Wayne E. Childers

3.5k citations

73 papers · 2.4k indexed · 1 hit paper · h-index 20

Impact in

Organic Chemistry top 2%
- Synthetic Organic Chemistry Methods
- Asymmetric Synthesis and Catalysis
- Carbohydrate Chemistry and Synthesis
- Chemical synthesis and alkaloids
Biotechnology top 2%
- Marine Sponges and Natural Products

Papers in ⓘ

Molecular Biology 38
- Pharmacological Receptor Mechanisms and Effects 8
- Receptor Mechanisms and Signaling 5
- DNA Repair Mechanisms 5
- DNA and Nucleic Acid Chemistry 4
Organic Chemistry 18

Co-authors: Harold W. Pinnick (2 shared papers)Magid Abou‐Gharbia (42 shared papers)Larry E. Vickery (2 shared papers)James T. Kellis (2 shared papers)C. H. Robinson (1 shared paper)Tomasz Skórski (6 shared papers)Cecil H. Robinson (4 shared papers)Khaled M. Elokely (7 shared papers)
Journals: Journal of Medicinal Chemistry (10 papers)Bioorganic & Medicinal Chemistry Letters (5 papers)ACS Medicinal Chemistry Letters (4 papers)Bioorganic & Medicinal Chemistry (4 papers)Journal of Pharmacology and Experimental Therapeutics (3 papers)
Partner nations: United States Egypt Saudi Arabia

In The Last Decade

Wayne E. Childers

70 papers receiving 2.4k citations

Hit Papers

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Oxidation of α,β-un saturated aldehydes 1981 · 1.0k citations

Peers

Countries citing papers authored by Wayne E. Childers

Since Specialization

Citations

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Fields of papers citing papers by Wayne E. Childers

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Wayne E. Childers. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Wayne E. Childers. The network helps show where Wayne E. Childers may publish in the future.

Co-authors

The 25 scholars most cited alongside Wayne E. Childers, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Wayne E. Childers Line = papers co-authored together Wayne E. Childers links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 73 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Oxidation of α,β-un saturated aldehydes Tetrahedron ·Balkrishna S. Bal, Wayne E. Childers, Harold W. Pinnick Hit paper breakdown →	1981	1031
2	Resistance to BET Bromodomain Inhibitors Is Mediated by Kinome Reprogramming in Ovarian Cancer Cell Reports ·Alison Kurimchak, Claude Shelton, Kelly Duncan, Katherine J. Johnson, Jennifer Brown, Shane W. O’Brien, Rashid Gabbasov, Lauren S. Fink, Yuesheng Li, Nicole Lounsbury, Magid Abou‐Gharbia, Wayne E. Childers, Denise C. Connolly, Jonathan Chernoff, Jeffrey R. Peterson, James S. Duncan	2016	143
3	Personalized synthetic lethality induced by targeting RAD52 in leukemias identified by gene mutation and expression profile Blood ·Kimberly Cramer-Morales, Margaret Nieborowska-Skorska, Kara Scheibner, Michelle R. Padget, David Irvine, Tomasz Śliwiński, Kimberly Haas, Jae Woong Lee, Huimin Geng, Darshan Roy, Artur Słupianek, Feyruz V. Rassool, Mariusz A. Wasik, Wayne E. Childers, Mhairi Copland, Markus Müschen, Curt I. Civin, Tomasz Skórski	2013	110
4	Lecozotan (SRA-333): A Selective Serotonin 1A Receptor Antagonist That Enhances the Stimulated Release of Glutamate and Acetylcholine in the Hippocampus and Possesses Cognitive-Enhancing Properties Journal of Pharmacology and Experimental Therapeutics ·Lee E. Schechter, Daniel L. Smith, Sharon Rosenzweig‐Lipson, Stacey J. Sukoff Rizzo, Lee A. Dawson, Karen L. Marquis, Daniel Jones, M. Piesla, Terrance H. Andree, Stanley Nawoschik, James A. Harder, Matthew Womack, Jerry J. Buccafusco, Alvin V. Terry, Bartley G. Hoebel, Pedro Rada, Michael Kelly, Magid Abou‐Gharbia, James E. Barrett, Wayne E. Childers	2005	107
5	N-Methyl-d-Aspartate Antagonists and Neuropathic Pain: The Search for Relief Journal of Medicinal Chemistry ·Wayne E. Childers, Reinhardt B Baudy	2007	86
6	Estrogen Receptor Antagonists Are Anti-Cryptococcal Agents That Directly Bind EF Hand Proteins and Synergize with FluconazoleIn Vivo mBio ·Arielle Butts, Kristy Koselny, Yeissa Chabrier‐Roselló, Camile P. Semighini, Jessica C. S. Brown, Xuying Wang, Sivakumar Annadurai, Louis DiDone, Julie M. Tabroff, Wayne E. Childers, Magid Abou‐Gharbia, Melanie Wellington, María E. Cárdenas, Hiten D. Madhani, Joseph Heitman, Damian J. Krysan	2014	82
7	Synthesis and SAR of Adatanserin: Novel Adamantyl Aryl- and Heteroarylpiperazines with Dual Serotonin 5-HT_1A and 5-HT₂ Activity as Potential Anxiolytic and Antidepressant Agents Journal of Medicinal Chemistry ·Magid Abou‐Gharbia, Wayne E. Childers, Horace Fletcher, Georgia B. McGaughey, Usha Patel, Michael B. Webb, John P. Yardley, Terrance H. Andree, Carl A. Boast, Robert J. Kucharik, Karen L. Marquis, Herman Morris, Rosemary Scerni, John A. Moyer	1999	72
8	Inhibition of aromatase cytochrome P-450 by 10-oxirane and 10-thiirane substituted androgens. Implications for the structure of the active site. Journal of Biological Chemistry ·James T. Kellis, Wayne E. Childers, C. H. Robinson, Larry E. Vickery	1987	63
9	Identification of a Small Molecule Inhibitor of RAD52 by Structure-Based Selection PLoS ONE ·Katherine Sullivan, Kimberly Cramer-Morales, Daniel L. McElroy, David A. Ostrov, Kimberly Haas, Wayne E. Childers, Robert Hromas, Tomasz Skórski	2016	55
10	Ribosome-Templated Azide–Alkyne Cycloadditions: Synthesis of Potent Macrolide Antibiotics by In Situ Click Chemistry Journal of the American Chemical Society ·Ian Glassford, Christiana N. Teijaro, Samer S. Daher, Amy Weil, Meagan C. Small, Shiv K. Redhu, Dennis Colussi, Marlene A. Jacobson, Wayne E. Childers, Bettina A. Buttaro, Allen W. Nicholson, Alexander D. MacKerell, Barry S. Cooperman, Rodrigo Andrade	2016	54
11	Pharmacologic blockade of 12/15-lipoxygenase ameliorates memory deficits, Aβ and tau neuropathology in the triple-transgenic mice Molecular Psychiatry ·Jin Chu, J. G. Li, Phillip F. Giannopoulos, Benjamin E. Blass, Wayne E. Childers, Magid Abou‐Gharbia, Domenico Praticò	2015	35
12	A novel approach to the synthesis of the cannabinoids The Journal of Organic Chemistry ·Wayne E. Childers, Harold W. Pinnick	1984	30
13	Synthesis and evaluation of Strychnos alkaloids as MDR reversal agents for cancer cell eradication Bioorganic & Medicinal Chemistry ·Surendrachary Munagala, Gopal Sirasani, Praveen Kokkonda, Manali Phadke, Natalia F. Krynetskaia, Peihua Lu, Frances J. Sharom, Sidhartha Chaudhury, Mohamed Diwan M. AbdulHameed, Gregory J. Tawa, Anders Wallqvist, Rogelio L. Martinez, Wayne E. Childers, Magid Abou‐Gharbia, Evgeny Krynetskiy, Rodrigo Andrade	2013	29
14	Discovery of Innovative Therapeutics: Today’s Realities and Tomorrow’s Vision. 2. Pharma’s Challenges and Their Commitment to Innovation Journal of Medicinal Chemistry ·Magid Abou‐Gharbia, Wayne E. Childers	2014	29
15	Emerging From the Unknown: Structural and Functional Features of Agnoprotein of Polyomaviruses Journal of Cellular Physiology ·A. Sami Sarıbaş, Pascale Coric, Anahit Hamazaspyan, William C. Davis, Rachael Axman, Martyn K. White, Magid Abou‐Gharbia, Wayne E. Childers, Jon H. Condra, Serge Bouaziz, Mahmut Safak	2016	28
16	Prodrugs of Perzinfotel with Improved Oral Bioavailability Journal of Medicinal Chemistry ·Reinhardt B Baudy, John A. Butera, Magid Abou‐Gharbia, Hong Chen, Boyd L. Harrison, Uday Jain, Ronald L. Magolda, Jean Y. Sze, Michael R. Brandt, Terri Cummons, Diane Kowal, Menelas N. Pangalos, Bojana Zupan, Matthew Hoffmann, Michael J. May, Cheryl P. Mugford, Jeffrey D. Kennedy, Wayne E. Childers	2009	27
17	Essential roles of Leu/Ile/Phe-rich domain of JC virus agnoprotein in dimer/oligomer formation, protein stability and splicing of viral transcripts Virology ·A. Sami Sarıbaş, Magid Abou‐Gharbia, Wayne E. Childers, Ilker K. Sariyer, Martyn K. White, Mahmut Safak	2013	24
18	Non-NAD-like PARP-1 inhibitors in prostate cancer treatment Biochemical Pharmacology ·Yaroslava Karpova, Chao Wu, Ali Divan, Mark E. McDonnell, Elizabeth Hewlett, Peter Makhov, John Gordon, Min Ye, Allen B. Reitz, Wayne E. Childers, Tomasz Skórski, Vladimir Kolenko, Alexei V. Tulin	2019	24
19	Synthesis of 10.beta.-oxiranyl and 10.beta.-thiiranyl steroids The Journal of Organic Chemistry ·Wayne E. Childers, Paul S. Furth, Mei Jue Shih, Cecil H. Robinson	1988	21
20	A Mitochondrial-targeted purine-based HSP90 antagonist for leukemia therapy Oncotarget ·Kelly G. Bryant, Young Chan Chae, Rogelio L. Martinez, John Gordon, Khaled M. Elokely, Andrew V. Kossenkov, Steven Grant, Wayne E. Childers, Magid Abou‐Gharbia, Dario C. Altieri	2017	21

About Wayne E. Childers

Wayne E. Childers is a scholar working on Molecular Biology, Organic Chemistry, Cellular and Molecular Neuroscience, Oncology and Pharmacology, having authored 73 papers that have together received 2.4k indexed citations. Recurring topics across this work include Neuroscience and Neuropharmacology Research (13 papers), Pharmacological Receptor Mechanisms and Effects (8 papers), Tryptophan and brain disorders (5 papers), Receptor Mechanisms and Signaling (5 papers), DNA Repair Mechanisms (5 papers), Computational Drug Discovery Methods (5 papers), Pain Mechanisms and Treatments (4 papers) and DNA and Nucleic Acid Chemistry (4 papers). The work is most often cited by research in Organic Chemistry (1.2k citations), Biotechnology (225 citations), Pharmacology (384 citations), Molecular Biology (1.1k citations) and Toxicology (52 citations). Wayne E. Childers has collaborated with scholars based in United States, Egypt and Saudi Arabia. Frequent co-authors include Harold W. Pinnick, Magid Abou‐Gharbia, Larry E. Vickery, James T. Kellis, C. H. Robinson, Tomasz Skórski, Cecil H. Robinson, Khaled M. Elokely, John Gordon and Kimberly Cramer-Morales. Their work appears in journals such as Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters, ACS Medicinal Chemistry Letters, Bioorganic & Medicinal Chemistry and Journal of Pharmacology and Experimental Therapeutics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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