Jay H. Kalin

2.6k citations

28 papers · 1.7k indexed · 1 hit paper · h-index 17

Impact in

Oncology top 5%
- Peptidase Inhibition and Analysis
- PARP inhibition in cancer therapy
Molecular Biology top 5%
- Histone Deacetylase Inhibitors Research
- Protein Degradation and Inhibitors
- Epigenetics and DNA Methylation
- DNA Repair Mechanisms

Papers in

Physiology 3
- Adenosine and Purinergic Signaling 3
Oncology 12
- Peptidase Inhibition and Analysis 9

Co-authors: Alan P. Kozikowski Kyle V. Butler Giulio Vistoli Brett Langley Camille Brochier Joel Bergman Philip A. Cole Wayne W. Hancock
Journals: Journal of the American Chemical Society (4 papers)Journal of Medicinal Chemistry (3 papers)Journal of Clinical Investigation (2 papers)PLoS ONE (2 papers)ACS Chemical Neuroscience (1 paper)
Partner nations: United States Italy United Kingdom

In The Last Decade

Jay H. Kalin

28 papers receiving 1.7k citations

Hit Papers

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Rational Design and Simple Chemistry Yield a Superior, Neuroprotective HDAC6 Inhibitor, Tubastatin A 2010 · 620 citations

Peers

Countries citing papers authored by Jay H. Kalin

Since Specialization

Citations

This map shows the geographic impact of Jay H. Kalin's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jay H. Kalin with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jay H. Kalin more than expected).

