John C. Wootton

14.5k citations

83 papers · 10.9k indexed · 7 hit papers · h-index 42

Molecular Biology top 1%
Public Health, Environmental and Occupational Health top 0.5%
Genetics top 1%
Parasitology top 0.2%
Plant Science top 2%

Co-authors: Scott Federhen Stephen F. Altschul Mark S. Boguski Charles E. Lawrence Andrew F. Neuwald Jun S. Liu Martin Drummond Roland A. Cooper
Topics: Amino Acid Enzymes and Metabolism (18 papers)Genomics and Phylogenetic Studies (13 papers)RNA and protein synthesis mechanisms (13 papers)
Cited by: Parasitology Molecular Biology Public Health, Environmental and Occupational Health
Journals: Nature Science Cell
Partner nations: United Kingdom United States Japan

In The Last Decade

John C. Wootton

83 papers receiving 10.5k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Detecting Subtle Sequence Signals: a Gibbs Sampling Strategy for Multiple Alignment

1993 1.3k citations Stephen F. Altschul, Mark S. Boguski et al. Science profile →
Mutations in the P. falciparum Digestive Vacuole Transmembrane Protein PfCRT and Evidence for Their Role in Chloroquine Resistance

2000 1.1k citations David A. Fidock, Takashi Nomura et al. profile →
Protein database searches using compositionally adjusted substitution matrices

2005 827 citations Stephen F. Altschul, John C. Wootton et al. profile →
Issues in searching molecular sequence databases

1994 648 citations Stephen F. Altschul, Mark S. Boguski et al. Nature Genetics profile →
[33] Analysis of compositionally biased regions in sequence databases

1996 614 citations John C. Wootton, Scott Federhen Methods in enzymology on CD-ROM/Methods in enzymology profile →
Statistics of local complexity in amino acid sequences and sequence databases

1993 562 citations John C. Wootton, Scott Federhen profile →
Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum

2002 551 citations John C. Wootton, Roland A. Cooper et al. Nature profile →

Peers

Countries citing papers authored by John C. Wootton

Since Specialization

Citations

This map shows the geographic impact of John C. Wootton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John C. Wootton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John C. Wootton more than expected).

Fields of papers citing papers by John C. Wootton

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John C. Wootton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John C. Wootton. The network helps show where John C. Wootton may publish in the future.

