Roland Kanaar

20.9k citations

204 papers · 15.4k indexed · 2 hit papers · h-index 66

Molecular Biology top 0.2%
- DNA Repair Mechanisms 129
- CRISPR and Genetic Engineering 47
- DNA and Nucleic Acid Chemistry 31
- Genomics and Chromatin Dynamics 24
- RNA and protein synthesis mechanisms 14
Cancer Research top 0.5%
- Carcinogens and Genotoxicity Assessment 36
Oncology top 0.5%
- PARP inhibition in cancer therapy 36
Aging top 1%
Genetics top 0.5%
Plant Science
- Plant Genetic and Mutation Studies 13

Co-authors: Claire Wyman Jan H.J. Hoeijmakers Dik C. van Gent Jeroen Essers Cees Dekker Magda Budzowska H. Berna Beverloo Nicholas R. Cozzarelli
Cited by: Molecular Biology Cancer Research Oncology
Journals: Nature (2 papers)Science (4 papers)Cell (2 papers)
Partner nations: Netherlands United States France

In The Last Decade

Roland Kanaar

196 papers receiving 15.2k citations

Hit Papers

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Peers

Countries citing papers authored by Roland Kanaar

Since Specialization

Citations

This map shows the geographic impact of Roland Kanaar's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Roland Kanaar with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Roland Kanaar more than expected).

Fields of papers citing papers by Roland Kanaar

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Roland Kanaar. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Roland Kanaar. The network helps show where Roland Kanaar may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Roland Kanaar, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Roland Kanaar Line = papers co-authored together Roland Kanaar links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Position in proton Bragg curve influences DNA damage complexity and survival in head and neck cancer cells Clinical and Translational Radiation Oncology ·Tim Heemskerk,C. Groenendijk,Marta Rovituso,Ernst van der Wal,Wouter van Burik,Konstantinos Chatzipapas,Danny Lathouwers,Roland Kanaar,Jeremy M. C. Brown,Jeroen Essers	2025	2
2	FIGNL1 inhibits homologous recombination in BRCA2 deficient cells by dissociating RAD51 filaments Science ·Raviprasad Kuthethur,Safa Nasrin VZ,Satheesh Kumar Sengodan,Carmen Fonseca,Stefan Braunshier,Nupur Nagar,Ananya Acharya,Xingde Wang,Arjan F. Theil,Oluwakemi Ibini,Eleni-Maria Manolika,Kelly de Koning,Julien Dessapt,Amélie Fradet‐Turcotte,Joyce H.G. Lebbink,Roland Kanaar,Krishna Mohan Poluri,Shyam K. Sharan,Petr Ćejka,A Chaudhuri	2025	0
3	Distinct mobility patterns of BRCA2 molecules at DNA damage sites Nucleic Acids Research ·Maarten W. Paul,Jesse Aaron,Eric Wait,Romano M. van Genderen,Arti Tyagi,Hélène Kabbech,Ihor Smal,Teng‐Leong Chew,Roland Kanaar,Claire Wyman	2024	0
4	Persistent TFIIH binding to non-excised DNA damage causes cell and developmental failure Nature Communications ·Alba Muniesa-Vargas,Carlota Davó-Martínez,Cristina Ribeiro-Silva,Melanie van der Woude,Karen L. Thijssen,Ben Haspels,David Häckes,Ülkem U. Kaynak,Roland Kanaar,Jurgen A. Marteijn,Arjan F. Theil,Maayke M. P. Kuijten,Wim Vermeulen,Hannes Lans	2024	5
5	Hybrid Molecular and Functional Micro-CT Imaging Reveals Increased Myocardial Apoptosis Preceding Cardiac Failure in Progeroid Ercc1 Mice Molecular Imaging and Biology ·Bibi S. van Thiel,Martine de Boer,Yanto Ridwan,Marion G. J. de Kleijnen,Nicole van Vliet,Janette van der Linden,Isa de Beer,Paula M. van Heijningen,Wilbert P. Vermeij,Jan H.J. Hoeijmakers,A.H. Jan Danser,Roland Kanaar,Dirk J. Duncker,Ingrid van der Pluijm,Jeroen Essers	2024	2
6	Functional Homologous Recombination (HR) Screening Shows the Majority of BRCA1/2-Mutant Breast and Ovarian Cancer Cell Lines Are HR-Proficient Cancers ·Titia G. Meijer,John W.M. Martens,Wendy J. C. Prager‐van der Smissen,Nicole S. Verkaik,Corine M. Beaufort,Stanley van Herk,Teresa Robert-Finestra,Remco M. Hoogenboezem,Kirsten Ruigrok-Ritstier,Maarten W. Paul,Joost Gribnau,Eric M. Bindels,Roland Kanaar,Agnes Jager,Dik C. van Gent,Antoinette Hollestelle	2024	3
7	BRCA2-HSF2BP oligomeric ring disassembly by BRME1 promotes homologous recombination Science Advances ·Rania Ghouil,Simona Miron,Koichi Sato,Dejan Ristić,Sari E. van Rossum-Fikkert,Pierre Legrand,Malika Ouldali,Jean-Marie Winter,Virginie Ropars,Gabriel David,Ana‐Andreea Arteni,Claire Wyman,Puck Knipscheer,Roland Kanaar,Alex N. Zelensky,Sophie Zinn‐Justin	2023	2
8	BRCA2 binding through a cryptic repeated motif to HSF2BP oligomers does not impact meiotic recombination Nature Communications ·Rania Ghouil,Simona Miron,Lieke Koornneef,Jasper Veerman,Maarten W. Paul,Marie‐Hélène Le Du,Esther Sleddens–Linkels,Sari E. van Rossum-Fikkert,Yvette van Loon,Natalia Felipe‐Medina,Alberto M. Pendás,Alex Maas,Jeroen Essers,Pierre Legrand,Willy M. Baarends,Roland Kanaar,Sophie Zinn‐Justin,Alex N. Zelensky	2021	10
9	Low dose ionizing radiation strongly stimulates insertional mutagenesis in a γH2AX dependent manner PLoS Genetics ·Alex N. Zelensky,Mascha Schoonakker,Inger Brandsma,Marcel Tijsterman,Dik C. van Gent,Jeroen Essers,Roland Kanaar	2020	10
10	The unstructured linker arms of MutL enable GATC site incision beyond roadblocks during initiation of DNA mismatch repair Nucleic Acids Research ·Yannicka Mardenborough,Kateryna Nitsenko,Charlie Laffeber,Camille Duboc,Enes Sahin,Audrey Quessada-Vial,H.H.K. Winterwerp,Titia K. Sixma,Roland Kanaar,Peter Friedhoff,Terence R. Strick,Joyce H.G. Lebbink	2019	22
11	Fibulin-4 deficiency differentially affects cytoskeleton structure and dynamics as well as TGFβ signaling Cellular Signalling ·Joyce Burger,Nicole van Vliet,Paula van Heijningen,Heena Kumra,Gert‐Jan Kremers,Maria M. Alves,Gert van Cappellen,Hiromi Yanagisawa,Dieter P. Reinhardt,Roland Kanaar,Ingrid van der Pluijm,Jeroen Essers	2019	18
12	On the Mechanism of Hyperthermia-Induced BRCA2 Protein Degradation Cancers ·Nathalie van den Tempel,Alex N. Zelensky,Hanny Odijk,Charlie Laffeber,Christine K. Schmidt,Inger Brandsma,Jeroen Demmers,Przemek M. Krawczyk,Roland Kanaar	2019	18
13	HSF2BP negatively regulates homologous recombination in DNA interstrand crosslink repair Nucleic Acids Research ·Koichi Sato,Inger Brandsma,Sari E. van Rossum-Fikkert,Nicole S. Verkaik,Anneke B. Oostra,Josephine C. Dorsman,Dik C. van Gent,Puck Knipscheer,Roland Kanaar,Alex N. Zelensky	2019	20
14	Functional Ex Vivo Assay Reveals Homologous Recombination Deficiency in Breast Cancer Beyond BRCA Gene Defects Clinical Cancer Research ·Titia G. Meijer,Nicole S. Verkaik,Anieta M. Sieuwerts,Job van Riet,Kishan A.T. Naipal,Carolien H. M. van Deurzen,Michael A. den Bakker,Hein F.B.M. Sleddens,Hendrikus-Jan Dubbink,T. Dorine den Toom,Winand N.M. Dinjens,Esther H. Lips,Petra M. Nederlof,Marcel Smid,Harmen J.G. van de Werken,Roland Kanaar,John W.M. Martens,Agnes Jager,Dik C. van Gent	2018	47
15	Distinct roles of ATM and ATR in the regulation of ARP8 phosphorylation to prevent chromosome translocations eLife ·Jiying Sun,Lin Shi,Aiko Kinomura,Atsuhiko Fukuto,Yasunori Horikoshi,Yukako Oma,Masahiko Harata,Masae Ikura,Tsuyoshi Ikura,Roland Kanaar,Satoshi Tashiro	2018	6
16	Functional Ex Vivo Assay to Select Homologous Recombination–Deficient Breast Tumors for PARP Inhibitor Treatment Clinical Cancer Research ·Kishan A.T. Naipal,Nicole S. Verkaik,Najim Ameziane,Carolien H. M. van Deurzen,Petra ter Brugge,Matty Meijers,Anieta M. Sieuwerts,John W.M. Martens,Mark J. O’Connor,Harry Vrieling,Jan H.J. Hoeijmakers,Jos Jonkers,Roland Kanaar,Johan P. de Winter,Maaike P.G. Vreeswijk,Agnes Jager,Dik C. van Gent	2014	124
17	Structure-Specific Endonucleases Xpf and Mus81 Play Overlapping but Essential Roles in DNA Repair by Homologous Recombination Cancer Research ·Koji Kikuchi,Takeo Narita,Van T. Pham,Junko Iijima,Kouji Hirota,Islam Shamima Keka,Mohiuddin Mohiuddin,Katsuya Okawa,Tetsuya Hori,Tatsuo Fukagawa,Jeroen Essers,Roland Kanaar,Matthew C. Whitby,Kaoru Sugasawa,Yoshihito Taniguchi,Katsumi Kitagawa,Shunichi Takeda	2013	29
18	Caffeine suppresses homologous recombination through interference with RAD51-mediated joint molecule formation Nucleic Acids Research ·Alex N. Zelensky,Humberto Sánchez,Dejan Ristić,Iztok Vidic,Sari E. van Rossum-Fikkert,Jeroen Essers,Claire Wyman,Roland Kanaar	2013	25
19	Effect of the BRCA2 CTRD domain on RAD51 filaments analyzed by an ensemble of single molecule techniques Nucleic Acids Research ·J.T. Holthausen,Marijn T.J. van Loenhout,Humberto Sánchez,D. Ristić,Sarah E. van Rossum-Fikkert,Mauro Modesti,Cees Dekker,Roland Kanaar,Claire Wyman	2011	10
20	The Structure-Specific Endonuclease Ercc1-Xpf Is Required To Resolve DNA Interstrand Cross-Link-Induced Double-Strand Breaks Molecular and Cellular Biology ·Laura J. Niedernhofer,Hanny Odijk,Magda Budzowska,Ellen van Drunen,Alex Maas,Arjan F. Theil,Jan de Wit,N.G.J. Jaspers,H. Berna Beverloo,Jan H.J. Hoeijmakers,Roland Kanaar	2004	407

About Roland Kanaar

Roland Kanaar is a scholar working on Cancer Research, Molecular Biology and Oncology, having authored 204 papers that have together received 15.4k indexed citations. Recurring topics across this work include DNA Repair Mechanisms (129 papers), CRISPR and Genetic Engineering (47 papers), Carcinogens and Genotoxicity Assessment (36 papers), PARP inhibition in cancer therapy (36 papers), DNA and Nucleic Acid Chemistry (31 papers), Genomics and Chromatin Dynamics (24 papers), RNA and protein synthesis mechanisms (14 papers) and Plant Genetic and Mutation Studies (13 papers). The work is most often cited by research in Molecular Biology (13.0k citations), Cancer Research (2.6k citations) and Oncology (3.3k citations). Roland Kanaar has collaborated with scholars based in Netherlands, United States and France. Frequent co-authors include Claire Wyman, Jan H.J. Hoeijmakers, Dik C. van Gent, Jeroen Essers, Cees Dekker, Magda Budzowska, H. Berna Beverloo, Nicholas R. Cozzarelli, Jan de Wit and Ellen van Drunen. Their work appears in journals such as Nature, Science and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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