Kenneth Siddle

10.5k total citations · 1 hit paper
165 papers, 8.6k citations indexed

About

Kenneth Siddle is a scholar working on Molecular Biology, Surgery and Endocrinology, Diabetes and Metabolism. According to data from OpenAlex, Kenneth Siddle has authored 165 papers receiving a total of 8.6k indexed citations (citations by other indexed papers that have themselves been cited), including 109 papers in Molecular Biology, 49 papers in Surgery and 42 papers in Endocrinology, Diabetes and Metabolism. Recurrent topics in Kenneth Siddle's work include Metabolism, Diabetes, and Cancer (50 papers), Pancreatic function and diabetes (47 papers) and Protein Kinase Regulation and GTPase Signaling (29 papers). Kenneth Siddle is often cited by papers focused on Metabolism, Diabetes, and Cancer (50 papers), Pancreatic function and diabetes (47 papers) and Protein Kinase Regulation and GTPase Signaling (29 papers). Kenneth Siddle collaborates with scholars based in United Kingdom, United States and Australia. Kenneth Siddle's co-authors include Maria A. Soos, Peter R. Shepherd, Dominic J. Withers, J. Paul Luzio, B. Nave, Carola U. Niesler, C. E. Field, Richard M. O’Brien, Stephen O’Rahilly and A. Ullrich and has published in prestigious journals such as Proceedings of the National Academy of Sciences, The Lancet and Nucleic Acids Research.

In The Last Decade

Kenneth Siddle

163 papers receiving 8.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling

1998 798 citations Peter R. Shepherd, Kenneth Siddle et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Kenneth Siddle United Kingdom	50	5.9k	2.5k	2.0k	1.4k	779	165	8.6k
Yehiel Zick Israel	48	6.1k 1.0×	1.5k 0.6×	1.5k 0.7×	1.8k 1.3×	956 1.2×	124	9.5k
O M Rosen United States	55	9.2k 1.6×	1.6k 0.7×	2.3k 1.1×	2.0k 1.4×	1.5k 2.0×	127	12.1k
Arnold W. Strauss United States	58	6.4k 1.1×	946 0.4×	1.2k 0.6×	1.6k 1.2×	868 1.1×	220	10.5k
Emmanuel Van Obberghen France	54	6.1k 1.0×	1.4k 0.6×	2.0k 1.0×	2.0k 1.4×	1.1k 1.5×	150	9.7k
Éric Clauser France	51	5.5k 0.9×	3.1k 1.2×	2.1k 1.0×	407 0.3×	539 0.7×	145	9.8k
Xiao‐Jian Sun United States	51	8.1k 1.4×	1.9k 0.8×	1.9k 0.9×	1.7k 1.2×	1.1k 1.4×	127	11.4k
P Freychet France	47	4.1k 0.7×	1.4k 0.6×	2.4k 1.2×	1.8k 1.3×	1.0k 1.3×	159	7.2k
Jørgen Gliemann Denmark	58	5.4k 0.9×	1.1k 0.5×	1.7k 0.8×	3.1k 2.2×	2.0k 2.6×	156	10.7k
Chieko Mineo United States	44	3.6k 0.6×	1.3k 0.5×	1.7k 0.8×	1.1k 0.8×	1.6k 2.1×	106	7.7k
Vassilis I. Zannis United States	55	5.3k 0.9×	3.4k 1.4×	4.6k 2.3×	1.1k 0.8×	609 0.8×	192	10.5k

Countries citing papers authored by Kenneth Siddle

Since Specialization

Citations

This map shows the geographic impact of Kenneth Siddle's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kenneth Siddle with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kenneth Siddle more than expected).

Fields of papers citing papers by Kenneth Siddle

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kenneth Siddle. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kenneth Siddle. The network helps show where Kenneth Siddle may publish in the future.

Co-authorship network of co-authors of Kenneth Siddle

This figure shows the co-authorship network connecting the top 25 collaborators of Kenneth Siddle. A scholar is included among the top collaborators of Kenneth Siddle based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Kenneth Siddle. Kenneth Siddle is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Brierley, Gemma V., Kenneth Siddle, & Robert K. Semple. (2018). Evaluation of anti-insulin receptor antibodies as potential novel therapies for human insulin receptoropathy using cell culture models. Diabetologia. 61(7). 1662–1675. 7 indexed citations

Martin‐Gronert, Malgorzata S., Denise S. Fernandez‐Twinn, Martin Bushell, Kenneth Siddle, & Susan E. Ozanne. (2016). Cell-autonomous programming of rat adipose tissue insulin signalling proteins by maternal nutrition. Diabetologia. 59(6). 1266–1275. 11 indexed citations

Siddle, Kenneth. (2012). Molecular Basis of Signaling Specificity of Insulin and IGF Receptors: Neglected Corners and Recent Advances. Frontiers in Endocrinology. 3. 34–34. 117 indexed citations

