James Palacino

7.0k total citations · 3 hit papers
27 papers, 4.3k citations indexed

About

James Palacino is a scholar working on Molecular Biology, Physiology and Cellular and Molecular Neuroscience. According to data from OpenAlex, James Palacino has authored 27 papers receiving a total of 4.3k indexed citations (citations by other indexed papers that have themselves been cited), including 19 papers in Molecular Biology, 12 papers in Physiology and 9 papers in Cellular and Molecular Neuroscience. Recurrent topics in James Palacino's work include Nitric Oxide and Endothelin Effects (6 papers), Genetic Neurodegenerative Diseases (6 papers) and Alzheimer's disease research and treatments (4 papers). James Palacino is often cited by papers focused on Nitric Oxide and Endothelin Effects (6 papers), Genetic Neurodegenerative Diseases (6 papers) and Alzheimer's disease research and treatments (4 papers). James Palacino collaborates with scholars based in United States, China and Japan. James Palacino's co-authors include Richard A. Cohen, Soheil Najibi, Patrick J. Pagano, Victoria M. Bolotina, Jie Shen, Matthew S. Goldberg, Antonio J. Cayatte, Ran Cohen, Joachim Klose and Stefan Krauß and has published in prestigious journals such as Nature, Journal of Biological Chemistry and Journal of Clinical Oncology.

In The Last Decade

James Palacino

27 papers receiving 4.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle

1994 1.4k citations Victoria M. Bolotina, Soheil Najibi et al. Nature profile →
Mitochondrial Dysfunction and Oxidative Damage in parkin-deficient Mice

2004 787 citations James Palacino, Dijana Šagi et al. Journal of Biological Chemistry profile →
Parkin-deficient Mice Exhibit Nigrostriatal Deficits but Not Loss of Dopaminergic Neurons

2003 686 citations Matthew S. Goldberg, Sheila M. Fleming et al. Journal of Biological Chemistry profile →

Peers

Countries citing papers authored by James Palacino

Since Specialization

Citations

This map shows the geographic impact of James Palacino's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James Palacino with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James Palacino more than expected).

Fields of papers citing papers by James Palacino

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James Palacino. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James Palacino. The network helps show where James Palacino may publish in the future.

