Roberto Calcedo

10.7k citations

85 papers · 7.9k indexed · 3 hit papers · h-index 45

Impact in

Genetics top 0.1%
- Virus-based gene therapy research
Molecular Biology top 1%
- RNA Interference and Gene Delivery
- CRISPR and Genetic Engineering
- Viral Infectious Diseases and Gene Expression in Insects
- Retinal Development and Disorders

Papers in

Genetics 68
- Virus-based gene therapy research 68
Infectious Diseases 24
- Viral gastroenteritis research and epidemiology 17

Co-authors: James M. Wilson Guangping Gao Lili Wang Luk H. Vandenberghe Mauricio R. Alvira Julie Johnston Jianping Lin You Lü
Journals: Human Gene Therapy (15 papers)Molecular Therapy (11 papers)Journal of Virology (5 papers)Proceedings of the National Academy of Sciences (4 papers)Blood (4 papers)
Partner nations: United States China Spain

In The Last Decade

Roberto Calcedo

83 papers receiving 7.7k citations

Hit Papers

align trajectories log scale

Worldwide Epidemiology of Neutralizing Antibodies to Adeno‐Associated Viruses 2009 · 630 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2009 The Journal of Infectious Diseases
2004 Journal of Virology
2002 Proceedings of the National Academy of Sciences

Peers

Countries citing papers authored by Roberto Calcedo

Since Specialization

Citations

This map shows the geographic impact of Roberto Calcedo's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Roberto Calcedo with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Roberto Calcedo more than expected).

