Ian Irwin

13.0k total citations · 3 hit papers
86 papers, 10.2k citations indexed

About

Ian Irwin is a scholar working on Neurology, Cellular and Molecular Neuroscience and Physiology. According to data from OpenAlex, Ian Irwin has authored 86 papers receiving a total of 10.2k indexed citations (citations by other indexed papers that have themselves been cited), including 52 papers in Neurology, 49 papers in Cellular and Molecular Neuroscience and 13 papers in Physiology. Recurrent topics in Ian Irwin's work include Parkinson's Disease Mechanisms and Treatments (51 papers), Neuroscience and Neuropharmacology Research (31 papers) and Neurotransmitter Receptor Influence on Behavior (16 papers). Ian Irwin is often cited by papers focused on Parkinson's Disease Mechanisms and Treatments (51 papers), Neuroscience and Neuropharmacology Research (31 papers) and Neurotransmitter Receptor Influence on Behavior (16 papers). Ian Irwin collaborates with scholars based in United States, Sweden and United Kingdom. Ian Irwin's co-authors include J. William Langston, James W. Tetrud, Philip L. Ballard, J. William Langston, Lysia S. Forno, Louis E. DeLanney, L.E. DeLanney, Donato A. Di Monte, Charles S. Rebert and G.A. Ricaurte and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Neuron.

In The Last Decade

Ian Irwin

85 papers receiving 10.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Chronic Parkinsonism in Humans Due to a Product of Meperidine-Analog Synthesis

1983 3.6k citations J. William Langston, Ian Irwin et al. profile →
Selective nigral toxicity after systemic administration of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyrine (MPTP) in the squirrel monkey

1984 740 citations J. William Langston, Lysia S. Forno et al. Brain Research profile →
Pargyline Prevents MPTP-Induced Parkinsonism in Primates

1984 492 citations J. William Langston, Ian Irwin et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Ian Irwin United States	43	6.6k	5.9k	2.1k	1.3k	1.2k	86	10.2k
Richard E. Heikkila United States	50	5.1k 0.8×	6.3k 1.1×	3.6k 1.7×	828 0.7×	1.4k 1.2×	136	11.7k
Chuang C. Chiueh United States	49	3.8k 0.6×	4.3k 0.7×	2.3k 1.1×	764 0.6×	1.6k 1.4×	120	8.7k
Patricia K. Sonsalla United States	46	2.9k 0.4×	4.2k 0.7×	1.8k 0.9×	758 0.6×	651 0.6×	98	6.7k
Donato A. Di Monte United States	67	7.2k 1.1×	5.1k 0.9×	3.7k 1.7×	2.1k 1.7×	2.7k 2.3×	167	13.7k
J. William Langston United States	39	4.1k 0.6×	3.1k 0.5×	1.2k 0.6×	823 0.7×	617 0.5×	78	6.3k
Teresa G. Hastings United States	41	3.0k 0.4×	3.2k 0.5×	2.7k 1.3×	918 0.7×	1.2k 1.0×	54	7.2k
Micaela Morelli Italy	50	3.1k 0.5×	5.7k 1.0×	3.0k 1.4×	734 0.6×	664 0.6×	236	9.6k
F. Javoy‐Agid France	49	5.2k 0.8×	5.2k 0.9×	3.3k 1.5×	1.6k 1.3×	1.9k 1.6×	109	10.4k
Fabio Blandini Italy	50	3.6k 0.5×	3.0k 0.5×	2.0k 0.9×	1.2k 1.0×	1.5k 1.3×	174	7.9k
James W. Tetrud United States	23	4.8k 0.7×	3.5k 0.6×	1.7k 0.8×	1.1k 0.8×	765 0.7×	34	7.0k

Countries citing papers authored by Ian Irwin

Since Specialization

Citations

This map shows the geographic impact of Ian Irwin's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ian Irwin with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ian Irwin more than expected).

Fields of papers citing papers by Ian Irwin

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ian Irwin. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ian Irwin. The network helps show where Ian Irwin may publish in the future.

Co-authorship network of co-authors of Ian Irwin

This figure shows the co-authorship network connecting the top 25 collaborators of Ian Irwin. A scholar is included among the top collaborators of Ian Irwin based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ian Irwin. Ian Irwin is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

McGrath, Patrick J., Maryam Akbari‐Fakhrabadi, William F. Chaplin, et al.. (2025). Development and Evaluation of the Firefighter Exposure to Carcinogens Scale. Journal of Occupational and Environmental Medicine. 67(11). e821–e826.

