 2.4k 1.1× 570 30.4k

Countries citing papers authored by Andrew Wakeham

Since Specialization
Citations

This map shows the geographic impact of Andrew Wakeham's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Andrew Wakeham with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Andrew Wakeham more than expected).

Fields of papers citing papers by Andrew Wakeham

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Andrew Wakeham. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Andrew Wakeham. The network helps show where Andrew Wakeham may publish in the future.

Co-authorship network of co-authors of Andrew Wakeham

This figure shows the co-authorship network connecting the top 25 collaborators of Andrew Wakeham. A scholar is included among the top collaborators of Andrew Wakeham based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Andrew Wakeham. Andrew Wakeham is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Nechanitzky, Robert, Parameswaran Ramachandran, Wanda Y. Li, et al.. (2024). CaSSiDI: novel single-cell “Cluster Similarity Scoring and Distinction Index” reveals critical functions for PirB and context-dependent Cebpb repression. Cell Death and Differentiation. 31(3). 265–279. 2 indexed citations
2.
Nechanitzky, Robert, Parameswaran Ramachandran, Gordon S. Duncan, et al.. (2022). Cholinergic control of Th17 cell pathogenicity in experimental autoimmune encephalomyelitis. Cell Death and Differentiation. 30(2). 407–416. 9 indexed citations
3.
Lukhele, Sabelo, Mengdi Guo, Jian Shen, et al.. (2022). The transcription factor IRF2 drives interferon-mediated CD8+ T cell exhaustion to restrict anti-tumor immunity. Immunity. 55(12). 2369–2385.e10. 67 indexed citations
4.
Bassi, C., Jérôme Fortin, Bryan E. Snow, et al.. (2021). The PTEN and ATM axis controls the G1/S cell cycle checkpoint and tumorigenesis in HER2-positive breast cancer. Cell Death and Differentiation. 28(11). 3036–3051. 21 indexed citations
5.
Cox, Maureen A., Gordon S. Duncan, Gloria Lin, et al.. (2019). Choline acetyltransferase–expressing T cells are required to control chronic viral infection. Science. 363(6427). 639–644. 105 indexed citations
6.
McIlwain, David R., Philipp A. Lang, Thorsten Maretzky, et al.. (2012). iRhom2 Regulation of TACE Controls TNF-Mediated Protection Against Listeria and Responses to LPS. Science. 335(6065). 229–232. 259 indexed citations
7.
McIlwain, David R., Qun Pan, Patrick T. Reilly, et al.. (2010). Smg1 is required for embryogenesis and regulates diverse genes via alternative splicing coupled to nonsense-mediated mRNA decay. Proceedings of the National Academy of Sciences. 107(27). 12186–12191. 154 indexed citations
8.
Quintela-Fandiño, Miguel, Enrico Arpaia, Dirk Brenner, et al.. (2010). HUNK suppresses metastasis of basal type breast cancers by disrupting the interaction between PP2A and cofilin-1. Proceedings of the National Academy of Sciences. 107(6). 2622–2627. 37 indexed citations
9.
Sasaki, Toru, Eugene Gan, Andrew Wakeham, et al.. (2007). HLA-B-associated transcript 3 (Bat3)/Scythe is essential for p300-mediated acetylation of p53. Genes & Development. 21(7). 848–861. 106 indexed citations
10.
Berger, Thorsten, Atsushi Togawa, Gordon S. Duncan, et al.. (2006). Lipocalin 2-deficient mice exhibit increased sensitivity to Escherichia coli infection but not to ischemia-reperfusion injury. Proceedings of the National Academy of Sciences. 103(6). 1834–1839. 380 indexed citations
11.
Chau, Hien, Veronica Wong, Nien‐Jung Chen, et al.. (2005). Cellular FLICE-inhibitory protein is required for T cell survival and cycling. The Journal of Experimental Medicine. 202(3). 405–413. 72 indexed citations
12.
Hao, Zhenyue, Gordon S. Duncan, Chia‐Che Chang, et al.. (2005). Specific Ablation of the Apoptotic Functions of Cytochrome c Reveals a Differential Requirement for Cytochrome c and Apaf-1 in Apoptosis. Cell. 121(4). 579–591. 213 indexed citations
13.
Suh, Woong‐Kyung, Agostino Tafuri, Arda Shahinian, et al.. (2004). The Inducible Costimulator Plays the Major Costimulatory Role in Humoral Immune Responses in the Absence of CD28. The Journal of Immunology. 172(10). 5917–5923. 47 indexed citations
14.
Hara, Hiromitsu, Atsunobu Takeda, Andrew Wakeham, et al.. (2002). The Apoptotic Protease-Activating Factor 1-Mediated Pathway of Apoptosis Is Dispensable for Negative Selection of Thymocytes. The Journal of Immunology. 168(8). 4241–4241. 1 indexed citations
15.
Leco, Kevin J., Paul Waterhouse, Otto Sánchez, et al.. (2001). Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3). Journal of Clinical Investigation. 108(6). 817–829. 187 indexed citations
16.
Leco, Kevin J., Paul Waterhouse, Otto Sánchez, et al.. (2001). Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3). Journal of Clinical Investigation. 108(6). 817–829. 201 indexed citations
17.
Ruland, Jürgen, Christian Sirard, Andrew Elia, et al.. (2001). p53 Accumulation, defective cell proliferation, and early embryonic lethality in mice lacking tsg101. Proceedings of the National Academy of Sciences. 98(4). 1859–1864. 126 indexed citations
18.
Yeh, Wen‐Chen, Annick Itié, Andrew Elia, et al.. (2000). Requirement for Casper (c-FLIP) in Regulation of Death Receptor–Induced Apoptosis and Embryonic Development. Immunity. 12(6). 633–642. 409 indexed citations
19.
Bachmaier, Kurt, Connie M. Krawczyk, I. Kozieradzki, et al.. (2000). Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b. Nature. 403(6766). 211–216. 553 indexed citations breakdown →
20.
Yoshida, Hiroki, Hiroshi Nishina, Hiroaki Takimoto, et al.. (1998). The Transcription Factor NF-ATc1 Regulates Lymphocyte Proliferation and Th2 Cytokine Production. Immunity. 8(1). 115–124. 300 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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