Richard M. O’Brien

9.6k citations

150 papers · 6.7k · h-index 47

Impact in

Immunology and Allergy top 1%
- Allergic Rhinitis and Sensitization
- Food Allergy and Anaphylaxis Research
Aging top 2%

Papers in

Molecular Biology 77
- Metabolism, Diabetes, and Cancer 49
Surgery 57
- Pancreatic function and diabetes 54

Co-authors: Daryl K. Granner (9 shared papers)D. K. Granner (1 shared paper)D K Granner (10 shared papers)Peter C. Lucas (6 shared papers)James K. Oeser (39 shared papers)Wayne R. Thomas (8 shared papers)Christina A. Svitek (18 shared papers)John C. Hutton (14 shared papers)
Journals: Journal of Biological Chemistry (19 papers)Diabetes (9 papers)Biochemical Journal (9 papers)Journal of Organizational Behavior Management (6 papers)Molecular Endocrinology (6 papers)
Partner nations: United States Australia United Kingdom

In The Last Decade

Richard M. O’Brien

147 papers receiving 6.5k citations

Peers

Countries citing papers authored by Richard M. O’Brien

Since Specialization

Citations

This map shows the geographic impact of Richard M. O’Brien's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Richard M. O’Brien with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Richard M. O’Brien more than expected).

Fields of papers citing papers by Richard M. O’Brien

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Richard M. O’Brien. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Richard M. O’Brien. The network helps show where Richard M. O’Brien may publish in the future.

