James F. Blake

6.1k citations

57 papers · 2.9k indexed · h-index 31

Organic Chemistry top 1%
Molecular Biology top 10%
Atomic and Molecular Physics, and Optics top 5%
Computational Theory and Mathematics top 1%
Spectroscopy top 2%

Co-authors: William L. Jorgensen Dongchul Lim James B. Matthew Robert D. Clark Joseph M. Leonard J. Kathleen Buckner William Curatolo Franco Lombardo
Topics: Computational Drug Discovery Methods (9 papers)Asymmetric Synthesis and Catalysis (6 papers)Chemical Synthesis and Analysis (6 papers)
Cited by: Organic Chemistry Physical and Theoretical Chemistry Computational Theory and Mathematics
Journals: Journal of the American Chemical Society Cancer Research Physics Today
Partner nations: United States Netherlands Canada

In The Last Decade

James F. Blake

56 papers receiving 2.8k citations

Peers

Countries citing papers authored by James F. Blake

Since Specialization

Citations

This map shows the geographic impact of James F. Blake's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James F. Blake with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James F. Blake more than expected).

Fields of papers citing papers by James F. Blake

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James F. Blake. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James F. Blake. The network helps show where James F. Blake may publish in the future.

Co-authorship network of co-authors of James F. Blake

This figure shows the co-authorship network connecting the top 25 collaborators of James F. Blake. A scholar is included among the top collaborators of James F. Blake based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with James F. Blake. James F. Blake is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Discovery and SAR of spirochromane Akt inhibitors 2011 ·Bioorganic & Medicinal Chemistry Letters ·Nicholas C. Kallan,Keith L. Spencer,James F. Blake,Rui Xu,(unknown),Josef R. Bencsik,Ian S. Mitchell,Susan L. Gloor,Matthew Martinson,Tyler Risom,Stefan Groß,Tony Morales,Wen‐I Wu,Guy Vigers,Barbara J. Brandhuber,Nicholas J. Skelton	33
2	Single-Agent Inhibition of Chk1 Is Antiproliferative in Human Cancer Cell Lines In Vitro and Inhibits Tumor Xenograft Growth In Vivo 2011 ·Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics ·Kurtis D. Davies,Michael Humphries,Francis X. Sullivan,Ira von Carlowitz,Yvan Le Huérou,Peter Mohr,Bin Wang,James F. Blake,Michael A. Lyon,Indrani W. Gunawardana,Mark J. Chicarelli,Eli Wallace,Stefan Groß	22
3	Discovery of dihydrothieno- and dihydrofuropyrimidines as potent pan Akt inhibitors 2010 ·Bioorganic & Medicinal Chemistry Letters ·Josef R. Bencsik,Dengming Xiao,James F. Blake,Nicholas C. Kallan,Ian S. Mitchell,Keith L. Spencer,Rui Xu,Susan L. Gloor,Matthew Martinson,Tyler Risom,Richard Woessner,(unknown),Wen‐I Wu,Guy Vigers,Barbara J. Brandhuber,Nicholas J. Skelton,Wei Wei Prior,Lesley Murray	29
4	Discovery of pyrrolopyrimidine inhibitors of Akt 2010 ·Bioorganic & Medicinal Chemistry Letters ·James F. Blake,Nicholas C. Kallan,Dengming Xiao,Rui Xu,Josef R. Bencsik,Nicholas J. Skelton,Keith L. Spencer,Ian S. Mitchell,Richard Woessner,Susan L. Gloor,Tyler Risom,Stefan Groß,Matthew Martinson,Tony Morales,Guy Vigers,Barbara J. Brandhuber	46
5	Non-nucleoside inhibitors of HCV NS5B polymerase. Part 1: Synthetic and computational exploration of the binding modes of benzothiadiazine and 1,4-benzothiazine HCV NS5b polymerase inhibitors 2009 ·Bioorganic & Medicinal Chemistry Letters ·R. Hendricks,Jay B. Fell,James F. Blake,John P. Fischer,John Robinson,(unknown),Peter J. Stengel,(unknown),Vincent Lévêque,Sophie Le Pogam,Sonal Rajyaguru,Isabel Nájera,John A. Josey,Jason Harris,Steven Swallow	27
6	3-Hydroxyisoquinolines as inhibitors of HCV NS5b RNA-dependent RNA polymerase 2008 ·Bioorganic & Medicinal Chemistry Letters ·R. Hendricks,(unknown),James F. Blake,Jay B. Fell,John P. Fischer,Peter J. Stengel,Vincent Lévêque,(unknown),Sonal Rajyaguru,Isabel Nájera,John A. Josey,Steven Swallow	46
7	Tetrazole and ester substituted tetrahydoquinoxalines as potent cholesteryl ester transfer protein inhibitors 2007 ·Bioorganic & Medicinal Chemistry Letters ·C. Todd Eary,(unknown),Robert D. Groneberg,Laurence E. Burgess,(unknown),Mark D. Drew,James F. Blake,Ellen R. Laird,(unknown),Michael O’Sullivan,Andrew C. Allen,Vivienne Marsh	74
8	Identification and Evaluation of Molecular Properties Related to Preclinical Optimization and Clinical Fate 2005 ·Medicinal Chemistry ·James F. Blake	34
9	Integrating cheminformatic analysis in combinatorial chemistry 2004 ·Current Opinion in Chemical Biology ·James F. Blake	12
10	Consensus scoring for ligand/protein interactions 2002 ·Journal of Molecular Graphics and Modelling ·Robert D. Clark,(unknown),Joseph M. Leonard,James F. Blake,James B. Matthew	314
11	Chemoinformatics – predicting the physicochemical properties of 'drug-like' molecules 2000 ·Current Opinion in Biotechnology ·James F. Blake	98
12	Design, synthesis and biological evaluation of 3-amino-3-phenylpropionamide derivatives as novel μ opioid receptor ligands 2000 ·Bioorganic & Medicinal Chemistry Letters ·Martin P. Allen,James F. Blake,Dianne K. Bryce,(unknown),Spiros Liras,Stafford McLean,(unknown)	10
13	Visualizing substructural fingerprints 2000 ·Journal of Molecular Graphics and Modelling ·Robert D. Clark,David E. Patterson,(unknown),James F. Blake,James B. Matthew	16
14	Inhibition of MMP-1 and MMP-13 with phosphinic acids that exploit binding in the S2 pocket 1999 ·Bioorganic & Medicinal Chemistry Letters ·Lawrence A. Reiter,James P. Rizzi,Jayvardhan Pandit,(unknown),(unknown),Vinod D. Parikh,James F. Blake,Dennis E. Danley,Ellen R. Laird,Arturo Lopez‐Anaya,Lori Lopresti‐Morrow,Mahmoud N. Mansour,(unknown),Peter G. Mitchell,(unknown),Thomas Pauly,(unknown),Gayle K. Schulte,Sue A. Yocum	31
15	The association between CD20 and Src-family Tyrosine kinases requires an additional factor 1998 ·Molecular Immunology ·(unknown),(unknown),James F. Blake,Pauline Johnson,Julie P. Deans	36
16	Inclusion complexation of ziprasidone mesylate with β-cyclodextrin sulfobutyl ether 1998 ·Journal of Pharmaceutical Sciences ·(unknown),(unknown),Walter Massefski,James F. Blake,Erin M. Duffy,Boris A. Chrunyk	69
17	ChemInform Abstract: Stereoselective Alkylations in Rigid Systems. Effect of Remote Substituents on π‐Facial Additions to Lactam Enolates. Stereoselectronic and Steric Effects. 1998 ·ChemInform ·A. I. MEYERS,Mark A. Seefeld,Bruce A. Lefker,James F. Blake,Paul G. Williard	4
18	Glucose Transport-Enhancing and Hypoglycemic Activity of 2-Methyl-2-phenoxy-3-phenylpropanoic Acids 1996 ·Journal of Medicinal Chemistry ·Reinhard Sarges,(unknown),James F. Blake,Jon Bordner,(unknown),Diane M. Hargrove,Judith L. Treadway,E. Michael Gibbs	19
19	Computation of Brain−Blood Partitioning of Organic Solutes via Free Energy Calculations 1996 ·Journal of Medicinal Chemistry ·Franco Lombardo,James F. Blake,William Curatolo	162
20	Novel Benzisoxazole Derivatives as Potent and Selective Inhibitors of Acetylcholinesterase 1994 ·Journal of Medicinal Chemistry ·Anabella Villalobos,James F. Blake,Christopher K. Bíggers,Todd W. Butler,Douglas S. Chapin,Yuhpyng L. Chen,Jeffrey L. Ives,Shawn B. Jones,Dane Liston	92

About James F. Blake

James F. Blake is a scholar working on Organic Chemistry, Physical and Theoretical Chemistry and Catalysis, having authored 57 papers that have together received 2.9k indexed citations. Recurring topics across this work include Computational Drug Discovery Methods (9 papers), Asymmetric Synthesis and Catalysis (6 papers) and Chemical Synthesis and Analysis (6 papers). The work is most often cited by research in Organic Chemistry (1.5k citations), Physical and Theoretical Chemistry (310 citations) and Computational Theory and Mathematics (512 citations). James F. Blake has collaborated with scholars based in United States, Netherlands and Canada. Frequent co-authors include William L. Jorgensen, Dongchul Lim, James B. Matthew, Robert D. Clark, Joseph M. Leonard, J. Kathleen Buckner, William Curatolo, Franco Lombardo, Scott G. Wierschke and Soroosh Shambayati. Their work appears in journals such as Journal of the American Chemical Society, Cancer Research and Physics Today.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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