Mark J. Graham

18.6k total citations · 9 hit papers
154 papers, 13.7k citations indexed

About

Mark J. Graham is a scholar working on Molecular Biology, Surgery and Epidemiology. According to data from OpenAlex, Mark J. Graham has authored 154 papers receiving a total of 13.7k indexed citations (citations by other indexed papers that have themselves been cited), including 53 papers in Molecular Biology, 45 papers in Surgery and 29 papers in Epidemiology. Recurrent topics in Mark J. Graham's work include Liver Disease Diagnosis and Treatment (20 papers), Lipoproteins and Cardiovascular Health (17 papers) and Lipid metabolism and biosynthesis (17 papers). Mark J. Graham is often cited by papers focused on Liver Disease Diagnosis and Treatment (20 papers), Lipoproteins and Cardiovascular Health (17 papers) and Lipid metabolism and biosynthesis (17 papers). Mark J. Graham collaborates with scholars based in United States, United Kingdom and Japan. Mark J. Graham's co-authors include Rosanne M. Crooke, Richard Lee, Brenda F. Baker, Richard S. Geary, Joseph L. Witztum, Steven G. Hughes, Brett P. Monia, Sotirios Tsimikas, Stanley T. Crooke and W. S. Singleton and has published in prestigious journals such as New England Journal of Medicine, Proceedings of the National Academy of Sciences and The Lancet.

In The Last Decade

Mark J. Graham

153 papers receiving 13.5k citations

Hit Papers

miR-122 regulation of lipid metabolism revealed by in viv... 2006 2026 2012 2019 2006 2013 2016 2014 2017 500 1000 1.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting
    2006 1.7k citations Sheri Booten, Mark J. Graham et al. Cell Metabolism profile →
  2. Trimethylamine-N-Oxide, a Metabolite Associated with Atherosclerosis, Exhibits Complex Genetic and Dietary Regulation
    2013 812 citations Richard Lee, Mark J. Graham et al. Cell Metabolism profile →
  3. Antisense oligonucleotides targeting apolipoprotein(a) in people with raised lipoprotein(a): two randomised, double-blind, placebo-controlled, dose-ranging trials
    2016 544 citations Nicholas J. Viney, Richard S. Geary et al. The Lancet profile →
  4. Targeted delivery of antisense oligonucleotides to hepatocytes using triantennaryN-acetyl galactosamine improves potency 10-fold in mice
    2014 468 citations Mark J. Graham, Sheri Booten et al. profile →
  5. Cardiovascular and Metabolic Effects of ANGPTL3 Antisense Oligonucleotides
    2017 454 citations Mark J. Graham, Richard Lee et al. New England Journal of Medicine profile →
  6. Antisense Inhibition of Apolipoprotein C-III in Patients with Hypertriglyceridemia
    2015 409 citations Brenda F. Baker, W. S. Singleton et al. New England Journal of Medicine profile →
  7. Targeting APOC3 in the Familial Chylomicronemia Syndrome
    2014 381 citations W. S. Singleton, Steven G. Hughes et al. New England Journal of Medicine profile →
  8. Antisense therapy targeting apolipoprotein(a): a randomised, double-blind, placebo-controlled phase 1 study
    2015 358 citations Sotirios Tsimikas, Nicholas J. Viney et al. The Lancet profile →
  9. Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction
    2019 296 citations Sifan Chen, Michael C. Petriello et al. Cell Metabolism profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Mark J. Graham United States 57 6.4k 3.7k 2.9k 2.6k 2.4k 154 13.7k
Matti Jauhiainen Finland 60 3.9k 0.6× 4.9k 1.3× 2.0k 0.7× 4.1k 1.6× 2.2k 0.9× 371 13.6k
Jorge Plutzky United States 65 7.9k 1.2× 4.0k 1.1× 1.7k 0.6× 4.4k 1.7× 3.6k 1.5× 186 18.1k
Srinivasa T. Reddy United States 67 4.5k 0.7× 4.4k 1.2× 2.5k 0.9× 3.3k 1.3× 1.5k 0.6× 245 15.7k
Rama Natarajan United States 79 10.0k 1.6× 2.3k 0.6× 4.2k 1.5× 2.8k 1.1× 1.6k 0.7× 246 18.5k
Kerry‐Anne Rye Australia 65 4.7k 0.7× 6.2k 1.7× 2.4k 0.8× 5.1k 2.0× 2.0k 0.9× 266 13.4k
Shun Ishibashi Japan 67 6.6k 1.0× 6.4k 1.7× 2.3k 0.8× 4.1k 1.6× 2.5k 1.0× 360 17.2k
Willa A. Hsueh United States 72 7.1k 1.1× 3.3k 0.9× 1.8k 0.6× 3.8k 1.5× 4.9k 2.1× 251 18.1k
MacRae F. Linton United States 65 5.5k 0.9× 5.5k 1.5× 2.1k 0.7× 2.4k 0.9× 2.3k 1.0× 231 15.8k
Muredach P. Reilly United States 70 4.9k 0.8× 4.0k 1.1× 1.6k 0.6× 2.5k 1.0× 4.2k 1.8× 302 18.5k
Ruth McPherson Canada 52 3.8k 0.6× 3.8k 1.0× 1.5k 0.5× 2.1k 0.8× 1.8k 0.8× 197 11.4k

Countries citing papers authored by Mark J. Graham

Since Specialization
Citations

This map shows the geographic impact of Mark J. Graham's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mark J. Graham with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mark J. Graham more than expected).

