Juan C. Sáez

18.8k total citations · 3 hit papers
222 papers, 15.3k citations indexed

About

Juan C. Sáez is a scholar working on Molecular Biology, Physiology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Juan C. Sáez has authored 222 papers receiving a total of 15.3k indexed citations (citations by other indexed papers that have themselves been cited), including 186 papers in Molecular Biology, 53 papers in Physiology and 30 papers in Cellular and Molecular Neuroscience. Recurrent topics in Juan C. Sáez's work include Connexins and lens biology (160 papers), Nicotinic Acetylcholine Receptors Study (63 papers) and Biochemical effects in animals (35 papers). Juan C. Sáez is often cited by papers focused on Connexins and lens biology (160 papers), Nicotinic Acetylcholine Receptors Study (63 papers) and Biochemical effects in animals (35 papers). Juan C. Sáez collaborates with scholars based in Chile, United States and France. Juan C. Sáez's co-authors include Michael V. L. Bennett, David C. Spray, Feliksas F. Bukauskas, Juan Orellana, Mauricio A. Retamal, Agustı́n D. Martı́nez, Elliot L. Hertzberg, Jorge E. Contreras, María C. Brañes and Viviana M. Berthoud and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Juan C. Sáez

213 papers receiving 15.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Plasma Membrane Channels Formed by Connexins: Their Regulation and Functions

2003 963 citations Juan C. Sáez, Viviana M. Berthoud et al. profile →
Gap junctions: New tools, new answers, new questions

1991 806 citations Michael V. L. Bennett, Juan C. Sáez et al. profile →
Hepatocyte gap junctions are permeable to the second messenger, inositol 1,4,5-trisphosphate, and to calcium ions.

1989 500 citations Juan C. Sáez, Michael V. L. Bennett et al. Proceedings of the National Academy of Sciences profile →

Peers

Countries citing papers authored by Juan C. Sáez

Since Specialization

Citations

This map shows the geographic impact of Juan C. Sáez's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Juan C. Sáez with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Juan C. Sáez more than expected).

Fields of papers citing papers by Juan C. Sáez

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Juan C. Sáez. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Juan C. Sáez. The network helps show where Juan C. Sáez may publish in the future.

