Stephen J. Lippard

98.6k citations

937 papers · 82.9k indexed · 26 hit papers · h-index 134

Molecular Biology top 0.02%
Oncology top 0.01%
Organic Chemistry top 0.01%
Materials Chemistry top 0.05%
Inorganic Chemistry top 0.01%

Co-authors: Elizabeth M. Nolan Dong Wang Elizabeth R. Jamieson Timothy C. Johnstone Kogularamanan Suntharalingam Yongwon Jung Shanta Dhar Shawn C. Burdette
Topics: Metal complexes synthesis and properties (369 papers)Metal-Catalyzed Oxygenation Mechanisms (282 papers)Magnetism in coordination complexes (160 papers)
Cited by: Inorganic Chemistry Oncology Organic Chemistry
Journals: Nature Science Chemical Reviews
Partner nations: United States United Kingdom Germany

In The Last Decade

Stephen J. Lippard

927 papers receiving 80.3k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Cellular processing of platinum anticancer drugs

2005 3.2k citations Stephen J. Lippard et al. profile →
Structure, Recognition, and Processing of Cisplatin−DNA Adducts

1999 2.6k citations Stephen J. Lippard et al. profile →
Tools and Tactics for the Optical Detection of Mercuric Ion

2008 2.2k citations Elizabeth M. Nolan, Stephen J. Lippard profile →
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs

2016 2.1k citations Kogularamanan Suntharalingam, Stephen J. Lippard et al. profile →
Direct Cellular Responses to Platinum-Induced DNA Damage

2007 1.2k citations Stephen J. Lippard et al. profile →
Characteristics and tectonic significance of supra-subduction zone ophiolites

1984 982 citations Stephen J. Lippard et al. profile →
New metal complexes as potential therapeutics

2003 836 citations Stephen J. Lippard et al. profile →
Structural aspects of platinum anticancer drug interactions with DNA

1987 820 citations Stephen J. Lippard et al. profile →
Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA–PEG nanoparticles

2008 808 citations Omid C. Farokhzad, Stephen J. Lippard et al. Proceedings of the National Academy of Sciences profile →
Crystal structure of a bacterial non-haem iron hydroxylase that catalyses the biological oxidation of methane

1993 735 citations Stephen J. Lippard et al. profile →
Reactions of Non-Heme Iron(II) Centers with Dioxygen in Biology and Chemistry

1994 702 citations Stephen J. Lippard et al. profile →
Fluorescent Sensors for Zn²⁺Based on a Fluorescein Platform: Synthesis, Properties and Intracellular Distribution

2001 678 citations Stephen J. Lippard et al. Journal of the American Chemical Society profile →
Crystal structure of double-stranded DNA containing the major adduct of the anticancer drug cisplatin

1995 650 citations Stephen J. Lippard et al. profile →
A “Turn-On” Fluorescent Sensor for the Selective Detection of Mercuric Ion in Aqueous Media

2003 614 citations Elizabeth M. Nolan, Stephen J. Lippard Journal of the American Chemical Society profile →
Synthetic Models for Non-Heme Carboxylate-Bridged Diiron Metalloproteins: Strategies and Tactics

2004 573 citations Stephen J. Lippard et al. profile →
Small-Molecule Fluorescent Sensors for Investigating Zinc Metalloneurochemistry

2008 560 citations Elizabeth M. Nolan, Stephen J. Lippard profile →
Targeted Single-Wall Carbon Nanotube-Mediated Pt(IV) Prodrug Delivery Using Folate as a Homing Device

2008 543 citations Stephen J. Lippard et al. Journal of the American Chemical Society profile →
Dioxygen Activation and Methane Hydroxylation by Soluble Methane Monooxygenase: A Tale of Two Irons and Three Proteins

2001 540 citations Matthew H. Sazinsky, Stephen J. Lippard et al. profile →
A New Cell-Permeable Fluorescent Probe for Zn²⁺

2000 524 citations Stephen J. Lippard et al. Journal of the American Chemical Society profile →
Cisplatin: From DNA damage to cancer chemotherapy

2001 524 citations Stephen J. Lippard et al. profile →
The ophiolite of northern Oman

1986 511 citations Stephen J. Lippard et al. profile →
Redox activation of metal-based prodrugs as a strategy for drug delivery

2012 433 citations Stephen J. Lippard et al. profile →
CF₂H, a Hydrogen Bond Donor

2017 403 citations Jacob M. Goldberg, Stephen J. Lippard et al. Journal of the American Chemical Society profile →
A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress

2017 379 citations Stephen J. Lippard, Michael T. Hemann et al. profile →
Mononuclear and Polynuclear Chemistry of Rhenium (III): Its Pronounced Homophilicity

1964 334 citations Stephen J. Lippard et al. profile →
HMG-domain proteins specifically inhibit the repair of the major DNA adduct of the anticancer drug cisplatin by human excision nuclease.

