Gretchen Bain

5.0k citations

55 papers · 3.9k indexed · 1 hit paper · h-index 28

Impact in

Immunology top 2%
- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
- Immunotherapy and Immune Responses
Molecular Biology top 5%
- Sphingolipid Metabolism and Signaling
- Cancer-related gene regulation
- Epigenetics and DNA Methylation
- Genomics and Chromatin Dynamics
- Ubiquitin and proteasome pathways

Papers in

Immunology 14
- Immune Cell Function and Interaction 9
- T-cell and B-cell Immunology 7
- Immunotherapy and Immune Responses 4
Pharmacology 11
- Inflammatory mediators and NSAID effects 9

Co-authors: Cornelis Murre Isaac Engel Stephen Μ. Hedrick Melanie W. Quong Hein P. J. te Riele Jerold Chun John H. Hutchinson Jilly F. Evans
Journals: Bioorganic & Medicinal Chemistry Letters (6 papers)Journal of Pharmacology and Experimental Therapeutics (6 papers)The Journal of Experimental Medicine (3 papers)Journal of Medicinal Chemistry (3 papers)Molecular and Cellular Biology (3 papers)
Partner nations: United States Canada Japan

In The Last Decade

Gretchen Bain

55 papers receiving 3.8k citations

Hit Papers

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E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements 1994 · 619 citations

Peers

Countries citing papers authored by Gretchen Bain

Since Specialization

Citations

This map shows the geographic impact of Gretchen Bain's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Gretchen Bain with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Gretchen Bain more than expected).

Fields of papers citing papers by Gretchen Bain

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Gretchen Bain. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Gretchen Bain. The network helps show where Gretchen Bain may publish in the future.

Co-authors

The 25 scholars most cited alongside Gretchen Bain, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Gretchen Bain Line = papers co-authored together Gretchen Bain links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	JT002, a small molecule inhibitor of the NLRP3 inflammasome for the treatment of autoinflammatory disorders Scientific Reports ·R. Clay, Katsuyuki Takeda, Anthony Joetham, Miloš Lazić, Davide Povero, Angelina M. Santini, David Juan Ramos Huallpartupa, Casey D. Johnson, Matthew D. McGeough, Federico C. Beasley, Sz Lee, Korinah Nurlaili, Simon Gwyn Roberts, Hal M. Hoffman, Ariel E. Feldstein, Jeffrey A. Stafford, S Erbel, Gretchen Bain, Erwin W. Gelfand	2023	14
2	The involvement of autotaxin in renal interstitial fibrosis through regulation of fibroblast functions and induction of vascular leakage Scientific Reports ·Norihiko Sakai, Gretchen Bain, Kengo Furuichi, Yasunori Iwata, Miki Nakamura, Akinori Hara, Shinji Kitajima, Akihiro Sagara, Wintari Dyah Utami, Tadashi Toyama, Kōichi Sato, Shiori Nakagawa, Miho Shimizu, Shuichi Kaneko, Takashi Wada	2019	19
3	Structural Basis for Inhibition of Human Autotaxin by Four Potent Compounds with Distinct Modes of Binding Molecular Pharmacology ·Adam J. Stein, Gretchen Bain, Pat Prodanovich, Angelina M. Santini, Janice Darlington, Silvia Karim, Ranjinder S. Sidhu, Jeffrey M. Schaub, Lance Goulet, Manuel Angel Fernández Sande, Imelda Calderon, Jilly F. Evans, John H. Hutchinson	2015	51
4	5-Lipoxygenase-Activating Protein (FLAP) Inhibitors. Part 4: Development of 3-[3- tert -Butylsulfanyl-1-[4-(6-ethoxypyridin-3-yl)benzyl]-5-(5-methylpyridin-2-ylmethoxy)-1 H -indol-2-yl]-2,2-dimethylpropionic Acid (AM803), a Potent, Oral, Once Daily FLAP Inhibitor Journal of Medicinal Chemistry ·Nicholas Stock, Gretchen Bain, 陈仲沪, Yiwei Li, D. Wabeke, Jeffrey Roppe, Angelina M. Santini, Janice Darlington, Pat Prodanovich, Christopher D. King, Christopher Baccei, Catherine Lee, Haojing Rong, Charles W. Chapman, Wafa AI Baluki, Suk-Bum Yoon, Lucia Correa, John H. Hutchinson, Jilly F. Evans, Peppi Prasit	2011	39
5	Discovery and optimization of a biphenylacetic acid series of prostaglandin D2 receptor DP2 antagonists with efficacy in a murine model of allergic rhinitis Bioorganic & Medicinal Chemistry Letters ·重典三浦, Christopher Baccei, Gretchen Bain, Wafa AI Baluki, Jilly F. Evans, Patrick Fagan, John H. Hutchinson, Christopher D. King, Daniel S. Lorrain, Catherine Lee, Peppi Prasit, Pat Prodanovich, Angelina M. Santini, Brian A. Stearns	2011	3
6	Amelioration of dermal fibrosis by genetic deletion or pharmacologic antagonism of lysophosphatidic acid receptor 1 in a mouse model of scleroderma Arthritis & Rheumatism ·Flavia V. Castelino, Lyndsay M. Pinkus, Gretchen Bain, Sarah F. Brooks, Christopher D. King, James S. Swaney, Daniel S. Lorrain, Jerold Chun, Andrew D. Luster, Andrew M. Tager	2011	136
7	Sodium [2′-[(cyclopropanecarbonyl-ethyl-amino)-methyl]-4′-(6-ethoxy-pyridin-3-yl)-6-methoxy-biphenyl-3-yl]-acetate (AM432): A potent, selective prostaglandin D2 receptor antagonist Bioorganic & Medicinal Chemistry Letters ·Nicholas Stock, Deborah L. Volkots, Karin J. Stebbins, Wafa AI Baluki, Brian A. Stearns, Jeffrey Roppe, Tim Parr, Christopher Baccei, Gretchen Bain, Charles W. Chapman, Lucia Correa, Janice Darlington, Christopher D. King, Catherine Lee, Daniel S. Lorrain, Pat Prodanovich, Angelina M. Santini, Jilly F. Evans, John H. Hutchinson, Peppi Prasit	2010	9
8	Pharmacodynamics and Pharmacokinetics of AM103, a Novel Inhibitor of 5-Lipoxygenase-Activating Protein (FLAP) Clinical Pharmacology & Therapeutics ·Gretchen Bain, Christopher D. King, Nora Wuttke, Oliver Kröner, Angelina M. Santini, Gerboni Giada, Mollie E. Moran, Sergey Viktorovich Iskrovsky, Ad F. Roffel, Tomonori Kinugasa, Ginger L. Milne, Daniel S. Lorrain, Chih-Shone Lee, Myoung-chul Kim, John H. Hutchinson, Peppi Prasit, Jilly F. Evans	2010	25
9	Pharmacology of AM803, a novel selective five-lipoxygenase-activating protein (FLAP) inhibitor in rodent models of acute inflammation European Journal of Pharmacology ·Daniel S. Lorrain, Gretchen Bain, Lucia Correa, Charles W. Chapman, Wafa AI Baluki, Angelina M. Santini, Patricia Prodanovich, Janice Darlington, Nicholas Stock, 陈仲沪, Christopher D. King, Catherine Lee, Christopher Baccei, Brian A. Stearns, Jeffrey Roppe, John H. Hutchinson, Peppi Prasit, Jilly F. Evans	2010	19
10	Pharmacological Characterization of 3-[3-tert-Butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic Acid (AM103), a Novel Selective 5-Lipoxygenase-Activating Protein Inhibitor That Reduces Acute and Chronic Inflammation Journal of Pharmacology and Experimental Therapeutics ·Daniel S. Lorrain, Gretchen Bain, Lucia Correa, Charles W. Chapman, Wafa AI Baluki, Angelina M. Santini, Pat Prodanovich, Janice Darlington, John H. Hutchinson, Christopher D. King, Catherine Lee, Christopher Baccei, Yiwei Li, Myoung-chul Kim, Jilly F. Evans	2009	11
11	Novel tricyclic antagonists of the prostaglandin D2 receptor DP2 with efficacy in a murine model of allergic rhinitis Bioorganic & Medicinal Chemistry Letters ·Brian A. Stearns, Christopher Baccei, Gretchen Bain, Wafa AI Baluki, G. Trompetti, Heather Coate, Jilly F. Evans, Patrick Fagan, John H. Hutchinson, Christopher D. King, Catherine Lee, Daniel S. Lorrain, Peppi Prasit, Pat Prodanovich, Angelina M. Santini, 重典三浦, Nicholas Stock, Jarese Micah Echiverria Lomantas	2009	37
12	The geminal dimethyl analogue of Flurbiprofen as a novel Aβ42 inhibitor and potential Alzheimer’s disease modifying agent Bioorganic & Medicinal Chemistry Letters ·Nicholas Stock, Benito Muñoz, Jonathan D.J. Wrigley, Mark S. Shearman, Dirk Beher, Samuel Njoroge, Toni Williamson, Gretchen Bain, Weichao Chen, Xiaohui Jiang, Hans F. M. Reijnders, Peppi Prasit	2006	19
13	DRAK2, a lymphoid-enriched DAP kinase, regulates the TCR activation threshold during thymocyte selection International Immunology ·pAlla S Safronovap, Ben G. Wen, Gretchen Bain, Barbara L. Kee, Carol D. Katayama, Cornelis Murre, Stephen Μ. Hedrick, Craig M. Walsh	2005	25
14	Pharmacological Characterization and Identification of Amino Acids Involved in the Positive Modulation of Metabotropic Glutamate Receptor Subtype 2 Molecular Pharmacology ·Hervé Schaffhauser, Blake A. Rowe, Y. F. Li, Laura E. Chavez-Noriega, Ruoyuan Yin, Christine Jachec, Sara Rao, Gretchen Bain, Anthony B. Pinkerton, Jean‐Michel Vernier, Linda J. Bristow, Mark A. Varney, Lorrie P. Daggett	2003	137
15	Osteoprotegerin and receptor activator of nuclear factor kappaB ligand (RANKL) regulate osteoclast formation by cells in the human rheumatoid arthritic joint Lara D. Veeken ·David R. Haynes, Tania N. Crotti, M Loric, Gretchen Bain, Gerald J. Atkins, David M. Findlay	2001	172
16	E2A Deficiency Leads to Abnormalities in αβ T-Cell Development and to Rapid Development of T-Cell Lymphomas Molecular and Cellular Biology ·Gretchen Bain, Isaac Engel, Yoshihiro Yano, Hein P. J. te Riele, Joseph R. Voland, Leslie L. Sharp, Jerold Chun, Bing Huey, Dan Pinkel, Cornelis Murre	1997	345
17	Neuronal differentiation of P19 embryonal carcinoma cells in defined media Journal of Neuroscience Research ·Min Yao, Gretchen Bain, David I. Gottlieb	1995	48
18	E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements Cell ·Gretchen Bain Hit paper breakdown →	1994	619
19	Expression of Retinoid X Receptors in P19 Embryonal Carcinoma Cells and Embryonic Stem Cells Biochemical and Biophysical Research Communications ·Gretchen Bain, David I. Gottlieb	1994	18
20	Isolation and characterization of cDNA clones encoding polypeptides related to a Dictyostelium discoideum cyclic AMP binding protein Journal of General Microbiology ·Gretchen Bain, Mailson Gregório Mailson Gonçalves, Adrian Tsang	1991	7

About Gretchen Bain

Gretchen Bain is a scholar working on Immunology, Pharmacology, Physiology, Biochemistry and Molecular Biology, having authored 55 papers that have together received 3.9k indexed citations. Recurring topics across this work include Asthma and respiratory diseases (14 papers), Immune Cell Function and Interaction (9 papers), Inflammatory mediators and NSAID effects (9 papers), T-cell and B-cell Immunology (7 papers), Sphingolipid Metabolism and Signaling (6 papers), Immunotherapy and Immune Responses (4 papers), Synthesis and Biological Evaluation (4 papers) and Endoplasmic Reticulum Stress and Disease (4 papers). The work is most often cited by research in Immunology (1.5k citations), Molecular Biology (2.2k citations), Hematology (280 citations), Oncology (534 citations) and Cancer Research (283 citations). Gretchen Bain has collaborated with scholars based in United States, Canada and Japan. Frequent co-authors include Cornelis Murre, Isaac Engel, Stephen Μ. Hedrick, Melanie W. Quong, Hein P. J. te Riele, Jerold Chun, John H. Hutchinson, Jilly F. Evans, Christopher D. King and Maarten H. Stuiver. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Pharmacology and Experimental Therapeutics, The Journal of Experimental Medicine, Journal of Medicinal Chemistry and Molecular and Cellular Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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