Co-authorship network of co-authors of John C. Wootton

This figure shows the co-authorship network connecting the top 25 collaborators of John C. Wootton. A scholar is included among the top collaborators of John C. Wootton based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with John C. Wootton. John C. Wootton is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Virulence differences in Toxoplasma mediated by amplification of a family of polymorphic pseudokinases 2011 ·Proceedings of the National Academy of Sciences ·Michael S. Behnke,Asis Khan,John C. Wootton,J. P. Dubey,Keliang Tang,L. David Sibley	174
2	The Construction and Use of Log-Odds Substitution Scores for Multiple Sequence Alignment 2010 ·PLoS Computational Biology ·Stephen F. Altschul,John C. Wootton,Elena Zaslavsky,Yi‐Kuo Yu	51
3	A Secreted Serine-Threonine Kinase Determines Virulence in the Eukaryotic Pathogen Toxoplasma gondii 2006 ·Science ·S. Taylor,Antonio Barragán,Chunlei Su,Blima Fux,Sarah J. Fentress,Keliang Tang,Wandy L. Beatty,Hiba El Hajj,Maria Jerome,Michael S. Behnke,Michael W. White,John C. Wootton,L. David Sibley	411
4	Composite genome map and recombination parameters derived from three archetypal lineages of Toxoplasma gondii 2005 ·Nucleic Acids Research ·Asis Khan,S. Taylor,Chunlei Su,Aaron J. Mackey,Jon P. Boyle,Robert H. Cole,(unknown),Keliang Tang,Ian T. Paulsen,Matthew Berriman,John C. Boothroyd,E. R. Pfefferkorn,J. P. Dubey,James W. Ajioka,David S. Roos,John C. Wootton,L. David Sibley	127
5	Algorithms for computing lengths of chains in integral partition lattices 2002 ·Theoretical Computer Science ·(unknown),John C. Wootton	3
6	Evidence for Different Mechanisms of Chloroquine Resistance in 2PlasmodiumSpecies That Cause Human Malaria 2001 ·The Journal of Infectious Diseases ·Takashi Nomura,Jane M. Carlton,J. Kevin Baird,Hernando A. del Portillo,David J. Fryauff,Dharmendar Rathore,David A. Fidock,Xin Su,William E. Collins,Thomas F. McCutchan,John C. Wootton,Thomas E. Wellems	138
7	Selenocysteine-Containing Thioredoxin Reductase in C. elegans 1999 ·Biochemical and Biophysical Research Communications ·Vadim N. Gladyshev,Michael Krause,(unknown),Konstantin V. Korotkov,Gregory V. Kryukov,Qi-An Sun,(unknown),John C. Wootton,Dolph L. Hatfield	75
8	Unusual insertion element polymorphisms in the promoter and terminator regions of the mucAB-like genes of R471a and R446b 1998 ·Mutation research. Fundamental and molecular mechanisms of mutagenesis ·Olga I. Kulaeva,Eugene V. Koonin,John C. Wootton,(unknown),Roger Woodgate	27
9	P. falciparum CG2, Linked to Chloroquine Resistance, Does Not Resemble Na+/H+ Exchangers 1998 ·Cell ·Thomas E. Wellems,John C. Wootton,Hisashi Fujioka,Xin‐zhuan Su,Roland A. Cooper,Dror I. Baruch,David A. Fidock	20
10	[33] Analysis of compositionally biased regions in sequence databasesbreakdown → 1996 ·Methods in enzymology on CD-ROM/Methods in enzymology ·John C. Wootton,Scott Federhen	614
11	Molecular cloning of Drosophila TFIID subunits 1994 ·Nature ·Tetsuro Kokubo,Da‐Wei Gong,John C. Wootton,Masami Horikoshi,Robert G. Roeder,Yoshihiro Nakatani	103
12	Issues in searching molecular sequence databasesbreakdown → 1994 ·Nature Genetics ·Stephen F. Altschul,Mark S. Boguski,Warren Gish,John C. Wootton	648
13	A 127 kDa component of a UV-damaged DNA-binding complex, which is defective in some xeroderma pigmentosum group E patients, is homologous to a slime mold protein 1993 ·Nucleic Acids Research ·Masashi Takao,Marija Abramić,Malcolm Moos,(unknown),John C. Wootton,Mary P. McLenigan,C. Elizabeth Shaaban,Miroslava Protić	89
14	Crystallization of the NADP+-dependent Glutamate Dehydrogenase from Escherichia coli 1993 ·Journal of Molecular Biology ·(unknown),P.J. Rizkallah,Teresa K. Attwood,John C. Wootton,Michael J. McPherson,A.C.T. North,(unknown),I. Sarath B. Abeysinghe,Patrick J. Baker,Jonathan L. E. Dean,Paul C. Engel,Timothy J. Stillman,David W. Rice	10
15	TPR Proteins as Essential Components of the Yeast Cell Cycle 1991 ·Cold Spring Harbor Symposia on Quantitative Biology ·R Sikorski,William A. Michaud,John C. Wootton,Mark S. Boguski,Carla J. Connelly,Philip Hieter	68
16	Enzymes depending on the pterin molybdenum cofactor: sequence families, spectroscopic properties of molybdenum and possible cofactor-binding domains 1991 ·Biochimica et Biophysica Acta (BBA) - Bioenergetics ·John C. Wootton,(unknown),J. Mark Cock,(unknown),Julian F. Burke,Wendy A. Doyle,Robert C. Bray	141
17	Nucleotide sequence, organisation and structural analysis of the products of genes in the nirB–cysG region of the Escherichia coli K‐12 chromosome 1990 ·European Journal of Biochemistry ·Timothy C. Peakman,Joël Crouzet,(unknown),Stephen Busby,S. B. Mohan,Nerina Harborne,John C. Wootton,(unknown),Jeffrey A. Cole	117
18	DNA sequence analysis of artificially evolved ebg enzyme and ebg repressor genes. 1989 ·Genetics ·B G Hall,(unknown),John C. Wootton	35
19	Structural analysis of homologous repeated domains in α-actinin and spectrin 1989 ·International Journal of Biological Macromolecules ·Matt Davison,Michael D. Baron,David R. Critchley,John C. Wootton	63
20	Streptomyces griseus Streptomycin Phosphotransferase: Expression of Its Gene in Escherichia coli and Sequence Homology with Other Antibiotic Phosphotransferases and with Eukaryotic Protein Kinases 1989 ·Microbiology ·Chang‐Kweng Lim,Margaret C. M. Smith,(unknown),S. Baumberg,John C. Wootton	17

About John C. Wootton

John C. Wootton is a scholar working on Biochemistry, Microbiology and Molecular Medicine, having authored 83 papers that have together received 10.9k indexed citations. Recurring topics across this work include Amino Acid Enzymes and Metabolism (18 papers), Genomics and Phylogenetic Studies (13 papers) and RNA and protein synthesis mechanisms (13 papers). The work is most often cited by research in Parasitology (1.2k citations), Molecular Biology (6.0k citations) and Public Health, Environmental and Occupational Health (2.2k citations). John C. Wootton has collaborated with scholars based in United Kingdom, United States and Japan. Frequent co-authors include Scott Federhen, Stephen F. Altschul, Mark S. Boguski, Charles E. Lawrence, Andrew F. Neuwald, Jun S. Liu, Martin Drummond, Roland A. Cooper, Michael T. Ferdig and Warren Gish. Their work appears in journals such as Nature, Science and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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