Edward B. Holson

5.0k total citations · 1 hit paper
45 papers, 3.1k citations indexed

About

Edward B. Holson is a scholar working on Molecular Biology, Oncology and Physiology. According to data from OpenAlex, Edward B. Holson has authored 45 papers receiving a total of 3.1k indexed citations (citations by other indexed papers that have themselves been cited), including 34 papers in Molecular Biology, 9 papers in Oncology and 6 papers in Physiology. Recurrent topics in Edward B. Holson's work include Histone Deacetylase Inhibitors Research (25 papers), Protein Degradation and Inhibitors (12 papers) and Peptidase Inhibition and Analysis (8 papers). Edward B. Holson is often cited by papers focused on Histone Deacetylase Inhibitors Research (25 papers), Protein Degradation and Inhibitors (12 papers) and Peptidase Inhibition and Analysis (8 papers). Edward B. Holson collaborates with scholars based in United States, Lebanon and Austria. Edward B. Holson's co-authors include Florence F. Wagner, Rajiv R. Ratan, Sama F. Sleiman, Lauretta El Hayek, Stephen J. Haggarty, Saravanan S. Karuppagounder, Thomas Stringer, Ipe Ninan, Edwina Abou Haidar and Moses V. Chao and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Edward B. Holson

45 papers receiving 3.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body β-hydroxybutyrate

2016 575 citations Sama F. Sleiman, Lauretta El Hayek et al. eLife profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Edward B. Holson United States	29	1.9k	452	433	363	313	45	3.1k
Christopher J. Phiel United States	20	2.5k 1.3×	741 1.6×	656 1.5×	244 0.7×	749 2.4×	30	3.9k
Felix Hausch Germany	35	2.2k 1.2×	294 0.7×	280 0.6×	468 1.3×	306 1.0×	129	4.8k
M. Lamar Seibenhener United States	27	2.3k 1.2×	647 1.4×	775 1.8×	330 0.9×	214 0.7×	39	4.3k
Orna Levran United States	32	1.8k 1.0×	709 1.6×	751 1.7×	185 0.5×	646 2.1×	75	3.4k
Mark E. Gurney United States	39	2.4k 1.3×	575 1.3×	555 1.3×	284 0.8×	361 1.2×	70	5.3k
Erik Maronde Germany	34	1.2k 0.7×	568 1.3×	718 1.7×	162 0.4×	189 0.6×	79	3.4k
Xueqin Song China	27	1.1k 0.6×	328 0.7×	191 0.4×	296 0.8×	489 1.6×	122	3.3k
Yoshitatsu Sei United States	31	1.4k 0.7×	315 0.7×	666 1.5×	258 0.7×	243 0.8×	78	3.0k
Scott E. Hemby United States	34	2.0k 1.1×	523 1.2×	2.0k 4.7×	189 0.5×	217 0.7×	75	4.5k
Oksana Kaidanovich‐Beilin Canada	21	1.3k 0.7×	315 0.7×	523 1.2×	104 0.3×	397 1.3×	25	2.4k

Countries citing papers authored by Edward B. Holson

Since Specialization

Citations

This map shows the geographic impact of Edward B. Holson's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Edward B. Holson with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Edward B. Holson more than expected).

Fields of papers citing papers by Edward B. Holson

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Edward B. Holson. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Edward B. Holson. The network helps show where Edward B. Holson may publish in the future.

Co-authorship network of co-authors of Edward B. Holson

This figure shows the co-authorship network connecting the top 25 collaborators of Edward B. Holson. A scholar is included among the top collaborators of Edward B. Holson based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Edward B. Holson. Edward B. Holson is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Simon, Christian, Marie Balslev Backe, Mattias Salling Dahllöf, et al.. (2020). Enhancer of Zeste Homolog 2 (EZH2) Mediates Glucolipotoxicity-Induced Apoptosis in β-Cells. International Journal of Molecular Sciences. 21(21). 8016–8016. 6 indexed citations

Lewis, Michael C., Arnold J. Heynen, David C. Stoppel, et al.. (2020). Selective inhibition of glycogen synthase kinase 3α corrects pathophysiology in a mouse model of fragile X syndrome. Science Translational Medicine. 12(544). 43 indexed citations

Karnib, Nabil, Lauretta El Hayek, Patrick Nasrallah, et al.. (2019). Lactate is an antidepressant that mediates resilience to stress by modulating the hippocampal levels and activity of histone deacetylases. Neuropsychopharmacology. 44(6). 1152–1162. 106 indexed citations

Meyer, Yves, Madalee M. Gassaway, Qihong Xu, et al.. (2017). Multiplex quantitative assays indicate a need for reevaluating reported small-molecule TrkB agonists. Science Signaling. 10(493). 66 indexed citations

Schuetze, Katherine B., Matthew S. Stratton, Michael F. Wempe, et al.. (2017). Overlapping and Divergent Actions of Structurally Distinct Histone Deacetylase Inhibitors in Cardiac Fibroblasts. Journal of Pharmacology and Experimental Therapeutics. 361(1). 140–150. 22 indexed citations

Dirice, Ercument, Raymond W.S. Ng, Rachael N. Martínez, et al.. (2017). Isoform-selective inhibitor of histone deacetylase 3 (HDAC3) limits pancreatic islet infiltration and protects female nonobese diabetic mice from diabetes. Journal of Biological Chemistry. 292(43). 17598–17608. 39 indexed citations

Wagner, Florence F., Michel Weïwer, Stefan Steinbacher, et al.. (2016). Kinetic and structural insights into the binding of histone deacetylase 1 and 2 (HDAC1, 2) inhibitors. Bioorganic & Medicinal Chemistry. 24(18). 4008–4015. 63 indexed citations

Sleiman, Sama F., Lauretta El Hayek, Edwina Abou Haidar, et al.. (2016). Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body β-hydroxybutyrate. eLife. 5. 575 indexed citations breakdown →

Olson, David E., Sama F. Sleiman, Megan W. Bourassa, et al.. (2015). Hydroxamate-Based Histone Deacetylase Inhibitors Can Protect Neurons from Oxidative Stress via a Histone Deacetylase-Independent Catalase-Like Mechanism. Chemistry & Biology. 22(4). 439–445. 33 indexed citations

10.

Sleiman, Sama F., David E. Olson, Megan W. Bourassa, et al.. (2014). Hydroxamic Acid-Based Histone Deacetylase (HDAC) Inhibitors Can Mediate Neuroprotection Independent of HDAC Inhibition. Journal of Neuroscience. 34(43). 14328–14337. 25 indexed citations

11.

Barton, Kirston, Nancie M. Archin, Kara S. Keedy, et al.. (2014). Selective HDAC Inhibition for the Disruption of Latent HIV-1 Infection. PLoS ONE. 9(8). e102684–e102684. 64 indexed citations

12.

Frumm, Stacey M., Zi Peng Fan, Kenneth N. Ross, et al.. (2013). Selective HDAC1/HDAC2 Inhibitors Induce Neuroblastoma Differentiation. Chemistry & Biology. 20(5). 713–725. 85 indexed citations

13.

Wang, Yajie, Yanling Zhang, Krista M. Hennig, et al.. (2013). Class I HDAC imaging using [³H]CI-994 autoradiography. Epigenetics. 8(7). 756–764. 24 indexed citations

14.

Wagner, Florence F., et al.. (2013). Small Molecule Inhibitors of Zinc-dependent Histone Deacetylases. Neurotherapeutics. 10(4). 589–604. 78 indexed citations

15.

Schroeder, Frederick A., Michael C. Lewis, Daniel M. Fass, et al.. (2013). A Selective HDAC 1/2 Inhibitor Modulates Chromatin and Gene Expression in Brain and Alters Mouse Behavior in Two Mood-Related Tests. PLoS ONE. 8(8). e71323–e71323. 105 indexed citations

16.

Chou, Danny Hung‐Chieh, Edward B. Holson, Rebecca L. Maglathlin, et al.. (2012). Inhibition of Histone Deacetylase 3 Protects Beta Cells from Cytokine-Induced Apoptosis. Chemistry & Biology. 19(6). 669–673. 79 indexed citations

17.

Pan, Jen Q., Michael C. Lewis, Elizabeth L. Clore, et al.. (2011). AKT Kinase Activity Is Required for Lithium to Modulate Mood-Related Behaviors in Mice. Neuropsychopharmacology. 36(7). 1397–1411. 88 indexed citations

18.

Wilson, Andrew J., Edward B. Holson, Florence F. Wagner, et al.. (2011). The DNA damage mark pH2AX differentiates the cytotoxic effects of small molecule HDAC inhibitors in ovarian cancer cells. Cancer Biology & Therapy. 12(6). 484–493. 41 indexed citations

19.

Bhaskara, Srividya, Sarah K. Knutson, Guochun Jiang, et al.. (2010). Hdac3 Is Essential for the Maintenance of Chromatin Structure and Genome Stability. Cancer Cell. 18(5). 436–447. 287 indexed citations

20.

Pukkila-Worley, Read, et al.. (2009). Antifungal Drug Discovery through the Study of Invertebrate Model Hosts. Current Medicinal Chemistry. 16(13). 1588–1595. 35 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact