Steven L. McKnight

47.0k citations

149 papers · 39.0k indexed · 28 hit papers · h-index 87

Molecular Biology top 0.05%
Genetics top 0.1%
Cancer Research top 0.1%
Immunology top 0.5%
Physiology top 0.2%

Co-authors: Peter F. Johnson William Landschulz Robert C. Kingsbury Richard K. Bruick Robert M. Umek Z Cao Leeju C. Wu Masato Kato
Topics: RNA Research and Splicing (38 papers)RNA and protein synthesis mechanisms (24 papers)Herpesvirus Infections and Treatments (18 papers)
Cited by: Aging Molecular Biology Cancer Research
Journals: Nature Science Cell
Partner nations: United States Japan South Africa

In The Last Decade

Steven L. McKnight

147 papers receiving 37.9k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 3.0k citations Steven L. McKnight et al. Science profile →
A Conserved Family of Prolyl-4-Hydroxylases That Modify HIF

2001 2.1k citations Richard K. Bruick, Steven L. McKnight Science profile →
Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels

2012 1.5k citations Masato Kato, Leeju C. Wu et al. profile →
Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells.

1991 1.5k citations Steven L. McKnight et al. profile →
Transcriptional Control Signals of a Eukaryotic Protein-Coding Gene

1982 1.3k citations Steven L. McKnight et al. Science profile →
EUKARYOTIC TRANSCRIPTIONAL REGULATORY PROTEINS

1989 1.1k citations Steven L. McKnight et al. Annual Review of Biochemistry profile →
Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells.

1997 1.1k citations Steven L. McKnight, David W. Russell et al. profile →
Isolation of a recombinant copy of the gene encoding C/EBP.

1988 917 citations Steven L. McKnight et al. profile →
Scissors-Grip Model for DNA Recognition by a Family of Leucine Zipper Proteins

1989 886 citations Steven L. McKnight et al. Science profile →
Regulation of Clock and NPAS2 DNA Binding by the Redox State of NAD Cofactors

2001 836 citations Jared Rutter, Martin Reick et al. Science profile →
Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins.

1995 804 citations Steven L. McKnight et al. profile →
An Interleukin-4-Induced Transcription Factor: IL-4 Stat

1994 743 citations Steven L. McKnight et al. Science profile →
Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression.

1988 732 citations Steven L. McKnight et al. profile →
Logic of the Yeast Metabolic Cycle: Temporal Compartmentalization of Cellular Processes

2005 697 citations Benjamin P. Tu, Andrzej Kudlicki et al. Science profile →
Transcriptional selectivity of viral genes in mammalian cells

1986 664 citations Steven L. McKnight et al. profile →
Influence of Metabolism on Epigenetics and Disease

2013 654 citations Steven L. McKnight et al. profile →
CCAAT-Enhancer Binding Protein: A Component of a Differentiation Switch

1991 648 citations Steven L. McKnight et al. Science profile →
Cell-free Formation of RNA Granules: Bound RNAs Identify Features and Components of Cellular Assemblies

2012 639 citations Masato Kato, Leeju C. Wu et al. profile →
Analysis of transcriptional regulatory signals of the HSV thymidine kinase gene: Identification of an upstream control region

1981 602 citations Steven L. McKnight et al. profile →
The DNA Binding Domain of the Rat Liver Nuclear Protein C/EBP Is Bipartite

1989 597 citations Steven L. McKnight et al. Science profile →
Tissue-specific expression, developmental regulation, and genetic mapping of the gene encoding CCAAT/enhancer binding protein.

1989 594 citations Steven L. McKnight et al. profile →
Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal viruses.

1987 590 citations Steven L. McKnight et al. profile →
Structure of FUS Protein Fibrils and Its Relevance to Self-Assembly and Phase Separation of Low-Complexity Domains

2017 565 citations Dylan T. Murray, Masato Kato et al. profile →
Acetate Dependence of Tumors

2014 539 citations Robert E. Hammer, Steven L. McKnight et al. profile →
Homologous recognition of a promoter domain common to the MSV LTR and the HSV tk gene

1986 534 citations Steven L. McKnight et al. profile →
The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development

1998 518 citations Hui Tian, Robert E. Hammer et al. profile →
The nucleotide sequence and transcript map of the herpes simplex virus thymidine kinase gene

1980 494 citations Steven L. McKnight profile →
Poly-dipeptides encoded by the C9orf72 repeats bind nucleoli, impede RNA biogenesis, and kill cells

2014 465 citations Ilmin Kwon, Siheng Xiang et al. Science profile →

Peers

Countries citing papers authored by Steven L. McKnight

Since Specialization

Citations

This map shows the geographic impact of Steven L. McKnight's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Steven L. McKnight with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Steven L. McKnight more than expected).

Fields of papers citing papers by Steven L. McKnight

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Steven L. McKnight. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Steven L. McKnight. The network helps show where Steven L. McKnight may publish in the future.

