Kenneth J. Linton

4.5k citations

46 papers · 3.5k indexed · 1 hit paper · h-index 28

Oncology top 1%
- Drug Transport and Resistance Mechanisms 31
Molecular Medicine top 2%
Physiology top 5%
Nutrition and Dietetics top 5%
- Trace Elements in Health 5
Molecular Biology top 5%
- RNA Interference and Gene Delivery 4
- Protein Interaction Studies and Fluorescence Analysis 4
Infectious Diseases
- HIV/AIDS drug development and treatment 9
Surgery
- Pediatric Hepatobiliary Diseases and Treatments 8
Pediatrics, Perinatology and Child Health
- Pharmacological Effects and Toxicity Studies 4
Pharmaceutical Science
- Drug Solubulity and Delivery Systems 3

Co-authors: Christopher F. Higgins C Wooding Joseph K. Zolnerciks Edward J. Andress Marco Falasca Richard J. Thompson Jane A. Byrne Sandra Strautnieks
Cited by: Oncology Molecular Medicine Physiology
Journals: Journal of Biological Chemistry (2 papers)Nature Communications (1 paper)Gastroenterology (2 papers)
Partner nations: United Kingdom United States Italy

In The Last Decade

Kenneth J. Linton

46 papers receiving 3.4k citations

Hit Papers

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Peers

Countries citing papers authored by Kenneth J. Linton

Since Specialization

Citations

This map shows the geographic impact of Kenneth J. Linton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kenneth J. Linton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kenneth J. Linton more than expected).

