Edward R. O’Brien

9.1k citations

150 papers · 6.1k · 1 hit paper · h-index 39

Impact in

Cardiology and Cardiovascular Medicine top 1%
- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
Immunology and Allergy top 1%
- Cell Adhesion Molecules Research

Papers in

Molecular Biology 64
- Heat shock proteins research 25
- Angiogenesis and VEGF in Cancer 16
Surgery 55
- Coronary Interventions and Diagnostics 43

Co-authors: Stephen M. Schwartz (2 shared papers)Denis deBlois (1 shared paper)Stephen M. Schwartz (9 shared papers)Marino Labinaz (38 shared papers)Benjamin Hibbert (34 shared papers)John B. Simpson (7 shared papers)Tomoaki Hinohara (6 shared papers)Douglas K. Stewart (5 shared papers)
Journals: Circulation (11 papers)Canadian Journal of Cardiology (8 papers)Arteriosclerosis Thrombosis and Vascular Biology (8 papers)Journal of the American College of Cardiology (7 papers)The FASEB Journal (5 papers)
Partner nations: Canada United States United Kingdom

In The Last Decade

Edward R. O’Brien

143 papers receiving 5.9k citations

Edward R. O’Brien's Hit Papers

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The Intima 1995 · 834 citations

Peers

Countries citing papers authored by Edward R. O’Brien

Since Specialization

Citations

This map shows the geographic impact of Edward R. O’Brien's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Edward R. O’Brien with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Edward R. O’Brien more than expected).

Fields of papers citing papers by Edward R. O’Brien

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Edward R. O’Brien. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Edward R. O’Brien. The network helps show where Edward R. O’Brien may publish in the future.

Co-authors

The 25 scholars most cited alongside Edward R. O’Brien, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Edward R. O’Brien Line = papers co-authored together Edward R. O’Brien links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 150 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	The Intima Circulation Research ·Stephen M. Schwartz, Denis deBlois, Edward R. O’Brien Hit paper breakdown →	1995	834
2	A Citywide Protocol for Primary PCI in ST-Segment Elevation Myocardial Infarction New England Journal of Medicine ·Michel R. Le May, Derek So, Richard Dionne, Chris Glover, Michael Froeschl, George A. Wells, Richard F. Davies, Heather L. Sherrard, Justin Maloney, Jean-François Marquis, Edward R. O’Brien, John Trickett, P. Poirier, Sheila C. Ryan, Andrew C.T. Ha, Phil Joseph, Marino Labinaz	2008	301
3	Proliferation in primary and restenotic coronary atherectomy tissue. Implications for antiproliferative therapy. Circulation Research ·Edward R. O’Brien, Charles E. Alpers, Douglas K. Stewart, Marina S. Ferguson, Nam T. Tran, David Gordon, Earl P. Benditt, Tomoaki Hinohara, John B. Simpson, Stephen M. Schwartz	1993	294
4	Detection of Chlamydia pneumoniae TWAR in Human Coronary Atherectomy Tissues The Journal of Infectious Diseases ·Lee Ann Campbell, Edward R. O’Brien, A Cappuccio, C.‐C. Jay Kuo, S.-p. Wang, David G. Stewart, Dorothy L. Patton, Peter K. Cummings, J. Thomas Grayston	1995	282
5	Point-of-care genetic testing for personalisation of antiplatelet treatment (RAPID GENE): a prospective, randomised, proof-of-concept trial The Lancet ·Jason D. Roberts, George A. Wells, Michel R. Le May, Marino Labinaz, Chris Glover, Michael Froeschl, Alexander Dick, Jean-François Marquis, Edward R. O’Brien, Sandro Cadaval Gonçalves, Irena Druce, Alexandre F.R. Stewart, Michael H. Gollob, Derek So	2012	276
6	Osteopontin is synthesized by macrophage, smooth muscle, and endothelial cells in primary and restenotic human coronary atherosclerotic plaques. Arteriosclerosis and Thrombosis A Journal of Vascular Biology ·Edward R. O’Brien, Michael R. Garvin, Douglas K. Stewart, Tomoaki Hinohara, John B. Simpson, Stephen M. Schwartz, Cecilia M. Giachelli	1994	275
7	Angiogenesis in human coronary atherosclerotic plaques. PubMed ·Edward R. O’Brien, Michael R. Garvin, R Dev, Douglas K. Stewart, Tomoaki Hinohara, John B. Simpson, Stephen M. Schwartz	1994	213
8	In vitro susceptibility of human vascular wall cells to infection with Chlamydia pneumoniae Journal of Clinical Microbiology ·K L Godzik, Edward R. O’Brien, S K Wang, C C Kuo	1995	162
9	Combined Angioplasty and Pharmacological Intervention Versus Thrombolysis Alone in Acute Myocardial Infarction (CAPITAL AMI Study) Journal of the American College of Cardiology ·Michel R. Le May, George A. Wells, Marino Labinaz, Richard F. Davies, Michèle Turek, Danielle Leddy, Justin Maloney, Tim McKibbin, Brendan Quinn, Rob Beanlands, Chris Glover, Jean-François Marquis, Edward R. O’Brien, William L. Williams, Lyall Higginson	2005	152
10	17β-Estradiol downregulates tissue angiotensin-converting enzyme and ANG II type 1 receptor in female rats American Journal of Physiology-Regulatory, Integrative and Comparative Physiology ·Stephanie Dean, Junhui Tan, Edward R. O’Brien, Frans H. H. Leenen	2004	118
11	The Evolution of Coronary Stents: A Brief Review Canadian Journal of Cardiology ·Trevor Simard, Benjamin Hibbert, F. Daniel Ramirez, Michael Froeschl, Yong-Xiang Chen, Edward R. O’Brien	2013	112
12	Gene Dosage of the Common Variant 9p21 Predicts Severity of Coronary Artery Disease Journal of the American College of Cardiology ·Sonny Dandona, Alexandre F.R. Stewart, Li Chen, Kathryn Williams, Derek So, Edward R. O’Brien, Christopher Glover, Michel Lemay, Olivia Assogba, Lan Vo, Yan Qing Wang, Marino Labinaz, George A. Wells, Ruth McPherson, Robert Roberts	2010	108
13	Neuroimmune Guidance Cue Semaphorin 3E Is Expressed in Atherosclerotic Plaques and Regulates Macrophage Retention Arteriosclerosis Thrombosis and Vascular Biology ·Amarylis Wanschel, Tara Seibert, Bernd Hewing, Bhama Ramkhelawon, Tathagat Dutta Ray, Janine M. van Gils, Katey J. Rayner, Jonathan E. Feig, Edward R. O’Brien, Edward A. Fisher, Kathryn J. Moore	2013	108
14	Extracellular HSP27 acts as a signaling molecule to activate NF-κB in macrophages Cell Stress and Chaperones ·Samira Salari, Tara Seibert, Yong‐Xiang Chen, Tieqiang Hu, Chunhua Shi, Xiaoling Zhao, Charles M. Cuerrier, Joshua E. Raizman, Edward R. O’Brien	2012	102
15	Extracellular Release of the Atheroprotective Heat Shock Protein 27 Is Mediated by Estrogen and Competitively Inhibits acLDL Binding to Scavenger Receptor-A Circulation Research ·Katey J. Rayner, Yong-Xiang Chen, Melissa S. McNulty, Trevor Simard, Xioaling Zhao, Dominic J. Wells, Jacqueline de Belleroche, Edward R. O’Brien	2008	102
16	In vitro investigation of individual and combined cytotoxic effects of ochratoxin A and other selected mycotoxins on renal cells Toxicology in Vitro ·Alexandra H. Heussner, Daniel R. Dietrich, Edward R. O’Brien	2005	99
17	Extracellular Release and Signaling by Heat Shock Protein 27: Role in Modifying Vascular Inflammation Frontiers in Immunology ·Zarah Batulan, Vivek Krishna Pulakazhi Venu, Yumei Li, Gérémy Abdull Koumbadinga, Daiana Alvarez-Olmedo, Chunhua Shi, Edward R. O’Brien	2016	96
18	βig-h3, a Transforming Growth Factor–β–Inducible Gene, Is Overexpressed in Atherosclerotic and Restenotic Human Vascular Lesions Arteriosclerosis Thrombosis and Vascular Biology ·Edward R. O’Brien, Kelly L. Bennett, Michael R. Garvin, Ted W. Zderic, Tomoaki Hinohara, John B. Simpson, Takeshi Kimura, Masakiyo Nobuyoshi, Henry F. Mizgala, A F Purchio, Stephen M. Schwartz	1996	95
19	Assessment of Factors Important in Atherosclerotic Occlusion and Restenosis Thrombosis and Haemostasis ·Stephen M. Schwartz, M A Reidy, Edward R. O’Brien	1995	87
20	Comparison of Early Mortality of Paramedic-Diagnosed ST-Segment Elevation Myocardial Infarction With Immediate Transport to a Designated Primary Percutaneous Coronary Intervention Center to That of Similar Patients Transported to the Nearest Hospital The American Journal of Cardiology ·Michel R. Le May, (unknown), Richard Dionne, (unknown), Jayne Spiller, Derek So, Andrew C.T. Ha, (unknown), Chris Glover, (unknown), Edward R. O’Brien, Ian G. Stiell, (unknown), Marino Labinaz	2006	78

About Edward R. O’Brien

Edward R. O’Brien is a scholar working on Molecular Biology, Surgery, Cardiology and Cardiovascular Medicine, Immunology and Radiology, Nuclear Medicine and Imaging, having authored 150 papers that have together received 6.1k indexed citations. Recurring topics across this work include Coronary Interventions and Diagnostics (43 papers), Heat shock proteins research (25 papers), Acute Myocardial Infarction Research (19 papers), Angiogenesis and VEGF in Cancer (16 papers), Atherosclerosis and Cardiovascular Diseases (15 papers), Cardiac Imaging and Diagnostics (14 papers), Antiplatelet Therapy and Cardiovascular Diseases (12 papers) and Cell Adhesion Molecules Research (10 papers). The work is most often cited by research in Cardiology and Cardiovascular Medicine (1.8k citations), Immunology and Allergy (402 citations), Internal Medicine (228 citations), Microbiology (354 citations) and Cancer Research (636 citations). Edward R. O’Brien has collaborated with scholars based in Canada, United States and United Kingdom. Frequent co-authors include Stephen M. Schwartz, Denis deBlois, Stephen M. Schwartz, Marino Labinaz, Benjamin Hibbert, John B. Simpson, Tomoaki Hinohara, Douglas K. Stewart, Yong-Xiang Chen and Jean-François Marquis. Their work appears in journals such as Circulation, Canadian Journal of Cardiology, Arteriosclerosis Thrombosis and Vascular Biology, Journal of the American College of Cardiology and The FASEB Journal.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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About Edward R. O’Brien

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