Matthew Brook

3.0k citations

20 papers · 2.6k indexed · h-index 17

Impact in

Cancer Research top 5%
- NF-κB Signaling Pathways
Immunology top 5%
- Immune Response and Inflammation

Papers in

Cancer Research 6
- NF-κB Signaling Pathways 4
Biochemistry 2

Co-authors: Andrew R. Clark Jeremy Saklatvala Jonathan L. E. Dean Gareth Sully Nicola K. Gray Kamal R Mahtani Marina Lasa Achim D. Gruber
Journals: Molecular and Cellular Biology (4 papers)Biochemical Society Transactions (3 papers)Proceedings of the National Academy of Sciences (2 papers)FEBS Letters (2 papers)Journal of Biological Chemistry (2 papers)
Partner nations: United Kingdom United States Netherlands

In The Last Decade

Matthew Brook

20 papers receiving 2.6k citations

Peers

Countries citing papers authored by Matthew Brook

Since Specialization

Citations

This map shows the geographic impact of Matthew Brook's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Matthew Brook with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Matthew Brook more than expected).

Fields of papers citing papers by Matthew Brook

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Matthew Brook. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Matthew Brook. The network helps show where Matthew Brook may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Matthew Brook, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Matthew Brook Line = papers co-authored together Matthew Brook links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Quantification of persulfidation on specific proteins: are we nearly there yet? Essays in Biochemistry ·Hongling Liu, Florentina Negoita, Matthew Brook, Kei Sakamoto, Nicholas M. Morton	2024	1
2	Neutrophil-derived alpha defensins control inflammation by inhibiting macrophage mRNA translation Proceedings of the National Academy of Sciences ·Matthew Brook, WU Fei-chang, Katherine Miles, Richard W. Smith, Adriano G. Rossi, Pieter S. Hiemstra, Aisha A. Al Ghamdi, Jonathan L. E. Dean, Nicola K. Gray, Wuyuan Lu, Mohini Gray	2016	67
3	Modulation of the cytoplasmic functions of mammalian post-transcriptional regulatory proteins by methylation and acetylation: a key layer of regulation waiting to be uncovered? Biochemical Society Transactions ·Sarrazin Robert, Nicola K. Gray, Matthew Brook	2015	16
4	Embryonic poly(A)-binding protein (ePAB) phosphorylation is required for Xenopus oocyte maturation Biochemical Journal ·Kyle Friend, Matthew Brook, Marija Kuralt, Michael Sheets, Nicola K. Gray, Emre Seli	2012	25
5	The role of mammalian poly(A)-binding proteins in co-ordinating mRNA turnover Biochemical Society Transactions ·Matthew Brook, Nicola K. Gray	2012	36
6	The multifunctional poly(A)-binding protein (PABP) 1 is subject to extensive dynamic post-translational modification, which molecular modelling suggests plays an important role in co-ordinating its activities Biochemical Journal ·Matthew Brook, Luisa Hoetzsch, James P. Reddington, Zhi-Liang Lu, Nicholas A. Morrice, Nicola K. Gray	2012	36
7	DAZAP1, an RNA-binding protein required for development and spermatogenesis, can regulate mRNA translation RNA ·Richard Smith, Ross C. Anderson, E Trombik, Matthew Brook, William Richardson, Nicola K. Gray	2011	40
8	Poly(A)-binding proteins are functionally distinct and have essential roles during vertebrate development Proceedings of the National Academy of Sciences ·Barbara Gorgoni, William Richardson, Hannah M. Burgess, Ross C. Anderson, Gavin S. Wilkie, Philippe Gautier, Willy Karlove, Matthew Brook, Michael Sheets, Nicola K. Gray	2011	45
9	Themis2/ICB1 Is a Signaling Scaffold That Selectively Regulates Macrophage Toll-Like Receptor Signaling and Cytokine Production PLoS ONE ·Matthew J. Peirce, Matthew Brook, Nicholas A. Morrice, Robert J. Snelgrove, Shajna Begum, Alessandra Lanfrancotti, Clare A. Notley, Tracy Hussell, Andrew P. Cope, Robin Wait	2010	35
10	Poly(A)-Binding Protein 1 Partially Relocalizes to the Nucleus during Herpes Simplex Virus Type 1 Infection in an ICP27-Independent Manner and Does Not Inhibit Virus Replication Journal of Virology ·Christine Salaün, Alasdair I. MacDonald, 成子中島, JK O'DWYER, A. Pozhitkov, Hannah M. Burgess, Matthew Brook, Poonam Malik, Nicola K. Gray, Sheila V. Graham	2010	44
