Leanne C. Sayles

2.4k total citations
24 papers, 840 citations indexed

About

Leanne C. Sayles is a scholar working on Molecular Biology, Cancer Research and Oncology. According to data from OpenAlex, Leanne C. Sayles has authored 24 papers receiving a total of 840 indexed citations (citations by other indexed papers that have themselves been cited), including 18 papers in Molecular Biology, 11 papers in Cancer Research and 5 papers in Oncology. Recurrent topics in Leanne C. Sayles's work include Mitochondrial Function and Pathology (5 papers), Cancer Genomics and Diagnostics (5 papers) and Genetics, Aging, and Longevity in Model Organisms (4 papers). Leanne C. Sayles is often cited by papers focused on Mitochondrial Function and Pathology (5 papers), Cancer Genomics and Diagnostics (5 papers) and Genetics, Aging, and Longevity in Model Organisms (4 papers). Leanne C. Sayles collaborates with scholars based in United States, Canada and Germany. Leanne C. Sayles's co-authors include Bernard D. Lemire, E. Alejandro Sweet‐Cordero, Leslie I. Grad, David B. Pilgrim, William Y.W. Tsang, Silvestre Vicent, Joseph B. Shrager, Anna K. Gillespie, Chen Ron and Yanyan Zheng and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Clinical Investigation.

In The Last Decade

Leanne C. Sayles

22 papers receiving 825 citations

Peers

Leanne C. Sayles
Hitomi Saso United States
Zarir E. Karanjawala United States
Crystal S. Conn United States
Franziska K. Lorbeer United States
Hitomi Saso United States
Leanne C. Sayles
Citations per year, relative to Leanne C. Sayles Leanne C. Sayles (= 1×) peers Hitomi Saso

Countries citing papers authored by Leanne C. Sayles

Since Specialization
Citations

This map shows the geographic impact of Leanne C. Sayles's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Leanne C. Sayles with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Leanne C. Sayles more than expected).

Fields of papers citing papers by Leanne C. Sayles

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Leanne C. Sayles. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Leanne C. Sayles. The network helps show where Leanne C. Sayles may publish in the future.

