Brian F. O’Dowd

24.4k citations

187 papers · 19.2k indexed · 8 hit papers · h-index 78

Molecular Biology top 0.2%
Cellular and Molecular Neuroscience top 0.05%
Pharmacology top 0.1%
Surgery top 1%
Physiology top 1%

Co-authors: Susan R. George Tuan Nguyen Regina Cheng Robert J. Lefkowitz Marc G. Caron Samuel P. Lee Philip Seeman Michel Bouvier
Topics: Receptor Mechanisms and Signaling (137 papers)Neuropeptides and Animal Physiology (79 papers)Neurotransmitter Receptor Influence on Behavior (64 papers)
Cited by: Cellular and Molecular Neuroscience Endocrine and Autonomic Systems Molecular Biology
Journals: Nature Proceedings of the National Academy of Sciences Nucleic Acids Research
Partner nations: Canada United States Germany

In The Last Decade

Brian F. O’Dowd

187 papers receiving 18.8k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1

1991 947 citations Roger K. Sunahara, Brian F. O’Dowd et al. profile →
A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11

1993 723 citations Brian F. O’Dowd, Susan R. George et al. Gene profile →
Characterization of Apelin, the Ligand for the APJ Receptor

2000 587 citations Dennis K. Lee, Regina Cheng et al. profile →
Palmitoylation of the human β2-adrenergic receptor

1989 511 citations Brian F. O’Dowd et al. Journal of Biological Chemistry profile →
Removal of phosphorylation sites from the β2-adrenergic receptor delays onset of agonist-promoted desensitization

1988 370 citations Brian F. O’Dowd et al. profile →
Phosphorylation Sites on Two Domains of the β2-Adrenergic Receptor Are Involved in Distinct Pathways of Receptor Desensitization

1989 357 citations Brian F. O’Dowd et al. Journal of Biological Chemistry profile →
Site-directed mutagenesis of the cytoplasmic domains of the human beta 2-adrenergic receptor. Localization of regions involved in G protein-receptor coupling.

1988 337 citations Brian F. O’Dowd et al. Journal of Biological Chemistry profile →
Two distinct pathways for cAMP-mediated down-regulation of the β2-adrenergic receptor

1989 239 citations Brian F. O’Dowd et al. Journal of Biological Chemistry profile →

Peers

Countries citing papers authored by Brian F. O’Dowd

Since Specialization

Citations

This map shows the geographic impact of Brian F. O’Dowd's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Brian F. O’Dowd with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Brian F. O’Dowd more than expected).

Fields of papers citing papers by Brian F. O’Dowd

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Brian F. O’Dowd. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Brian F. O’Dowd. The network helps show where Brian F. O’Dowd may publish in the future.