Fields of papers citing papers by Jay H. Kalin

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jay H. Kalin. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jay H. Kalin. The network helps show where Jay H. Kalin may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Jay H. Kalin, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jay H. Kalin Line = papers co-authored together Jay H. Kalin links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	The Allosteric Regulator Inositol Phosphate Dramatically Affects the Efficacy and Selectivity of Inhibitors for Different HDAC Complexes Journal of the American Chemical Society ·Mohammad Hoseyn Karimi, Almudena Marín Porta, S McGlinn, Christopher J. Millard, Edward A. Brown, Aline Renata Pavan, Siyu Wang, Jay H. Kalin, Jean Leandro dos Santos, Philip A. Cole, James T. Hodgkinson, John W. R. Schwabe	2025	1
2	The CoREST repressor complex mediates phenotype switching and therapy resistance in melanoma Journal of Clinical Investigation ·Muzhou Wu, 李立生, Shigang Cui, Kebede Kebede, T. Yamazaki, Kihyun Park, Mu Chun-gee, Qing Zhang, Jay H. Kalin, Sarah E. Nocco, О.М. Гергет, Amy Xiao, 宮本真太郎, Adam Labadorf, Samuel J. Beck, Faisal Isa Abdel Qader Al-Nawasra, Philip A. Cole, Rhoda M. Alani	2024	7
3	Inhibition of the CoREST Repressor Complex Promotes Wound Re-Epithelialization through the Regulation of Keratinocyte Migration Journal of Investigative Dermatology ·Joan Lien, Iqra Fatima, Elizabeth W Machua, Marta Otero-Viñas, Muzhou Wu, Jay H. Kalin, Philip A. Cole, Vincent Falanga, Rhoda M. Alani, Andrey A. Sharov	2023	6
4	Structure of human spermine oxidase in complex with a highly selective allosteric inhibitor Communications Biology ·Elsie Diaz, Suraj Adhikary, Armand W.J.W. Tepper, Clara Gordon, Rodrigo F. Ortiz‐Meoz, Daniel J. Krosky, Christophe Buyck, Victor Noviandus, Josep Llaveria, Kuilin Wang, Jay H. Kalin, Vincent N. A. Klaren, T. Abe, P.L. Shaffer, Robert B. Kirkpatrick, Rodrigo J. Carbajo, Maren Thomsen, Antonietta Impagliazzo	2022	5
5	Development and characterization of rabbit monoclonal antibodies that recognize human spermine oxidase and application to immunohistochemistry of human cancer tissues PLoS ONE ·Armand W.J.W. Tepper, Gerald Chu, Vincent N. A. Klaren, Jay H. Kalin, Lindsay Michie, Antonietta Impagliazzo	2022	4
6	HDAC2 targeting stabilizes the CoREST complex in renal tubular cells and protects against renal ischemia/reperfusion injury Scientific Reports ·David D. Aufhauser, 阎凯, Seth J. Concors, Monica Zehnder, Zhong Lin Wang, Douglas R. Murken, Arabinda Samanta, Ulf H. Beier, 後藤秀兵, Tricia Bhatti, Yanfeng Wang, Guanghui Ge, Liqing Wang, Shayan Cheraghlou, Florence F. Wagner, Edward B. Holson, Jay H. Kalin, Philip A. Cole, Wayne W. Hancock, Matthew H. Levine	2021	16
7	Inhibiting the coregulator CoREST impairs Foxp3+ Treg function and promotes antitumor immunity Journal of Clinical Investigation ·Yan Xiong, Liqing Wang, Eros Di Giorgio, Tatiana Akimova, Ulf H. Beier, Rongxiang Han, Mina Jugovic, Jay H. Kalin, Philip A. Cole, Wayne W. Hancock	2020	45
8	Lysine-Specific Demethylase 1 Mediates AKT Activity and Promotes Epithelial-to-Mesenchymal Transition in PIK3CA -Mutant Colorectal Cancer Molecular Cancer Research ·Sahil Minhas, Robert A. Policastro, 周向红 ZHOU Xianghong, Shruthi Sriramkumar, Ning Ding, Xiaoyu Lu, Helai P. Mohammad, Sha Cao, Jay H. Kalin, Philip A. Cole, Gabriel E. Zentner, Heather M. O’Hagan	2019	36
9	Investigation into the use of histone deacetylase inhibitor MS-275 as a topical agent for the prevention and treatment of cutaneous squamous cell carcinoma in an SKH-1 hairless mouse model PLoS ONE ·Jay H. Kalin, Abdulkerim Eroglu, Hua Liu, W. David Holtzclaw, Irene M. Leigh, Charlotte M. Proby, Jed W. Fahey, Philip A. Cole, Albena T. Dinkova‐Kostova	2019	12
10	Lysine-14 acetylation of histone H3 in chromatin confers resistance to the deacetylase and demethylase activities of an epigenetic silencing complex eLife ·Mingxuan Wu, Dawn Hayward, Jay H. Kalin, Yun Song, John W. R. Schwabe, Philip A. Cole	2018	48
11	An Fc–Small Molecule Conjugate for Targeted Inhibition of the Adenosine 2A Receptor ChemBioChem ·Carlos Fabián, Jay H. Kalin, Im‐Hong Sun, Mohammed A. Amin, Ying‐Chun Lo, ربا عبدالوهاب حسين الحجران, John P. Giddens, Polina Sysa‐Shah, Kathleen L. Gabrielson, Lai‐Xi Wang, Jonathan D. Powell, Philip A. Cole	2016	3
12	Exploration of the labeling of [¹¹C]tubastatin A at the hydroxamic acid site with [¹¹C]carbon monoxide Journal of Labelled Compounds and Radiopharmaceuticals ·Shuiyu Lu, Yi Zhang, Jay H. Kalin, Lisheng Cai, Alan P. Kozikowski, Victor W. Pike	2015	13
13	Histone deacetylase 6 inhibition improves memory and reduces total tau levels in a mouse model of tau deposition Alzheimer s Research & Therapy ·Maj-Linda B. Selenica, Leif Benner, Steven B. Housley, Z.C. Zhang, Daniel C. Lee, Kevin Nash, Jay H. Kalin, Joel Bergman, Alan P. Kozikowski, Marcia N. Gordon, Dave Morgan	2014	115
14	An Fc Domain Protein–Small Molecule Conjugate as an Enhanced Immunomodulator Journal of the American Chemical Society ·ربا عبدالوهاب حسين الحجران, Marc A. Holbert, Jay H. Kalin, Young‐Hoon Ahn, John P. Giddens, Mohammed A. Amin, Martin S. Taylor, Samuel L. Collins, Yee Chan‐Li, Adam T. Waickman, Carlos Fabián, David M. Bolduc, Daniel J. Leahy, Maureen R. Horton, Lai‐Xi Wang, Jonathan D. Powell, Philip A. Cole	2014	16
15	Chiral Mercaptoacetamides Display Enantioselective Inhibition of Histone Deacetylase 6 and Exhibit Neuroprotection in Cortical Neuron Models of Oxidative Stress ChemMedChem ·Jay H. Kalin, Hankun Zhang, Kate Ranganath, Giulio Vistoli, Alan P. Kozikowski	2012	31
16	RI-1: a chemical inhibitor of RAD51 that disrupts homologous recombination in human cells Nucleic Acids Research ·Brian Budke, Hillary L. Logan, Jay H. Kalin, Nijas Mohamed, W. Cameron McGuire, Luke Miller, Jeremy M. Stark, Alan P. Kozikowski, Douglas K. Bishop, Philip P. Connell	2012	143
17	An Optimized RAD51 Inhibitor That Disrupts Homologous Recombination without Requiring Michael Acceptor Reactivity Journal of Medicinal Chemistry ·Brian Budke, Jay H. Kalin, Michał Pawłowski, Nijas Mohamed, Megan Wu, Alan P. Kozikowski, Philip P. Connell	2012	80
18	Rational Design and Simple Chemistry Yield a Superior, Neuroprotective HDAC6 Inhibitor, Tubastatin A Journal of the American Chemical Society ·Kyle V. Butler, Jay H. Kalin, Camille Brochier, Giulio Vistoli, Brett Langley, Alan P. Kozikowski Hit paper breakdown →	2010	620
19	Creating zinc monkey wrenches in the treatment of epigenetic disorders Current Opinion in Chemical Biology ·Jay H. Kalin, Kyle V. Butler, Alan P. Kozikowski	2009	17
20	Synthesis and antitubercular activity of quaternized promazine and promethazine derivatives Bioorganic & Medicinal Chemistry Letters ·R.J. Nolan, Jay H. Kalin, Gintare Siaulyte, Maryam Sarvar, Amna Haroon, Heather Williams, Sebastian Przewoźnik, Paola Richiez, Sang‐Hyun Cho, Yuehong Wang, Scott G. Franzblau	2006	41

