Kenneth J. Linton

4.5k citations

46 papers · 3.5k indexed · 1 hit paper · h-index 28

Oncology top 1%
Molecular Biology top 5%
Surgery top 5%
Pediatrics, Perinatology and Child Health top 2%
Infectious Diseases top 5%

Co-authors: Christopher F. Higgins C Wooding Joseph K. Zolnerciks Edward J. Andress Marco Falasca Richard J. Thompson Jane A. Byrne Sandra Strautnieks
Topics: Drug Transport and Resistance Mechanisms (31 papers)HIV/AIDS drug development and treatment (9 papers)Pediatric Hepatobiliary Diseases and Treatments (8 papers)
Cited by: Oncology Molecular Medicine Physiology
Journals: Journal of Biological Chemistry Nature Communications Gastroenterology
Partner nations: United Kingdom United States Italy

In The Last Decade

Kenneth J. Linton

46 papers receiving 3.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The ATP switch model for ABC transporters

2004 589 citations Christopher F. Higgins, Kenneth J. Linton Nature Structural & Molecular Biology profile →

Peers

Countries citing papers authored by Kenneth J. Linton

Since Specialization

Citations

This map shows the geographic impact of Kenneth J. Linton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kenneth J. Linton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kenneth J. Linton more than expected).

Fields of papers citing papers by Kenneth J. Linton

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kenneth J. Linton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kenneth J. Linton. The network helps show where Kenneth J. Linton may publish in the future.

