Jonathan L. E. Dean

4.1k citations

41 papers · 3.5k indexed · h-index 30

Impact in

Cancer Research top 2%
- NF-κB Signaling Pathways
Immunology top 2%
- Immune Response and Inflammation

Papers in

Biochemistry 6
- Amino Acid Enzymes and Metabolism 6
Cancer Research 10
- NF-κB Signaling Pathways 7

Co-authors: Jeremy Saklatvala Andrew R. Clark Matthew Brook Gareth Sully Kamal R Mahtani Lesley Rawlinson Robin Wait S J Sarsfield
Journals: Journal of Biological Chemistry (6 papers)Biochemical Journal (5 papers)Molecular and Cellular Biology (5 papers)FEBS Letters (3 papers)The Journal of Immunology (3 papers)
Partner nations: United Kingdom United States Ireland

In The Last Decade

Jonathan L. E. Dean

41 papers receiving 3.5k citations

Peers

Countries citing papers authored by Jonathan L. E. Dean

Since Specialization

Citations

This map shows the geographic impact of Jonathan L. E. Dean's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jonathan L. E. Dean with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jonathan L. E. Dean more than expected).

Fields of papers citing papers by Jonathan L. E. Dean

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jonathan L. E. Dean. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jonathan L. E. Dean. The network helps show where Jonathan L. E. Dean may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Jonathan L. E. Dean, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jonathan L. E. Dean Line = papers co-authored together Jonathan L. E. Dean links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	HSP25 Vaccination Attenuates Atherogenesis via Upregulation of LDLR Expression, Lowering of PCSK9 Levels and Curbing of Inflammation Arteriosclerosis Thrombosis and Vascular Biology ·Yong‐Xiang Chen, Chunhua Shi, Jingti Deng, Catherine Diao, Kejal Chavda, Guido Lozada Prado, Marwa Missaoui, Р. И. Корнейков, Francesco B. Dileo, Ayinuer Adijiang, Annegret Ulke‐Lemée, Brenig Llwyd Gwilym, 윤도진, Binting Xu, Zarah Batulan, Jonathan L. E. Dean, F. Daniel Ramirez, Jingwen Liu, William T. Gerthoffer, Edward R. O’Brien	2021	14
2	Tryptophan-Mediated Interactions between Tristetraprolin and the CNOT9 Subunit Are Required for CCR4-NOT Deadenylase Complex Recruitment Journal of Molecular Biology ·William Kessier, Jasper, P. Mahajan, Manjunath Cn, Oleg Fedorov, Francesco P. Marchese, Anna Aubareda, R. Chalk, S. Picaud, Claire Strain‐Damerell, P. Filippakopoulos, O. Gileadi, Andrew R. Clark, Wyatt W. Yue, N. Burgess-Brown, Jonathan L. E. Dean	2017	35
3	Gain-of-Function Mutation of Tristetraprolin Impairs Negative Feedback Control of Macrophages In Vitro yet Has Overwhelmingly Anti-Inflammatory Consequences In Vivo Molecular and Cellular Biology ·John D. O’Neil, Ewan A. Ross, Michael Ridley, J. García Tolsá, 進保星野, Dalya R. Soond, Thomas E. Crowley, Aysegul Ciftci Sandikci, Jonathan L. E. Dean, Tim Smallie, Christopher D. Buckley, Andrew R. Clark	2017	41
4	Treatment of inflammatory arthritis via targeting of tristetraprolin, a master regulator of pro-inflammatory gene expression Annals of the Rheumatic Diseases ·Ewan A. Ross, Amy J. Naylor, John D. O’Neil, T Crowley, Michael Ridley, Jenny Crowe, Timothy Smallie, 進保星野, Jason D. Turner, Lucy V. Norling, Salina Dominguez, Harris Perlman, Nicole M. Verrills, George Kollias, Michael P. Vitek, Andrew Filer, Christopher D. Buckley, Jonathan L. E. Dean, Andrew R. Clark	2016	62
5	TNFR2 increases the sensitivity of ligand-induced activation of the p38 MAPK and NF-κB pathways and signals TRAF2 protein degradation in macrophages Cellular Signalling ·Oksana Mačėnaitė, Emily M. Schmidt, Fiona E. McCann, Marc Feldmann, Richard Williams, A. Allart Stoop, Jonathan L. E. Dean	2014	31
6	Selective Tumor Necrosis Factor Receptor I Blockade Is Antiinflammatory and Reveals Immunoregulatory Role of Tumor Necrosis Factor Receptor II in Collagen‐Induced Arthritis Arthritis & Rheumatology ·Fiona E. McCann, Dany Perocheau, Oksana Mačėnaitė, Katrina Blazek, Marie Davies, Marc Feldmann, Jonathan L. E. Dean, A. Allart Stoop, Richard Williams	2014	97
7	MAPKAP Kinase 2 Blocks Tristetraprolin-directed mRNA Decay by Inhibiting CAF1 Deadenylase Recruitment Journal of Biological Chemistry ·Francesco P. Marchese, Anna Aubareda, Sarah M. Kamil, Jeremy Saklatvala, Andrew R. Clark, Jonathan L. E. Dean	2010	132
8	The p38 MAPK pathway inhibits tristetraprolin‐directed decay of interleukin‐10 and pro‐inflammatory mediator mRNAs in murine macrophages FEBS Letters ·Sarah M. Kamil, Francesco P. Marchese, Edward Hitti, Anna Aubareda, Lesley Rawlinson, Matthias Gaestel, Perry J. Blackshear, Andrew R. Clark, Jeremy Saklatvala, Jonathan L. E. Dean	2009	80
9	NF-κB Suppression by the Deubiquitinating Enzyme Cezanne Journal of Biological Chemistry ·Karine Enesa, Mustafa Zakkar, Hera Chaudhury, Le Anh Luong, Lesley Rawlinson, Justin C. Mason, Dorian O. Haskard, Jonathan L. E. Dean, Paul C. Evans	2008	178
10	Hydrogen Peroxide Prolongs Nuclear Localization of NF-κB in Activated Cells by Suppressing Negative Regulatory Mechanisms Journal of Biological Chemistry ·Karine Enesa, Kazuhiro Ito, Le Anh Luong, Samuel Marcushamer, Chengshan Wang, Yasuo To, Jonathan L. E. Dean, Dorian O. Haskard, 郭瑜琳, Ian M. Adcock, Paul C. Evans	2008	52
11	The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathway-mediated mRNA stabilisation Cellular Signalling ·Jonathan L. E. Dean, Gareth Sully, Andrew R. Clark, Jeremy Saklatvala	2004	267
12	p38 Mitogen-activated Protein Kinase Stabilizes mRNAs That Contain Cyclooxygenase-2 and Tumor Necrosis Factor AU-rich Elements by Inhibiting Deadenylation Journal of Biological Chemistry ·Jonathan L. E. Dean, S J Sarsfield, Karolina Wawrocka, Jeremy Saklatvala	2003	89
13	Post‐transcriptional regulation of gene expression by mitogen‐activated protein kinase p38 FEBS Letters ·Andrew R. Clark, Jonathan L. E. Dean, Jeremy Saklatvala	2003	171
14	The 3′ Untranslated Region of Tumor Necrosis Factor Alpha mRNA Is a Target of the mRNA-Stabilizing Factor HuR Molecular and Cellular Biology ·Jonathan L. E. Dean, Robin Wait, Kamal R Mahtani, Gareth Sully, Andrew R. Clark, Jeremy Saklatvala	2001	253
15	Mitogen-Activated Protein Kinase p38 Controls the Expression and Posttranslational Modification of Tristetraprolin, a Regulator of Tumor Necrosis Factor Alpha mRNA Stability Molecular and Cellular Biology ·Kamal R Mahtani, Matthew Brook, Jonathan L. E. Dean, Gareth Sully, Jeremy Saklatvala, Andrew R. Clark	2001	390
16	p38 Mitogen-activated Protein Kinase Regulates Cyclooxygenase-2 mRNA Stability and Transcription in Lipopolysaccharide-treated Human Monocytes Journal of Biological Chemistry ·Jonathan L. E. Dean, Matthew Brook, Andrew R. Clark, Jeremy Saklatvala	1999	461
17	Chemical rescue of the catalytically disabled clostridial glutamate dehydrogenase mutant D165S by fluoride ion Biochemical Journal ·Estomish M S Kombe, Jonathan L. E. Dean, Stephen R. Martin, Paul C. Engel	1999	9
18	Alteration of the quaternary structure of glutamate dehydrogenase from Clostridium symbiosum by a single mutation distant from the subunit interfaces European Biophysics Journal ·Jonathan L. E. Dean, Helmut Cölfen, Stephen E. Harding, David W. Rice, Paul C. Engel	1997	7
19	The changed pattern of substrate specificity in the K89L mutant of glutamate dehydrogenase of Clostridium symbiosum Biochemical Society Transactions ·Xingguo Wang, Jonathan L. E. Dean, Paul C. Engel, Patrick J. Baker, K.L. Britton, Timothy J. Stillman, David W. Rice	1994	1
20	Crystallization of the NADP+-dependent Glutamate Dehydrogenase from Escherichia coli Journal of Molecular Biology ·Sashi P. Singh, P.J. Rizkallah, Teresa K. Attwood, John C. Wootton, Michael J. McPherson, A.C.T. North, J. A. Grunt, I. Sarath B. Abeysinghe, Patrick J. Baker, Jonathan L. E. Dean, Paul C. Engel, Timothy J. Stillman, David W. Rice	1993	10

About Jonathan L. E. Dean

Jonathan L. E. Dean is a scholar working on Biochemistry, Cancer Research, Molecular Biology, Immunology and Pharmacology, having authored 41 papers that have together received 3.5k indexed citations. Recurring topics across this work include RNA Research and Splicing (13 papers), Immune Response and Inflammation (8 papers), NF-κB Signaling Pathways (7 papers), Cytokine Signaling Pathways and Interactions (7 papers), Amino Acid Enzymes and Metabolism (6 papers), RNA and protein synthesis mechanisms (6 papers), Enzyme Structure and Function (6 papers) and Melanoma and MAPK Pathways (5 papers). The work is most often cited by research in Cancer Research (844 citations), Immunology (996 citations), Molecular Biology (2.2k citations), Oncology (653 citations) and Pharmacology (371 citations). Jonathan L. E. Dean has collaborated with scholars based in United Kingdom, United States and Ireland. Frequent co-authors include Jeremy Saklatvala, Andrew R. Clark, Matthew Brook, Gareth Sully, Kamal R Mahtani, Lesley Rawlinson, Robin Wait, S J Sarsfield, Anna Aubareda and Francesco P. Marchese. Their work appears in journals such as Journal of Biological Chemistry, Biochemical Journal, Molecular and Cellular Biology, FEBS Letters and The Journal of Immunology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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