Matthew P. Frosch

69.7k total citations · 16 hit papers
299 papers, 32.3k citations indexed

About

Matthew P. Frosch is a scholar working on Physiology, Neurology and Molecular Biology. According to data from OpenAlex, Matthew P. Frosch has authored 299 papers receiving a total of 32.3k indexed citations (citations by other indexed papers that have themselves been cited), including 142 papers in Physiology, 109 papers in Neurology and 81 papers in Molecular Biology. Recurrent topics in Matthew P. Frosch's work include Alzheimer's disease research and treatments (132 papers), Intracerebral and Subarachnoid Hemorrhage Research (48 papers) and Dementia and Cognitive Impairment Research (39 papers). Matthew P. Frosch is often cited by papers focused on Alzheimer's disease research and treatments (132 papers), Intracerebral and Subarachnoid Hemorrhage Research (48 papers) and Dementia and Cognitive Impairment Research (39 papers). Matthew P. Frosch collaborates with scholars based in United States, United Kingdom and Netherlands. Matthew P. Frosch's co-authors include Bradley T. Hyman, Alberto Serrano‐Pozo, Eliezer Masliah, B. T. Hyman, Steven M. Greenberg, Dennis J. Selkoe, Brian J. Bacskai, Rebecca A. Betensky, John H. Growdon and Thomas J. Montine and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Matthew P. Frosch

293 papers receiving 31.8k citations

Hit Papers

Neuropathological Alterations in Alzheimer Disease 2001 2026 2009 2017 2011 2012 2011 2003 2015 500 1000 1.5k 2.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Neuropathological Alterations in Alzheimer Disease
    2011 2.5k citations Matthew P. Frosch et al. profile →
  2. National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease
    2012 2.1k citations Bradley T. Hyman, Thomas G. Beach et al. profile →
  3. National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach
    2011 1.9k citations Thomas G. Beach, Matthew P. Frosch et al. profile →
  4. Insulin-degrading enzyme regulates the levels of insulin, amyloid β-protein, and the β-amyloid precursor protein intracellular domain in vivo
    2003 1.2k citations Wesley Farris, Yang Chang et al. Proceedings of the National Academy of Sciences profile →
  5. A computational atlas of the hippocampal formation using ex vivo, ultra-high resolution MRI: Application to adaptive segmentation of in vivo MRI
    2015 886 citations Jean C. Augustinack, Matthew P. Frosch et al. profile →
  6. Ubiquitination of a New Form of α-Synuclein by Parkin from Human Brain: Implications for Parkinson's Disease
    2001 842 citations Matthew P. Frosch, Kenneth S. Kosik et al. Science profile →
  7. Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer disease
    2006 590 citations Steven M. Greenberg, Brian J. Bacskai et al. profile →
  8. Enhanced Proteolysis of β-Amyloid in APP Transgenic Mice Prevents Plaque Formation, Secondary Pathology, and Premature Death
    2003 585 citations Wesley Farris, Dominic M. Walsh et al. profile →
  9. Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: Recommendations from the Alzheimer’s Association Research Roundtable Workgroup
    2011 554 citations Matthew P. Frosch, Steven M. Greenberg et al. profile →
  10. Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS
    2010 544 citations Matthew P. Frosch, Robert H. Brown et al. profile →
  11. Early Aβ accumulation and progressive synaptic loss, gliosis, and tangle formation in AD brain
    2004 531 citations E. Tessa Hedley‐Whyte, Matthew P. Frosch et al. profile →
  12. Validating novel tau positron emission tomography tracer [F‐18]‐AV‐1451 (T807) on postmortem brain tissue
    2015 450 citations Marta Marquié, Isabel Costantino et al. profile →
  13. A vicious cycle of β amyloid–dependent neuronal hyperactivation
    2019 433 citations Benedikt Zott, Manuel Simon et al. Science profile →
  14. Emerging concepts in sporadic cerebral amyloid angiopathy
    2017 341 citations Andreas Charidimou, Brian J. Bacskai et al. profile →
  15. High-resolution magnetic resonance imaging reveals nuclei of the human amygdala: manual segmentation to automatic atlas
    2017 307 citations Ann C. McKee, Matthew P. Frosch et al. profile →
  16. Vasomotion as a Driving Force for Paravascular Clearance in the Awake Mouse Brain
    2019 291 citations Susanne J. van Veluw, Matthew P. Frosch et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Matthew P. Frosch United States 86 16.8k 9.4k 8.3k 6.5k 6.4k 299 32.3k
Thomas G. Beach United States 89 15.9k 0.9× 9.0k 1.0× 10.6k 1.3× 6.6k 1.0× 5.3k 0.8× 403 31.9k
Thomas J. Montine United States 86 10.8k 0.6× 8.7k 0.9× 6.7k 0.8× 5.2k 0.8× 3.7k 0.6× 439 27.1k
Takeshi Iwatsubo Japan 99 23.2k 1.4× 14.9k 1.6× 12.2k 1.5× 6.1k 0.9× 10.3k 1.6× 463 41.9k
Karen Duff United States 89 18.0k 1.1× 10.9k 1.2× 4.5k 0.5× 5.2k 0.8× 9.6k 1.5× 236 29.5k
Kelly Del Tredici Germany 68 11.3k 0.7× 6.2k 0.7× 20.5k 2.5× 6.6k 1.0× 8.3k 1.3× 145 33.3k
Alison Goate United States 91 15.0k 0.9× 12.2k 1.3× 3.2k 0.4× 4.8k 0.7× 5.4k 0.8× 431 30.4k
Charles Duyckaerts France 72 9.5k 0.6× 6.6k 0.7× 6.6k 0.8× 4.6k 0.7× 5.5k 0.9× 287 21.6k
William R. Markesbery United States 114 22.1k 1.3× 17.0k 1.8× 5.1k 0.6× 6.8k 1.0× 5.8k 0.9× 404 49.9k
Berislav V. Zloković United States 98 17.2k 1.0× 13.0k 1.4× 7.5k 0.9× 18.5k 2.8× 6.8k 1.1× 307 48.0k
Costantino Iadecola United States 111 12.4k 0.7× 12.0k 1.3× 8.6k 1.0× 18.5k 2.8× 7.5k 1.2× 420 52.3k