Hadaschik, Dirk, et al.. (2009). The transcription factors Egr1 and Egr2 have opposing influences on adipocyte differentiation. Cell Death and Differentiation. 16(5). 782–789. 79 indexed citations

Surinya, Kathy H., Briony E. Forbes, Grant W. Booker, et al.. (2007). An Investigation of the Ligand Binding Properties and Negative Cooperativity of Soluble Insulin-like Growth Factor Receptors. Journal of Biological Chemistry. 283(9). 5355–5363. 36 indexed citations

Ursø, Birgitte, Carola U. Niesler, Stephen O’Rahilly, & Kenneth Siddle. (2001). Comparison of anti-apoptotic signalling by the insulin receptor and IGF-I receptor in preadipocytes and adipocytes. Cellular Signalling. 13(4). 279–285. 19 indexed citations

Bevan, A. Paul, et al.. (2000). The role of insulin dissociation from its endosomal receptor in insulin degradation. Molecular and Cellular Endocrinology. 164(1-2). 145–157. 8 indexed citations

Ursø, Birgitte, Richard A. Brown, Stephen O’Rahilly, Peter R. Shepherd, & Kenneth Siddle. (1999). The α‐isoform of class II phosphoinositide 3‐kinase is more effectively activated by insulin receptors than IGF receptors, and activation requires receptor NPEY motifs. FEBS Letters. 460(3). 423–426. 22 indexed citations

Ursø, Birgitte, Diane L. Cope, Amanda C. Hayward, et al.. (1999). Differences in Signaling Properties of the Cytoplasmic Domains of the Insulin Receptor and Insulin-like Growth Factor Receptor in 3T3-L1 Adipocytes. Journal of Biological Chemistry. 274(43). 30864–30873. 53 indexed citations

10.

Niesler, Carola U., Kenneth Siddle, & Johannes B. Prins. (1998). Human Preadipocytes Display a Depot-Specific Susceptibility to Apoptosis. Diabetes. 47(8). 1365–1368. 96 indexed citations

11.

Marino‐Buslje, Cristina, Kenji Mizuguchi, Kenneth Siddle, & Tom L. Blundell. (1998). A third fibronectin type III domain in the extracellular region of the insulin receptor family. FEBS Letters. 441(2). 331–336. 26 indexed citations

12.

Shepherd, Peter R., B. Nave, Jorge Rincón, et al.. (1997). Differential Regulation of Phosphoinositide 3-Kinase Adapter Subunit Variants by Insulin in Human Skeletal Muscle. Journal of Biological Chemistry. 272(30). 19000–19007. 50 indexed citations

13.

Whitehead, Jonathan P., et al.. (1997). Differential Signaling to Glycogen Synthesis by the Intracellular Domain of the Insulin versus the Insulin-like Growth Factor-1 Receptor. Journal of Biological Chemistry. 272(39). 24325–24332. 28 indexed citations

14.

Krook, Anna, et al.. (1996). Functional activation of mutant human insulin receptor by monoclonal antibody. The Lancet. 347(9015). 1586–1590. 20 indexed citations

15.

Mosthaf, Luitgard, Lucia Berti, Monika Kellerer, et al.. (1995). C-Terminus or Juxtamembrane Deletions in the Insulin Receptor do not Affect the Glucose-Dependent Inhibition of the Tyrosine Kinase Activity. European Journal of Biochemistry. 227(3). 787–791. 5 indexed citations

16.

Soos, Maria A., B. Nave, & Kenneth Siddle. (1994). Immunological Studies of Type I IGF Receptors and Insulin Receptors: Characterisation of Hybrid and Atypical Receptor Subtypes. Advances in experimental medicine and biology. 343. 145–157. 18 indexed citations

17.

Kahn, C. Ronald, Morris F. White, Steven E. Shoelson, et al.. (1993). The Insulin Receptor and Its Substrate: Molecular Determinants of Early Events in Insulin Action. PubMed. 48. 291–339. 78 indexed citations

18.

Backer, Jonathan, et al.. (1991). Cytoplasmic juxtamembrane region of the insulin receptor: a critical role in ATP binding, endogenous substrate phosphorylation, and insulin-stimulated bioeffects in CHO cells. Biochemistry. 30(26). 6366–6372. 36 indexed citations

19.

O’Brien, Richard M., Miles D. Houslay, Nicholas P.J. Brindle, et al.. (1989). Binding to GDP-agarose identifies a novel 60kDa substrate for the insulin receptor tyrosyl kinase in mouse NIH-3T3 cells expressing high concentrations of the human insulin receptor. Biochemical and Biophysical Research Communications. 158(3). 743–748. 10 indexed citations

20.

Bar, Robert S., et al.. (1988). Actions of insulin and insulinlike growth factors I and II in cultured microvessel endothelial cells from bovine adipose tissue. Metabolism. 37(8). 714–720. 34 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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