Jonathan D.J. Wrigley

1.3k total citations
24 papers, 950 citations indexed

About

Jonathan D.J. Wrigley is a scholar working on Physiology, Molecular Biology and Pharmacology. According to data from OpenAlex, Jonathan D.J. Wrigley has authored 24 papers receiving a total of 950 indexed citations (citations by other indexed papers that have themselves been cited), including 15 papers in Physiology, 12 papers in Molecular Biology and 8 papers in Pharmacology. Recurrent topics in Jonathan D.J. Wrigley's work include Alzheimer's disease research and treatments (15 papers), Computational Drug Discovery Methods (8 papers) and Cholinesterase and Neurodegenerative Diseases (8 papers). Jonathan D.J. Wrigley is often cited by papers focused on Alzheimer's disease research and treatments (15 papers), Computational Drug Discovery Methods (8 papers) and Cholinesterase and Neurodegenerative Diseases (8 papers). Jonathan D.J. Wrigley collaborates with scholars based in United Kingdom, United States and Sweden. Jonathan D.J. Wrigley's co-authors include Mark S. Shearman, Dirk Beher, Earl E. Clarke, Alan Nadin, Ian Churcher, Timothy Harrison, Agnés C. L. Martin, Andrew P. Owens, Huw D. Lewis and John B. C. Findlay and has published in prestigious journals such as Journal of Biological Chemistry, Nature Communications and Biochemistry.

In The Last Decade

Jonathan D.J. Wrigley

24 papers receiving 929 citations

Peers

Countries citing papers authored by Jonathan D.J. Wrigley

Since Specialization

Citations

This map shows the geographic impact of Jonathan D.J. Wrigley's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jonathan D.J. Wrigley with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jonathan D.J. Wrigley more than expected).

Fields of papers citing papers by Jonathan D.J. Wrigley

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jonathan D.J. Wrigley. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jonathan D.J. Wrigley. The network helps show where Jonathan D.J. Wrigley may publish in the future.

Co-authorship network of co-authors of Jonathan D.J. Wrigley

This figure shows the co-authorship network connecting the top 25 collaborators of Jonathan D.J. Wrigley. A scholar is included among the top collaborators of Jonathan D.J. Wrigley based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jonathan D.J. Wrigley. Jonathan D.J. Wrigley is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	BE-FLARE: a fluorescent reporter of base editing activity reveals editing characteristics of APOBEC3A and APOBEC3B 2018 ·BMC Biology ·Matthew A. Coelho, Songyuan Li, Luna Simona Pane, Mike Firth, Giovanni Ciotta, Jonathan D.J. Wrigley, Maria Emanuela Cuomo, Marcello Maresca, Ben Taylor	37
2	Mapping the sugar dependency for rational generation of a DNA-RNA hybrid-guided Cas9 endonuclease 2017 ·Nature Communications ·(unknown), Michał Biśta, Matthew D. Newton, Anne U. Goeppert, Maria Emanuela Cuomo, Euan Gordon, (unknown), Jon Read, Jonathan D.J. Wrigley, David Rueda, Ben Taylor	54
3	Cell banking for pharmaceutical research 2014 ·Drug Discovery Today ·Jonathan D.J. Wrigley, Eileen McCall, (unknown), (unknown), (unknown), (unknown), Ryan Hicks, Linda Fröderberg	14
4	Enzymatic Characterisation of USP7 Deubiquitinating activity and Inhibition 2011 ·Cell Biochemistry and Biophysics ·Jonathan D.J. Wrigley, (unknown), (unknown), (unknown), Michael A. Walters, S W Peters, Richard Mott, Thorsten Nowak, Richard A. Ward, Peter B. Simpson, Kevin Hudson	21
5	3-Substituted gem-cyclohexane sulfone based γ-secretase inhibitors for Alzheimer’s disease: Conformational analysis and biological activity 2006 ·Bioorganic & Medicinal Chemistry Letters ·Richard A. Jelley, Jason Elliott, Karl R. Gibson, Timothy Harrison, Dirk Beher, Earl E. Clarke, Huw D. Lewis, Mark S. Shearman, Jonathan D.J. Wrigley	14
6	3,4-Fused cyclohexyl sulfones as γ-secretase inhibitors 2006 ·Bioorganic & Medicinal Chemistry Letters ·Duncan Shaw, Jonathan D. Best, (unknown), Alan Nadin, Mark S. Shearman, (unknown), (unknown), Michael Reilly, Brian J. Williams, Jonathan D.J. Wrigley, Timothy Harrison	22
7	The geminal dimethyl analogue of Flurbiprofen as a novel Aβ42 inhibitor and potential Alzheimer’s disease modifying agent 2006 ·Bioorganic & Medicinal Chemistry Letters ·Nicholas Stock, Benito Muñoz, Jonathan D.J. Wrigley, Mark S. Shearman, Dirk Beher, (unknown), Toni Williamson, Gretchen Bain, Weichao Chen, Xiaohui Jiang, (unknown), Peppi Prasit	19
8	Intra- or Intercomplex Binding to the γ-Secretase Enzyme 2006 ·Journal of Biological Chemistry ·Earl E. Clarke, Ian Churcher, (unknown), Jonathan D.J. Wrigley, Huw D. Lewis, Timothy Harrison, Mark S. Shearman, Dirk Beher	30
9	Intra- or Intercomplex Binding to the γ-Secretase Enzyme 2006 ·Journal of Biological Chemistry ·Earl E. Clarke, Ian Churcher, (unknown), Jonathan D.J. Wrigley, Huw D. Lewis, Timothy Harrison, Mark S. Shearman, Dirk Beher	7
10	Cyclic sulfamide γ-secretase inhibitors 2005 ·Bioorganic & Medicinal Chemistry Letters ·Tim Sparey, Dirk Beher, Jonathan D. Best, Mirlinda Biba, José L. Castro, Earl E. Clarke, (unknown), Timothy Harrison, Huw D. Lewis, Andrew Madin, Mark S. Shearman, Bindi Sohal, Nancy N. Tsou, Christopher J. Welch, Jonathan D.J. Wrigley	44
11	4-Substituted cyclohexyl sulfones as potent, orally active γ-secretase inhibitors 2005 ·Bioorganic & Medicinal Chemistry Letters ·Ian Churcher, Dirk Beher, Jonathan D. Best, José L. Castro, Earl E. Clarke, (unknown), Timothy Harrison, Laure Hitzel, Euan R. Kay, (unknown), Huw D. Lewis, (unknown), Russell J. Mortishire‐Smith, Paul Oakley, Michael Reilly, Duncan Shaw, Mark S. Shearman, Martin Teall, (unknown), Jonathan D.J. Wrigley	61
12	Selected Non-steroidal Anti-inflammatory Drugs and Their Derivatives Target γ-Secretase at a Novel Site 2004 ·Journal of Biological Chemistry ·Dirk Beher, Earl E. Clarke, Jonathan D.J. Wrigley, Agnés C. L. Martin, Alan Nadin, Ian Churcher, Mark S. Shearman	144
13	Methionine-rich repeat proteins: a family of membrane-associated proteins which contain unusual repeat regions 2004 ·Biochimica et Biophysica Acta (BBA) - Biomembranes ·Jamie L. Weiss, Nicholas A. Evans, (unknown), Jonathan D.J. Wrigley, (unknown), (unknown), Jeffrey N. Keen, Andreas Holzenburg, John B. C. Findlay	15
14	Functional Overexpression of γ-Secretase Reveals Protease-independent Trafficking Functions and a Critical Role of Lipids for Protease Activity 2004 ·Journal of Biological Chemistry ·Jonathan D.J. Wrigley, Irina Schurov, (unknown), Agnés C. L. Martin, Earl E. Clarke, (unknown), Timothy P. Bonnert, Mark S. Shearman, Dirk Beher	35
15	Conserved residues within the putative active site of γ‐secretase differentially influence enzyme activity and inhibitor binding 2004 ·Journal of Neurochemistry ·Jonathan D.J. Wrigley, (unknown), Omar Nyabi, Earl E. Clarke, Peter Hunt, Alan Nadin, Bart De Strooper, Mark S. Shearman, Dirk Beher	18
16	High affinity, bioavailable 3-Amino-1,4-benzodiazepine-Based γ-Secretase inhibitors 2003 ·Bioorganic & Medicinal Chemistry Letters ·Andrew P. Owens, Alan Nadin, Adam C. Talbot, Earl E. Clarke, Timothy Harrison, Huw D. Lewis, Michael Reilly, Jonathan D.J. Wrigley, José L. Castro	25
17	A new series of potent benzodiazepine γ-secretase inhibitors 2003 ·Bioorganic & Medicinal Chemistry Letters ·Ian Churcher, Kate Ashton, John W. Butcher, Earl E. Clarke, Timothy Harrison, Huw D. Lewis, Andrew P. Owens, Martin Teall, (unknown), Jonathan D.J. Wrigley	47
18	Generation of C‐terminally truncated amyloid‐β peptides is dependent on γ‐secretase activity 2002 ·Journal of Neurochemistry ·Dirk Beher, Jonathan D.J. Wrigley, Andrew P. Owens, Mark S. Shearman	67
19	Pharmacological Knock-down of the Presenilin 1 Heterodimer by a Novel γ-Secretase Inhibitor 2001 ·Journal of Biological Chemistry ·Dirk Beher, Jonathan D.J. Wrigley, Alan Nadin, Geneviève Evin, Colin L. Masters, Timothy Harrison, José L. Castro, Mark S. Shearman	74
20	Peripherin/rds Influences Membrane Vesicle Morphology 2000 ·Journal of Biological Chemistry ·Jonathan D.J. Wrigley, (unknown), (unknown), John B. C. Findlay	65

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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