Co-authorship network of co-authors of Brian F. O’Dowd

This figure shows the co-authorship network connecting the top 25 collaborators of Brian F. O’Dowd. A scholar is included among the top collaborators of Brian F. O’Dowd based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Brian F. O’Dowd. Brian F. O’Dowd is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Heteromeric Dopamine Receptor Signaling Complexes: Emerging Neurobiology and Disease Relevance 2013 ·Neuropsychopharmacology ·Melissa L. Perreault,Ahmed Hasbi,Brian F. O’Dowd,Susan R. George	128
2	Separation and reformation of cell surface dopamine receptor oligomers visualized in cells 2011 ·European Journal of Pharmacology ·Brian F. O’Dowd,Ji X,Mohammad Alijaniaram,Tuan Nguyen,Susan R. George	14
3	The fate of the internalized apelin receptor is determined by different isoforms of apelin mediating differential interaction with β-arrestin 2010 ·Biochemical and Biophysical Research Communications ·Dennis K. Lee,Stephen S. G. Ferguson,Susan R. George,Brian F. O’Dowd	77
4	Calcium signaling cascade links dopamine D1–D2 receptor heteromer to striatal BDNF production and neuronal growth 2009 ·Proceedings of the National Academy of Sciences ·Ahmed Hasbi,Theresa Fan,Mohammad Alijaniaram,Tuan Nguyen,Melissa L. Perreault,Brian F. O’Dowd,Susan R. George	214
5	Using Ligand-Induced Conformational Change to Screen for Compounds Targeting G-Protein-Coupled Receptors 2007 ·SLAS DISCOVERY ·Brian F. O’Dowd,Mohammad Alijaniaram,Ji X,Tuan Nguyen,Richard M. Eglen,Susan R. George	12
6	Neuronal Gq/11-coupled dopamine receptors: an uncharted role for dopamine 2007 ·Trends in Pharmacological Sciences ·Asim J. Rashid,Brian F. O’Dowd,Vaneeta Verma,Sarah J. George	69
7	D1–D2 dopamine receptor heterooligomers with unique pharmacology are coupled to rapid activation of G _q /11 in the striatum 2006 ·Proceedings of the National Academy of Sciences ·Asim J. Rashid,Christopher H. So,Michael M. C. Kong,(unknown),Mufida El-Ghundi,Regina Cheng,Brian F. O’Dowd,Susan R. George	379
8	G protein-coupled receptor-protein interactions 2005 ·Susan R. George,Brian F. O’Dowd	22
9	Minireview: Diversity and Complexity of Signaling through Peptidergic G Protein-Coupled Receptors 2004 ·Endocrinology ·Asim J. Rashid,Brian F. O’Dowd,Susan R. George	44
10	Attenuation of sucrose reinforcement in dopamine D₁ receptor deficient mice 2003 ·European Journal of Neuroscience ·Mufida El-Ghundi,Brian F. O’Dowd,(unknown),Susan R. George	59
11	Distinct Residues in the Carboxyl Tail Mediate Agonist-induced Desensitization and Internalization of the Human Dopamine D1 Receptor 2002 ·Journal of Biological Chemistry ·(unknown),Miles D. Thompson,George Varghese,(unknown),(unknown),Susan R. George,Brian F. O’Dowd	57
12	FMRFamide-Related Neuropeptides Are Agonists of the Orphan G-Protein-Coupled Receptor GPR54 2001 ·Biochemical and Biophysical Research Communications ·Michelle K. Clements,Terrence P. McDonald,Ruiping Wang,Guochun Xie,Brian F. O’Dowd,Susan R. George,Christopher P. Austin,Qingyun Liu	96
13	Discovery and mapping of ten novel G protein-coupled receptor genes 2001 ·Gene ·Dennis K. Lee,Tuan Nguyen,Kevin R. Lynch,Regina Cheng,William B. Vanti,(unknown),(unknown),Jilly F. Evans,Susan R. George,Brian F. O’Dowd	170
14	Human dopamine transporter gene: coding region conservation among normal, Tourette's disorder, alcohol dependence and attention-deficit hyperactivity disorder populations 2000 ·Molecular Psychiatry ·David J. Vandenbergh,Miles D. Thompson,Edwin H. Cook,(unknown),Nguyen Hoang Khue Tu,Matthew D. Krasowski,(unknown),David E. Comings,Edward M. Sellers,Rachel F. Tyndale,Susan R. George,Brian F. O’Dowd,George R. Uhl	112
15	Serotonin 5‐HT_1B and 5‐HT_1D receptors form homodimers when expressed alone and heterodimers when co‐expressed 1999 ·FEBS Letters ·Zhidong Xie,Samuel P. Lee,Brian F. O’Dowd,Susan R. George	94
16	A Serotonin Receptor Gene (5HT1A) Variant Found in a Tourette's Syndrome Patient 1996 ·Biochemical and Biophysical Research Communications ·(unknown),Yang Shen,Tuan Nguyen,Terri Messier,Mark R. Brann,David E. Comings,Susan R. George,Brian F. O’Dowd	40
17	Dopamine D1 Receptor Mutagenesis: Role of Amino Acids in Agonist and Antagonist Binding 1993 ·Biochemical and Biophysical Research Communications ·Mirko Tomić,Philip Seeman,Susan R. George,Brian F. O’Dowd	35
18	Polymorphisms of the D4 Dopamine Receptor Alleles in Chronic Alcoholism 1993 ·Biochemical and Biophysical Research Communications ·Susan R. George,(unknown),Tuan Nguyen,Yedy Israel,Brian F. O’Dowd	72
19	Transcription of a human dopamine D5 pseudogene 1991 ·Biochemical and Biophysical Research Communications ·Tuan Nguyen,Roger K. Sunahara,Adriano Marchese,Hubert H.M. Van Tol,Philip Seeman,Brian F. O’Dowd	29
20	Cloning of two additional catecholamine receptors from rat brain 1990 ·FEBS Letters ·Brian F. O’Dowd,Tuan Nguyen,(unknown),Keith R. Jarvie,Yedy Israel,Philip Seeman,Hyman B. Niznik	42

About Brian F. O’Dowd

Brian F. O’Dowd is a scholar working on Cellular and Molecular Neuroscience, Molecular Biology and Endocrine and Autonomic Systems, having authored 187 papers that have together received 19.2k indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (137 papers), Neuropeptides and Animal Physiology (79 papers) and Neurotransmitter Receptor Influence on Behavior (64 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (11.1k citations), Endocrine and Autonomic Systems (1.3k citations) and Molecular Biology (11.7k citations). Brian F. O’Dowd has collaborated with scholars based in Canada, United States and Germany. Frequent co-authors include Susan R. George, Tuan Nguyen, Regina Cheng, Robert J. Lefkowitz, Marc G. Caron, Samuel P. Lee, Philip Seeman, Michel Bouvier, Gordon Ng and Theresa Fan. Their work appears in journals such as Nature, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact