Christopher F. Higgins

26.7k total citations · 7 hit papers
166 papers, 22.1k citations indexed

About

Christopher F. Higgins is a scholar working on Molecular Biology, Genetics and Oncology. According to data from OpenAlex, Christopher F. Higgins has authored 166 papers receiving a total of 22.1k indexed citations (citations by other indexed papers that have themselves been cited), including 109 papers in Molecular Biology, 66 papers in Genetics and 64 papers in Oncology. Recurrent topics in Christopher F. Higgins's work include Bacterial Genetics and Biotechnology (62 papers), Drug Transport and Resistance Mechanisms (59 papers) and RNA and protein synthesis mechanisms (37 papers). Christopher F. Higgins is often cited by papers focused on Bacterial Genetics and Biotechnology (62 papers), Drug Transport and Resistance Mechanisms (59 papers) and RNA and protein synthesis mechanisms (37 papers). Christopher F. Higgins collaborates with scholars based in United Kingdom, United States and India. Christopher F. Higgins's co-authors include Kenneth J. Linton, Charles J. Dorman, Richard Callaghan, Ian R. Booth, C. S. J. Hulton, Stephen C. Hyde, Béatrice Py, Stephen R. Pearce, Noel H. Smith and Deborah R. Gill and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Christopher F. Higgins

165 papers receiving 21.5k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

ABC Transporters: From Microorganisms to Man

1992 3.3k citations Christopher F. Higgins profile →
Structural model of ATP-binding proteing associated with cystic fibrosis, multidrug resistance and bacterial transport

1990 957 citations Stephen C. Hyde, Stephen R. Pearce et al. Nature profile →
Multiple molecular mechanisms for multidrug resistance transporters

2007 708 citations Christopher F. Higgins Nature profile →
A physiological role for DNA supercoiling in the osmotic regulation of gene expression in S. typhimurium and E. coli

1988 609 citations Christopher F. Higgins, Charles J. Dorman et al. Cell profile →
The ATP switch model for ABC transporters

2004 589 citations Christopher F. Higgins et al. profile →
Volume-regulated chloride channels associated with the human multidrug-resistance P-glycoprotein

1992 492 citations Miguel A. Valverde, Mario Dı́az et al. Nature profile →
Repetitive extragenic palindromic sequences: A major component of the bacterial genome

1984 461 citations Christopher F. Higgins et al. Cell profile →

Peers

Countries citing papers authored by Christopher F. Higgins

Since Specialization

Citations

This map shows the geographic impact of Christopher F. Higgins's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christopher F. Higgins with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christopher F. Higgins more than expected).

Fields of papers citing papers by Christopher F. Higgins

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christopher F. Higgins. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christopher F. Higgins. The network helps show where Christopher F. Higgins may publish in the future.

