James F. Blake

6.1k total citations
57 papers, 2.9k citations indexed

About

James F. Blake is a scholar working on Molecular Biology, Organic Chemistry and Oncology. According to data from OpenAlex, James F. Blake has authored 57 papers receiving a total of 2.9k indexed citations (citations by other indexed papers that have themselves been cited), including 24 papers in Molecular Biology, 23 papers in Organic Chemistry and 12 papers in Oncology. Recurrent topics in James F. Blake's work include Computational Drug Discovery Methods (9 papers), Asymmetric Synthesis and Catalysis (6 papers) and Chemical Synthesis and Analysis (6 papers). James F. Blake is often cited by papers focused on Computational Drug Discovery Methods (9 papers), Asymmetric Synthesis and Catalysis (6 papers) and Chemical Synthesis and Analysis (6 papers). James F. Blake collaborates with scholars based in United States, Netherlands and Canada. James F. Blake's co-authors include William L. Jorgensen, Dongchul Lim, James B. Matthew, Robert D. Clark, Joseph M. Leonard, J. Kathleen Buckner, William Curatolo, Franco Lombardo, Scott G. Wierschke and Soroosh Shambayati and has published in prestigious journals such as Journal of the American Chemical Society, Cancer Research and Physics Today.

In The Last Decade

James F. Blake

56 papers receiving 2.8k citations

Peers

James F. Blake

AMPO

CTM

SPECT

Frank K. Brown United States

Yixiang Cao United States

György G. Ferenczy Hungary

Seung Joo Cho South Korea

Gregory J. Tawa United States

Arteum D. Bochevarov United States

Ya‐Jun Zheng United States

Charles H. Reynolds United States

Donald B. Boyd United States

Jeremy G. Vinter United Kingdom

Frank K. Brown United States

James F. Blake

1.1k ×0.7

1.0k ×1.1

392 ×0.8

AMPO

350 ×0.7

CTM

237 ×0.7

SPECT

Citations per year, relative to James F. Blake James F. Blake (= 1×) peers Frank K. Brown

Countries citing papers authored by James F. Blake

Since Specialization

Citations

This map shows the geographic impact of James F. Blake's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James F. Blake with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James F. Blake more than expected).

Fields of papers citing papers by James F. Blake

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James F. Blake. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James F. Blake. The network helps show where James F. Blake may publish in the future.

Co-authorship network of co-authors of James F. Blake

This figure shows the co-authorship network connecting the top 25 collaborators of James F. Blake. A scholar is included among the top collaborators of James F. Blake based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with James F. Blake. James F. Blake is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Kallan, Nicholas C., Keith L. Spencer, James F. Blake, et al.. (2011). Discovery and SAR of spirochromane Akt inhibitors. Bioorganic & Medicinal Chemistry Letters. 21(8). 2410–2414. 33 indexed citations

Davies, Kurtis D., Michael Humphries, Francis X. Sullivan, et al.. (2011). Single-Agent Inhibition of Chk1 Is Antiproliferative in Human Cancer Cell Lines In Vitro and Inhibits Tumor Xenograft Growth In Vivo. Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics. 19(7). 349–363. 22 indexed citations

Bencsik, Josef R., Dengming Xiao, James F. Blake, et al.. (2010). Discovery of dihydrothieno- and dihydrofuropyrimidines as potent pan Akt inhibitors. Bioorganic & Medicinal Chemistry Letters. 20(23). 7037–7041. 29 indexed citations

Blake, James F., Nicholas C. Kallan, Dengming Xiao, et al.. (2010). Discovery of pyrrolopyrimidine inhibitors of Akt. Bioorganic & Medicinal Chemistry Letters. 20(19). 5607–5612. 46 indexed citations

Hendricks, R., Jay B. Fell, James F. Blake, et al.. (2009). Non-nucleoside inhibitors of HCV NS5B polymerase. Part 1: Synthetic and computational exploration of the binding modes of benzothiadiazine and 1,4-benzothiazine HCV NS5b polymerase inhibitors. Bioorganic & Medicinal Chemistry Letters. 19(13). 3637–3641. 27 indexed citations