Co-authorship network of co-authors of Leanne C. Sayles

This figure shows the co-authorship network connecting the top 25 collaborators of Leanne C. Sayles. A scholar is included among the top collaborators of Leanne C. Sayles based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Leanne C. Sayles. Leanne C. Sayles is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Sayles, Leanne C., et al.. (2025). Impact of scaffold material choice on osteosarcoma phenotype and drug responses in 3D. Acta Biomaterialia. 205. 164–175.
2.
Lee, Alex G., Leanne C. Sayles, N. Sörensen, et al.. (2025). Epigenetic and Transcriptional Programs Define Osteosarcoma Subtypes and Establish Targetable Vulnerabilities. Cancer Discovery. 16(2). 296–319. 1 indexed citations
3.
Nanda, Arjun S., Ke Wu, Iryna Irkliyenko, et al.. (2024). Direct transposition of native DNA for sensitive multimodal single-molecule sequencing. Nature Genetics. 56(6). 1300–1309. 8 indexed citations
4.
Lizardo, Michael M., Christopher S. Hughes, Alberto Delaidelli, et al.. (2024). Pharmacologic Inhibition of EIF4A Blocks NRF2 Synthesis to Prevent Osteosarcoma Metastasis. Clinical Cancer Research. 30(19). 4464–4481. 5 indexed citations
5.
Lee, Alex G., et al.. (2022). A 3D Osteosarcoma Model with Bone‐Mimicking Cues Reveals a Critical Role of Bone Mineral and Informs Drug Discovery. Advanced Healthcare Materials. 11(17). e2200768–e2200768. 13 indexed citations
6.
Solomon, Paige, Lisa L. Kirkemo, Gary M. Wilson, et al.. (2022). Discovery Proteomics Analysis Determines That Driver Oncogenes Suppress Antiviral Defense Pathways Through Reduction in Interferon-β Autocrine Stimulation. Molecular & Cellular Proteomics. 21(7). 100247–100247. 6 indexed citations
7.
Márquez, César, Kaja Kostyrko, Amanda Koehne, et al.. (2019). Antitumor activity of an engineered decoy receptor targeting CLCF1–CNTFR signaling in lung adenocarcinoma. Nature Medicine. 25(11). 1783–1795. 51 indexed citations
8.
Sayles, Leanne C., Amanda Koehne, Kieren D. Marini, et al.. (2019). Abstract 2880: Targeted drug therapies for osteosarcoma. Cancer Research. 79(13_Supplement). 2880–2880. 1 indexed citations
9.
Greenside, Peyton, Zoe Rogers, Jennifer J. Brady, et al.. (2017). Molecular definition of a metastatic lung cancer state reveals a targetable CD109–Janus kinase–Stat axis. Nature Medicine. 23(3). 291–300. 111 indexed citations
10.
Mitra, Siddhartha S., Sharareh Gholamin, Jens-Peter Volkmer, et al.. (2014). Abstract PR12: Overcoming immune evasion in pediatric hematologic and solid tumor malignancies: A preclinical study using a humanized anti-CD47 antibody. Cancer Research. 74(20_Supplement). PR12–PR12. 1 indexed citations
11.
Valdmanis, Paul N., Biswajoy Roy‐Chaudhuri, Leanne C. Sayles, et al.. (2013). Upregulation of the microRNA cluster at the Dlk1-Dio3 locus in lung adenocarcinoma. Oncogene. 34(1). 94–103. 41 indexed citations
12.
Zheng, Yanyan, Cecile C. de la Cruz, Leanne C. Sayles, et al.. (2013). A Rare Population of CD24+ITGB4+Notchhi Cells Drives Tumor Propagation in NSCLC and Requires Notch3 for Self-Renewal. Cancer Cell. 24(1). 59–74. 113 indexed citations
13.
Vicent, Silvestre, Leanne C. Sayles, Dedeepya Vaka, et al.. (2012). Cross-Species Functional Analysis of Cancer-Associated Fibroblasts Identifies a Critical Role for CLCF1 and IL-6 in Non–Small Cell Lung Cancer In Vivo. Cancer Research. 72(22). 5744–5756. 102 indexed citations
14.
Jaitin, Diego Adhemar, et al.. (2012). Abstract 1000: Oncogenic Kras inhibits mitochondrial metabolism by regulating the pyruvate dehydrogenase complex under conditions of nutrient stress. Cancer Research. 72(8_Supplement). 1000–1000. 1 indexed citations
15.
Graves, Edward E., Marta Vilalta, Ivana Cecić, et al.. (2010). Hypoxia in Models of Lung Cancer: Implications for Targeted Therapeutics. Clinical Cancer Research. 16(19). 4843–4852. 63 indexed citations
16.
Vicent, Silvestre, Chen Ron, Leanne C. Sayles, et al.. (2010). Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models. Journal of Clinical Investigation. 120(11). 3940–3952. 101 indexed citations
17.
Oliver, Trudy G., Kim L. Mercer, Leanne C. Sayles, et al.. (2010). Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer. Genes & Development. 24(8). 837–852. 7 indexed citations
18.
Grad, Leslie I., Leanne C. Sayles, & Bernard D. Lemire. (2007). Isolation and Functional Analysis of Mitochondria From the Nematode Caenorhabditis elegans. Methods in molecular biology. 372. 51–66. 28 indexed citations
19.
Gášková, Dana, et al.. (2007). Expression of Ndi1p, an alternative NADH:ubiquinone oxidoreductase, increases mitochondrial membrane potential in a C. elegans model of mitochondrial disease. Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1767(9). 1157–1163. 31 indexed citations
20.
Tsang, William Y.W., Leanne C. Sayles, Leslie I. Grad, David B. Pilgrim, & Bernard D. Lemire. (2001). Mitochondrial Respiratory Chain Deficiency inCaenorhabditis elegans Results in Developmental Arrest and Increased Life Span. Journal of Biological Chemistry. 276(34). 32240–32246. 118 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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