Ira Tabas

65.2k total citations · 25 hit papers
278 papers, 46.3k citations indexed

About

Ira Tabas is a scholar working on Immunology, Molecular Biology and Surgery. According to data from OpenAlex, Ira Tabas has authored 278 papers receiving a total of 46.3k indexed citations (citations by other indexed papers that have themselves been cited), including 131 papers in Immunology, 109 papers in Molecular Biology and 96 papers in Surgery. Recurrent topics in Ira Tabas's work include Phagocytosis and Immune Regulation (72 papers), Cholesterol and Lipid Metabolism (64 papers) and Atherosclerosis and Cardiovascular Diseases (53 papers). Ira Tabas is often cited by papers focused on Phagocytosis and Immune Regulation (72 papers), Cholesterol and Lipid Metabolism (64 papers) and Atherosclerosis and Cardiovascular Diseases (53 papers). Ira Tabas collaborates with scholars based in United States, Germany and Canada. Ira Tabas's co-authors include Kevin Jon Williams, David Ron, Kathryn J. Moore, Frederick R. Maxfield, Karin Bornfeldt, Stuart Kornfeld, Alan R. Tall, Arif Yurdagul, Tracie A. Seimon and George Kuriakose and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Ira Tabas

273 papers receiving 45.5k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

2011 2.2k citations Ira Tabas et al. profile →
Macrophages in the Pathogenesis of Atherosclerosis

2011 2.1k citations Ira Tabas et al. profile →
The Response-to-Retention Hypothesis of Early Atherogenesis

1995 1.1k citations Ira Tabas et al. profile →
Role of cholesterol and lipid organization in disease

2005 1.1k citations Ira Tabas et al. profile →
Inflammation and its resolution in atherosclerosis: mediators and therapeutic opportunities

2019 1.1k citations Arif Yurdagul, Ira Tabas et al. profile →
Subendothelial Lipoprotein Retention as the Initiating Process in Atherosclerosis

2007 1.0k citations Ira Tabas et al. Circulation profile →
Anti-Inflammatory Therapy in Chronic Disease: Challenges and Opportunities

2013 862 citations Ira Tabas et al. profile →
Macrophage death and defective inflammation resolution in atherosclerosis

2009 861 citations Ira Tabas profile →
Macrophage Phenotype and Function in Different Stages of Atherosclerosis

2016 838 citations Ira Tabas et al. Circulation Research profile →
Recent insights into the cellular biology of atherosclerosis

2015 774 citations Ira Tabas et al. profile →
The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages

2003 735 citations George Kuriakose, Ira Tabas et al. profile →
Insulin Resistance, Hyperglycemia, and Atherosclerosis

2011 678 citations Ira Tabas et al. profile →
Efferocytosis in health and disease

2019 649 citations Amanda C. Doran, Arif Yurdagul et al. profile →
Inflammation and plaque vulnerability

2015 599 citations Peter Libby, Ira Tabas et al. profile →
Autophagy Regulates Cholesterol Efflux from Macrophage Foam Cells via Lysosomal Acid Lipase

2011 590 citations Ira Tabas et al. profile →
Consequences and Therapeutic Implications of Macrophage Apoptosis in Atherosclerosis

2005 518 citations Ira Tabas profile →
Macrophage Autophagy Plays a Protective Role in Advanced Atherosclerosis

2012 513 citations Ira Tabas et al. profile →
Role of ERO1-α–mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress–induced apoptosis

2009 503 citations Gang Li, Ira Tabas et al. profile →
Monocyte-Macrophages and T Cells in Atherosclerosis

2017 460 citations Ira Tabas et al. profile →
Mechanisms of Fibrosis Development in Nonalcoholic Steatohepatitis

2020 446 citations Robert F. Schwabe, Ira Tabas et al. profile →
Macrophage-targeted nanomedicine for the diagnosis and treatment of atherosclerosis

2021 370 citations Jinjun Shi, Ira Tabas et al. profile →
An imbalance between specialized pro-resolving lipid mediators and pro-inflammatory leukotrienes promotes instability of atherosclerotic plaques

2016 326 citations George Kuriakose, Ira Tabas et al. Nature Communications profile →
Macrophage Metabolism of Apoptotic Cell-Derived Arginine Promotes Continual Efferocytosis and Resolution of Injury

2020 321 citations Arif Yurdagul, Xiaobo Wang et al. profile →
Hepatocyte TAZ/WWTR1 Promotes Inflammation and Fibrosis in Nonalcoholic Steatohepatitis

2016 313 citations Xiaobo Wang, Ze Zheng et al. profile →
Efferocytosis induces macrophage proliferation to help resolve tissue injury

2021 209 citations Brennan D. Gerlach, Patrick B. Ampomah et al. profile →

Peers

Countries citing papers authored by Ira Tabas

Since Specialization

Citations

This map shows the geographic impact of Ira Tabas's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ira Tabas with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ira Tabas more than expected).

Fields of papers citing papers by Ira Tabas

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ira Tabas. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ira Tabas. The network helps show where Ira Tabas may publish in the future.

Co-authorship network of co-authors of Ira Tabas

This figure shows the co-authorship network connecting the top 25 collaborators of Ira Tabas. A scholar is included among the top collaborators of Ira Tabas based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ira Tabas. Ira Tabas is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Macrophage WDFY3 mitigates autoimmunity by enhancing efferocytosis and suppressing T cell activation in mice 2025 ·Nature Communications ·Xun Wu, Ziyi Wang, Katherine R. Croce, Fang Li, Jian Cui, Vivette D. D’Agati, Rajesh K. Soni, Ira Tabas, Ai Yamamoto, Hanrui Zhang	0
2	A non-apoptotic caspase-8–meteorin pathway in hepatocytes promotes MASH fibrosis 2025 ·Nature Metabolism ·Xiaobo Wang, (unknown), Hongxue Shi, Yang Xiao, (unknown), (unknown), Zhiping Hu, Shareef Khalid, Danish Saleheen, Dwayne G. Stupack, Tatiana Kisseleva, (unknown), Mitchell A. Lazar, Ira Tabas	0
3	Impaired TIM4-mediated efferocytosis by liver macrophages contributes to fibrosis in metabolic dysfunction–associated steatohepatitis 2025 ·Science Translational Medicine ·Hongxue Shi, Xiaobo Wang, (unknown), Brennan D. Gerlach, Arif Yurdagul, (unknown), (unknown), Faridoddin Mirshahi, Luisa Ronzoni, (unknown), Luca Valenti, Chyuan‐Sheng Lin, James D. Montgomery, Bradley A. Zinker, Michael Klichinsky, Ira Tabas	2
4	Efferocytosis drives a tryptophan metabolism pathway in macrophages to promote tissue resolution 2024 ·Nature Metabolism ·(unknown), Patrick B. Ampomah, Lancia Darville, (unknown), Xiaobo Wang, George Kuriakose, Yuling Xiao, Jinjun Shi, John M. Koomen, Robert H. McCusker, Ira Tabas	31
5	Efferocytosis in liver disease 2023 ·JHEP Reports ·Hongxue Shi, (unknown), Xiaobo Wang, Ira Tabas	18
6	Blockade of IL-6 signaling alleviates atherosclerosis in Tet2-deficient clonal hematopoiesis 2023 ·Nature Cardiovascular Research ·Wenli Liu, Mustafa Yalçınkaya, (unknown), Malgorzata Olszewska, Patrick B. Ampomah, J. Brett Heimlich, Ranran Wang, (unknown), Tong Xiao, Alexander G. Bick, Ross L. Levine, Eirini P. Papapetrou, Peter Libby, Ira Tabas, Nan Wang, Alan R. Tall	38
7	BRCC3-Mediated NLRP3 Deubiquitylation Promotes Inflammasome Activation and Atherosclerosis in Tet2 Clonal Hematopoiesis 2023 ·Circulation ·Mustafa Yalçınkaya, Wenli Liu, (unknown), Malgorzata Olszewska, Tong Xiao, Sandra Abramowicz, Eirini P. Papapetrou, Marit Westerterp, Nan Wang, Ira Tabas, Alan R. Tall	42
8	Macrophages use apoptotic cell-derived methionine and DNMT3A during efferocytosis to promote tissue resolution 2022 ·Nature Metabolism ·Patrick B. Ampomah, Bishuang Cai, (unknown), Brennan D. Gerlach, Arif Yurdagul, Xiaobo Wang, George Kuriakose, Lancia Darville, Yan Sun, Simone Sidoli, John M. Koomen, Alan R. Tall, Ira Tabas	98
9	A genome-wide CRISPR screen identifies WDFY3 as a regulator of macrophage efferocytosis 2022 ·Nature Communications ·Jianting Shi, Xun Wu, Ziyi Wang, Fang Li, Yujiao Meng, (unknown), Jian Cui, Chenyi Xue, Katherine R. Croce, Arif Yurdagul, John G. Doench, Wei Li, Konstantinos Zarbalis, Ira Tabas, Ai Yamamoto, Hanrui Zhang	26
10	CD47-SIRPα axis blockade in NASH promotes necroptotic hepatocyte clearance by liver macrophages and decreases hepatic fibrosis 2022 ·Science Translational Medicine ·Hongxue Shi, Xiaobo Wang, Fang Li, Brennan D. Gerlach, Arif Yurdagul, (unknown), (unknown), Hanrui Zhang, Bishuang Cai, Ze Zheng, Luca Valenti, Ira Tabas	55
11	Hepatocyte TLR4 triggers inter-hepatocyte Jagged1/Notch signaling to determine NASH-induced fibrosis 2021 ·Science Translational Medicine ·Junjie Yu, Changyu Zhu, Xiaobo Wang, KyeongJin Kim, Alberto Bartolomé, Paola Dongiovanni, Katherine P. Yates, Luca Valenti, Michele Carrer, Thorsten Sadowski, Li Qiang, Ira Tabas, Joel E. Lavine, Utpal B. Pajvani	94
12	Interacting hepatic PAI-1/tPA gene regulatory pathways influence impaired fibrinolysis severity in obesity 2020 ·Journal of Clinical Investigation ·Ze Zheng, Keiko Nakamura, (unknown), Xiaobo Wang, Sherry Thomas, Marc Bessler, Beth Schrope, (unknown), Rui-Ming Liu, Lale Özcan, José A. López, Ira Tabas	28
13	siRNA nanoparticles targeting CaMKIIγ in lesional macrophages improve atherosclerotic plaque stability in mice 2020 ·Science Translational Medicine ·Wei Tao, Arif Yurdagul, Na Kong, (unknown), Xiaobo Wang, Amanda C. Doran, Chan Feng, Junqing Wang, Mohammad Ariful Islam, Omid C. Farokhzad, Ira Tabas, Jinjun Shi	191
14	The neutrophil–lymphocyte ratio and incident atherosclerotic events: analyses from five contemporary randomized trials 2020 ·European Heart Journal ·Nicholas Adamstein, Jean MacFadyen, Lynda Rose, Robert J. Glynn, Amit K. Dey, Peter Libby, Ira Tabas, Nehal N. Mehta, Paul M. Ridker	222
15	An ATF6-tPA pathway in hepatocytes contributes to systemic fibrinolysis and is repressed by DACH1 2018 ·Blood ·Ze Zheng, Lalitha Nayak, (unknown), Arif Yurdagul, Xiaobo Wang, Bishuang Cai, Stephanie Lapping, Lale Özcan, Rajasekhar Ramakrishnan, Richard G. Pestell, Mukesh K. Jain, Ira Tabas	19
16	Hepatocyte Notch activation induces liver fibrosis in nonalcoholic steatohepatitis 2018 ·Science Translational Medicine ·Changyu Zhu, KyeongJin Kim, Xiaobo Wang, Alberto Bartolomé, Marcela Salomao, Paola Dongiovanni, Marica Meroni, Mark J. Graham, Katherine P. Yates, Anna Mae Diehl, Robert F. Schwabe, Ira Tabas, Luca Valenti, Joel E. Lavine, Utpal B. Pajvani	194
17	Macrophage Mitochondrial Oxidative Stress Promotes Atherosclerosis and Nuclear Factor-κB–Mediated Inflammation in Macrophages 2013 ·Circulation Research ·Ying Wang, (unknown), Peter S. Rabinovitch, Ira Tabas	215
18	Impaired MEK Signaling and SERCA Expression Promote ER Stress and Apoptosis in Insulin-Resistant Macrophages and Are Reversed by Exenatide Treatment 2012 ·Diabetes ·Chien-Ping Liang, Seongah Han, Gang Li, Ira Tabas, Alan R. Tall	52
19	Cholesterol in health and disease 2002 ·Journal of Clinical Investigation ·Ira Tabas	147
20	Cholesterol in health and disease 2002 ·Journal of Clinical Investigation ·Ira Tabas	3

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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