Co-authors

The 25 scholars most cited alongside Richard M. O’Brien, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Richard M. O’Brien Line = papers co-authored together Richard M. O’Brien links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 150 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Regulation of gene expression by insulin Physiological Reviews ·Richard M. O’Brien, D. K. Granner	1996	452
2	Identification of a Sequence in the PEPCK Gene That Mediates a Negative Effect of Insulin on Transcription Science ·Richard M. O’Brien, Peter C. Lucas, Claude Forest, Mark A. Magnuson, Daryl K. Granner	1990	327
3	Characterization and Immunobiology of House Dust Mite Allergens International Archives of Allergy and Immunology ·Wayne R. Thomas, Wendy-Anne Smith, Belinda J. Hales, K.L. Mills, Richard M. O’Brien	2002	279
4	Regulation of gene expression by insulin Biochemical Journal ·Richard M. O’Brien, D K Granner	1991	250
5	Regulation of Phosphoenolpyruvate Carboxykinase and Insulin-like Growth Factor-binding Protein-1 Gene Expression by Insulin Journal of Biological Chemistry ·Robert K. Hall, Tomoyuki Yamasaki, Tomáš Kučera, Mary Waltner‐Law, Richard M. O’Brien, Daryl K. Granner	2000	236
6	Hepatic Nuclear Factor 3- and Hormone-Regulated Expression of the Phosphoenolpyruvate Carboxykinase and Insulin-Like Growth Factor-Binding Protein 1 Genes Molecular and Cellular Biology ·Richard M. O’Brien, Edouard L. Noisin, Adisak Suwanichkul, Tomoyuki Yamasaki, Peter C. Lucas, Jen-Chywan Wang, D.R. Powell, Daryl K. Granner	1995	200
7	Mycophenolate mofetil: A safe and promising immunosuppressant in neuromuscular diseases Neurology ·Vinay Chaudhry, David R. Cornblath, John W. Griffin, Richard M. O’Brien, D. B. Drachman	2001	184
8	Insulin-regulated gene expression Biochemical Society Transactions ·Richard M. O’Brien, Ryan S. Streeper, J. E. Ayala, B. T. Stadelmaier, Lauri A. Hornbuckle	2001	158
9	Glucose-6-phosphatase Catalytic Subunit Gene Family Journal of Biological Chemistry ·John C. Hutton, Richard M. O’Brien	2009	150
10	Deletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretion Biochemical Journal ·Lynley D. Pound, Suparna A. Sarkar, Richard K.P. Benninger, Yingda Wang, Adisak Suwanichkul, Melanie K. Shadoan, Richard L. Printz, James K. Oeser, Catherine E. Lee, David W. Piston, Owen P. McGuinness, John C. Hutton, D.R. Powell, Richard M. O’Brien	2009	133
11	Phosphatidylinositol 3-Kinase, but Not p70/p85 Ribosomal S6 Protein Kinase, Is Required for the Regulation of Phosphoenolpyruvate Carboxykinase (PEPCK) Gene Expression by Insulin Journal of Biological Chemistry ·Calum Sutherland, Richard M. O’Brien, Daryl K. Granner	1995	130
12	A Multicomponent Insulin Response Sequence Mediates a Strong Repression of Mouse Glucose-6-phosphatase Gene Transcription by Insulin Journal of Biological Chemistry ·Ryan S. Streeper, Christina A. Svitek, Stacey C. Chapman, Linda E. Greenbaum, Rebecca Taub, Richard M. O’Brien	1997	128
13	A retinoic acid response element is part of a pleiotropic domain in the phosphoenolpyruvate carboxykinase gene. Proceedings of the National Academy of Sciences ·Peter C. Lucas, Richard M. O’Brien, Jennifer A. Mitchell, Charles M. Davis, Enyu Imai, Barry M. Forman, Herbert H. Samuels, D K Granner	1991	126
14	Zinc transporter 8 (ZnT8) and β cell function Trends in Endocrinology and Metabolism ·Howard W. Davidson, Janet M. Wenzlau, Richard M. O’Brien	2014	119
15	Insulin Regulation of Phosphoenolpyruvate Carboxykinase Gene Expression Does Not Require Activation of the Ras/Mitogen-activated Protein Kinase Signaling Pathway Journal of Biological Chemistry ·Robert A. Gabbay, Calum Sutherland, Luigi Gnudi, Barbara B. Kahn, Richard M. O’Brien, Daryl K. Granner, Jeffrey S. Flier	1996	119
16	The Glucose-6-Phosphatase Catalytic Subunit Gene Promoter Contains Both Positive and Negative Glucocorticoid Response Elements Molecular Endocrinology ·Beth T. Vander Kooi, Hiroshi Onuma, James K. Oeser, Christina A. Svitek, Shelley R. Allen, Craig W. Vander Kooi, Walter Chazin, Richard M. O’Brien	2005	112
17	The insulin receptor tyrosyl kinase phosphorylates holomeric forms of the guanine nucleotide regulatory proteins G_i and G_o FEBS Letters ·Richard M. O’Brien, Miles D. Houslay, Graeme Milligan, Kenneth Siddle	1987	112
18	Integration of GWAS SNPs and tissue specific expression profiling reveal discrete eQTLs for human traits in blood and brain Neurobiology of Disease ·Dena Hernández, Mike A. Nalls, Matthew Moore, Sean Chong, Allissa Dillman, Daniah Trabzuni, J. Raphael Gibbs, Mina Ryten, Sampath Arepalli, Michael E. Weale, Alan B. Zonderman, Juan C. Troncoso, Richard M. O’Brien, Robert Walker, Colin Smith, Stefania Bandinelli, Bryan J. Traynor, John Hardy, Andrew B. Singleton, Mark Cookson	2012	100
19	Regulation of Phosphoenolpyruvate Carboxykinase Gene Expression by Insulin. Use of the Stable Transfection Approach to Locate an Insulin Responsive Sequence Molecular Endocrinology ·Claude Forest, Richard M. O’Brien, Peter C. Lucas, Mark A. Magnuson, Daryl K. Granner	1990	99
20	Insulin’s direct hepatic effect explains the inhibition of glucose production caused by insulin secretion JCI Insight ·Dale S. Edgerton, Guillaume Kraft, Marta S. Smith, Ben Farmer, Phillip E. Williams, Katie C. Coate, Richard L. Printz, Richard M. O’Brien, Alan D. Cherrington	2017	97

About Richard M. O’Brien

Richard M. O’Brien is a scholar working on Molecular Biology, Surgery, Genetics, Rheumatology and Physiology, having authored 150 papers that have together received 6.7k indexed citations. Recurring topics across this work include Pancreatic function and diabetes (54 papers), Metabolism, Diabetes, and Cancer (49 papers), Glycogen Storage Diseases and Myoclonus (17 papers), Diabetes and associated disorders (16 papers), Genetics and Neurodevelopmental Disorders (13 papers), Allergic Rhinitis and Sensitization (12 papers), Food Allergy and Anaphylaxis Research (11 papers) and Asthma and respiratory diseases (9 papers). The work is most often cited by research in Immunology and Allergy (551 citations), Aging (156 citations), Endocrinology, Diabetes and Metabolism (911 citations), Molecular Biology (3.7k citations) and Physiology (1.3k citations). Richard M. O’Brien has collaborated with scholars based in United States, Australia and United Kingdom. Frequent co-authors include Daryl K. Granner, D. K. Granner, D K Granner, Peter C. Lucas, James K. Oeser, Wayne R. Thomas, Christina A. Svitek, John C. Hutton, Ryan S. Streeper and Kenneth Siddle. Their work appears in journals such as Journal of Biological Chemistry, Diabetes, Biochemical Journal, Journal of Organizational Behavior Management and Molecular Endocrinology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Richard M. O’Brien

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