Co-authorship network of co-authors of Christopher F. Higgins

This figure shows the co-authorship network connecting the top 25 collaborators of Christopher F. Higgins. A scholar is included among the top collaborators of Christopher F. Higgins based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Christopher F. Higgins. Christopher F. Higgins is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	ClC-3 expression enhances etoposide resistance by increasing acidification of the late endocytic compartment 2007 ·Molecular Cancer Therapeutics ·Karsten H. Weylandt, (unknown), (unknown), Joanna S. Amey, David Carmena, Bertram Wiedenmann, Christopher F. Higgins, Alessandro Sardini	51
2	Ability to Acquire Drug Resistance Arises Early during the Tumorigenesis Process 2007 ·Cancer Research ·Ernesto Yagüe, Ana Arance, (unknown), Michael J. O’Hare, Parmjit Jat, Caroline Mackie Ogilvie, Ian R. Hart, Christopher F. Higgins, Selina Raguz	53
3	Regulatory T Cells Are Resistant to Apoptosis via TCR but Not P2X7 2007 ·The Journal of Immunology ·Simon Taylor, Denis R. Alexander, Joanne C. Cooper, Christopher F. Higgins, James I. Elliott	36
4	Expression of RPIP9 (Rap2 interacting protein 9) is activated in breast carcinoma and correlates with a poor prognosis 2005 ·International Journal of Cancer ·Selina Raguz, Manuela Tamburo De Bella, Martin J. Slade, Christopher F. Higgins, R. Charles Coombes, Ernesto Yagüe	18
5	Cytoplasmic domains of the transporter associated with antigen processing and P-glycoprotein interact with subunits of the proteasome 2004 ·Molecular Immunology ·Gail S. Begley, Andrea R. Horvath, Jenny C. Taylor, Christopher F. Higgins	12
6	Two novel missense mutations in ABCA1 result in altered trafficking and cause severe autosomal recessive HDL deficiency 2004 ·Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease ·Christiane Albrecht, Kevin Baynes, Alessandro Sardini, Silke Schepelmann, Emily R. Eden, Simon Davies, Christopher F. Higgins, Michael Feher, James S. Owen, Anne K. Soutar	28
7	Three-dimensional Structures of the Mammalian Multidrug Resistance P-glycoprotein Demonstrate Major Conformational Changes in the Transmembrane Domains upon Nucleotide Binding 2003 ·Journal of Biological Chemistry ·Mark F. Rosenberg, (unknown), Richard Callaghan, Christopher F. Higgins, Robert C. Ford	165
8	Structural characterization of the N-terminal oligomerization domain of the bacterial chromatin-structuring protein, H-NS 2001 ·Journal of Molecular Biology ·Debora Renzoni, Diego Esposito, Mark Pfuhl, Jay C. D. Hinton, Christopher F. Higgins, Paul C. Driscoll, John E. Ladbury	32
9	Heterozygous MDR3 missense mutation associated with intrahepatic cholestasis of pregnancy 2000 ·Human Molecular Genetics ·Peter Dixon, (unknown), (unknown), (unknown), John C. Chambers, (unknown), J. Weaver, Catherine Nelson‐Piercy, Michael de Swiet, Gary Warnes, Ellen Roy Elias, Christopher F. Higgins, Desmond G. Johnston, Mark I. McCarthy, Catherine Williamson	5
10	Volume-regulated chloride channels associated with the human multidrug-resistance P-glycoprotein breakdown → 1992 ·Nature ·Miguel A. Valverde, Mario Dı́az, Francisco V. Sepúlveda, Deborah R. Gill, Stephen C. Hyde, Christopher F. Higgins	492
11	The chromatin-associated protein H-NS interacts with curved DNA to influence DNA topology and gene expression 1992 ·Cell ·Tom Owen‐Hughes, Graham D. Pavitt, Diógenes Santiago Santos, Julie M. Sidebotham, C. S. J. Hulton, Jay C. D. Hinton, Christopher F. Higgins	263
12	The oligopeptide transport system of Bacillus subtilis plays a role in the initiation of sporulation 1991 ·Molecular Microbiology ·M. Perego, Christopher F. Higgins, Stephen R. Pearce, Martin J. Gallagher, J A Hoch	279
13	ERIC sequences: a novel family of repetitive elements in the genomes of Escherichia coli, Salmonella typhimurium and other enterobacteria 1991 ·Molecular Microbiology ·C. S. J. Hulton, Christopher F. Higgins, Paul M. Sharp	460
14	Peptide transport and chemotaxis in Escherichia coli and Salmonella typhimurium: characterization of the dipeptide permease (Dpp) and the dipeptide‐binding protein 1991 ·Molecular Microbiology ·(unknown), Michael D. Manson, (unknown), Christopher F. Higgins	143
15	Structure and function of X-Pro dipeptide repeats in the TonB proteins of Salmonella typhimurium and Escherichia coli 1990 ·Journal of Molecular Biology ·Susan Brewer, Mark R. Tolley, I. P. Trayer, G. Barr, Charles J. Dorman, Kevin Hannavy, Christopher F. Higgins, James S. Evans, Barry A. Levine, Mark R. Wormald	91
16	Chromosome rearrangements induced by recombinant coliphage λpplacMu 1990 ·Gene ·Gordon Barr, Charles J. Dorman, (unknown), Christopher F. Higgins	2
17	Compartmentalization of the periplasm at cell division sites in Escherichia coli as shown by fluorescence photobleaching experiments 1989 ·Molecular Microbiology ·Michael Foley, (unknown), John J. Birmingham, William R. Cook, P. B. Garland, Christopher F. Higgins, Lawrence Rothfield	32
18	A novel, non‐invasive promoter probe vector: cloning of the osmoregulated proU promoter of Escherichia coli K12 1989 ·Molecular Microbiology ·(unknown), Douglas A. Stirling, C. S. J. Hulton, Ian R. Booth, Christopher F. Higgins, Gordon S.A.B. Stewart	46
19	A physiological role for DNA supercoiling in the osmotic regulation of gene expression in S. typhimurium and E. coli breakdown → 1988 ·Cell ·Christopher F. Higgins, Charles J. Dorman, Douglas A. Stirling, (unknown), Ian R. Booth, Gerhard May, Erhard Bremer	609
20	Books Received 1987 ·Heredity ·Christopher F. Higgins, (unknown), (unknown), (unknown)	1

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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