Countries citing papers authored by Matthew P. Frosch

Since Specialization
Citations

This map shows the geographic impact of Matthew P. Frosch's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Matthew P. Frosch with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Matthew P. Frosch more than expected).

Fields of papers citing papers by Matthew P. Frosch

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Matthew P. Frosch. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Matthew P. Frosch. The network helps show where Matthew P. Frosch may publish in the future.

Co-authorship network of co-authors of Matthew P. Frosch

This figure shows the co-authorship network connecting the top 25 collaborators of Matthew P. Frosch. A scholar is included among the top collaborators of Matthew P. Frosch based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Matthew P. Frosch. Matthew P. Frosch is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Cahill, Daniel P., et al.. (2025). Collision tumor, a metastatic melanoma within a meningioma: a case report. Acta Neuropathologica Communications. 13(1). 57–57.
2.
Sepúlveda‐Falla, Diego, Charles L. White, Geidy E. Serrano, et al.. (2024). Comorbidities in early-onset sporadic versus presenilin-1 mutation-associated Alzheimer disease dementia: Evidence for dependency on Alzheimer disease neuropathological changes. Journal of Neuropathology & Experimental Neurology. 84(2). 104–113. 1 indexed citations
3.
Oltmer, Jan, Emily Williams, Stefan Groha, et al.. (2024). Neuron collinearity differentiates human hippocampal subregions: a validated deep learning approach. Brain Communications. 6(5). fcae296–fcae296. 1 indexed citations
4.
Mehta, Neel H., Emre Kiziltug, Phan Q. Duy, et al.. (2024). Utility of cortical tissue analysis in normal pressure hydrocephalus. Cerebral Cortex. 34(2). 6 indexed citations
5.
Stephen, Christopher D., Sharan R. Srinivasan, Abby L. Olsen, et al.. (2024). Gerstmann‐Sträussler‐Scheinker Disease Presenting as Late‐Onset Slowly Progressive Spinocerebellar Ataxia, and Comparative Case Series with Neuropathology. Movement Disorders Clinical Practice. 11(4). 411–423. 4 indexed citations
6.
Wang, Zemin, Ming Jin, Wei Hong, et al.. (2023). Learnings about Aβ from human brain recommend the use of a live-neuron bioassay for the discovery of next generation Alzheimer’s disease immunotherapeutics. Acta Neuropathologica Communications. 11(1). 39–39. 8 indexed citations
7.
Scherlek, Ashley A., Mariel G. Kozberg, James A. R. Nicoll, et al.. (2022). Histopathological correlates of haemorrhagic lesions on ex vivo magnetic resonance imaging in immunized Alzheimer’s disease cases. Brain Communications. 4(1). fcac021–fcac021. 11 indexed citations
8.
Kamath, Tarun, Naomi Klickstein, Caitlin Commins, et al.. (2021). Kinetics of tau aggregation reveals patient-specific tau characteristics among Alzheimer’s cases. Brain Communications. 3(2). fcab096–fcab096. 6 indexed citations
9.