1994 295 citations Stephen J. Lippard et al. Proceedings of the National Academy of Sciences profile →

Peers

Countries citing papers authored by Stephen J. Lippard

Since Specialization

Citations

This map shows the geographic impact of Stephen J. Lippard's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Stephen J. Lippard with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Stephen J. Lippard more than expected).

Fields of papers citing papers by Stephen J. Lippard

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Stephen J. Lippard. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Stephen J. Lippard. The network helps show where Stephen J. Lippard may publish in the future.

Co-authorship network of co-authors of Stephen J. Lippard

This figure shows the co-authorship network connecting the top 25 collaborators of Stephen J. Lippard. A scholar is included among the top collaborators of Stephen J. Lippard based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Stephen J. Lippard. Stephen J. Lippard is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Native Zinc Catalyzes Selective and Traceless Release of Small Molecules in β-Cells 2020 ·Journal of the American Chemical Society ·Miseon Lee,Basudeb Maji,Debasish Manna,Sevim Kahraman,(unknown),(unknown),(unknown),Amedeo Vetere,Jacob M. Goldberg,Stephen J. Lippard,Rohit Kulkarni,Bridget K. Wagner,Amit Choudhary	22
2	Enhancing chemotherapy response through augmented synthetic lethality by co-targeting nucleotide excision repair and cell-cycle checkpoints 2020 ·Nature Communications ·Yi Wen Kong,Erik C. Dreaden,Sandra Morandell,Wen Zhou,(unknown),Ganapathy Sriram,Fred C. Lam,Jesse C. Patterson,Mohiuddin Quadir,(unknown),Kevin E. Shopsowitz,Shohreh Varmeh,Ömer Yılmaz,Stephen J. Lippard,Hans Christian Reinhardt,Michael T. Hemann,Paula T. Hammond,Michael B. Yaffe	24
3	A Platinum(IV) Prodrug—Perfluoroaryl Macrocyclic Peptide Conjugate Enhances Platinum Uptake in the Brain 2020 ·Journal of Medicinal Chemistry ·Colin M. Fadzen,Justin M. Wolfe,Wen Zhou,Choi‐Fong Cho,Niklas von Spreckelsen,(unknown),Yen‐Chun Lee,E. Antonio Chiocca,Sean Lawler,Ömer Yılmaz,Stephen J. Lippard,Bradley L. Pentelute	28
4	Glutathione-Scavenging Poly(disulfide amide) Nanoparticles for the Effective Delivery of Pt(IV) Prodrugs and Reversal of Cisplatin Resistance 2018 ·Nano Letters ·Xiang Ling,Xing Chen,Imogen A. Riddell,Wei Tao,Junqing Wang,Geoffrey Hollett,Stephen J. Lippard,Omid C. Farokhzad,Jinjun Shi,Jun Wu	183
5	Conjugation of Vitamin E Analog Î±-TOS to Pt(IV) Complexes for Dual-Targeting Anticancer Therapy 2014 ·Europe PMC (PubMed Central) ·Kogularamanan Suntharalingam,Ying Song,Stephen J. Lippard	95
6	Visualizing Inhibition of Nucleosome Mobility and Transcription by Cisplatin–DNA Interstrand Crosslinks in Live Mammalian Cells 2013 ·Cancer Research ·Guangyu Zhu,Lina Song,Stephen J. Lippard	25
7	Reaction-based fluorescent sensor for investigating mobile Zn ²⁺ in mitochondria of healthy versus cancerous prostate cells 2013 ·Proceedings of the National Academy of Sciences ·Wen Chyan,Daniel Zhang,Stephen J. Lippard,Robert J. Radford	146
8	Chemical Characterization of the Smallest S -Nitrosothiol, HSNO; Cellular Cross-talk of H ₂ S and S -Nitrosothiols 2012 ·Journal of the American Chemical Society ·Miloš R. Filipović,Jan Lj. Miljković,Thomas Nauser,Maksim Royzen,(unknown),Tatyana E. Shubina,Willem H. Koppenol,Stephen J. Lippard,Ivana Ivanović‐Burmazović	289
9	Monofunctional Platinum–DNA Adducts Are Strong Inhibitors of Transcription and Substrates for Nucleotide Excision Repair in Live Mammalian Cells 2011 ·Cancer Research ·Guangyu Zhu,MyatNoeZin Myint,Wee Han Ang,Lina Song,Stephen J. Lippard	67
