Samuel N. Young

4.6k total citations · 1 hit paper
29 papers, 1.9k citations indexed

About

Samuel N. Young is a scholar working on Molecular Biology, Cell Biology and Immunology. According to data from OpenAlex, Samuel N. Young has authored 29 papers receiving a total of 1.9k indexed citations (citations by other indexed papers that have themselves been cited), including 26 papers in Molecular Biology, 11 papers in Cell Biology and 9 papers in Immunology. Recurrent topics in Samuel N. Young's work include Cell death mechanisms and regulation (20 papers), Hippo pathway signaling and YAP/TAZ (9 papers) and CRISPR and Genetic Engineering (7 papers). Samuel N. Young is often cited by papers focused on Cell death mechanisms and regulation (20 papers), Hippo pathway signaling and YAP/TAZ (9 papers) and CRISPR and Genetic Engineering (7 papers). Samuel N. Young collaborates with scholars based in Australia, United States and New Zealand. Samuel N. Young's co-authors include James M. Murphy, Isabelle S. Lucet, Joanne M. Hildebrand, Peter E. Czabotar, John Silke, Maria C. Tanzer, Jeffrey J. Babon, Andrew I. Webb, Guillaume Lessène and Warren S. Alexander and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Nature Communications and The EMBO Journal.

In The Last Decade

Samuel N. Young

27 papers receiving 1.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death

2014 468 citations Joanne M. Hildebrand, Maria C. Tanzer et al. profile →

Peers

Countries citing papers authored by Samuel N. Young

Since Specialization

Citations

This map shows the geographic impact of Samuel N. Young's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Samuel N. Young with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Samuel N. Young more than expected).

Fields of papers citing papers by Samuel N. Young

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Samuel N. Young. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Samuel N. Young. The network helps show where Samuel N. Young may publish in the future.