About Jay H. Kalin

Jay H. Kalin is a scholar working on Physiology, Oncology, Molecular Biology, Biochemistry and Rehabilitation, having authored 28 papers that have together received 1.7k indexed citations. Recurring topics across this work include Histone Deacetylase Inhibitors Research (14 papers), Peptidase Inhibition and Analysis (9 papers), Epigenetics and DNA Methylation (5 papers), Protein Degradation and Inhibitors (5 papers), Cancer therapeutics and mechanisms (3 papers), Adenosine and Purinergic Signaling (3 papers), Signaling Pathways in Disease (3 papers) and Ubiquitin and proteasome pathways (3 papers). The work is most often cited by research in Oncology (632 citations), Molecular Biology (1.4k citations), Physiology (52 citations), Organic Chemistry (279 citations) and Pharmacology (119 citations). Jay H. Kalin has collaborated with scholars based in United States, Italy and United Kingdom. Frequent co-authors include Alan P. Kozikowski, Kyle V. Butler, Giulio Vistoli, Brett Langley, Camille Brochier, Joel Bergman, Philip A. Cole, Wayne W. Hancock, Philip P. Connell and Brian Budke. Their work appears in journals such as Journal of the American Chemical Society, Journal of Medicinal Chemistry, Journal of Clinical Investigation, PLoS ONE and ACS Chemical Neuroscience.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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