Hendricks, R., James F. Blake, Jay B. Fell, et al.. (2008). 3-Hydroxyisoquinolines as inhibitors of HCV NS5b RNA-dependent RNA polymerase. Bioorganic & Medicinal Chemistry Letters. 19(2). 410–414. 46 indexed citations

Eary, C. Todd, Robert D. Groneberg, Laurence E. Burgess, et al.. (2007). Tetrazole and ester substituted tetrahydoquinoxalines as potent cholesteryl ester transfer protein inhibitors. Bioorganic & Medicinal Chemistry Letters. 17(9). 2608–2613. 74 indexed citations

Blake, James F.. (2005). Identification and Evaluation of Molecular Properties Related to Preclinical Optimization and Clinical Fate. Medicinal Chemistry. 1(6). 649–655. 34 indexed citations

Blake, James F.. (2004). Integrating cheminformatic analysis in combinatorial chemistry. Current Opinion in Chemical Biology. 8(4). 407–411. 12 indexed citations

10.

Clark, Robert D., et al.. (2002). Consensus scoring for ligand/protein interactions. Journal of Molecular Graphics and Modelling. 20(4). 281–295. 314 indexed citations

11.

Blake, James F.. (2000). Chemoinformatics – predicting the physicochemical properties of 'drug-like' molecules. Current Opinion in Biotechnology. 11(1). 104–107. 98 indexed citations

12.

Allen, Martin P., et al.. (2000). Design, synthesis and biological evaluation of 3-amino-3-phenylpropionamide derivatives as novel μ opioid receptor ligands. Bioorganic & Medicinal Chemistry Letters. 10(6). 523–526. 10 indexed citations

13.

Clark, Robert D., et al.. (2000). Visualizing substructural fingerprints. Journal of Molecular Graphics and Modelling. 18(4-5). 404–411. 16 indexed citations

14.

Reiter, Lawrence A., James P. Rizzi, Jayvardhan Pandit, et al.. (1999). Inhibition of MMP-1 and MMP-13 with phosphinic acids that exploit binding in the S2 pocket. Bioorganic & Medicinal Chemistry Letters. 9(2). 127–132. 31 indexed citations

15.

Blake, James F., et al.. (1998). The association between CD20 and Src-family Tyrosine kinases requires an additional factor. Molecular Immunology. 35(4). 207–214. 36 indexed citations

16.

Massefski, Walter, et al.. (1998). Inclusion complexation of ziprasidone mesylate with β-cyclodextrin sulfobutyl ether. Journal of Pharmaceutical Sciences. 87(12). 1560–1567. 69 indexed citations

17.

MEYERS, A. I., Mark A. Seefeld, Bruce A. Lefker, James F. Blake, & Paul G. Williard. (1998). ChemInform Abstract: Stereoselective Alkylations in Rigid Systems. Effect of Remote Substituents on π‐Facial Additions to Lactam Enolates. Stereoselectronic and Steric Effects.. ChemInform. 29(49). 4 indexed citations

18.

Sarges, Reinhard, James F. Blake, Jon Bordner, et al.. (1996). Glucose Transport-Enhancing and Hypoglycemic Activity of 2-Methyl-2-phenoxy-3-phenylpropanoic Acids. Journal of Medicinal Chemistry. 39(24). 4783–4803. 19 indexed citations

19.

Lombardo, Franco, James F. Blake, & William Curatolo. (1996). Computation of Brain−Blood Partitioning of Organic Solutes via Free Energy Calculations. Journal of Medicinal Chemistry. 39(24). 4750–4755. 162 indexed citations

20.

Villalobos, Anabella, James F. Blake, Christopher K. Bíggers, et al.. (1994). Novel Benzisoxazole Derivatives as Potent and Selective Inhibitors of Acetylcholinesterase. Journal of Medicinal Chemistry. 37(17). 2721–2734. 92 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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