J. Fraser Wright

17.4k citations

89 papers · 7.9k indexed · 2 hit papers · h-index 40

Co-authors: Bernd Hauck Bruce L. Levine Michael C. Milone Michael Kalos David M. Barrett Stephan A. Grupp David T. Teachey Anne Chew
Topics: Virus-based gene therapy research (58 papers)Viral Infectious Diseases and Gene Expression in Insects (35 papers)CAR-T cell therapy research (24 papers)
Cited by: Genetics Oncology Immunology
Journals: New England Journal of Medicine Proceedings of the National Academy of Sciences Nature Communications
Partner nations: United States United Kingdom Canada

In The Last Decade

J. Fraser Wright

87 papers receiving 7.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Chimeric Antigen Receptor–Modified T Cells for Acute Lymphoid Leukemia

2013 2.6k citations Stephan A. Grupp, Michael Kalos et al. New England Journal of Medicine profile →
Efficacy, Safety, and Durability of Voretigene Neparvovec-rzyl in RPE65 Mutation–Associated Inherited Retinal Dystrophy

2019 276 citations J. Fraser Wright, Katherine A. High et al. profile →

Peers

Countries citing papers authored by J. Fraser Wright

Since Specialization

Citations

This map shows the geographic impact of J. Fraser Wright's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by J. Fraser Wright with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites J. Fraser Wright more than expected).

Fields of papers citing papers by J. Fraser Wright

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by J. Fraser Wright. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by J. Fraser Wright. The network helps show where J. Fraser Wright may publish in the future.

Co-authorship network of co-authors of J. Fraser Wright

This figure shows the co-authorship network connecting the top 25 collaborators of J. Fraser Wright. A scholar is included among the top collaborators of J. Fraser Wright based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with J. Fraser Wright. J. Fraser Wright is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	The promising potential of gene therapy for diabetes mellitus 2024 ·Nature Reviews Endocrinology ·Stefan R. Bornstein,J. Fraser Wright,Charlotte Steenblock	5
2	Re-administration of AAV vectors by masking with host albumin: A Goldilocks hypothesis 2023 ·Molecular Therapy ·J. Fraser Wright	3
3	Challenges Posed by Immune Responses to AAV Vectors: Addressing Root Causes 2021 ·Frontiers in Immunology ·(unknown),J. Fraser Wright	78
4	Viral vector manufacturing: quality attributes of rAAV used in clinical development 2020 ·Journal of Biomolecular Techniques JBT ·(unknown),J. Fraser Wright	2
5	Adeno-associated virus vectored immunoprophylaxis to prevent HIV in healthy adults: a phase 1 randomised controlled trial 2019 ·The Lancet HIV ·Frances Priddy,David Lewis,Hans Gelderblom,Hana Hassanin,(unknown),Celia C. LaBranche,Jonathan Hare,Josephine H. Cox,Len Dally,(unknown),David C. Montefiori,Eddy Sayeed,Jim Ackland,Jill Gilmour,Bruce C. Schnepp,J. Fraser Wright,Philip R. Johnson	105
6	Retinal AAV8-RS1 Gene Therapy for X-Linked Retinoschisis: Initial Findings from a Phase I/IIa Trial by Intravitreal Delivery 2018 ·Molecular Therapy ·Catherine A. Cukras,Henry E. Wiley,Brett G. Jeffrey,H. Nida Sen,Amy Turriff,Yong Zeng,Camasamudram Vijayasarathy,Dario Marangoni,Lucia Ziccardi,Sten Kjellström,(unknown),Suja Hiriyanna,J. Fraser Wright,Peter Colosi,Zhijian Wu,Ronald A. Bush,Lisa L. Wei,Paul A. Sieving	178
7	Effects of FVIII immunity on hepatocyte and hematopoietic stem cell–directed gene therapy of murine hemophilia A 2016 ·Molecular Therapy — Methods & Clinical Development ·(unknown),Harrison C. Brown,(unknown),(unknown),J. Fraser Wright,H. Trent Spencer,Christopher B. Doering	23
8	Safety, Biodistribution, and Efficacy of an AAV-5 Vector Encoding Human Interferon-Beta (ART-I02) Delivered via Intra-Articular Injection in Rhesus Monkeys with Collagen-Induced Arthritis 2015 ·PubMed ·Lisette Bevaart,(unknown),Michel Vierboom,(unknown),Ivanela Kondova,(unknown),Bernd Hauck,J. Fraser Wright,Paul P. Tak,Margriet J. Vervoordeldonk	16
9	Safety and tolerability of MRI-guided infusion of AAV2-hAADC into the mid-brain of nonhuman primate 2014 ·Molecular Therapy — Methods & Clinical Development ·Waldy San Sebastián,Adrian P. Kells,John R. Bringas,Lluı́s Samaranch,Piotr Hadaczek,Agnieszka Ciesielska,(unknown),Phillip Pivirotto,John Forsayeth,(unknown),J. Fraser Wright,(unknown),Gregory Heller,Krystof S. Bankiewicz	27
10	Advancing Translational Research Through the NHLBI Gene Therapy Resource Program (GTRP) 2013 ·PubMed ·Cheryl L. McDonald,Janet M. Benson,Kenneth Cornetta,(unknown),Julie Johnston,(unknown),Gensheng Wang,James M. Wilson,J. Fraser Wright,Sonia I. Skarlatos	4
11	Chimeric Antigen Receptor–Modified T Cells for Acute Lymphoid Leukemiabreakdown → 2013 ·New England Journal of Medicine ·Stephan A. Grupp,Michael Kalos,David M. Barrett,Richard Aplenc,David L. Porter,Susan R. Rheingold,David T. Teachey,Anne Chew,Bernd Hauck,J. Fraser Wright,Michael C. Milone,Bruce L. Levine,Carl H. June	2631
12	Assessing the potential for AAV vector genotoxicity in a murine model 2010 ·Blood ·Hojun Li,Nirav Malani,(unknown),Alexander Schlachterman,(unknown),(unknown),Rachel Shah,Valder R. Arruda,Federico Mingozzi,J. Fraser Wright,Frederic D. Bushman,Katherine A. High	190
13	Safety of AAV Factor IX Peripheral Transvenular Gene Delivery to Muscle in Hemophilia B Dogs 2010 ·Molecular Therapy ·Virginia Haurigot,Federico Mingozzi,George Buchlis,Daniel J. Hui,Yifeng Chen,Etiena Basner‐Tschakarjan,Valder R. Arruda,Antoneta Radu,(unknown),J. Fraser Wright,Shangzhen Zhou,Hansell H. Stedman,Dwight A. Bellinger,Timothy C. Nichols,Katherine A. High	52
14	Transient Transfection Methods for Clinical Adeno-Associated Viral Vector Production 2009 ·Human Gene Therapy ·J. Fraser Wright	104
15	High AAV vector purity results in serotype- and tissue-independent enhancement of transduction efficiency 2009 ·Gene Therapy ·Eduard Ayuso,Federico Mingozzi,Joel Montané,Xavier León,Xavier M. Anguela,Virginia Haurigot,Shyrie Edmonson,(unknown),(unknown),Katherine A. High,Fátima Bosch,J. Fraser Wright	217
16	Manufacturing and characterizing AAV-based vectors for use in clinical studies 2008 ·Gene Therapy ·J. Fraser Wright	149
17	Identification of factors that contribute to recombinant AAV2 particle aggregation and methods to prevent its occurrence during vector purification and formulation 2005 ·Molecular Therapy ·J. Fraser Wright,(unknown),(unknown),(unknown),Peter H. Smith,Zhen Zhu,Jürg M. Sommer,Glenn F. Pierce,Guang Qu	118
18	Characterization of platelet‐reactive antibodies in children with varicella‐associated acute immune thrombocytopenic purpura (ITP) 1996 ·British Journal of Haematology ·J. Fraser Wright,Victor S. Blanchette,Hong Wang,Naveen Arya,Martin Petric,John W. Semple,(unknown),John Freedman	72
19	Analysis of platelets by flow cytometry 1995 ·Transfusion Science ·Alan H. Lazarus,J. Fraser Wright,(unknown),John Freedman	11
20	Testing of Monoclonal Antibody Specificity 1983 ·Hybridoma ·J. Fraser Wright,(unknown),Alan G. Scott,K. James	2

About J. Fraser Wright

J. Fraser Wright is a scholar working on Genetics, Molecular Biology and Oncology, having authored 89 papers that have together received 7.9k indexed citations. Recurring topics across this work include Virus-based gene therapy research (58 papers), Viral Infectious Diseases and Gene Expression in Insects (35 papers) and CAR-T cell therapy research (24 papers). The work is most often cited by research in Genetics (3.8k citations), Oncology (3.3k citations) and Immunology (1.4k citations). J. Fraser Wright has collaborated with scholars based in United States, United Kingdom and Canada. Frequent co-authors include Bernd Hauck, Bruce L. Levine, Michael C. Milone, Michael Kalos, David M. Barrett, Stephan A. Grupp, David T. Teachey, Anne Chew, David L. Porter and Richard Aplenc. Their work appears in journals such as New England Journal of Medicine, Proceedings of the National Academy of Sciences and Nature Communications.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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