10	X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct 2010 ·Proceedings of the National Academy of Sciences ·Dong Wang,Guangyu Zhu,Xuhui Huang,Stephen J. Lippard	114
11	A Novel Imaging Approach for Early Detection of Prostate Cancer Based on Endogenous Zinc Sensing 2010 ·Cancer Research ·Subrata Ghosh,Pilhan Kim,Xiaoan Zhang,Seok Hyun Yun,Anna Moore,Stephen J. Lippard,Zdravka Medarova	99
12	Revisiting the Mechanism of Dioxygen Activation in Soluble Methane Monooxygenase from M. capsulatus (Bath): Evidence for a Multi-Step, Proton-Dependent Reaction Pathway 2009 ·Biochemistry ·Christine E. Tinberg,Stephen J. Lippard	79
13	Bacillus anthracis -derived nitric oxide is essential for pathogen virulence and survival in macrophages 2008 ·Proceedings of the National Academy of Sciences ·Konstantin Shatalin,Ivan Gusarov,(unknown),(unknown),Lindsey E. McQuade,Stephen J. Lippard,Evgeny Nudler	158
14	Organic Cation Transporters Are Determinants of Oxaliplatin Cytotoxicity 2006 ·Cancer Research ·Shuzhong Zhang,Katherine S. Lovejoy,James E. Shima,Leah L. Lagpacan,Yan Shu,Anna Lapuk,Ying Chen,Takafumi Komori,Joe W. Gray,Xin Chen,Stephen J. Lippard,Kathleen M. Giacomini	340
15	X-ray Structure of a Hydroxylase−Regulatory Protein Complex from a Hydrocarbon-Oxidizing Multicomponent Monooxygenase, Pseudomonas sp. OX1 Phenol Hydroxylase ^, 2006 ·Biochemistry ·Matthew H. Sazinsky,Pete Dunten,Michael S. McCormick,Alberto Di Donato,Stephen J. Lippard	57
16	Product Bound Structures of the Soluble Methane Monooxygenase Hydroxylase from Methylococcus capsulatus (Bath): Protein Motion in the α-Subunit 2005 ·Journal of the American Chemical Society ·Matthew H. Sazinsky,Stephen J. Lippard	60
17	Hydroxylation of C–H bonds at carboxylate-bridged diiron centres 2005 ·Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences ·Stephen J. Lippard	53
18	A tautomeric zinc sensor for ratiometric fluorescence imaging: Application to nitric oxide-induced release of intracellular zinc 2004 ·Proceedings of the National Academy of Sciences ·Christopher J. Chang,Jacek Jaworski,Elizabeth M. Nolan,Morgan Sheng,Stephen J. Lippard	196
19	MGM volume 48 issue 346 Cover and Front matter 1984 ·Mineralogical Magazine ·Stephen J. Lippard,(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown)	1
20	Isotopic and trace element evidence from lavas, bearing on mantle heterogeneity beneath Kenya 1980 ·Philosophical Transactions of the Royal Society of London Series A Mathematical and Physical Sciences ·Michael J Norry,(unknown),Stephen J. Lippard,Christopher J. Hawkesworth,S. D. Weaver,G. F. Marriner	84

About Stephen J. Lippard

Stephen J. Lippard is a scholar working on Inorganic Chemistry, Oncology and Electronic, Optical and Magnetic Materials, having authored 937 papers that have together received 82.9k indexed citations. Recurring topics across this work include Metal complexes synthesis and properties (369 papers), Metal-Catalyzed Oxygenation Mechanisms (282 papers) and Magnetism in coordination complexes (160 papers). The work is most often cited by research in Inorganic Chemistry (20.9k citations), Oncology (30.7k citations) and Organic Chemistry (21.9k citations). Stephen J. Lippard has collaborated with scholars based in United States, United Kingdom and Germany. Frequent co-authors include Elizabeth M. Nolan, Dong Wang, Elizabeth R. Jamieson, Timothy C. Johnstone, Kogularamanan Suntharalingam, Yongwon Jung, Shanta Dhar, Shawn C. Burdette, Suzanne E. Sherman and Christin Frederick. Their work appears in journals such as Nature, Science and Chemical Reviews.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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