Co-authorship network of co-authors of Kenneth J. Linton

This figure shows the co-authorship network connecting the top 25 collaborators of Kenneth J. Linton. A scholar is included among the top collaborators of Kenneth J. Linton based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Kenneth J. Linton. Kenneth J. Linton is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Structural basis for the modulation of MRP2 activity by phosphorylation and drugs 2024 ·Nature Communications ·(unknown),Theodoros I. Roumeliotis,(unknown),David Drew,S. Tamir Rashid,Cesare Indiveri,Jyoti S. Choudhary,Kenneth J. Linton,Konstantinos Beis	13
2	Molecular Modeling Studies to Probe the Binding Hypothesis of Novel Lead Compounds against Multidrug Resistance Protein ABCB1 2024 ·Biomolecules ·(unknown),Kenneth J. Linton,Ishrat Jabeen	6
3	Identification and Empiric Evaluation of New Inhibitors of the Multidrug Transporter P-Glycoprotein (ABCB1) 2023 ·International Journal of Molecular Sciences ·(unknown),(unknown),Kenneth J. Linton,Ishrat Jabeen	7
4	Identification of CD36 as a new interaction partner of membrane NEU1: potential implication in the pro-atherogenic effects of the elastin receptor complex 2018 ·Cellular and Molecular Life Sciences ·Charlotte Kawecki,(unknown),Christian E.H. Schmelzer,Andrea Heinz,Christian Ihling,(unknown),Béatrice Romier,Amar Bennasroune,Sébastien Blaise,Christine Terryn,Kenneth J. Linton,Laurent Martiny,Laurent Duca,Pascal Maurice	38
5	ABCB4 missense mutations D243A, K435T, G535D, I490T, R545C, and S978P significantly impair the lipid floppase and likely predispose to secondary pathologies in the human population 2017 ·Cellular and Molecular Life Sciences ·Edward J. Andress,Michael Nicolaou,(unknown),Kenneth J. Linton	12
6	Inactive alleles of cytochrome P450 2C19 may be positively selected in human evolution 2014 ·BMC Evolutionary Biology ·(unknown),Archibald Worwui,Kenneth J. Linton,Seif O. Shaheen,Fatoumatta Sisay-Joof,Robert Walton	12
7	Mutations in AQP5, Encoding a Water-Channel Protein, Cause Autosomal-Dominant Diffuse Nonepidermolytic Palmoplantar Keratoderma 2013 ·The American Journal of Human Genetics ·Diana C. Blaydon,Lisbet K. Lind,Vincent Plagnol,Kenneth J. Linton,Francis J. Smith,Neil Wilson,W.H. Irwin McLean,Colin S. Munro,Andrew P. South,Irene M. Leigh,Edel A. O’Toole,Anita Lundström,David P. Kelsell	59
8	Molecular Mechanistic Explanation for the Spectrum of Cholestatic Disease Caused by the S320F Variant of ABCB4 2013 ·Hepatology ·Edward J. Andress,Michael Nicolaou,Marta R. Romero,Sandhia Naik,Peter Dixon,Catherine Williamson,Kenneth J. Linton	28
9	Missense mutations and single nucleotide polymorphisms in ABCB11 impair bile salt export pump processing and function or disrupt pre-messenger RNA splicing # 2008 ·Hepatology ·Jane A. Byrne,Sandra Strautnieks,Gudrun Ihrke,(unknown),A. S. Knisely,Kenneth J. Linton,Giorgina Mieli‐Vergani,Richard J. Thompson	119
10	Cd36, a class B scavenger receptor, functions as a monomer to bind acetylated and oxidized low‐density lipoproteins 2007 ·Protein Science ·Catherine Martin,(unknown),C Wooding,Sarah Hoosdally,(unknown),Timothy J. Aitman,Daniel A.P. Gutmann,Paul S. Freemont,Bernadette Byrne,Kenneth J. Linton	33
11	Structure and function of ABC transporters: the ATP switch provides flexible control 2006 ·Pflügers Archiv - European Journal of Physiology ·Kenneth J. Linton,Christopher F. Higgins	168
12	Membrane phosphatidylserine distribution as a non-apoptotic signalling mechanism in lymphocytes 2005 ·Nature Cell Biology ·James I. Elliott,Annmarie Surprenant,Federica M. Marelli‐Berg,Joanne C. Cooper,Robin L. Cassady-Cain,C Wooding,Kenneth J. Linton,Denis R. Alexander,Christopher F. Higgins	194
13	A CD36 nonsense mutation associated with insulin resistance and familial type 2 diabetes 2004 ·Human Mutation ·Frédéric Leprêtre,Francis Vasseur,Martine Vaxillaire,Philipp E. Scherer,(unknown),Kenneth J. Linton,Timothy J. Aitman,Philippe Froguel	56
14	The Topography of Transmembrane Segment Six Is Altered during the Catalytic Cycle of P-glycoprotein 2004 ·Journal of Biological Chemistry ·Alice J. Rothnie,Janet Storm,(unknown),Kenneth J. Linton,Ian D. Kerr,Richard Callaghan	51
15	The ATP switch model for ABC transportersbreakdown → 2004 ·Nature Structural & Molecular Biology ·Christopher F. Higgins,Kenneth J. Linton	589
16	Communication between the Nucleotide Binding Domains of P-Glycoprotein Occurs via Conformational Changes that Involve Residue 508 2003 ·Biochemistry ·(unknown),Janet Storm,Alice J. Rothnie,Andrew M. Taylor,Kenneth J. Linton,Ian D. Kerr,Richard Callaghan	10
17	P-glycoprotein misfolds in Escherichia coli : evidence against alternating-topology models of the transport cycle 2002 ·Molecular Membrane Biology ·Kenneth J. Linton,Christopher F. Higgins	15
18	The human bile salt export pump: Characterization of substrate specificity and identification of inhibitors 2002 ·Gastroenterology ·Jane A. Byrne,Sandra Strautnieks,Giorgina Mieli‐Vergani,Christopher F. Higgins,Kenneth J. Linton,Richard J. Thompson	230
19	The Escherichia coli ATP‐binding cassette (ABC) proteins 1998 ·Molecular Microbiology ·Kenneth J. Linton,Christopher F. Higgins	355
20	Structure of the multidrug resistance P-glycoprotein 1997 ·Seminars in Cancer Biology ·Christopher F. Higgins,Richard Callaghan,Kenneth J. Linton,Mark F. Rosenberg,Robert C. Ford	93

About Kenneth J. Linton

Kenneth J. Linton is a scholar working on Oncology, Molecular Medicine and Pharmaceutical Science, having authored 46 papers that have together received 3.5k indexed citations. Recurring topics across this work include Drug Transport and Resistance Mechanisms (31 papers), HIV/AIDS drug development and treatment (9 papers) and Pediatric Hepatobiliary Diseases and Treatments (8 papers). The work is most often cited by research in Oncology (1.9k citations), Molecular Medicine (227 citations) and Physiology (105 citations). Kenneth J. Linton has collaborated with scholars based in United Kingdom, United States and Italy. Frequent co-authors include Christopher F. Higgins, Christopher F. Higgins, C Wooding, Joseph K. Zolnerciks, Edward J. Andress, Marco Falasca, Richard J. Thompson, Jane A. Byrne, Sandra Strautnieks and Giorgina Mieli‐Vergani. Their work appears in journals such as Journal of Biological Chemistry, Nature Communications and Gastroenterology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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