Fields of papers citing papers by Roberto Calcedo

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Roberto Calcedo. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Roberto Calcedo. The network helps show where Roberto Calcedo may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Roberto Calcedo, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Roberto Calcedo Line = papers co-authored together Roberto Calcedo links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	MicroRNA-mediated inhibition of transgene expression reduces dorsal root ganglion toxicity by AAV vectors in primates Science Translational Medicine ·Juliette Hordeaux, Elizabeth L. Buza, Anne-Catherine Moquet, Chunjuan Song, A. Foreau, Yuan Yuan, Yanqing Zhu, Peter Bell, Mingyao Li, Jessica A. Chichester, Roberto Calcedo, James M. Wilson	2020	107
2	Isolating Human Monoclonal Antibodies Against Adeno-Associated Virus From Donors With Pre-existing Immunity Frontiers in Immunology ·April R. Giles, Roberto Calcedo, Anna P. Tretiakova, James M. Wilson	2020	6
3	Toxicology Study of Intra-Cisterna Magna Adeno-Associated Virus 9 Expressing Human Alpha-L-Iduronidase in Rhesus Macaques Molecular Therapy — Methods & Clinical Development ·Juliette Hordeaux, Christian Hinderer, Tamara Goode, Nathan Katz, Elizabeth L. Buza, Peter Bell, Roberto Calcedo, Laura K. Richman, James M. Wilson	2018	76
4	Safety and Efficacy of AAV5 Vectors Expressing Human or Canine CNGB3 in CNGB3 -Mutant Dogs PubMed ·Chereen Haura Puti Aji, András M. Komáromy, Caroline J. Zeiss, Roberto Calcedo, Christine D. Harman, Marx Gr, Enrico Medda, Simone Iwabe, Vince A. Chiodo, William W. Hauswirth, Gustavo D. Aguirre, Jeffrey D. Chulay	2017	24
5	Non-Clinical Study Examining AAV8.TBG.hLDLR Vector-Associated Toxicity in Chow-Fed Wild-Type and LDLR ^+/− Rhesus Macaques Europe PMC (PubMed Central) ·Jenny A. Greig, Maria P. Limberis, Peter Bell, Shu‐Jen Chen, Roberto Calcedo, Daniel J. Rader, James M. Wilson	2017	44
6	5 Year Expression and Neutrophil Defect Repair after Gene Therapy in Alpha-1 Antitrypsin Deficiency Molecular Therapy ·Christian Mueller, Gwladys Gernoux, Alisha M. Gruntman, Florie Borel, Emer P. Reeves, Roberto Calcedo, Farshid N. Rouhani, Anthony T. Yachnis, Margaret Humphries, Martha Campbell‐Thompson, Louis M. Messina, Jeffrey D. Chulay, Bruce C. Trapnell, James M. Wilson, Noel G. McElvaney, Terence R. Flotte	2017	82
7	Immune Responses in 101HEMB01, a Phase 1/2 Open-Label, Single Ascending Dose-Finding Trial of DTX101 (AAVrh10FIX) in Patients with Severe Hemophilia B Blood ·Roberto Calcedo, Leticia Kuri-Cervantes, Hui Peng, Qiuyue Qin, Bhaskar K. Krishna, Mark Schneider, Matt Hewitt, Michael R. Betts, James M. Wilson	2017	9
8	AAV natural infection induces broad cross-neutralizing antibody responses to multiple AAV serotypes in chimpanzees Roberto Calcedo, Mario Heisler	2016	1
9	Safety and Biodistribution Evaluation in Cynomolgus Macaques of rAAV2tYF-PR1.7-hCNGB3, a Recombinant AAV Vector for Treatment of Achromatopsia Guo-jie Ye, Ewa Budzynski, L. Bodsworth, T. Michael Nork, P. Elliott Miller, Giovanni Diodati, James N. Ver Hoeve, Leia M. Smith, Noni F. Pitay, Roberto Calcedo, ALLAN VINICIUS ALMEIDA DO AMARAL, Paulette M. Robinson, David R. Knop, William W. Hauswirth, Jeffrey D. Chulay	2016	1
10	Safety and Biodistribution Evaluation in CNGB3-Deficient Mice of rAAV2tYF-PR1.7-hCNGB3, a Recombinant AAV Vector for Treatment of Achromatopsia PubMed ·Guo-jie Ye, Ewa Budzynski, L. Bodsworth, T. Michael Nork, Paul E. Miller, Zerger Benoît, James N. Ver Hoeve, Leia M. Smith, Aisa Dordari, Shuang Wang, Paulette M. Robinson, Roberto Calcedo, David R. Knop, William W. Hauswirth, Jeffrey D. Chulay	2016	20
11	Safety and Biodistribution Evaluation in Cynomolgus Macaques of rAAV2tYF-PR1.7-hCNGB3, a Recombinant AAV Vector for Treatment of Achromatopsia Europe PMC (PubMed Central) ·Guo-jie Ye, Ewa Budzynski, L. Bodsworth, T. Michael Nork, Paul E. Miller, Alok Sharma, James N. Ver Hoeve, Leia M. Smith, Aisa Dordari, Roberto Calcedo, ALLAN VINICIUS ALMEIDA DO AMARAL, Paulette M. Robinson, David R. Knop, William W. Hauswirth, Jeffrey D. Chulay	2016	53
12	Results at 2 Years after Gene Therapy for RPE65-Deficient Leber Congenital Amaurosis and Severe Early-Childhood–Onset Retinal Dystrophy Ophthalmology ·Richard G. Weleber, Mark E. Pennesi, David J. Wilson, Shalesh Kaushal, Laura Erker, Shuyuan Deng, Irina EnacheAnne-Laure, Terence R. Flotte, Margaret Humphries, Roberto Calcedo, William W. Hauswirth, Jeffrey D. Chulay, J. Timothy Stout	2016	160
13	Evaluation of AAV-mediated Gene Therapy for Central Nervous System Disease in Canine Mucopolysaccharidosis VII Molecular Therapy ·Brittney L. Gurda, E. Harsha, Peter Bell, Yanqing Zhu, Hongwei Yu, Ping Wang, Jessica Bagel, Charles H. Vite, Tracey Sikora, Christian Hinderer, Roberto Calcedo, Franziska Souchon, Richard Steet, Therese Ruane, Patricia O’Donnell, Guangping Gao, James M. Wilson, Margret L. Casal, Katherine P. Ponder, Mark E. Haskins	2015	69
14	Gene Therapy for Mucopolysaccharidosis Type VI Is Effective in Cats Without Pre-Existing Immunity to AAV8 Human Gene Therapy ·Rita Ferla, Thomas O’Malley, Roberto Calcedo, Patricia O’Donnell, Ping Wang, Gabriella Cotugno, S. Ouali, James M. Wilson, Mark E. Haskins, Alberto Auricchio	2012	38
15	Phase 2 Clinical Trial of a Recombinant Adeno-Associated Viral Vector Expressing α ₁ -Antitrypsin: Interim Results Human Gene Therapy ·Terence R. Flotte, Bruce C. Trapnell, Margaret Humphries, Brenna Carey, Roberto Calcedo, Farshid N. Rouhani, Martha Campbell‐Thompson, Anthony T. Yachnis, Robert A. Sandhaus, Noel G. McElvaney, Christian Mueller, Louis M. Messina, James M. Wilson, Mark Brantly, David R. Knop, Guo-jie Ye, Jeffrey D. Chulay	2011	265
16	Systematic Evaluation of AAV Vectors for Liver directed Gene Transfer in Murine Models Molecular Therapy ·Lili Wang, Huan Wang, Peter Bell, Robert McCarter, 由理恵齋藤, Roberto Calcedo, Luk H. Vandenberghe, Hiroki Morizono, Mark L. Batshaw, James M. Wilson	2009	107
17	Use of chimeric adenoviral vectors to assess capsid neutralization determinants Virology ·Soumitra Roy, Yanik Eka Triana, Roberto Calcedo, Corinna Lebherz, Julio Sanmiguel, Di Wu, James M. Wilson	2005	33
18	Biology of AAV Serotype Vectors in Liver-Directed Gene Transfer to Nonhuman Primates Molecular Therapy ·Guangping Gao, You Lü, Roberto Calcedo, Rebecca Grant, Peter Bell, Lili Wang, Joanita Figueredo, Martin Lock, James M. Wilson	2005	140
19	Erythropoietin gene therapy leads to autoimmune anemia in macaques Blood ·Guangping Gao, Corinna Lebherz, Daniel J. Weiner, Rebecca Grant, Roberto Calcedo, Beth McCullough, Adam Bagg, Yi Zhang, James M. Wilson	2003	113
20	Noninvasive gene transfer to the lung for systemic delivery of therapeutic proteins Journal of Clinical Investigation ·Alberto Auricchio, Erin O’Connor, Daniel E. Weiner, Guangping Gao, Markus Hildinger, Lili Wang, Roberto Calcedo, James M. Wilson	2002	20