Co-authorship network of co-authors of Steven L. McKnight

This figure shows the co-authorship network connecting the top 25 collaborators of Steven L. McKnight. A scholar is included among the top collaborators of Steven L. McKnight based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Steven L. McKnight. Steven L. McKnight is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Oxidative regulation of TDP-43 self-association by a β-to-α conformational switch 2023 ·Proceedings of the National Academy of Sciences ·Jinge Gu,Xiaoming Zhou,Lillian B. Sutherland,Masato Kato,(unknown),Josep Rizo,Steven L. McKnight	8
2	Mutations linked to neurological disease enhance self-association of low-complexity protein sequences 2022 ·Science ·Xiaoming Zhou,(unknown),(unknown),Lillian B. Sutherland,(unknown),Tian Qin,Masato Kato,Glen Liszczak,Steven L. McKnight	63
3	The low-complexity domain of the FUS RNA binding protein self-assembles via the mutually exclusive use of two distinct cross-β cores 2021 ·Proceedings of the National Academy of Sciences ·Masato Kato,Steven L. McKnight	22
4	Transiently structured head domains control intermediate filament assembly 2021 ·Proceedings of the National Academy of Sciences ·Xiaoming Zhou,Yi Lin,Masato Kato,Eiichiro Mori,Glen Liszczak,Lillian B. Sutherland,Vasiliy O. Sysoev,Dylan T. Murray,Robert Tycko,Steven L. McKnight	43
5	Bariatric Berberi; The Other Thiamine Deficiency (2409) 2021 ·Neurology ·(unknown),Steven L. McKnight	1
6	Dynamic structural order of a low-complexity domain facilitates assembly of intermediate filaments 2020 ·Proceedings of the National Academy of Sciences ·Vasiliy O. Sysoev,Masato Kato,Lillian B. Sutherland,Rong Hu,Steven L. McKnight,Dylan T. Murray	19
7	Redox-mediated regulation of an evolutionarily conserved cross-β structure formed by the TDP43 low complexity domain 2020 ·Proceedings of the National Academy of Sciences ·Yi Lin,Xiaoming Zhou,Masato Kato,Daifei Liu,Sina Ghaemmaghami,Benjamin P. Tu,Steven L. McKnight	44
8	Structural characterization of the D290V mutation site in hnRNPA2 low-complexity–domain polymers 2018 ·Proceedings of the National Academy of Sciences ·Dylan T. Murray,Xiaoming Zhou,Masato Kato,Siheng Xiang,Robert Tycko,Steven L. McKnight	38
9	Poly-dipeptides encoded by the C9orf72 repeats bind nucleoli, impede RNA biogenesis, and kill cellsbreakdown → 2014 ·Science ·Ilmin Kwon,Siheng Xiang,Masato Kato,Leeju C. Wu,(unknown),Tao Wang,Jiwoong Kim,Jonghyun Yun,Yang Xie,Steven L. McKnight	465
10	Dependence of Mouse Embryonic Stem Cells on Threonine Catabolism 2009 ·Science ·Jian Wang,Peter B. Alexander,Leeju C. Wu,Robert E. Hammer,Ondine Cleaver,Steven L. McKnight	292
11	NPAS2 as a transcriptional regulator of non-rapid eye movement sleep: Genotype and sex interactions 2006 ·Proceedings of the National Academy of Sciences ·Paul Franken,Carol A. Dudley,Sandi Jo Estill,Monique T. Barakat,(unknown),Bruce F. O’Hara,Steven L. McKnight	151
12	Mammalian sprouty proteins assemble into large monodisperse particles having the properties of intracellular nanobatteries 2005 ·Proceedings of the National Academy of Sciences ·Xinle Wu,Peter B. Alexander,Ying He,Masahide Kikkawa,Pia D. Vogel,Steven L. McKnight	18
13	Logic of the Yeast Metabolic Cycle: Temporal Compartmentalization of Cellular Processesbreakdown → 2005 ·Science ·Benjamin P. Tu,Andrzej Kudlicki,Maga Rowicka,Steven L. McKnight	697
14	Altered Patterns of Sleep and Behavioral Adaptability in NPAS2-Deficient Mice 2003 ·Science ·Carol A. Dudley,(unknown),Sandi Jo Estill,Martin Reick,Paul Franken,(unknown),Steven L. McKnight	327
15	NPAS2: A Gas-Responsive Transcription Factor 2002 ·Science ·Elhadji M. Dioum,Jared Rutter,Jason R. Tuckerman,G. González,Marie‐Alda Gilles‐Gonzalez,Steven L. McKnight	350
16	Metabolism and the Control of Circadian Rhythms 2002 ·Annual Review of Biochemistry ·Jared Rutter,Martin Reick,Steven L. McKnight	323
17	A Conserved Family of Prolyl-4-Hydroxylases That Modify HIFbreakdown → 2001 ·Science ·Richard K. Bruick,Steven L. McKnight	2096
18	NPAS2: An Analog of Clock Operative in the Mammalian Forebrain 2001 ·Science ·Martin Reick,Joseph A. Garcia,Carol A. Dudley,Steven L. McKnight	451
19	Molecular characterization of two mammalian bHLH-PAS domain proteins selectively expressed in the central nervous system 1997 ·Proceedings of the National Academy of Sciences ·(unknown),(unknown),Hui Tian,Xu Li,Huijun Z. Ring,Uta Francke,John M. Shelton,James A. Richardson,David W. Russell,Steven L. McKnight	164
20	29 CCAAT/Enhancer Binding Protein 1992 ·Cold Spring Harbor Monograph Archive ·Steven L. McKnight	11

About Steven L. McKnight

Steven L. McKnight is a scholar working on Molecular Biology, Endocrine and Autonomic Systems and Aging, having authored 149 papers that have together received 39.0k indexed citations. Recurring topics across this work include RNA Research and Splicing (38 papers), RNA and protein synthesis mechanisms (24 papers) and Herpesvirus Infections and Treatments (18 papers). The work is most often cited by research in Aging (702 citations), Molecular Biology (26.7k citations) and Cancer Research (5.6k citations). Steven L. McKnight has collaborated with scholars based in United States, Japan and South Africa. Frequent co-authors include Peter F. Johnson, William Landschulz, Robert C. Kingsbury, Richard K. Bruick, Robert M. Umek, Z Cao, Leeju C. Wu, Masato Kato, Barbara J. Graves and Martin Reick. Their work appears in journals such as Nature, Science and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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