James N. Ihle

44.2k citations

286 papers · 37.5k indexed · 17 hit papers · h-index 100

Impact in

Immunology top 0.02%
- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
- interferon and immune responses
- Immune Response and Inflammation
Oncology top 0.02%
- Cytokine Signaling Pathways and Interactions

Papers in

Immunology 151
- Immune Cell Function and Interaction 58
- T-cell and Retrovirus Studies 35
- T-cell and B-cell Immunology 26
- Immune Response and Inflammation 21
- interferon and immune responses 21
Oncology 102
- Cytokine Signaling Pathways and Interactions 91

Co-authors: Bruce A. Witthuhn Frederick W. Quelle Ian M. Kerr Evan Parganas Demin Wang Olli Silvennoinen John L. Cleveland Gerard C. Grosveld
Journals: Molecular and Cellular Biology (49 papers)Virology (19 papers)Proceedings of the National Academy of Sciences (19 papers)Journal of Biological Chemistry (18 papers)The Journal of Immunology (17 papers)
Partner nations: United States Japan Germany

In The Last Decade

James N. Ihle

285 papers receiving 36.1k citations

Hit Papers

15 papers align trajectories log scale

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways 2003 · 727 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2003 Cancer Cell
2001 Current Opinion in Cell Biology
1998 Cell
1998 Cell
1996 Nature
1996 Cell
1996 Nature
1995 Science
1995 Nature
1995 Trends in Genetics
1994 Nature
1994 Science
1994 Science
1994 Trends in Biochemical Sciences
1994 Science
1993 The Lancet
1993 Cell

Peers

Countries citing papers authored by James N. Ihle

Since Specialization

Citations

This map shows the geographic impact of James N. Ihle's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James N. Ihle with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James N. Ihle more than expected).

Fields of papers citing papers by James N. Ihle

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James N. Ihle. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James N. Ihle. The network helps show where James N. Ihle may publish in the future.