Co-authorship network of co-authors of Samuel N. Young

This figure shows the co-authorship network connecting the top 25 collaborators of Samuel N. Young. A scholar is included among the top collaborators of Samuel N. Young based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Samuel N. Young. Samuel N. Young is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	The kinase domain of RIPK3 tunes its scaffolding functions 2026 ·Cell Death and Differentiation ·(unknown), Christopher R. Horne, (unknown), Adele Preaudet, (unknown), Samuel N. Young, (unknown), Sarah E. Garnish, Anne Hempel, Cathrine Hall, Joanne M. Hildebrand, (unknown), (unknown), Tracy L. Putoczki, Edwin D. Hawkins, (unknown), James M. Murphy	0
2	Inhibitors identify an auxiliary role for mTOR signalling in necroptosis execution downstream of MLKL activation 2024 ·Biochemical Journal ·Sarah E. Garnish, Christopher R. Horne, Yanxiang Meng, Samuel N. Young, Annette V. Jacobsen, Joanne M. Hildebrand, James M. Murphy	2
3	Co-clustering of EphB6 and ephrinB1 in trans restrains cancer cell invasion 2024 ·Communications Biology ·Lung‐Yu Liang, Niall D. Geoghegan, Michael J. Mlodzianoski, Andrew Leis, Lachlan Whitehead, (unknown), Samuel N. Young, Peter W. Janes, (unknown), Debnath Ghosal, Kelly L. Rogers, James M. Murphy, Isabelle S. Lucet	1
4	Phosphorylation-dependent pseudokinase domain dimerization drives full-length MLKL oligomerization 2023 ·Nature Communications ·Yanxiang Meng, Sarah E. Garnish, Katherine A. Davies, (unknown), Andrew Leis, Christopher R. Horne, Joanne M. Hildebrand, (unknown), Cheree Fitzgibbon, Samuel N. Young, Toby A. Dite, Laura F. Dagley, Aarya Venkat, Natarajan Kannan, Akiko Koide, Shohei Koide, Alisa Glukhova, Peter E. Czabotar, James M. Murphy	22
5	Human RIPK3 C-lobe phosphorylation is essential for necroptotic signaling 2022 ·Cell Death and Disease ·Yanxiang Meng, Christopher R. Horne, André L. Samson, Laura F. Dagley, Samuel N. Young, Jarrod J. Sandow, Peter E. Czabotar, James M. Murphy	19
6	Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis 2021 ·Nature Communications ·Yanxiang Meng, Katherine A. Davies, Cheree Fitzgibbon, Samuel N. Young, Sarah E. Garnish, Christopher R. Horne, Cindy S. Luo, Jean‐Marc Garnier, Lung‐Yu Liang, Angus D. Cowan, André L. Samson, Guillaume Lessène, Jarrod J. Sandow, Peter E. Czabotar, James M. Murphy	67
7	A toolbox for imaging RIPK1, RIPK3, and MLKL in mouse and human cells 2021 ·Cell Death and Differentiation ·André L. Samson, Cheree Fitzgibbon, (unknown), Joanne M. Hildebrand, Lachlan Whitehead, (unknown), Annette V. Jacobsen, Christopher R. Horne, (unknown), Samuel N. Young, Kelly L. Rogers, Edwin D. Hawkins, James M. Murphy	43
8	Granulovirus PK-1 kinase activity relies on a side-to-side dimerization mode centered on the regulatory αC helix 2021 ·Nature Communications ·Michael R. Oliver, Christopher R. Horne, Safal Shrestha, J.R. Keown, Lung‐Yu Liang, Samuel N. Young, Jarrod J. Sandow, Andrew I. Webb, David C. Goldstone, Isabelle S. Lucet, Natarajan Kannan, Peter Metcalf, James M. Murphy	5
9	Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis 2021 ·Nature Communications ·Sarah E. Garnish, Yanxiang Meng, Akiko Koide, Jarrod J. Sandow, (unknown), Annette V. Jacobsen, Wayland Yeung, André L. Samson, Christopher R. Horne, Cheree Fitzgibbon, Samuel N. Young, (unknown), Andrew I. Webb, Emma J. Petrie, Joanne M. Hildebrand, Natarajan Kannan, Peter E. Czabotar, Shohei Koide, James M. Murphy	70
10	Oligomerization‐driven MLKL ubiquitylation antagonizes necroptosis 2021 ·The EMBO Journal ·Zikou Liu, Laura F. Dagley, Kristy Shield‐Artin, Samuel N. Young, Aleksandra Bankovacki, (unknown), Michelle Tang, Jason Howitt, Che A. Stafford, Ueli Nachbur, Cheree Fitzgibbon, Sarah E. Garnish, Andrew I. Webb, David Komander, James M. Murphy, Joanne M. Hildebrand, John Silke	49
11	Crystal structure of the hinge domain of Smchd1 reveals its dimerization mode and nucleic acid–binding residues 2020 ·Science Signaling ·Kelan Chen, Richard W. Birkinshaw, (unknown), (unknown), Ruoyun Wang, Megan Iminitoff, Jarrod J. Sandow, Samuel N. Young, Patrick J. Hennessy, Tracy A. Willson, (unknown), Andrew I. Webb, Marnie E. Blewitt, Peter E. Czabotar, James M. Murphy	12
12	Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues 2020 ·Nature Communications ·Katherine A. Davies, Cheree Fitzgibbon, Samuel N. Young, Sarah E. Garnish, Wayland Yeung, (unknown), Richard W. Birkinshaw, Jarrod J. Sandow, (unknown), Lung‐Yu Liang, Isabelle S. Lucet, James D. Chalmers, Wayne M. Patrick, Natarajan Kannan, Emma J. Petrie, Peter E. Czabotar, James M. Murphy	45
13	Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3 2019 ·Cell Reports ·Emma J. Petrie, Jarrod J. Sandow, (unknown), Lung‐Yu Liang, (unknown), Samuel N. Young, Wilhelmus J. A. Kersten, Cheree Fitzgibbon, André L. Samson, Annette V. Jacobsen, Kym N. Lowes, Amanda E. Au, Hélène Jousset Sabroux, Najoua Lalaoui, Andrew I. Webb, Guillaume Lessène, Gerard Manning, Isabelle S. Lucet, James M. Murphy	88
14	The brace helices of MLKL mediate interdomain communication and oligomerisation to regulate cell death by necroptosis 2018 ·Cell Death and Differentiation ·Katherine A. Davies, Maria C. Tanzer, Michael D. W. Griffin, (unknown), Samuel N. Young, Rui Qin, Emma J. Petrie, Peter E. Czabotar, John Silke, James M. Murphy	73
15	Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis 2018 ·Nature Communications ·Emma J. Petrie, Jarrod J. Sandow, Annette V. Jacobsen, Brian J. Smith, Michael D. W. Griffin, Isabelle S. Lucet, Weiwen Dai, Samuel N. Young, Maria C. Tanzer, Ahmad Z. Wardak, Lung‐Yu Liang, Angus D. Cowan, Joanne M. Hildebrand, Wilhelmus J. A. Kersten, Guillaume Lessène, John Silke, Peter E. Czabotar, Andrew I. Webb, James M. Murphy	147
16	Evolutionary divergence of the necroptosis effector MLKL 2016 ·Cell Death and Differentiation ·Maria C. Tanzer, (unknown), Joanne M. Hildebrand, Samuel N. Young, Ahmad Z. Wardak, Anne Tripaydonis, Emma J. Petrie, (unknown), David L. Vaux, James E. Vince, Peter E. Czabotar, John Silke, James M. Murphy	92
17	Functional characterization of c-Mpl ectodomain mutations that underlie congenital amegakaryocytic thrombocytopenia 2014 ·Growth Factors ·Leila N. Varghese, Jian‐Guo Zhang, Samuel N. Young, Tracy A. Willson, Warren S. Alexander, Nicos A. Nicola, Jeffrey J. Babon, James M. Murphy	13
18	RIPK1- and RIPK3-induced cell death mode is determined by target availability 2014 ·Cell Death and Differentiation ·W D Cook, Donia M. Moujalled, (unknown), Peter Lock, Samuel N. Young, James M. Murphy, David L. Vaux	122
19	Mechanistic insights into activation and SOCS3-mediated inhibition of myeloproliferative neoplasm-associated JAK2 mutants from biochemical and structural analyses 2013 ·Biochemical Journal ·Leila N. Varghese, Daniela Ungureanu, Nicholas P. D. Liau, Samuel N. Young, Artem Laktyushin, Henrik M. Hammarén, Isabelle S. Lucet, Nicos A. Nicola, Olli Silvennoinen, Jeffrey J. Babon, James M. Murphy	30
20	Suppression of Cytokine Signaling by SOCS3: Characterization of the Mode of Inhibition and the Basis of Its Specificity 2012 ·Immunity ·Jeffrey J. Babon, Nadia J. Kershaw, James M. Murphy, Leila N. Varghese, Artem Laktyushin, Samuel N. Young, Isabelle S. Lucet, Raymond S. Norton, Nicos A. Nicola	212

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact