C. David Allis

120.2k citations

344 papers · 87.9k indexed · 45 hit papers · h-index 143

Impact in

Molecular Biology top 0.01%
- Epigenetics and DNA Methylation
- Genomics and Chromatin Dynamics
- Cancer-related gene regulation
- RNA modifications and cancer
- Histone Deacetylase Inhibitors Research
- Protein Degradation and Inhibitors
- Ubiquitin and proteasome pathways
- RNA Research and Splicing
Aging top 0.1%

Papers in

Molecular Biology 334
- Genomics and Chromatin Dynamics 192
- Epigenetics and DNA Methylation 165
- Cancer-related gene regulation 83
- RNA modifications and cancer 59
- Protist diversity and phylogeny 53
- Ubiquitin and proteasome pathways 34
- Histone Deacetylase Inhibitors Research 30
- Protein Degradation and Inhibitors 29
Genetics 28

Co-authors: Thomas Jenuwein Brian D. Strahl Emily Bernstein Yanming Wang Alexander J. Ruthenburg Wolfgang Fischle Haitao Li Richard G. Cook
Journals: Proceedings of the National Academy of Sciences (37 papers)Journal of Biological Chemistry (27 papers)Cell (23 papers)Nature (22 papers)Molecular and Cellular Biology (21 papers)
Partner nations: United States Canada France

In The Last Decade

C. David Allis

343 papers receiving 86.5k citations

Hit Papers

15 papers align trajectories log scale

The language of chromatin modification in human cancers 2021 · 249 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2021 Nature reviews. Cancer
2016 Nature Reviews Molecular Cell Biology
2016 Nature Reviews Genetics
2014 Nature
2013 Science
2010 Nature reviews. Cancer
2010 Proceedings of the National Academy of Sciences
2009 The Journal of Cell Biology
2007 Molecular Cell
2007 Nature Structural & Molecular Biology
2007 Cell
2007 Nature Protocols
2007 Nature Reviews Molecular Cell Biology
2007 Nature
2006 Nature
2006 Nature
2006 Nature Structural & Molecular Biology
2005 Nature
2005 Cell
2005 Cell
2004 Science
2003 Nature
2003 Science
2003 Molecular Cell
2003 Current Opinion in Cell Biology
2003 Genes & Development
2002 Molecular and Cellular Biology
2002 Nature
2002 Molecular Cell
2001 Science
2001 Science
2001 Current Opinion in Cell Biology
2001 Science
2001 Science
2001 Annual Review of Biochemistry
2000 Cell
2000 Cell
2000 Nature
2000 Molecular Cell
2000 Nature
1999 Cell
1998 BioEssays
1997 Genes & Development
1996 Cell
1993 Genes & Development

Peers

Countries citing papers authored by C. David Allis

Since Specialization

Citations

This map shows the geographic impact of C. David Allis's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by C. David Allis with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites C. David Allis more than expected).

Fields of papers citing papers by C. David Allis

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by C. David Allis. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by C. David Allis. The network helps show where C. David Allis may publish in the future.

Co-authors

The 25 scholars most cited alongside C. David Allis, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with C. David Allis Line = papers co-authored together C. David Allis links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Histone butyrylation in the mouse intestine is mediated by the microbiota and associated with regulation of gene expression Nature Metabolism ·Leah Gates, Bernardo Sgarbi Reis, Peder J. Lund, Matthew R. Paul, Marylène Leboeuf, João Paulo Sardo Madi, Myy Hung, Mariana Lopes, Saeed Isah, Gökhan Ünlü, Thomas S. Carroll, Kıvanç Birsoy, Benjamin A. García, Daniel Mucida, C. David Allis	2024	25
2	Lead Optimization of Small Molecule ENL YEATS Inhibitors to Enable In Vivo Studies: Discovery of TDI-11055 ACS Medicinal Chemistry Letters ·Mayako Michino, Dhale Yogita Balasaheb, Michael W. Miller, Yoshiyuki Fukase, Jérémie Vendôme, Carolina Adura, J. Fraser Glickman, Yiman Liu, Liling Wan, C. David Allis, Andrew W. Stamford, Peter T. Meinke, Louis M. Renzetti, Stacia Kargman, Nigel J. Liverton, David J. Huggins	2024	2
3	Cancer-associated Histone H3 N-terminal arginine mutations disrupt PRC2 activity and impair differentiation Nature Communications ·Benjamin A. Nacev, محمدحسین بنابازی, Matthew R. Paul, 英蔵中川, Michelle M. Mitchener, Salma Alkhatib, Fang Yan, Alexey A. Soshnev, Douglas Barrows, Usme Sabogal, Nicholas D. Socci, Yeon-Ju Seo, Deng Hai-zhong, Michael Gruß, Sébastien Monette, William D. Tap, Benjamin A. Garcia, Tom W. Muir, C. David Allis	2024	4
4	Histone bivalency regulates the timing of cerebellar granule cell development Genes & Development ·Kärt Mätlik, Eve‐Ellen Govek, Matthew R. Paul, C. David Allis, Mary E. Hatten	2023	15
5	Oncohistone mutations enhance chromatin remodeling and alter cell fates Nature Chemical Biology ·John D. Bagert, Michelle M. Mitchener, G. F. Kislitsin, Barbara E. Dul, Felix Wojcik, Benjamin A. Nacev, Lijuan Feng, C. David Allis, Tom W. Muir	2021	58
6	Depletion of H3K36me2 recapitulates epigenomic and phenotypic changes induced by the H3.3K36M oncohistone mutation Proceedings of the National Academy of Sciences ·Kartik N. Rajagopalan, Xiao Chen, Daniel N. Weinberg, Haifeng Chen, Jacek Majewski, C. David Allis, Chao Lü	2021	34
7	Histone H3.3 G34 mutations promote aberrant PRC2 activity and drive tumor progression Proceedings of the National Academy of Sciences ·Siddhant U. Jain, Sima Khazaei, Dylan M. Marchione, Stefan Lundgren, Xiaoshi Wang, Daniel N. Weinberg, Shriya Deshmukh, Nikoleta Juretic, Chao Lü, C. David Allis, Benjamin A. García, Nada Jabado, Peter W. Lewis	2020	70
8	Loss of UTX/KDM6A and the activation of FGFR3 converge to regulate differentiation gene-expression programs in bladder cancer Proceedings of the National Academy of Sciences ·Douglas Barrows, Lijuan Feng, Thomas S. Carroll, C. David Allis	2020	30
9	Epigenomic Reprogramming as a Driver of Malignant Glioma Cancer Cell ·Richard E. Phillips, Alexey A. Soshnev, C. David Allis	2020	71
10	Structure-guided development of YEATS domain inhibitors by targeting π-π-π stacking Nature Chemical Biology ·Xin Li, Xiaomeng Li, Yixiang Jiang, Zheng Liu, Yiwen Cui, Binfeng He, Mohd Nazlin Bin Kamarudin, Gaofei Tian, Liling Wan, Xiaobing Shi, C. David Allis, Haitao Li, Yuanyuan Li, Xiang Li	2018	83
11	Interview with C. David Allis, PhD Assay and Drug Development Technologies ·C. David Allis, О.Е. Коновалов	2015	1
12	Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastoma Science ·Peter W. Lewis, Manuel M. Müller, Dorothy McKay, Francisco J. Cordero, Shu Lin, Laura A. Banaszynski, Benjamin A. Garcia, Tom W. Muir, Oren J. Becher, C. David Allis Hit paper breakdown →	2013	898
13	Dynamic Regulation of Effector Protein Binding to Histone Modifications: The Biology of HP1 Switching Cell Cycle ·John Moreland Dishman, Boo Shan Tseng, C. David Allis, Hironori Funabiki, Wolfgang Fischle	2006	47
14	Serine 31 phosphorylation of histone variant H3.3 is specific to regions bordering centromeres in metaphase chromosomes Proceedings of the National Academy of Sciences ·Sandra B. Hake, Benjamin A. García, Saadan Hussain Khan, Stephen P. Baker, Jeffrey Shabanowitz, Donald F. Hunt, C. David Allis	2005	154
15	Human PAD4 Regulates Histone Arginine Methylation Levels via Demethylimination Science ·Yanming Wang, Joanna Wysocka, Joyce Sayegh, Young‐Ho Lee, Julie R. Perlin, Lauriebeth Leonelli, JOHN E. FALK, Alay Phonvisay, Richard G. Cook, Yali Dou, Robert G. Roeder, Steven Clarke, Michael R. Stallcup, C. David Allis, Scott A. Coonrod Hit paper breakdown →	2004	774
16	Epigenetic Dynamics of Imprinted X Inactivation During Early Mouse Development Science ·Ikuhiro Okamoto, Arie P. Otte, C. David Allis, Danny Reinberg, Édith Heard Hit paper breakdown →	2003	630
17	Induction and maintenance of nonsymmetrical DNA methylation in Neurospora Proceedings of the National Academy of Sciences ·Eric U. Selker, Michael Freitag, Gregory O. Kothe, Brian S. Margolin, Michael R. Rountree, C. David Allis, Hisashi Tamaru	2002	40
18	Transitions in Distinct Histone H3 Methylation Patterns at the Heterochromatin Domain Boundaries Science ·Ken-ichi Noma, C. David Allis, Shiv I. S. Grewal Hit paper breakdown →	2001	600
19	Requirement of Rsk-2 for Epidermal Growth Factor-Activated Phosphorylation of Histone H3 Science ·Paolo Sassone‐Corsi, Craig A. Mizzen, Peter Cheung, Claudia Crosio, Lucia Monaco, Sylvie Jacquot, André Hanauer, C. David Allis	1999	408
20	[4] Enzyme activity dot blots for assaying protein kinases Methods in enzymology on CD-ROM/Methods in enzymology ·Claiborne V.C. Glover, C. David Allis	1991	11

About C. David Allis

C. David Allis is a scholar working on Molecular Biology, Genetics, Cell Biology, Microbiology and Plant Science, having authored 344 papers that have together received 87.9k indexed citations. Recurring topics across this work include Genomics and Chromatin Dynamics (192 papers), Epigenetics and DNA Methylation (165 papers), Cancer-related gene regulation (83 papers), RNA modifications and cancer (59 papers), Protist diversity and phylogeny (53 papers), Ubiquitin and proteasome pathways (34 papers), Histone Deacetylase Inhibitors Research (30 papers) and Protein Degradation and Inhibitors (29 papers). The work is most often cited by research in Molecular Biology (77.5k citations), Aging (967 citations), Genetics (9.7k citations), Cancer Research (5.1k citations) and Geriatrics and Gerontology (1.0k citations). C. David Allis has collaborated with scholars based in United States, Canada and France. Frequent co-authors include Thomas Jenuwein, Brian D. Strahl, Emily Bernstein, Yanming Wang, Alexander J. Ruthenburg, Wolfgang Fischle, Haitao Li, Richard G. Cook, Dinshaw J. Patel and Min‐Hao Kuo. Their work appears in journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry, Cell, Nature and Molecular and Cellular Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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