Fields of papers citing papers by Kenneth J. Linton

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kenneth J. Linton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kenneth J. Linton. The network helps show where Kenneth J. Linton may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Kenneth J. Linton, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Kenneth J. Linton Line = papers co-authored together Kenneth J. Linton links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Structural basis for the modulation of MRP2 activity by phosphorylation and drugs Nature Communications ·Tiziano Mazza,Theodoros I. Roumeliotis,Elena Garitta,David Drew,S. Tamir Rashid,Cesare Indiveri,Jyoti S. Choudhary,Kenneth J. Linton,Konstantinos Beis	2024	13
2	Molecular Modeling Studies to Probe the Binding Hypothesis of Novel Lead Compounds against Multidrug Resistance Protein ABCB1 Biomolecules ·Yasmeen Cheema,Kenneth J. Linton,Ishrat Jabeen	2024	6
3	Identification and Empiric Evaluation of New Inhibitors of the Multidrug Transporter P-Glycoprotein (ABCB1) International Journal of Molecular Sciences ·Yasmeen Cheema,Yusra Sajid Kiani,Kenneth J. Linton,Ishrat Jabeen	2023	7
4	Identification of CD36 as a new interaction partner of membrane NEU1: potential implication in the pro-atherogenic effects of the elastin receptor complex Cellular and Molecular Life Sciences ·Charlotte Kawecki,Olivier Bocquet,Christian E.H. Schmelzer,Andrea Heinz,Christian Ihling,Amandine Wahart,Béatrice Romier,Amar Bennasroune,Sébastien Blaise,Christine Terryn,Kenneth J. Linton,Laurent Martiny,Laurent Duca,Pascal Maurice	2018	38
5	ABCB4 missense mutations D243A, K435T, G535D, I490T, R545C, and S978P significantly impair the lipid floppase and likely predispose to secondary pathologies in the human population Cellular and Molecular Life Sciences ·Edward J. Andress,Michael Nicolaou,Farrell McGeoghan,Kenneth J. Linton	2017	12
6	Inactive alleles of cytochrome P450 2C19 may be positively selected in human evolution BMC Evolutionary Biology ·Ramatoulie E Janha,Archibald Worwui,Kenneth J. Linton,Seif O. Shaheen,Fatoumatta Sisay-Joof,Robert Walton	2014	12
7	Mutations in AQP5, Encoding a Water-Channel Protein, Cause Autosomal-Dominant Diffuse Nonepidermolytic Palmoplantar Keratoderma The American Journal of Human Genetics ·Diana C. Blaydon,Lisbet K. Lind,Vincent Plagnol,Kenneth J. Linton,Francis J. Smith,Neil Wilson,W.H. Irwin McLean,Colin S. Munro,Andrew P. South,Irene M. Leigh,Edel A. O’Toole,Anita Lundström,David P. Kelsell	2013	59
8	Molecular Mechanistic Explanation for the Spectrum of Cholestatic Disease Caused by the S320F Variant of ABCB4 Hepatology ·Edward J. Andress,Michael Nicolaou,Marta R. Romero,Sandhia Naik,Peter Dixon,Catherine Williamson,Kenneth J. Linton	2013	28
9	Missense mutations and single nucleotide polymorphisms in ABCB11 impair bile salt export pump processing and function or disrupt pre-messenger RNA splicing # Hepatology ·Jane A. Byrne,Sandra Strautnieks,Gudrun Ihrke,(unknown),A. S. Knisely,Kenneth J. Linton,Giorgina Mieli‐Vergani,Richard J. Thompson	2008	119
10	Cd36, a class B scavenger receptor, functions as a monomer to bind acetylated and oxidized low‐density lipoproteins Protein Science ·Catherine Martin,Emma Longman,C Wooding,Sarah Hoosdally,Saira Ali,Timothy J. Aitman,Daniel A.P. Gutmann,Paul S. Freemont,Bernadette Byrne,Kenneth J. Linton	2007	33
11	Structure and function of ABC transporters: the ATP switch provides flexible control Pflügers Archiv - European Journal of Physiology ·Kenneth J. Linton,Christopher F. Higgins	2006	168
12	Membrane phosphatidylserine distribution as a non-apoptotic signalling mechanism in lymphocytes Nature Cell Biology ·James I. Elliott,Annmarie Surprenant,Federica M. Marelli‐Berg,Joanne C. Cooper,Robin L. Cassady-Cain,C Wooding,Kenneth J. Linton,Denis R. Alexander,Christopher F. Higgins	2005	194
13	A CD36 nonsense mutation associated with insulin resistance and familial type 2 diabetes Human Mutation ·Frédéric Leprêtre,Francis Vasseur,Martine Vaxillaire,Philipp E. Scherer,Saira Ali,Kenneth J. Linton,Timothy J. Aitman,Philippe Froguel	2004	56
14	The Topography of Transmembrane Segment Six Is Altered during the Catalytic Cycle of P-glycoprotein Journal of Biological Chemistry ·Alice J. Rothnie,Janet Storm,J J R Campbell,Kenneth J. Linton,Ian D. Kerr,Richard Callaghan	2004	51
15	The ATP switch model for ABC transportersbreakdown → Nature Structural & Molecular Biology ·Christopher F. Higgins,Kenneth J. Linton	2004	589
16	Communication between the Nucleotide Binding Domains of P-Glycoprotein Occurs via Conformational Changes that Involve Residue 508 Biochemistry ·Mark P. Gabriel,Janet Storm,Alice J. Rothnie,Andrew M. Taylor,Kenneth J. Linton,Ian D. Kerr,Richard Callaghan	2003	10
17	P-glycoprotein misfolds in Escherichia coli : evidence against alternating-topology models of the transport cycle Molecular Membrane Biology ·Kenneth J. Linton,Christopher F. Higgins	2002	15
18	The human bile salt export pump: Characterization of substrate specificity and identification of inhibitors Gastroenterology ·Jane A. Byrne,Sandra Strautnieks,Giorgina Mieli‐Vergani,Christopher F. Higgins,Kenneth J. Linton,Richard J. Thompson	2002	230
19	The Escherichia coli ATP‐binding cassette (ABC) proteins Molecular Microbiology ·Kenneth J. Linton,Christopher F. Higgins	1998	355
20	Structure of the multidrug resistance P-glycoprotein Seminars in Cancer Biology ·Christopher F. Higgins,Richard Callaghan,Kenneth J. Linton,Mark F. Rosenberg,Robert C. Ford	1997	93

About Kenneth J. Linton

Kenneth J. Linton is a scholar working on Oncology, Molecular Medicine and Pharmaceutical Science, having authored 46 papers that have together received 3.5k indexed citations. Recurring topics across this work include Drug Transport and Resistance Mechanisms (31 papers), HIV/AIDS drug development and treatment (9 papers), Pediatric Hepatobiliary Diseases and Treatments (8 papers), Trace Elements in Health (5 papers), RNA Interference and Gene Delivery (4 papers), Pharmacological Effects and Toxicity Studies (4 papers), Protein Interaction Studies and Fluorescence Analysis (4 papers) and Drug Solubulity and Delivery Systems (3 papers). The work is most often cited by research in Oncology (1.9k citations), Molecular Medicine (227 citations) and Physiology (105 citations). Kenneth J. Linton has collaborated with scholars based in United Kingdom, United States and Italy. Frequent co-authors include Christopher F. Higgins, Christopher F. Higgins, C Wooding, Joseph K. Zolnerciks, Edward J. Andress, Marco Falasca, Richard J. Thompson, Jane A. Byrne, Sandra Strautnieks and Giorgina Mieli‐Vergani. Their work appears in journals such as Journal of Biological Chemistry, Nature Communications and Gastroenterology.

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