Co-authors

The 25 scholars most cited alongside James N. Ihle, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with James N. Ihle Line = papers co-authored together James N. Ihle links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Re-examination of the Role of Suppressor of Cytokine Signaling 1 (SOCS1) in the Regulation of Toll-like Receptor Signaling Journal of Biological Chemistry ·Sébastien Gingras, Evan Parganas, Antoine De Pauw, James N. Ihle, Peter J. Murray	2004	114
2	Phospholipase Cγ2 Is Essential in the Functions of B Cell and Several Fc Receptors Immunity ·Demin Wang, Jian Feng, Renren Wen, Jean‐Christophe Marine, Mark Y. Sangster, Evan Parganas, Angelika Hoffmeyer, Carl W. Jackson, John L. Cleveland, Peter J. Murray, James N. Ihle	2000	390
3	Selective regulation ofBcl-X_Lby a Jak kinase-dependent pathway is bypassed in murine hematopoietic malignancies Genes & Development ·Graham Packham, Elsie White, Christine M. Eischen, Hui Yang, Evan Parganas, James N. Ihle, Didier Grillot, Gerard P. Zambetti, Gabriel Núñez, John L. Cleveland	1998	93
4	Chimeric Erythropoietin-Interferon γ Receptors Reveal Differences in Functional Architecture of Intracellular Domains for Signal Transduction Journal of Biological Chemistry ·Geetha Muthukumaran, Serguei V. Kotenko, Robert Donnelly, James N. Ihle, Sidney Pestka	1997	24
5	Jaks and stats in cytokine signaling Stem Cells ·James N. Ihle, Tetsuya Nosaka, William E. Thierfelder, Frederick W. Quelle, Kazuya Shimoda	1997	92
6	Interaction between the Components of the Interferon γ Receptor Complex Journal of Biological Chemistry ·Serguei V. Kotenko, Lara S. Izotova, Brian P. Pollack, Thomas M. Mariano, Robert Donnelly, Geetha Muthukumaran, Jeffry R. Cook, Gianni Garotta, Olli Silvennoinen, James N. Ihle, Sidney Pestka	1995	136
7	JAK2 Associates with the β _c Chain of the Receptor for Granulocyte-Macrophage Colony-Stimulating Factor, and Its Activation Requires the Membrane-Proximal Region Molecular and Cellular Biology ·Frederick W. Quelle, Noriko Sato, Bruce A. Witthuhn, Roger Inhorn, Matthias Eder, Atsushi Miyajima, James D. Griffin, James N. Ihle	1994	83
8	Tec Kinase Associates with c-kit and Is Tyrosine Phosphorylated and Activated following Stem Cell Factor Binding Molecular and Cellular Biology ·Bo Tang, Hiroyuki Mano, Taolin Yi, James N. Ihle	1994	91
9	Interaction of IL-2Rβ and γ _c Chains with Jak1 and Jak3: Implications for XSCID and XCID Science ·Sarah M. Russell, James A. Johnston, Masayuki Noguchi, Masaru Kawamura, Chris M. Bacon, Michael Friedmann, Maria Berg, Daniel W. McVicar, Bruce A. Witthuhn, Olli Silvennoinen, Armond S. Goldman, Frank C. Schmalstieg, James N. Ihle, John J. O’Shea, Warren J. Leonard Hit paper breakdown →	1994	553
10	Disposition of recombinant human granulocyte colony-stimulating factor in children with severe chronic neutropenia The Journal of Pediatrics ·Christine M. Kearns, Winfred C. Wang, Norbert Stute, James N. Ihle, William E. Evans	1993	47
11	Four of the Seven Zinc Fingers of the Evi-1 Myeloid-Transforming Gene Are Required for Sequence-Specific Binding to GA(C/T)AAGA(T/C)AAGATAA Molecular and Cellular Biology ·Ruud Delwel, T. Funabiki, Brent L. Kreider, Kazuhiro Morishita, James N. Ihle	1993	106
12	Interferon-induced nuclear signalling by Jak protein tyrosine kinases Nature ·Olli Silvennoinen, James N. Ihle, Joseph Schlessinger, David T. Levy	1993	323
13	Retroviral Insertions 90 Kilobases Proximal to the Evi-1 Myeloid Transforming Gene Activate Transcription from the Normal Promoter Molecular and Cellular Biology ·Christopher Bartholomew, James N. Ihle	1991	66
14	Induction of Tyrosine Phosphorylation by the Erythropoietin Receptor Correlates with Mitogenesis Molecular and Cellular Biology ·Osamu Miura, Alan D. D’Andrea, David Kabat, James N. Ihle	1991	47
15	Identification of a Common Ecotropic Viral Integration Site, Evi-1 , in the DNA of AKXD Murine Myeloid Tumors Molecular and Cellular Biology ·Michael L. Mucenski, Benjamin A. Taylor, James N. Ihle, Janet W. Hartley, Herbert C. Morse, Nancy A. Jenkins, Neal G. Copeland	1988	51
16	Retroviral activation of a novel gene encoding a zinc finger protein in IL-3-dependent myeloid leukemia cell lines Cell ·Kazuhiro Morishita, Diana S. Parker, Michael L. Mucenski, Nancy A. Jenkins, Neal G. Copeland, James N. Ihle	1988	362
17	raf Family Serine/Threonine Protein Kinases in Mitogen Signal Transduction Cold Spring Harbor Symposia on Quantitative Biology ·Ulf R. Rapp, Gisela Heidecker, Mahmoud Huleihel, John L. Cleveland, Woo-Young Choi, Tony Pawson, James N. Ihle, Wayne B. Anderson	1988	103
18	Detection of c- rel -Related Transcripts in Mouse Hematopoietic Tissues, Fractionated Lymphocyte Populations, and Cell Lines Molecular and Cellular Biology ·Elise Brownell, Bonnie J. Mathieson, Howard A. Young, JR Keller, James N. Ihle, Nancy R. Rice	1987	10
19	Autogenous immunity to mouse mammary tumor virus in mouse strains of high and low mammary tumor incidence. Munich Personal RePEc Archive (Ludwig Maximilian University of Munich) ·James N. Ihle, Larry O. Arthur, Donald L. Fine	1976	29
20	Autogenous immunity to endogenous RNA tumor virus: humoral immune response to virus envelope antigens. Munich Personal RePEc Archive (Ludwig Maximilian University of Munich) ·Michael G. Hanna, James N. Ihle, J. C. Lee	1976	5

About James N. Ihle

James N. Ihle is a scholar working on Immunology, Oncology, Hematology, Pharmacology and Genetics, having authored 286 papers that have together received 37.5k indexed citations. Recurring topics across this work include Cytokine Signaling Pathways and Interactions (91 papers), Immune Cell Function and Interaction (58 papers), Virus-based gene therapy research (54 papers), T-cell and Retrovirus Studies (35 papers), T-cell and B-cell Immunology (26 papers), Immune Response and Inflammation (21 papers), Monoclonal and Polyclonal Antibodies Research (21 papers) and interferon and immune responses (21 papers). The work is most often cited by research in Immunology (17.9k citations), Oncology (16.8k citations), Hematology (5.0k citations), Genetics (3.1k citations) and Pharmacology (2.4k citations). James N. Ihle has collaborated with scholars based in United States, Japan and Germany. Frequent co-authors include Bruce A. Witthuhn, Frederick W. Quelle, Ian M. Kerr, Evan Parganas, Demin Wang, Olli Silvennoinen, John L. Cleveland, Gerard C. Grosveld, William E. Thierfelder and T Yi. Their work appears in journals such as Molecular and Cellular Biology, Virology, Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and The Journal of Immunology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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