Ciro Mercurio

3.4k citations

52 papers · 1.9k indexed · h-index 24

Impact in

Molecular Biology top 5%
- Histone Deacetylase Inhibitors Research
- Epigenetics and DNA Methylation
- Protein Degradation and Inhibitors
- DNA Repair Mechanisms
- Genomics and Chromatin Dynamics
Oncology top 5%
- Cancer-related Molecular Pathways

Papers in

Oncology 20
- Cancer-related Molecular Pathways 11
- Peptidase Inhibition and Analysis 7
Molecular Biology 42
- Histone Deacetylase Inhibitors Research 20
- Protein Degradation and Inhibitors 14
- Epigenetics and DNA Methylation 12
- Cancer-related gene regulation 5
- Ubiquitin and proteasome pathways 4

Co-authors: Saverio Minucci Florian Thaler Roberto Dal Zuffo Pier Giuseppe Pelicci Mario Varasi Marta Molinari Giulio Draetta F Goubin
Journals: European Journal of Medicinal Chemistry (9 papers)ChemMedChem (7 papers)Journal of Medicinal Chemistry (3 papers)Nature Communications (2 papers)Journal of Biological Chemistry (2 papers)
Partner nations: Italy United States Switzerland

In The Last Decade

Ciro Mercurio

51 papers receiving 1.9k citations

Peers

Countries citing papers authored by Ciro Mercurio

Since Specialization

Citations

This map shows the geographic impact of Ciro Mercurio's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ciro Mercurio with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ciro Mercurio more than expected).

Fields of papers citing papers by Ciro Mercurio

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ciro Mercurio. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ciro Mercurio. The network helps show where Ciro Mercurio may publish in the future.

