Irene Scarfò

3.7k total citations · 3 hit papers
32 papers, 2.2k citations indexed

About

Irene Scarfò is a scholar working on Oncology, Molecular Biology and Immunology. According to data from OpenAlex, Irene Scarfò has authored 32 papers receiving a total of 2.2k indexed citations (citations by other indexed papers that have themselves been cited), including 28 papers in Oncology, 10 papers in Molecular Biology and 10 papers in Immunology. Recurrent topics in Irene Scarfò's work include CAR-T cell therapy research (27 papers), CRISPR and Genetic Engineering (7 papers) and Immune Cell Function and Interaction (5 papers). Irene Scarfò is often cited by papers focused on CAR-T cell therapy research (27 papers), CRISPR and Genetic Engineering (7 papers) and Immune Cell Function and Interaction (5 papers). Irene Scarfò collaborates with scholars based in United States, Denmark and Italy. Irene Scarfò's co-authors include Marcela V. Maus, Amanda A. Bouffard, Andrea Schmidts, Rebecca C. Larson, Matthew J. Frigault, Ana P. Castaño, Mark B. Leick, Stefanie R. Bailey, Bryan D. Choi and Bob S. Carter and has published in prestigious journals such as Nature, Nature Communications and Journal of Clinical Oncology.

In The Last Decade

Irene Scarfò

31 papers receiving 2.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Engineered CRISPR–Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing

2019 453 citations Benjamin P. Kleinstiver, Alexander A. Sousa et al. Nature Biotechnology profile →
CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicity

2019 426 citations Bryan D. Choi, Xiaoling Yu et al. Nature Biotechnology profile →
CAR T cell killing requires the IFNγR pathway in solid but not liquid tumours

2022 225 citations Rebecca C. Larson, Michael C. Kann et al. Nature profile →

Peers

Irene Scarfò

ONCOL

IMMUN

GENET

Elena Sotillo United States

Amanda A. Bouffard United States

Paula L. Kosasih United States

Mark B. Leick United States

Haiying Qin United States

Valentina Hoyos United States

Andrea Schmidts United States

Giedre Krenciute United States

Sarwish Rafiq United States

Dayenne G. van Leeuwen United States

Elena Sotillo United States

Irene Scarfò

1.6k ×1.1

ONCOL

980 ×0.9

491 ×0.9

588 ×1.1

IMMUN

396 ×0.8

GENET

Citations per year, relative to Irene Scarfò Irene Scarfò (= 1×) peers Elena Sotillo

Countries citing papers authored by Irene Scarfò

Since Specialization

Citations

This map shows the geographic impact of Irene Scarfò's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Irene Scarfò with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Irene Scarfò more than expected).

Fields of papers citing papers by Irene Scarfò

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Irene Scarfò. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Irene Scarfò. The network helps show where Irene Scarfò may publish in the future.

Co-authorship network of co-authors of Irene Scarfò

This figure shows the co-authorship network connecting the top 25 collaborators of Irene Scarfò. A scholar is included among the top collaborators of Irene Scarfò based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Irene Scarfò. Irene Scarfò is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Korell, Felix, Irene Scarfò, Harrison Silva, et al.. (2025). Combining MCL-1 inhibition and CD37-directed chimeric antigen receptor T cells as an effective strategy to target T-cell lymphoma. Leukemia. 39(10). 2452–2464. 1 indexed citations

Landon, Mark B., Irene Scarfò, Michelle Nguyen, et al.. (2024). Development of AB-2100, an autologous integrated circuit T (ICT) cell therapy targeting CA9 intended for the treatment of ccRCC.. Journal of Clinical Oncology. 42(4_suppl). 472–472. 1 indexed citations

Williams, Jasper Z., Dina Polyak, James Zhang, et al.. (2023). 323 Preclinical development of AB-1015, an integrated circuit T cell therapy containing an ALPG/MSLN logic gate and FAS/PTPN2 shRNA-miR, for the treatment of ovarian cancer. SHILAP Revista de lepidopterología. A367–A367. 1 indexed citations

Larson, Rebecca C., Michael C. Kann, Charlotte Graham, et al.. (2023). Anti-TACI single and dual-targeting CAR T cells overcome BCMA antigen loss in multiple myeloma. Nature Communications. 14(1). 7509–7509. 23 indexed citations

Larson, Rebecca C., Michael C. Kann, Stefanie R. Bailey, et al.. (2022). CAR T cell killing requires the IFNγR pathway in solid but not liquid tumours. Nature. 604(7906). 563–570. 225 indexed citations breakdown →

Leick, Mark B., Harrison Silva, Irene Scarfò, et al.. (2022). Non-cleavable hinge enhances avidity and expansion of CAR-T cells for acute myeloid leukemia. Cancer Cell. 40(5). 494–508.e5. 88 indexed citations

Jan, Max, Irene Scarfò, Rebecca C. Larson, et al.. (2021). Reversible ON- and OFF-switch chimeric antigen receptors controlled by lenalidomide. Science Translational Medicine. 13(575). 180 indexed citations

Scarfò, Irene, Kathleen Gallagher, Mark B. Leick, et al.. (2021). Effects of Prior Exposure to Tec Kinase(BTK/ITK) Inhibitors on Kte-X19 Products. Blood. 138(Supplement 1). 3849–3849. 3 indexed citations

Schmidts, Andrea, Amanda A. Bouffard, Angela C. Boroughs, et al.. (2020). Cell-based artificial APC resistant to lentiviral transduction for efficient generation of CAR-T cells from various cell sources. Journal for ImmunoTherapy of Cancer. 8(2). e000990–e000990. 18 indexed citations

10.

Kleinstiver, Benjamin P., Alexander A. Sousa, Russell T. Walton, et al.. (2020). Publisher Correction: Engineered CRISPR–Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing. Nature Biotechnology. 38(7). 901–901. 6 indexed citations

11.

Schmidts, Andrea, Maria Ormhøj, Bryan D. Choi, et al.. (2019). Rational design of a trimeric APRIL-based CAR-binding domain enables efficient targeting of multiple myeloma. Blood Advances. 3(21). 3248–3260. 85 indexed citations

12.

Choi, Bryan D., Xiaoling Yu, Ana P. Castaño, et al.. (2019). CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicity. Nature Biotechnology. 37(9). 1049–1058. 426 indexed citations breakdown →

13.

Kleinstiver, Benjamin P., Alexander A. Sousa, Russell T. Walton, et al.. (2019). Engineered CRISPR–Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing. Nature Biotechnology. 37(3). 276–282. 453 indexed citations breakdown →

14.

Choi, Bryan D., Xiaoling Yu, Ana P. Castaño, et al.. (2019). CRISPR-Cas9 disruption of PD-1 enhances activity of universal EGFRvIII CAR T cells in a preclinical model of human glioblastoma. Journal for ImmunoTherapy of Cancer. 7(1). 304–304. 228 indexed citations

15.

Scarfò, Irene, Matthew J. Frigault, & Marcela V. Maus. (2019). CAR-Based Approaches to Cutaneous T-Cell Lymphoma. Frontiers in Oncology. 9. 259–259. 19 indexed citations

16.

Wang, Xiao, Irene Scarfò, Andrea Schmidts, et al.. (2019). Dynamic Profiling of Antitumor Activity of CAR T Cells Using Micropatterned Tumor Arrays. Advanced Science. 6(23). 1901829–1901829. 23 indexed citations

17.

Scarfò, Irene, Maria Ormhøj, Matthew J. Frigault, et al.. (2018). Anti-CD37 chimeric antigen receptor T cells are active against B- and T-cell lymphomas. Blood. 132(14). 1495–1506. 105 indexed citations

18.

Schmidts, Andrea, Maria Ormhøj, Allison Taylor, et al.. (2018). Engineering an Optimized Trimeric APRIL-Based CAR to Broaden Targetability of Multiple Myeloma. Blood. 132(Supplement 1). 2059–2059. 6 indexed citations

19.

Scarfò, Irene & Marcela V. Maus. (2017). Current approaches to increase CAR T cell potency in solid tumors: targeting the tumor microenvironment. Journal for ImmunoTherapy of Cancer. 5(1). 28–28. 153 indexed citations

20.

Scarfò, Irene, Elisa Pellegrino, Elisabetta Mereu, Giorgio Inghirami, & Roberto Piva. (2016). Transposable elements: The enemies within. Experimental Hematology. 44(10). 913–916. 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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