About Roberto Calcedo

Roberto Calcedo is a scholar working on Genetics, Infectious Diseases, Virology, Animal Science and Zoology and Epidemiology, having authored 85 papers that have together received 7.9k indexed citations. Recurring topics across this work include Virus-based gene therapy research (68 papers), Viral gastroenteritis research and epidemiology (17 papers), RNA Interference and Gene Delivery (16 papers), Herpesvirus Infections and Treatments (16 papers), Viral Infectious Diseases and Gene Expression in Insects (15 papers), CAR-T cell therapy research (12 papers), Viral Infections and Immunology Research (11 papers) and Animal Virus Infections Studies (8 papers). The work is most often cited by research in Genetics (5.9k citations), Molecular Biology (5.2k citations), Infectious Diseases (1.2k citations), Oncology (1.5k citations) and Cardiology and Cardiovascular Medicine (1.1k citations). Roberto Calcedo has collaborated with scholars based in United States, China and Spain. Frequent co-authors include James M. Wilson, Guangping Gao, Lili Wang, Luk H. Vandenberghe, Mauricio R. Alvira, Julie Johnston, Jianping Lin, You Lü, Peter Bell and Xiangyang Zhou. Their work appears in journals such as Human Gene Therapy, Molecular Therapy, Journal of Virology, Proceedings of the National Academy of Sciences and Blood.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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