Co-authors

The 25 scholars most cited alongside Ciro Mercurio, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Ciro Mercurio Line = papers co-authored together Ciro Mercurio links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	GTF2I dosage regulates neuronal differentiation and social behavior in 7q11.23 neurodevelopmental disorders Science Advances ·Alejandro Tobon, Reinald Shyti, Carlo Emanuele Villa, Cristina Cheroni, Patricio Fuentes, Sebastiano Trattaro, Nicolò Caporale, Flavia Troglio, Erika Tenderini, Marija Mihailovich, Adara C. Velasco, William T. Gibson, Alessandro Cuomo, Tiziana Bonaldi, Ciro Mercurio, Mario Varasi, Lucy R. Osborne, Giuseppe Testa	2023	15
2	Novel pyridine-containing histone deacetylase inhibitors strongly arrest proliferation, induce apoptosis and modulate miRNAs in cancer cells European Journal of Medicinal Chemistry ·Elisabetta Di Bello, Loja Cuzco, G. Martina, Clemens Zwergel, Rossella Fioravanti, 阎礼, 先納利典, Stefano Tomassi, Davide Corinti, Daniela Passeri, Roberto Pellicciari, Ciro Mercurio, Mario Varasi, Lucia Altucci, Marco Tripodi, Raffaele Strippoli, Angela Nebbioso, Sérgio Valente, Antonello Mai	2022	13
3	Targeting the scaffolding role of LSD1 (KDM1A) poises acute myeloid leukemia cells for retinoic acid–induced differentiation Science Advances ·Madison S. Beeler, Elena Ceccacci, T Kahn Eugene, Amir Hosseini, Yves Louet, Iros Barozzi, Lorenzo Fornasari, Roberto Dal Zuffo, Sérgio Valente, Rossella Fioravanti, Ciro Mercurio, Mario Varasi, Andrea Mattevi, Antonello Mai, Giulio Pavesi, Tiziana Bonaldi, Saverio Minucci	2020	59
4	Novel Pyridine‐Based Hydroxamates and 2′‐Aminoanilides as Histone Deacetylase Inhibitors: Biochemical Profile and Anticancer Activity ChemMedChem ·Clemens Zwergel, Elisabetta Di Bello, Rossella Fioravanti, Mariarosaria Conte, Angela Nebbioso, Roberta Mazzone, Gerald Brosch, Ciro Mercurio, Mario Varasi, Lucia Altucci, Sérgio Valente, Antonello Mai	2020	12
5	High-throughput screening identifies histone deacetylase inhibitors that modulate GTF2I expression in 7q11.23 microduplication autism spectrum disorder patient-derived cortical neurons Molecular Autism ·Francesca Cavallo, Flavia Troglio, Giovanni Fagà, Daniele Fancelli, Reinald Shyti, Sebastiano Trattaro, Matteo Zanella, Giuseppe D’Agostino, James M. Hughes, Maria Rosaria, Mohamad Z. Al-Faiz, Michele Gabriele, 郑春燕, Marija Mihailovich, R. Frank Kooy, Alessandro Rosa, Ciro Mercurio, Mario Varasi, Giuseppe Testa	2020	18
6	Dual modulation of MCL-1 and mTOR determines the response to sunitinib Journal of Clinical Investigation ·Mohamed Elgendy, Amal Kamal Abdel‐Aziz, Salvatore Lorenzo Renne, Зубов Артем Александрович, Giuseppe Procopio, Maurizio Colecchia, Ravindran Kanesvaran, Chee‐Keong Toh, Daniela Bossi, Isabella Pallavicini, José Luis Perez‐Gracia, María D. Lozano, Valeria Giandomenico, Ciro Mercurio, Luisa Lanfrancone, Nicola Fazio, Franco Nolè, Bin Tean Teh, Giuseppe Renne, Saverio Minucci	2016	50
7	Synthesis, biological characterization and molecular modeling insights of spirochromanes as potent HDAC inhibitors European Journal of Medicinal Chemistry ·Florian Thaler, Philip Jetties, Raffaella Amici, Agnese Abate, Andrea Colombo, A. C. Lamas, Lydia Pappas, Roberto Boggio, Giulio Dondio, Stefania Gagliardi, Saverio Minucci, Luca Sartori, Mario Varasi, Ciro Mercurio	2015	28
8	Synthesis, biological activity and mechanistic insights of 1-substituted cyclopropylamine derivatives: A novel class of irreversible inhibitors of histone demethylase KDM1A European Journal of Medicinal Chemistry ·Paola Vianello, Oronza A. Botrugno, J. Castro Villagrana, Giuseppe Ciossani, Paola Dessanti, Antonello Mai, Andrea Mattevi, Giuseppe Meroni, Saverio Minucci, Florian Thaler, Marcello Tortorici, Fabiola Bejarano-Rebolledo, Sérgio Valente, Husein Sahrawi Saimima Saddam, Mario Varasi, Ciro Mercurio	2014	46
9	Beclin 1 restrains tumorigenesis through Mcl-1 destabilization in an autophagy-independent reciprocal manner Nature Communications ·Mohamed Elgendy, Marco Cirò, Amal Kamal Abdel‐Aziz, Giuseppe Belmonte, Roberto Dal Zuffo, Ciro Mercurio, Clelia Miracco, Luisa Lanfrancone, Marco Foiani, Saverio Minucci	2014	66
10	Chiral Resolution and Pharmacological Characterization of the Enantiomers of the Hsp90 Inhibitor 2‐Amino‐7‐[4‐fluoro‐2‐(3‐pyridyl)phenyl]‐4‐methyl‐7,8‐dihydro‐6H‐quinazolin‐5‐one Oxime ChemMedChem ·Raffaella Amici, Chiara Bigogno, Roberto Boggio, Andrea Colombo, Stephen M. Courtney, Roberto Dal Zuffo, Giulio Dondio, Xue-Li Shen, Stefania Gagliardi, Saverio Minucci, Maria Selma da Cunha, Christian Montalbetti, Oomarsing Gooroochurn, Mario Varasi, Stefania Vultaggio, Ciro Mercurio	2014	6
11	tert‐Butylcarbamate‐Containing Histone Deacetylase Inhibitors: Apoptosis Induction, Cytodifferentiation, and Antiproliferative Activities in Cancer Cells ChemMedChem ·Sérgio Valente, Daniela Trisciuoglio, Maria Tardugno, Rosaria Benedetti, Donatella Labella, Daniela Secci, Ciro Mercurio, Roberto Boggio, Stefano Tomassi, Salvatore Di Maro, Ettore Novellino, Lucia Altucci, Donatella Del Bufalo, Antonello Mai, Sandro Cosconati	2013	17
12	Transcriptional Analysis of an E2F Gene Signature as a Biomarker of Activity of the Cyclin-Dependent Kinase Inhibitor PHA-793887 in Tumor and Skin Biopsies from a Phase I Clinical Study Molecular Cancer Therapeutics ·Giuseppe Locatelli, Roberta Bosotti, Marina Ciomei, Maria Gabriella Brasca, Raffaele Calogero, Ciro Mercurio, Francesco Fiorentini, 继东赵, Emanuela Scacheri, 四夕, Arturo Galvani, Enrico Pesenti, Thierry de Baère, Jean‐Charles Soria, Vladimir Lazar, Antonella Isacchi	2010	11
13	Dual Targeting of CDK and Tropomyosin Receptor Kinase Families by the Oral Inhibitor PHA-848125, an Agent with Broad-Spectrum Antitumor Efficacy Molecular Cancer Therapeutics ·Clara Albanese, Rachele Alzani, Nadia Amboldi, Nilla Avanzi, Dario Ballinari, Maria Gabriella Brasca, Claudio Festuccia, Francesco Fiorentini, Giuseppe Locatelli, Wilma Pastori, Veronica Patton, Fulvia Roletto, Francesco Colotta, Arturo Galvani, Antonella Isacchi, Jürgen Moll, Enrico Pesenti, Ciro Mercurio, Marina Ciomei	2010	51
14	Synthesis and Biological Characterization of Amidopropenyl Hydroxamates as HDAC Inhibitors ChemMedChem ·Florian Thaler, Mario Varasi, Andrea Colombo, Roberto Boggio, Cho-ying, Cristine Fajanibo Cariño, L. K. Pande, Veronica Reali, Erik Hunt Wilson, Antonello Mai, Stefania Gagliardi, Giulio Dondio, Saverio Minucci, Ciro Mercurio	2010	13
15	Cross platform microarray analysis for robust identification of differentially expressed genes BMC Bioinformatics ·Roberta Bosotti, Giuseppe Locatelli, Sandra Healy, Emanuela Scacheri, Luca Sartori, Ciro Mercurio, Raffaele Calogero, Antonella Isacchi	2007	47
16	Cyclin-Dependent Kinase 2 Functions in Normal DNA Repair and Is a Therapeutic Target in BRCA1-Deficient Cancers Cancer Research ·Andrew J. Deans, Kum Kum Khanna, Carolyn J. McNees, Ciro Mercurio, Jörg Heierhorst, Grant A. McArthur	2006	93
17	3-Amino-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: A new class of CDK2 inhibitors Bioorganic & Medicinal Chemistry Letters ·Paolo Pevarello, Daniele Fancelli, Anna Vulpetti, Raffaella Amici, Aiqi Lin, Valeria Pittalà, Paola Vianello, Alexander D. Cameron, Marina Ciomei, Ciro Mercurio, James R. Bischoff, Fulvia Roletto, Mario Varasi, Maria Gabriella Brasca	2005	46
18	The Antidiabetic Agent Sodium Tungstate Activates Glycogen Synthesis through an Insulin Receptor-independent Pathway Journal of Biological Chemistry ·Jorge Domínguez, M.C. Muñoz, Delia Zafra, Isabel Sánchez‐Pérez, Susanna Baqué, Martine Caron, Ciro Mercurio, Albert Barberà, Rosario Perona, Ramón Gomis, Joan J. Guinovart	2003	42
19	Protective Effects of Butyric Acid in Colon Cancer Advances in experimental medicine and biology ·Gian Luigi Russo, Valentina Della Pietra, Ciro Mercurio, Rosanna Palumbo, Giuseppe Iacomino, Maria Russo, Mariarosaria Tosto, Vincenzo Zappia	1999	16
20	Biochemical Characterization of p16 - and p18-containing Complexes in Human Cell Lines Journal of Biological Chemistry ·Fulvio Della Ragione, Gian Luigi Russo, Adriana Oliva, Ciro Mercurio, Pedro Ricardo Del Santoro, Valentina Della Pietra, Vincenzo Zappia	1996	46

About Ciro Mercurio

Ciro Mercurio is a scholar working on Oncology, Molecular Biology, Cell Biology, Toxicology and Hematology, having authored 52 papers that have together received 1.9k indexed citations. Recurring topics across this work include Histone Deacetylase Inhibitors Research (20 papers), Protein Degradation and Inhibitors (14 papers), Epigenetics and DNA Methylation (12 papers), Cancer-related Molecular Pathways (11 papers), Peptidase Inhibition and Analysis (7 papers), Microtubule and mitosis dynamics (5 papers), Cancer-related gene regulation (5 papers) and Ubiquitin and proteasome pathways (4 papers). The work is most often cited by research in Molecular Biology (1.4k citations), Oncology (469 citations), Aging (28 citations), Organic Chemistry (298 citations) and Cell Biology (165 citations). Ciro Mercurio has collaborated with scholars based in Italy, United States and Switzerland. Frequent co-authors include Saverio Minucci, Florian Thaler, Roberto Dal Zuffo, Pier Giuseppe Pelicci, Mario Varasi, Marta Molinari, Giulio Draetta, F Goubin, Oronza A. Botrugno and Antonello Mai. Their work appears in journals such as European Journal of Medicinal Chemistry, ChemMedChem, Journal of Medicinal Chemistry, Nature Communications and Journal of Biological Chemistry.

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