Co-authorship network of co-authors of Juan C. Sáez

This figure shows the co-authorship network connecting the top 25 collaborators of Juan C. Sáez. A scholar is included among the top collaborators of Juan C. Sáez based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Juan C. Sáez. Juan C. Sáez is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Connexin and Pannexin Hemichannels: Broad‐Spectrum Players in Neuroinflammatory Signaling 2025 ·Journal of Neurochemistry ·Juan C. Sáez, (unknown), (unknown), Juan Orellana	0
2	The antiseizure medication valproate increases hemichannel activity found in brain cells, which could worsen disease outcomes 2024 ·Journal of Neurochemistry ·(unknown), Yorley Duarte, Álvaro O. Ardiles, Juan C. Sáez	1
3	Acute activation of hemichannels by ethanol leads to Ca2+-dependent gliotransmitter release in astrocytes 2024 ·Frontiers in Cell and Developmental Biology ·Gonzalo I. Gómez, (unknown), (unknown), (unknown), (unknown), (unknown), Juan C. Sáez, Mauricio A. Retamal, Maximiliano Rovegno, Fernando C. Ortíz, Juan Orellana	1
4	Pharmacology of boldine: summary of the field and update on recent advances 2024 ·Frontiers in Pharmacology ·Juan C. Sáez, Justin C. Burrell, Catherine M. Cahill, D. Kacy Cullen, Lakshmi A. Devi, Ryan J. Gilbert, Zachary Graham, (unknown), Leif A. Havton, Ravi Iyengar, Rajesh Khanna, Edmund F. Palermo, Mustafa M. Siddiq, Carlos A. Toro, (unknown), Wei Zhao, Christopher Cardozo	6
5	Cx43 hemichannels and panx1 channels contribute to ethanol-induced astrocyte dysfunction and damage 2024 ·Biological Research ·Gonzalo I. Gómez, (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), Juan C. Sáez, Fernando C. Ortíz, Juan Orellana	8
6	Lack of canonical activities of connexins in highly aggressive human prostate cancer cells 2024 ·Biological Research ·(unknown), (unknown), (unknown), Lorena Azócar, (unknown), (unknown), (unknown), (unknown), Paula Sotomayor, Jorge Cancino, Bredford Kerr, (unknown), Mauricio A. Retamal, Juan C. Sáez, Alejandro Godoy	3
7	Ca²⁺permeation through C-terminal cleaved, but not full-length human Pannexin1 hemichannels, mediates cell death 2024 ·Proceedings of the National Academy of Sciences ·Magdiel Salgado, Valeria Márquez‐Miranda, Luciano Ferrada, (unknown), (unknown), Fernando D. González‐Nilo, Álvaro O. Ardiles, Juan C. Sáez	8
8	Inhibition of astroglial hemichannels prevents synaptic transmission decline during spreading depression 2024 ·Biological Research ·Juan E. Tichauer, Matías Lira, Waldo Cerpa, Juan Orellana, Juan C. Sáez, Maximiliano Rovegno	3
9	Boldine modulates glial transcription and functional recovery in a murine model of contusion spinal cord injury 2023 ·Frontiers in Cellular Neuroscience ·Carlos A. Toro, (unknown), Jens Hansen, Mustafa M. Siddiq, (unknown), Wei Zhao, Zachary Graham, Juan C. Sáez, Ravi Iyengar, Christopher Cardozo	12
10	Skeletal Muscle Atrophy Induced by Diabetes Is Mediated by Non-Selective Channels and Prevented by Boldine 2023 ·Biomolecules ·A. Luis, (unknown), (unknown), (unknown), Mario Castillo–Ruiz, Victoria Velarde, Magdiel Salgado, Juan C. Sáez	10
11	TNF-α Plus IL-1β Induces Opposite Regulation of Cx43 Hemichannels and Gap Junctions in Mesangial Cells through a RhoA/ROCK-Dependent Pathway 2022 ·International Journal of Molecular Sciences ·Claudia Lucero, (unknown), (unknown), (unknown), (unknown), Paola Fernández, Juan Orellana, Victoria Velarde, Juan C. Sáez, Gonzalo I. Gómez	7
12	Retrograde and Anterograde Transport of Lat-Vesicles during the Immunological Synapse Formation: Defining the Finely-Tuned Mechanism 2021 ·Cells ·Juan C. Sáez, Stéphanie Dogniaux, Massiullah Shafaq‐Zadah, Ludger Johannes, Claire Hivroz, Andrés E. Zucchetti	4
13	Blockade of Hemichannels Normalizes the Differentiation Fate of Myoblasts and Features of Skeletal Muscles from Dysferlin-Deficient Mice 2020 ·International Journal of Molecular Sciences ·A. Luis, (unknown), (unknown), Mario Castillo–Ruiz, Rosalba Escamilla, María C. Brañes, Juan C. Sáez	14
14	Confirmation of Connexin45 Underlying Weak Gap Junctional Intercellular Coupling in HeLa Cells 2020 ·Biomolecules ·Eun Ju Choi, Nicolás Palacios‐Prado, Juan C. Sáez, Jinu Lee	17
15	Permeation of Molecules through Astroglial Connexin 43 Hemichannels Is Modulated by Cytokines with Parameters Depending on the Permeant Species 2020 ·International Journal of Molecular Sciences ·Juan C. Sáez, Aníbal A. Vargas, Diego E. Hernández, Fernando C. Ortíz, Christian Giaume, Juan Orellana	19
16	Role of calcium permeable channels in dendritic cell migration 2018 ·Current Opinion in Immunology ·Pablo J. Sáez, Juan C. Sáez, Ana‐Maria Lennon‐Duménil, Pablo Vargas	19
17	ATP promotes the fast migration of dendritic cells through the activity of pannexin 1 channels and P2X ₇ receptors 2017 ·Science Signaling ·Pablo J. Sáez, Pablo Vargas, Kenji F. Shoji, Paloma A. Harcha, Ana‐Maria Lennon‐Duménil, Juan C. Sáez	130
18	De novo expression of connexin hemichannels in denervated fast skeletal muscles leads to atrophy 2013 ·Proceedings of the National Academy of Sciences ·A. Luis, Bruno A. Cisterna, Carlos Puebla, Marina Frank, Xavier F. Figueroa, Christopher Cardozo, Klaus Willecke, Ramón Latorre, Juan C. Sáez	96
19	Gap Junction Intercellular Communication Mediated by Connexin43 in Astrocytes Is Essential for Their Resistance to Oxidative Stress 2013 ·Journal of Biological Chemistry ·Hoa Le, Wun Chey Sin, (unknown), John F. Bechberger, José Luis Vega, Xu Guo, Juan C. Sáez, Christian C. Naus	93
20	Modulation of gap junction channels and hemichannels by growth factors 2012 ·Molecular BioSystems ·Kurt A. Schalper, Manuel A. Riquelme, María C. Brañes, Agustı́n D. Martı́nez, José Luis Vega, Viviana M. Berthoud, Michael V. L. Bennett, Juan C. Sáez	28

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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