Jan H.J. Hoeijmakers

63.1k total citations · 18 hit papers
399 papers, 48.0k citations indexed

About

Jan H.J. Hoeijmakers is a scholar working on Molecular Biology, Cancer Research and Genetics. According to data from OpenAlex, Jan H.J. Hoeijmakers has authored 399 papers receiving a total of 48.0k indexed citations (citations by other indexed papers that have themselves been cited), including 340 papers in Molecular Biology, 73 papers in Cancer Research and 58 papers in Genetics. Recurrent topics in Jan H.J. Hoeijmakers's work include DNA Repair Mechanisms (268 papers), CRISPR and Genetic Engineering (81 papers) and Carcinogens and Genotoxicity Assessment (60 papers). Jan H.J. Hoeijmakers is often cited by papers focused on DNA Repair Mechanisms (268 papers), CRISPR and Genetic Engineering (81 papers) and Carcinogens and Genotoxicity Assessment (60 papers). Jan H.J. Hoeijmakers collaborates with scholars based in Netherlands, United States and Germany. Jan H.J. Hoeijmakers's co-authors include D. Bootsma, Wim Vermeulen, Roland Kanaar, Jan de Wit, Gijsbertus T. J. van der Horst, Dik C. van Gent, Jan Vijg, Harry van Steeg, Wouter de Laat and Geert Weeda and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Jan H.J. Hoeijmakers

396 papers receiving 47.0k citations

Hit Papers

Genome maintenance mechan... 1992 2026 2003 2014 2001 1996 2009 2014 1999 500 1000 1.5k 2.0k 2.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Genome maintenance mechanisms for preventing cancer
    2001 3.0k citations Jan H.J. Hoeijmakers Nature profile →
  2. DNA repair and mutagenesis
    1996 1.9k citations D. Bootsma, Jan H.J. Hoeijmakers Trends in Genetics profile →
  3. DNA Damage, Aging, and Cancer
    2009 1.6k citations Jan H.J. Hoeijmakers profile →
  4. An Essential Role for Senescent Cells in Optimal Wound Healing through Secretion of PDGF-AA
    2014 1.4k citations Jan Vijg, Harry van Steeg et al. profile →
  5. Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms
    1999 1.1k citations Gijsbertus T. J. van der Horst, Jan de Wit et al. Nature profile →
  6. Chromosomal stability and the DNA double-stranded break connection
    2001 939 citations Dik C. van Gent, Jan H.J. Hoeijmakers et al. profile →
  7. Molecular mechanism of nucleotide excision repair
    1999 900 citations Jan H.J. Hoeijmakers et al. profile →
  8. Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
    2007 852 citations Derrick J. Rossi, David Bryder et al. Nature profile →
  9. Understanding nucleotide excision repair and its roles in cancer and ageing
