Xavier León

1.2k total citations
16 papers, 547 citations indexed

About

Xavier León is a scholar working on Molecular Biology, Physiology and Epidemiology. According to data from OpenAlex, Xavier León has authored 16 papers receiving a total of 547 indexed citations (citations by other indexed papers that have themselves been cited), including 11 papers in Molecular Biology, 6 papers in Physiology and 4 papers in Epidemiology. Recurrent topics in Xavier León's work include Protein Structure and Dynamics (6 papers), Lysosomal Storage Disorders Research (4 papers) and Lipid Membrane Structure and Behavior (3 papers). Xavier León is often cited by papers focused on Protein Structure and Dynamics (6 papers), Lysosomal Storage Disorders Research (4 papers) and Lipid Membrane Structure and Behavior (3 papers). Xavier León collaborates with scholars based in Spain, France and United States. Xavier León's co-authors include Fátima Bosch, Virginia Haurigot, Esteve Padrós, Federico Mingozzi, Gérard Leblanc, Shyrie Edmonson, Katherine A. High, Eduard Ayuso, J. Fraser Wright and Xavier M. Anguela and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Nature Communications.

In The Last Decade

Xavier León

16 papers receiving 542 citations

Peers

Xavier León
Michael K. Parente United States
J Jaeken Belgium
R. Vervoort Belgium
A. Olson United States
Salvatore Cortellino United States
Michael K. Parente United States
Xavier León
Citations per year, relative to Xavier León Xavier León (= 1×) peers Michael K. Parente

Countries citing papers authored by Xavier León

Since Specialization
Citations

This map shows the geographic impact of Xavier León's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Xavier León with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Xavier León more than expected).

Fields of papers citing papers by Xavier León

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Xavier León. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Xavier León. The network helps show where Xavier León may publish in the future.

Co-authorship network of co-authors of Xavier León

This figure shows the co-authorship network connecting the top 25 collaborators of Xavier León. A scholar is included among the top collaborators of Xavier León based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Xavier León. Xavier León is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

16 of 16 papers shown
1.
Jiménez, Verónica, Victor Sacristan, Miquel García, et al.. (2024). 898-P: AAV-FGF21 Gene Therapy Extends Healthspan in Old Mice. Diabetes. 73(Supplement_1). 1 indexed citations
2.
Casana, Estefanía, Verónica Jiménez, Claudia Jambrina, et al.. (2022). AAV-mediated BMP7 gene therapy counteracts insulin resistance and obesity. Molecular Therapy — Methods & Clinical Development. 25. 190–204. 19 indexed citations
3.
Mayo‐Yáñez, Miguel, Christian Calvo‐Henríquez, Tareck Ayad, et al.. (2021). COVID-19 Pandemic and its Impact on the Management of Head and Neck Cancer in the Spanish Healthcare System.. International Archives of Otorhinolaryngology. 25(4). e610–e615. 1 indexed citations
4.
Marcó, Sara, Virginia Haurigot, Albert Ribera, et al.. (2021). Seven-year follow-up of durability and safety of AAV CNS gene therapy for a lysosomal storage disorder in a large animal. Molecular Therapy — Methods & Clinical Development. 23. 370–389. 24 indexed citations
5.
Ribera, Albert, Miquel García, Anna Pujol, et al.. (2021). Treatment of skeletal and non-skeletal alterations of Mucopolysaccharidosis type IVA by AAV-mediated gene therapy. Nature Communications. 12(1). 5343–5343. 23 indexed citations
6.
Casana, Estefanía, Verónica Jiménez, Victor Sacristan, et al.. (2020). BMP7 overexpression in adipose tissue induces white adipogenesis and improves insulin sensitivity in ob/ob mice. International Journal of Obesity. 45(2). 449–460. 16 indexed citations
7.
Roca, Carles, Sandra Motas, Sara Marcó, et al.. (2017). Disease correction by AAV-mediated gene therapy in a new mouse model of mucopolysaccharidosis type IIID. Human Molecular Genetics. 26(8). 1535–1551. 43 indexed citations
8.
Motas, Sandra, Virginia Haurigot, Miquel García, et al.. (2016). CNS-directed gene therapy for the treatment of neurologic and somatic mucopolysaccharidosis type II (Hunter syndrome). JCI Insight. 1(9). e86696–e86696. 56 indexed citations
9.
Ribera, Albert, Virginia Haurigot, Miquel García, et al.. (2014). Biochemical, histological and functional correction of mucopolysaccharidosis Type IIIB by intra-cerebrospinal fluid gene therapy. Human Molecular Genetics. 24(7). 2078–2095. 46 indexed citations
10.
Lorenz, V., Xavier León, & Esteve Padrós. (2012). Studying Substrate Binding to Reconstituted Secondary Transporters by Attenuated Total Reflection Infrared Difference Spectroscopy. Methods in molecular biology. 914. 107–126. 9 indexed citations
11.
Granell, Meritxell, Xavier León, Gérard Leblanc, Esteve Padrós, & V. Lorenz. (2010). Structural insights into the activation mechanism of melibiose permease by sodium binding. Proceedings of the National Academy of Sciences. 107(51). 22078–22083. 33 indexed citations
12.
Ayuso, Eduard, Federico Mingozzi, Joel Montané, et al.. (2009). High AAV vector purity results in serotype- and tissue-independent enhancement of transduction efficiency. Gene Therapy. 17(4). 503–510. 217 indexed citations
13.
León, Xavier, Gérard Leblanc, & Esteve Padrós. (2009). Alteration of Sugar-Induced Conformational Changes of the Melibiose Permease by Mutating Arg141 in Loop 4-5. Biophysical Journal. 96(12). 4877–4886. 9 indexed citations
14.
Lorenz, V., Meritxell Granell, Xavier León, Gérard Leblanc, & Esteve Padrós. (2009). In-Plane and Out-of-Plane Infrared Difference Spectroscopy Unravels Tilting of Helices and Structural Changes in a Membrane Protein upon Substrate Binding. Journal of the American Chemical Society. 131(42). 15094–15095. 17 indexed citations
15.
León, Xavier, et al.. (2006). Changes in Secondary Structures and Acidic Side Chains of Melibiose Permease upon Cosubstrates Binding. Biophysical Journal. 91(12). 4440–4449. 13 indexed citations
16.
León, Xavier, et al.. (2005). Substrate-Induced Conformational Changes of Melibiose Permease from Escherichia coli Studied by Infrared Difference Spectroscopy. Biochemistry. 44(9). 3506–3514. 20 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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