Co-authorship network of co-authors of James Palacino

This figure shows the co-authorship network connecting the top 25 collaborators of James Palacino. A scholar is included among the top collaborators of James Palacino based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with James Palacino. James Palacino is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	A phase 1, first-in-human, open label, escalation and expansion study of ORM-5029, a highly potent GSPT1 degrader targeting HER2, in patients with HER2-expressing advanced solid tumors. 2023 ·Journal of Clinical Oncology ·Sara A. Hurvitz, Erika Hamilton, Alexander I. Spira, Paula R. Pohlmann, Antonio Giordano, Katherine Clifton, Barry Anderson, Sujoy Dutta, (unknown), (unknown), James Palacino, (unknown), (unknown), Olaf Christensen, Sharon Wilks	15
2	Abstract 3933: ORM-5029: A first-in-class targeted protein degradation therapy using antibody neodegrader conjugate (AnDC) for HER2-expressing breast cancer 2022 ·Cancer Research ·James Palacino, (unknown), Yong Yi, Anna Skaletskaya, Khuloud Takrouri, Wesley P. Wong, Minsoo Kim, Dong-Ki Choi, (unknown), (unknown), (unknown), Pedro Lee, (unknown), (unknown), Jiyun Park, (unknown), Nathan Fishkin, Peter U. Park	19
3	High-Throughput Functional Analysis Distinguishes Pathogenic, Nonpathogenic, and Compensatory Transcriptional Changes in Neurodegeneration 2018 ·Cell Systems ·Ismael Al‐Ramahi, Boxun Lu, Simone Di Paola, Kaifang Pang, María de Haro, Ivana Peluso, Tatiana Gallego‐Flores, (unknown), (unknown), Benjamin Aaron Bleiberg, (unknown), (unknown), (unknown), (unknown), (unknown), Marc Hild, James Palacino, Zhandong Liu, Diego L. Medina, Juan Botas	28
4	Drugging unconventional targets: insights from Huntington's disease 2014 ·Trends in Pharmacological Sciences ·Shenliang Yu, (unknown), James Palacino, Marian DiFiglia, Boxun Lu	15
5	Identification of NUB1 as a suppressor of mutant Huntingtin toxicity via enhanced protein clearance 2013 ·Nature Neuroscience ·Boxun Lu, Ismael Al‐Ramahi, Antonio Valencia, Qiong Wang, Frada Berenshteyn, Haidi Yang, Tatiana Gallego‐Flores, (unknown), Arnaud Lacoste, Marc Hild, Marian DiFiglia, Juan Botas, James Palacino	83
6	A novel human embryonic stem cell‐derived Huntington's disease neuronal model exhibits mutant huntingtin (mHTT) aggregates and soluble mHTT‐dependent neurodegeneration 2013 ·The FASEB Journal ·Boxun Lu, James Palacino	67
7	Huntingtin cleavage product A forms in neurons and is reduced by gamma-secretase inhibitors 2010 ·Molecular Neurodegeneration ·Kimberly B. Kegel, Ellen Sapp, J. Steven Alexander, Patrick Reeves, Dorothée Bleckmann, (unknown), Nicholas Masso, Antonio Valencia, Hyunkyung Jeong, Dimitri Krainc, James Palacino, Daniel Curtis, Rainer Kühn, Claudia Betschart, Miguel Sena‐Esteves, Neil Aronin, Paolo Paganetti, Marian DiFiglia	16
8	Intrinsic resistance of neural stem cells to toxic metabolites may make them well suited for cell non‐autonomous disorders: evidence from a mouse model of Krabbe leukodystrophy 2006 ·Journal of Neurochemistry ·(unknown), Jean Pyo Lee, James Palacino, (unknown), Jianxue Li, Marie T. Vanier, David A. Wenger, Richard L. Sidman, Evan Y. Snyder	48
9	Mitochondrial Dysfunction and Oxidative Damage in parkin-deficient Mice breakdown → 2004 ·Journal of Biological Chemistry ·James Palacino, Dijana Šagi, Matthew S. Goldberg, Stefan Krauß, (unknown), Maik Wacker, Joachim Klose, Jie Shen	787
10	Parkin-deficient Mice Exhibit Nigrostriatal Deficits but Not Loss of Dopaminergic Neurons breakdown → 2003 ·Journal of Biological Chemistry ·Matthew S. Goldberg, Sheila M. Fleming, James Palacino, Carlos Cepeda, Hoa A. Lam, Anushree Bhatnagar, Edward G. Meloni, Nanping Wu, Larry C. Ackerson, Gloria J. Klapstein, Mahadevan Gajendiran, Bryan L. Roth, Marie-Françoise Chesselet, Nigel T. Maidment, Michael S. Levine, Jie Shen	686
11	Presenilin 1 Regulates β-Catenin-mediated Transcription in a Glycogen Synthase Kinase-3-independent Fashion 2001 ·Journal of Biological Chemistry ·James Palacino, Michael P. Murphy, Ohoshi Murayama, Katsunori Iwasaki, (unknown), Akihiko Takashima, Todd E. Golde, Benjamin Wolozin	29
12	Regulation of Apoptosis by Presenilin 1 1998 ·Neurobiology of Aging ·Benjamin Wolozin, (unknown), James Palacino	55
13	Direct association of presenilin‐1 with β‐catenin 1998 ·FEBS Letters ·Miyuki Murayama, Shoji Tanaka, James Palacino, Ohoshi Murayama, Toshiyuki Honda, Xiaoyan Sun, Kaori Yasutake, Naomi Nihonmatsu, Benjamin Wolozin, Akihiko Takashima	133
14	Production of pulmonary vasodilation by tolazoline, independent of nitric oxide production in neonatal lambs 1996 ·The Journal of Pediatrics ·Jerri Curtis, James Palacino, J. Timothy O’Neill	3
15	Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle breakdown → 1994 ·Nature ·Victoria M. Bolotina, Soheil Najibi, James Palacino, Patrick J. Pagano, Richard A. Cohen	1395
16	Chronic inhibition of nitric oxide production accelerates neointima formation and impairs endothelial function in hypercholesterolemic rabbits. 1994 ·Arteriosclerosis and Thrombosis A Journal of Vascular Biology ·Antonio J. Cayatte, James Palacino, (unknown), Ran Cohen	425
17	Potassium channel-mediated relaxation to acetylcholine in rabbit arteries. 1993 ·Journal of Pharmacology and Experimental Therapeutics ·Conrad L. Cowan, James Palacino, Soheil Najibi, Richard A. Cohen	104
18	Aldose Reductase Inhibition Restores Endothelial Cell Function in Diabetic Rabbit Aorta 1993 ·Journal of Cardiovascular Pharmacology ·Belay Tesfamariam, James Palacino, Robert M. Weisbrod, Richard A. Cohen	83
19	Chronic Inhibition of Nitric Oxide Production Augments Skin Vasoconstriction in the Rabbit Ear 1993 ·Journal of Cardiovascular Pharmacology ·Faisel Khan, James Palacino, Jay D. Coffman, Richard A. Cohen	17
20	Preservation of Endothelium-Dependent Relaxation in Atherosclerotic Rabbit Aorta by Probucol 1993 ·Journal of Cardiovascular Pharmacology ·Bernd Simon, Christian C. Haudenschild, Richard A. Cohen, James Palacino	53

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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