Bavisotto, Linda M., David Ellis, Peter G. Milner, et al.. (2010). Tecarfarin, a Novel Vitamin K Reductase Antagonist, Is Not Affected by CYP2C9 and CYP3A4 Inhibition Following Concomitant Administration of Fluconazole in Healthy Participants. The Journal of Clinical Pharmacology. 51(4). 561–574. 23 indexed citations

Choppin, Agnès, Ian Irwin, Lei Shao, et al.. (2009). Effect of tecarfarin, a novel vitamin K epoxide reductase inhibitor, on coagulation in beagle dogs. British Journal of Pharmacology. 158(6). 1536–1547. 17 indexed citations

Pulliam, Lynn, Ian Irwin, Leonard Kusdra, et al.. (2001). CPI-1189 attenuates effects of suspected neurotoxins associated with AIDS dementia: a possible role for ERK activation. Brain Research. 893(1-2). 95–103. 16 indexed citations

Yee, Randa E., Ian Irwin, D. B. Stout, et al.. (2001). Novel observations with FDOPA‐PET imaging after early nigrostriatal damage. Movement Disorders. 16(5). 838–848. 32 indexed citations

Irwin, Ian, et al.. (1996). GDNF Induces a Dystonia-like State in Neonatal Rats and Stimulates Dopamine and Serotonin Synthesis. Neuron. 16(3). 665–673. 68 indexed citations

Chan, Piu, Donato A. Di Monte, Jin Jun Luo, et al.. (1994). Rapid ATP Loss Caused by Methamphetamine in the Mouse Striatum: Relationship Between Energy Impairment and Dopaminergic Neurotoxicity. Journal of Neurochemistry. 62(6). 2484–2487. 115 indexed citations

Monte, Donato A. Di, Ellen Y. Wu, Ian Irwin, Louis E. DeLanney, & J. William Langston. (1992). Production and disposition of 1‐methyl‐4‐phenylpyridinium in primary cultures of mouse astrocytes. Glia. 5(1). 48–55. 18 indexed citations

Irwin, Ian, Kevin T. Finnegan, Louis E. DeLanney, Donato A. Di Monte, & J. William Langston. (1992). The relationships between aging, monoamine oxidase, striatal dopamine and the effects of MPTP in C57BL/6 mice: a critical reassessment. Brain Research. 572(1-2). 224–231. 78 indexed citations

10.

Chan, Piu, Louis E. DeLanney, Ian Irwin, J. William Langston, & Donato A. Di Monte. (1991). Rapid ATP Loss Caused by 1‐Methyl‐4‐Phenyl‐1,2,3,6‐Tetrahydropyridine in Mouse Brain. Journal of Neurochemistry. 57(1). 348–351. 192 indexed citations

11.

Segal, Ira S., Ian Irwin, Louis E. DeLanney, et al.. (1990). Modulating role of dopamine on anesthetic requirements. European Journal of Pharmacology. 186(1). 9–15. 21 indexed citations

12.

Irwin, Ian, Louis E. DeLanney, Lysia S. Forno, et al.. (1990). The evolution of nigrostriatal neurochemical changes in the MPTP-treated squirrel monkey. Brain Research. 531(1-2). 242–252. 50 indexed citations

13.

Ricaurte, G.A., Kevin T. Finnegan, Ian Irwin, & J. William Langston. (1990). Aminergic Metabolites in Cerebrospinal Fluid of Humans Previously Exposed to MDMA: Preliminary Observations^a. Annals of the New York Academy of Sciences. 600(1). 699–708. 78 indexed citations

14.

Ricaurte, G.A., L.E. DeLanney, Ian Irwin, et al.. (1989). Evaluation of the neurotoxic potential of N,N-dimethylamphetamine: an illicit analog of methamphetamine. Brain Research. 490(2). 301–306. 15 indexed citations

15.

Monte, Donato A. Di, et al.. (1989). Diethyldithiocarbamate and disulfiram inhibit MPP+ and dopamine uptake by striatal synaptosomes. European Journal of Pharmacology. 166(1). 23–29. 6 indexed citations

16.

Irwin, Ian, Louis E. DeLanney, Donato A. Di Monte, & J. William Langston. (1989). The biodisposition of MPP+ in mouse brain. Neuroscience Letters. 101(1). 83–88. 26 indexed citations

17.

Ricaurte, G.A., L.E. DeLanney, Sandra G. Wiener, Ian Irwin, & J. William Langston. (1988). 5-Hydroxyindoleacetic acid in cerebrospinal fluid reflects serotonergic damage induced by 3,4-methylenedioxymethamphetamine in CNS of non-human primates. Brain Research. 474(2). 359–363. 73 indexed citations

18.

Notter, Mary F.D., Ian Irwin, J. William Langston, & Don M. Gash. (1988). Neurotoxicity of MPTP and MPP+ in vitro: characterization using specific cell lines. Brain Research. 456(2). 254–262. 21 indexed citations

19.

Irwin, Ian, George A. Ricaurte, Louis E. DeLanney, & J. William Langston. (1988). The sensitivity of nigrostriatal dopamine neurons to MPP+ does not increase with age. Neuroscience Letters. 87(1-2). 51–56. 20 indexed citations

20.

Irwin, Ian, Ellen Y. Wu, Louis E. DeLanney, Anthony J. Trevor, & J. William Langston. (1987). The effect of diethyldithiocarbamate on the biodisposition of MPTP: an explanation for enhanced neurotoxicity. European Journal of Pharmacology. 141(2). 209–217. 41 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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