Fields of papers citing papers by Mark J. Graham

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mark J. Graham. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mark J. Graham. The network helps show where Mark J. Graham may publish in the future.

Co-authorship network of co-authors of Mark J. Graham

This figure shows the co-authorship network connecting the top 25 collaborators of Mark J. Graham. A scholar is included among the top collaborators of Mark J. Graham based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Mark J. Graham. Mark J. Graham is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Attie, Alan, Mark P. Keller, Kelly A. Mitok, et al.. (2021). Reversal of hypertriglyceridemia in diabetic BTBR ob/ob mice does not prevent nephropathy. Laboratory Investigation. 101(7). 935–941. 12 indexed citations
2.
Kanter, Jenny E., Baohai Shao, Farah Kramer, et al.. (2019). Increased apolipoprotein C3 drives cardiovascular risk in type 1 diabetes. Journal of Clinical Investigation. 129(10). 4165–4179. 77 indexed citations
3.
Chen, Sifan, Michael C. Petriello, Kymberleigh A. Romano, et al.. (2019). Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction. Cell Metabolism. 30(6). 1141–1151.e5. 296 indexed citations breakdown →
4.
Zhu, Changyu, KyeongJin Kim, Xiaobo Wang, et al.. (2018). Hepatocyte Notch activation induces liver fibrosis in nonalcoholic steatohepatitis. Science Translational Medicine. 10(468). 194 indexed citations
5.
Margolis, Carmi Z., et al.. (2017). Student Reflection Papers on a Global Clinical Experience: A Qualitative Study. Annals of Global Health. 83(2). 333–333. 9 indexed citations
6.
Graham, Mark J., Richard Lee, Teresa Brandt, et al.. (2017). Cardiovascular and Metabolic Effects of ANGPTL3 Antisense Oligonucleotides. New England Journal of Medicine. 377(3). 222–232. 454 indexed citations breakdown →
7.
Sun, Xiaowei, Mary E. Haas, Ji Miao, et al.. (2015). Insulin Dissociates the Effects of Liver X Receptor on Lipogenesis, Endoplasmic Reticulum Stress, and Inflammation. Journal of Biological Chemistry. 291(3). 1115–1122. 16 indexed citations
8.
Miao, Ji, Praveen V. Manthena, Mary Gearing, et al.. (2015). Flavin-containing monooxygenase 3 as a potential player in diabetes-associated atherosclerosis. Nature Communications. 6(1). 6498–6498. 298 indexed citations
9.
Tsimikas, Sotirios, Nicholas J. Viney, Steven G. Hughes, et al.. (2015). Antisense therapy targeting apolipoprotein(a): a randomised, double-blind, placebo-controlled phase 1 study. The Lancet. 386(10002). 1472–1483. 358 indexed citations breakdown →
10.
Pedrelli, Matteo, Padideh Davoodpour, Chiara Degirolamo, et al.. (2014). Hepatic ACAT2 Knock Down Increases ABCA1 and Modifies HDL Metabolism in Mice. PLoS ONE. 9(4). e93552–e93552. 24 indexed citations
11.
12.
Haas, Joel T., Ji Miao, Dipanjan Chanda, et al.. (2012). Hepatic Insulin Signaling Is Required for Obesity-Dependent Expression of SREBP-1c mRNA but Not for Feeding-Dependent Expression. Cell Metabolism. 15(6). 873–884. 155 indexed citations
13.
Lee, Richard, Wuxia Fu, Mark J. Graham, et al.. (2012). Comparison of the pharmacological profiles of murine antisense oligonucleotides targeting apolipoprotein B and microsomal triglyceride transfer protein. Journal of Lipid Research. 54(3). 602–614. 31 indexed citations
14.
Brown, J. Mark, Jenna L. Betters, Caleb C. Lord, et al.. (2010). CGI-58 knockdown in mice causes hepatic steatosis but prevents diet-induced obesity and glucose intolerance. Journal of Lipid Research. 51(11). 3306–3315. 125 indexed citations
15.
Sayre, N., Victoria Rimkunas, Mark J. Graham, Rosanne M. Crooke, & Laura Liscum. (2010). Recovery from liver disease in a Niemann-Pick type C mouse model. Journal of Lipid Research. 51(8). 2372–2383. 19 indexed citations
16.
Stahl, Simone H., Mark Davies, David I. Cook, & Mark J. Graham. (2008). Nuclear hormone receptor-dependent regulation of hepatic transporters and their role in the adaptive response in cholestasis. Xenobiotica. 38(7-8). 725–777. 24 indexed citations
17.
Antwi, Daniel A., Ravindra Dhir, Xiaoyan Yin, et al.. (2008). Inhibition of ADRP prevents diet-induced insulin resistance. American Journal of Physiology-Gastrointestinal and Liver Physiology. 295(3). G621–G628. 95 indexed citations
18.
Vickers, Timothy A., Hong Zhang, Mark J. Graham, et al.. (2006). Modification of MyD88 mRNA Splicing and Inhibition of IL-1β Signaling in Cell Culture and in Mice with a 2′- O -Methoxyethyl-Modified Oligonucleotide. The Journal of Immunology. 176(6). 3652–3661. 40 indexed citations
19.
Graham, Mark J., et al.. (2003). mRNA and protein expression of dog liver cytochromes P450 in relation to the metabolism of human CYP2C substrates. Xenobiotica. 33(3). 225–237. 28 indexed citations
20.
Graham, Mark J.. (2002). A Dream Realized: The Development of King/Drew Magnet High School of Medicine and Science.. 37(3). 16–19.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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