Rodriguez, Steven, Benjamin R. Schrank, Isabel Costantino, et al.. (2021). Genome-encoded cytoplasmic double-stranded RNAs, found in C9ORF72 ALS-FTD brain, propagate neuronal loss. Science Translational Medicine. 13(601). 29 indexed citations
10.
Veluw, Susanne J. van, Matthew P. Frosch, Ashley A. Scherlek, et al.. (2020). In vivo characterization of spontaneous microhemorrhage formation in mice with cerebral amyloid angiopathy. Journal of Cerebral Blood Flow & Metabolism. 41(1). 82–91. 20 indexed citations
11.
Zott, Benedikt, Manuel Simon, Wei Hong, et al.. (2019). A vicious cycle of β amyloid–dependent neuronal hyperactivation. Science. 365(6453). 559–565. 433 indexed citations breakdown →
12.
Marquié, Marta, Cinthya Agüero, Ana C. Amaral, et al.. (2019). [18F]-AV-1451 binding profile in chronic traumatic encephalopathy: a postmortem case series. Acta Neuropathologica Communications. 7(1). 164–164. 28 indexed citations
13.
Charidimou, Andreas, Matthew P. Frosch, Rustam Al‐Shahi Salman, et al.. (2019). Advancing diagnostic criteria for sporadic cerebral amyloid angiopathy: Study protocol for a multicenter MRI-pathology validation of Boston criteria v2.0. International Journal of Stroke. 14(9). 956–971. 34 indexed citations
14.
DeVos, Sarah L., Bianca T. Corjuc, Derek H. Oakley, et al.. (2018). Synaptic Tau Seeding Precedes Tau Pathology in Human Alzheimer's Disease Brain. Frontiers in Neuroscience. 12. 267–267. 200 indexed citations
15.
Dujardin, Simon, Séverine Bégard, Raphaëlle Caillierez, et al.. (2018). Different tau species lead to heterogeneous tau pathology propagation and misfolding. Acta Neuropathologica Communications. 6(1). 132–132. 80 indexed citations
16.
Garofalo, Kevin, Anke Penno, Brian P. Schmidt, et al.. (2011). Oral l-serine supplementation reduces production of neurotoxic deoxysphingolipids in mice and humans with hereditary sensory autonomic neuropathy type 1. Journal of Clinical Investigation. 121(12). 4735–4745. 152 indexed citations
17.
Tomaso, Emmanuelle di, Matija Snuderl, Walid S. Kamoun, et al.. (2011). Glioblastoma Recurrence after Cediranib Therapy in Patients: Lack of “Rebound” Revascularization as Mode of Escape. Cancer Research. 71(1). 19–28. 156 indexed citations
18.
Nelson, Peter T., Walter A. Kukull, & Matthew P. Frosch. (2010). Thinking Outside the Box: Alzheimer-Type Neuropathology That Does Not Map Directly Onto Current Consensus Recommendations. Journal of Neuropathology & Experimental Neurology. 69(5). 449–454. 27 indexed citations
19.
Farris, Wesley, Yang Chang, Loren Lindsley, et al.. (2003). Insulin-degrading enzyme regulates the levels of insulin, amyloid β-protein, and the β-amyloid precursor protein intracellular domain in vivo. Proceedings of the National Academy of Sciences. 100(7). 4162–4167. 1191 indexed citations breakdown →
20.
Thaler, David E. & Matthew P. Frosch. (2002). Case 16-2002. New England Journal of Medicine. 346(21). 1651–1658. 2 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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