11	Cytoplasmic mRNA: move it, use it or lose it! Biochemical Society Transactions ·Mark J. Coldwell, Nicola K. Gray, Matthew Brook	2010	2
12	The DAZL and PABP families: RNA-binding proteins with interrelated roles in translational control in oocytes Reproduction ·Matthew Brook, E Trombik, Nicola K. Gray	2009	88
13	Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 Regulates Tumor Necrosis Factor mRNA Stability and Translation Mainly by Altering Tristetraprolin Expression, Stability, and Binding to Adenine/Uridine-Rich Element Molecular and Cellular Biology ·Edward Hitti, Tatiana Iakovleva, Matthew Brook, Stefanie Deppenmeier, Achim D. Gruber, Danuta Radzioch, Andrew R. Clark, Perry J. Blackshear, Alexey Kotlyarov, Matthias Gaestel	2006	343
14	Posttranslational Regulation of Tristetraprolin Subcellular Localization and Protein Stability by p38 Mitogen-Activated Protein Kinase and Extracellular Signal-Regulated Kinase Pathways Molecular and Cellular Biology ·Matthew Brook, Cynthia Knapp Dlugosz, Tomàs Santalucı́a, Joanne McIlrath, J. Simon C. Arthur, Jeremy Saklatvala, Andrew R. Clark	2006	223
15	The Stability of Tristetraprolin mRNA Is Regulated by Mitogen-activated Protein Kinase p38 and by Tristetraprolin Itself Journal of Biological Chemistry ·Cynthia Knapp Dlugosz, Matthew Brook, Jeremy Saklatvala, Andrew R. Clark	2004	135
16	Mitogen-Activated Protein Kinase p38 Controls the Expression and Posttranslational Modification of Tristetraprolin, a Regulator of Tumor Necrosis Factor Alpha mRNA Stability Molecular and Cellular Biology ·Kamal R Mahtani, Matthew Brook, Jonathan L. E. Dean, Gareth Sully, Jeremy Saklatvala, Andrew R. Clark	2001	390
17	Dexamethasone Destabilizes Cyclooxygenase 2 mRNA by Inhibiting Mitogen-Activated Protein Kinase p38 Molecular and Cellular Biology ·Marina Lasa, Matthew Brook, Jeremy Saklatvala, Andrew R. Clark	2001	223
18	Regulation of tumour necrosis factor α mRNA stability by the mitogen‐activated protein kinase p38 signalling cascade FEBS Letters ·Matthew Brook, Gareth Sully, Andrew R. Clark, Jeremy Saklatvala	2000	197
19	p38 Mitogen-activated Protein Kinase Regulates Cyclooxygenase-2 mRNA Stability and Transcription in Lipopolysaccharide-treated Human Monocytes Journal of Biological Chemistry ·Jonathan L. E. Dean, Matthew Brook, Andrew R. Clark, Jeremy Saklatvala	1999	461
20	A p38 MAP kinase inhibitor regulates stability of interleukin‐1‐induced cyclooxygenase‐2 mRNA FEBS Letters ·Simon H. Ridley, Jonathan L. E. Dean, S J Sarsfield, Matthew Brook, Andrew R. Clark, Jeremy Saklatvala	1998	191

About Matthew Brook

Matthew Brook is a scholar working on Cancer Research, Biochemistry, Molecular Biology, Immunology and Pharmacology, having authored 20 papers that have together received 2.6k indexed citations. Recurring topics across this work include RNA Research and Splicing (12 papers), RNA modifications and cancer (4 papers), RNA regulation and disease (4 papers), NF-κB Signaling Pathways (4 papers), Immune Response and Inflammation (3 papers), Inflammatory mediators and NSAID effects (3 papers), Cancer-related gene regulation (3 papers) and RNA and protein synthesis mechanisms (3 papers). The work is most often cited by research in Cancer Research (636 citations), Immunology (628 citations), Molecular Biology (1.7k citations), Pharmacology (325 citations) and Oncology (494 citations). Matthew Brook has collaborated with scholars based in United Kingdom, United States and Netherlands. Frequent co-authors include Andrew R. Clark, Jeremy Saklatvala, Jonathan L. E. Dean, Gareth Sully, Nicola K. Gray, Kamal R Mahtani, Marina Lasa, Achim D. Gruber, Edward Hitti and Danuta Radzioch. Their work appears in journals such as Molecular and Cellular Biology, Biochemical Society Transactions, Proceedings of the National Academy of Sciences, FEBS Letters and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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