    2014 843 citations Jurgen A. Marteijn, Hannes Lans et al. Nature Reviews Molecular Cell Biology profile →
  10. Cellular senescence drives age-dependent hepatic steatosis
    2017 732 citations Jan H.J. Hoeijmakers, Sander Barnhoorn et al. Nature Communications profile →
  11. Xeroderma Pigmentosum Group C Protein Complex Is the Initiator of Global Genome Nucleotide Excision Repair
    1998 728 citations D. Bootsma, Jan H.J. Hoeijmakers et al. profile →
  12. DNA Repair Helicase: a Component of BTF2 (TFIIH) Basic Transcription Factor
    1993 687 citations Laurent Schaeffer, Richard Roy et al. Science profile →
  13. Sequential Assembly of the Nucleotide Excision Repair Factors In Vivo
    2001 643 citations Wim Vermeulen, Jan H.J. Hoeijmakers et al. profile →
  14. ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes
    1992 608 citations Jan de Wit, Wim Vermeulen et al. Cell profile →
  15. Nucleotide excision repair and human syndromes
    2000 536 citations Jan de Boer, Jan H.J. Hoeijmakers profile →
  16. The central role of DNA damage in the ageing process
    2021 527 citations Joris Pothof, Jan Vijg et al. Nature profile →
  17. A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis
    2006 524 citations Laura J. Niedernhofer, Esther Appeldoorn et al. Nature profile →
  18. Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis
    2016 278 citations Hiroyuki Matsumura, Yasuaki Mohri et al. Science profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Jan H.J. Hoeijmakers Netherlands 107 38.1k 8.4k 7.8k 5.8k 5.2k 399 48.0k
Stephen P. Jackson United Kingdom 119 56.5k 1.5× 9.8k 1.2× 20.9k 2.7× 7.3k 1.3× 4.4k 0.8× 350 66.5k
Steven L. McKnight United States 87 26.7k 0.7× 5.6k 0.7× 3.7k 0.5× 6.2k 1.1× 4.0k 0.8× 149 39.0k
Hediye Erdjument‐Bromage United States 125 53.4k 1.4× 6.0k 0.7× 7.4k 0.9× 5.5k 1.0× 6.7k 1.3× 285 68.1k
Shelley L. Berger United States 94 26.7k 0.7× 3.2k 0.4× 4.5k 0.6× 4.6k 0.8× 3.0k 0.6× 233 35.9k
Chu‐Xia Deng United States 119 31.1k 0.8× 5.5k 0.7× 9.0k 1.1× 7.8k 1.4× 5.3k 1.0× 414 47.2k
Carlos López-Otı́n Spain 107 25.1k 0.7× 13.8k 1.6× 9.8k 1.2× 3.0k 0.5× 8.0k 1.5× 414 51.2k
Michael N. Hall Switzerland 108 34.3k 0.9× 3.5k 0.4× 3.1k 0.4× 3.7k 0.6× 3.9k 0.8× 246 44.9k
Paul Tempst United States 143 62.1k 1.6× 7.6k 0.9× 8.3k 1.1× 6.6k 1.1× 7.7k 1.5× 320 80.8k
C. David Allis United States 143 77.5k 2.0× 5.1k 0.6× 5.7k 0.7× 9.7k 1.7× 2.3k 0.4× 344 87.9k
John Blenis United States 101 39.2k 1.0× 5.6k 0.7× 8.2k 1.0× 2.9k 0.5× 4.7k 0.9× 222 51.9k

Countries citing papers authored by Jan H.J. Hoeijmakers

Since Specialization
Citations

This map shows the geographic impact of Jan H.J. Hoeijmakers's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jan H.J. Hoeijmakers with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jan H.J. Hoeijmakers more than expected).

Fields of papers citing papers by Jan H.J. Hoeijmakers

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jan H.J. Hoeijmakers. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jan H.J. Hoeijmakers. The network helps show where Jan H.J. Hoeijmakers may publish in the future.

Co-authorship network of co-authors of Jan H.J. Hoeijmakers

This figure shows the co-authorship network connecting the top 25 collaborators of Jan H.J. Hoeijmakers. A scholar is included among the top collaborators of Jan H.J. Hoeijmakers based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jan H.J. Hoeijmakers. Jan H.J. Hoeijmakers is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Sproviero, Daisy, César Payán‐Gómez, Chiara Milanese, et al.. (2025). A blood-based DNA damage signature in patients with Parkinson’s disease is associated with disease progression. Nature Aging. 5(9). 1844–1861. 2 indexed citations
2.
Theil, Arjan F., Angela Helfricht, Karel Bezstarosti, et al.. (2024). The small CRL4CSA ubiquitin ligase component DDA1 regulates transcription-coupled repair dynamics. Nature Communications. 15(1). 6374–6374. 8 indexed citations
3.
Izeta, Ander, et al.. (2024). Time is ticking faster for long genes in aging. Trends in Genetics. 40(4). 299–312. 14 indexed citations
4.
Gyenis, Ákos, Jiang Chang, Sander Barnhoorn, et al.. (2023). Genome-wide RNA polymerase stalling shapes the transcriptome during aging. Nature Genetics. 55(2). 268–279. 71 indexed citations
5.
Vermeij, Wilbert P., Marjolein P. Baar, Ewart Kuijk, et al.. (2022). Different responses to DNA damage determine ageing differences between organs. Aging Cell. 21(4). e13562–e13562. 27 indexed citations
6.
Minnee, Robert C., Robert A. Pol, Daphne S. J. Komninos, et al.. (2022). Fasting before living-kidney donation: effect on donor well-being and postoperative recovery: study protocol of a multicenter randomized controlled trial. Trials. 23(1). 18–18. 5 indexed citations
7.
Lans, Hannes, Jan H.J. Hoeijmakers, Wim Vermeulen, & Jurgen A. Marteijn. (2019). The DNA damage response to transcription stress. Nature Reviews Molecular Cell Biology. 20(12). 766–784. 225 indexed citations
8.
Beek, Adriaan A. van, Bruno Sovran, Floor Hugenholtz, et al.. (2016). Supplementation with Lactobacillus plantarum WCFS1 Prevents Decline of Mucus Barrier in Colon of Accelerated Aging Ercc1−/Δ7 Mice. Frontiers in Immunology. 7. 408–408. 52 indexed citations
9.
Matsumura, Hiroyuki, Yasuaki Mohri, Nguyễn Thanh Bình, et al.. (2016). Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis. Science. 351(6273). aad4395–aad4395. 278 indexed citations breakdown →
10.
Naipal, Kishan A.T., Nicole S. Verkaik, Najim Ameziane, et al.. (2014). Functional Ex Vivo Assay to Select Homologous Recombination–Deficient Breast Tumors for PARP Inhibitor Treatment. Clinical Cancer Research. 20(18). 4816–4826. 124 indexed citations
11.
Krijger, Peter H.L., Kyoo‐young Lee, Niek Wit, et al.. (2011). HLTF and SHPRH are not essential for PCNA polyubiquitination, survival and somatic hypermutation: Existence of an alternative E3 ligase. DNA repair. 10(4). 438–444. 52 indexed citations
12.
Rossi, Derrick J., David Bryder, Jun Seita, et al.. (2007). Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Nature. 447(7145). 725–729. 852 indexed citations breakdown →
13.
Beerens, Nancy, Jan H.J. Hoeijmakers, Roland Kanaar, Wim Vermeulen, & Claire Wyman. (2004). The CSB Protein Actively Wraps DNA. Journal of Biological Chemistry. 280(6). 4722–4729. 89 indexed citations
14.
Niedernhofer, Laura J., Hanny Odijk, Magda Budzowska, et al.. (2004). The Structure-Specific Endonuclease Ercc1-Xpf Is Required To Resolve DNA Interstrand Cross-Link-Induced Double-Strand Breaks. Molecular and Cellular Biology. 24(13). 5776–5787. 407 indexed citations
15.
Boer, Jan de, Jaan‐Olle Andressoo, Jan de Wit, et al.. (2002). Premature Aging in Mice Deficient in DNA Repair and Transcription. Science. 296(5571). 1276–1279. 426 indexed citations
16.
Nakatsu, Yoshimichi, Hiroshi Asahina, Elisabetta Citterio, et al.. (2000). . Data Archiving and Networked Services (DANS). 112 indexed citations
17.
Roest, Henk P., Jan de Wit, Marcel Koken, et al.. (1996). Inactivation of the HR6B Ubiquitin-Conjugating DNA Repair Enzyme in Mice Causes Male Sterility Associated with Chromatin Modification. Cell. 86(5). 799–810. 325 indexed citations
18.
Roy, Richard, J P Adamczewski, Thierry Seroz, et al.. (1994). The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor. Cell. 79(6). 1093–1101. 385 indexed citations
19.
Vermeulen, Wim, Anneke J. van Vuuren, Laurent Schaeffer, et al.. (1994). Three Unusual Repair Deficiencies Associated with Transcription Factor BTF2(TFIIH): Evidence for the Existence of a Transcription Syndrome. Cold Spring Harbor Symposia on Quantitative Biology. 59(0). 317–329. 120 indexed citations
20.
Lehmann, Alan R., Jan H.J. Hoeijmakers, A.A. van Zeeland, et al.. (1992). Workshop on DNA repair. Mutation Research/DNA Repair. 273(1). 1–28. 26 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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