Christopher F. Higgins

26.7k total citations · 7 hit papers
166 papers, 22.1k citations indexed

About

Christopher F. Higgins is a scholar working on Molecular Biology, Genetics and Oncology. According to data from OpenAlex, Christopher F. Higgins has authored 166 papers receiving a total of 22.1k indexed citations (citations by other indexed papers that have themselves been cited), including 109 papers in Molecular Biology, 66 papers in Genetics and 64 papers in Oncology. Recurrent topics in Christopher F. Higgins's work include Bacterial Genetics and Biotechnology (62 papers), Drug Transport and Resistance Mechanisms (59 papers) and RNA and protein synthesis mechanisms (37 papers). Christopher F. Higgins is often cited by papers focused on Bacterial Genetics and Biotechnology (62 papers), Drug Transport and Resistance Mechanisms (59 papers) and RNA and protein synthesis mechanisms (37 papers). Christopher F. Higgins collaborates with scholars based in United Kingdom, United States and India. Christopher F. Higgins's co-authors include Kenneth J. Linton, Charles J. Dorman, Richard Callaghan, Ian R. Booth, C. S. J. Hulton, Stephen C. Hyde, Béatrice Py, Stephen R. Pearce, Noel H. Smith and Deborah R. Gill and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Christopher F. Higgins

165 papers receiving 21.5k citations

Hit Papers

ABC Transporters: From Microorganisms to Man 1984 2026 1998 2012 1992 1990 2007 1988 2004 1000 2.0k 3.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. ABC Transporters: From Microorganisms to Man
    1992 3.3k citations Christopher F. Higgins profile →
  2. Structural model of ATP-binding proteing associated with cystic fibrosis, multidrug resistance and bacterial transport
    1990 957 citations Stephen C. Hyde, Stephen R. Pearce et al. Nature profile →
  3. Multiple molecular mechanisms for multidrug resistance transporters
    2007 708 citations Christopher F. Higgins Nature profile →
  4. A physiological role for DNA supercoiling in the osmotic regulation of gene expression in S. typhimurium and E. coli
    1988 609 citations Christopher F. Higgins, Charles J. Dorman et al. Cell profile →
  5. The ATP switch model for ABC transporters
    2004 589 citations Christopher F. Higgins et al. profile →
  6. Volume-regulated chloride channels associated with the human multidrug-resistance P-glycoprotein
    1992 492 citations Miguel A. Valverde, Mario Dı́az et al. Nature profile →
  7. Repetitive extragenic palindromic sequences: A major component of the bacterial genome
    1984 461 citations Christopher F. Higgins et al. Cell profile →

Peers

Christopher F. Higgins
Li‐Wei Hung United States
Arthur B. Pardee United States
Gary J. Kapral United States
Wim G. J. Hol United States
Christian R.H. Raetz United States
Arthur Kornberg United States
Arnold J. M. Driessen Netherlands
Jeffrey Vieira United States
Wil N. Konings Netherlands
Bert Poolman Netherlands
Li‐Wei Hung United States
Christopher F. Higgins
Citations per year, relative to Christopher F. Higgins Christopher F. Higgins (= 1×) peers Li‐Wei Hung

Countries citing papers authored by Christopher F. Higgins

Since Specialization
Citations

This map shows the geographic impact of Christopher F. Higgins's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christopher F. Higgins with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christopher F. Higgins more than expected).

Fields of papers citing papers by Christopher F. Higgins

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christopher F. Higgins. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christopher F. Higgins. The network helps show where Christopher F. Higgins may publish in the future.

Co-authorship network of co-authors of Christopher F. Higgins

This figure shows the co-authorship network connecting the top 25 collaborators of Christopher F. Higgins. A scholar is included among the top collaborators of Christopher F. Higgins based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Christopher F. Higgins. Christopher F. Higgins is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Weylandt, Karsten H., Joanna S. Amey, David Carmena, et al.. (2007). ClC-3 expression enhances etoposide resistance by increasing acidification of the late endocytic compartment. Molecular Cancer Therapeutics. 6(3). 979–986. 51 indexed citations
2.
Yagüe, Ernesto, Ana Arance, Michael J. O’Hare, et al.. (2007). Ability to Acquire Drug Resistance Arises Early during the Tumorigenesis Process. Cancer Research. 67(3). 1130–1137. 53 indexed citations
3.
Taylor, Simon, Denis R. Alexander, Joanne C. Cooper, Christopher F. Higgins, & James I. Elliott. (2007). Regulatory T Cells Are Resistant to Apoptosis via TCR but Not P2X7. The Journal of Immunology. 178(6). 3474–3482. 36 indexed citations
4.
Raguz, Selina, Manuela Tamburo De Bella, Martin J. Slade, et al.. (2005). Expression of RPIP9 (Rap2 interacting protein 9) is activated in breast carcinoma and correlates with a poor prognosis. International Journal of Cancer. 117(6). 934–941. 18 indexed citations
5.
Begley, Gail S., Andrea R. Horvath, Jenny C. Taylor, & Christopher F. Higgins. (2004). Cytoplasmic domains of the transporter associated with antigen processing and P-glycoprotein interact with subunits of the proteasome. Molecular Immunology. 42(1). 137–141. 12 indexed citations
6.
Albrecht, Christiane, Kevin Baynes, Alessandro Sardini, et al.. (2004). Two novel missense mutations in ABCA1 result in altered trafficking and cause severe autosomal recessive HDL deficiency. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1689(1). 47–57. 28 indexed citations
7.
8.
Renzoni, Debora, Diego Esposito, Mark Pfuhl, et al.. (2001). Structural characterization of the N-terminal oligomerization domain of the bacterial chromatin-structuring protein, H-NS. Journal of Molecular Biology. 306(5). 1127–1137. 32 indexed citations
9.
Dixon, Peter, John C. Chambers, J. Weaver, et al.. (2000). Heterozygous MDR3 missense mutation associated with intrahepatic cholestasis of pregnancy. Human Molecular Genetics. 9(8). 5 indexed citations
10.
Valverde, Miguel A., Mario Dı́az, Francisco V. Sepúlveda, et al.. (1992). Volume-regulated chloride channels associated with the human multidrug-resistance P-glycoprotein. Nature. 355(6363). 830–833. 492 indexed citations breakdown →
11.
Owen‐Hughes, Tom, Graham D. Pavitt, Diógenes Santiago Santos, et al.. (1992). The chromatin-associated protein H-NS interacts with curved DNA to influence DNA topology and gene expression. Cell. 71(2). 255–265. 263 indexed citations
12.
Perego, M., Christopher F. Higgins, Stephen R. Pearce, Martin J. Gallagher, & J A Hoch. (1991). The oligopeptide transport system of Bacillus subtilis plays a role in the initiation of sporulation. Molecular Microbiology. 5(1). 173–185. 279 indexed citations
13.
Hulton, C. S. J., Christopher F. Higgins, & Paul M. Sharp. (1991). ERIC sequences: a novel family of repetitive elements in the genomes of Escherichia coli, Salmonella typhimurium and other enterobacteria. Molecular Microbiology. 5(4). 825–834. 460 indexed citations
14.
15.
Brewer, Susan, Mark R. Tolley, I. P. Trayer, et al.. (1990). Structure and function of X-Pro dipeptide repeats in the TonB proteins of Salmonella typhimurium and Escherichia coli. Journal of Molecular Biology. 216(4). 883–895. 91 indexed citations
16.
Barr, Gordon, et al.. (1990). Chromosome rearrangements induced by recombinant coliphage λpplacMu. Gene. 94(1). 15–22. 2 indexed citations
17.
Foley, Michael, John J. Birmingham, William R. Cook, et al.. (1989). Compartmentalization of the periplasm at cell division sites in Escherichia coli as shown by fluorescence photobleaching experiments. Molecular Microbiology. 3(10). 1329–1336. 32 indexed citations
18.
Stirling, Douglas A., et al.. (1989). A novel, non‐invasive promoter probe vector: cloning of the osmoregulated proU promoter of Escherichia coli K12. Molecular Microbiology. 3(8). 1011–1023. 46 indexed citations
19.
Higgins, Christopher F., Charles J. Dorman, Douglas A. Stirling, et al.. (1988). A physiological role for DNA supercoiling in the osmotic regulation of gene expression in S. typhimurium and E. coli. Cell. 52(4). 569–584. 609 indexed citations breakdown →
20.
Higgins, Christopher F., et al.. (1987). Books Received. Heredity. 58(3). 479–480. 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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