Seppo Ylä‐Herttuala

61.9k total citations · 7 hit papers
748 papers, 44.5k citations indexed

About

Seppo Ylä‐Herttuala is a scholar working on Molecular Biology, Genetics and Surgery. According to data from OpenAlex, Seppo Ylä‐Herttuala has authored 748 papers receiving a total of 44.5k indexed citations (citations by other indexed papers that have themselves been cited), including 444 papers in Molecular Biology, 175 papers in Genetics and 159 papers in Surgery. Recurrent topics in Seppo Ylä‐Herttuala's work include Virus-based gene therapy research (162 papers), Angiogenesis and VEGF in Cancer (154 papers) and Atherosclerosis and Cardiovascular Diseases (93 papers). Seppo Ylä‐Herttuala is often cited by papers focused on Virus-based gene therapy research (162 papers), Angiogenesis and VEGF in Cancer (154 papers) and Atherosclerosis and Cardiovascular Diseases (93 papers). Seppo Ylä‐Herttuala collaborates with scholars based in Finland, United States and United Kingdom. Seppo Ylä‐Herttuala's co-authors include Kari Alitalo, Wulf Palinski, Joseph L. Witztum, Michael E. Rosenfeld, Daniel Steinberg, Tuomas T. Rissanen, Jukka Luoma, T E Carew, Sampath Parthasarathy and Mikko P. Turunen and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and The Lancet.

In The Last Decade

Seppo Ylä‐Herttuala

736 papers receiving 43.4k citations

Hit Papers

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What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man.

1989 1.6k citations Seppo Ylä‐Herttuala et al. Journal of Clinical Investigation profile →
Low density lipoprotein undergoes oxidative modification in vivo.

1989 1.3k citations Seppo Ylä‐Herttuala et al. Proceedings of the National Academy of Sciences profile →
Autoantibody against oxidised LDL and progression of carotid atherosclerosis

1992 1.1k citations H Korpela, Seppo Ylä‐Herttuala et al. profile →
Expression of monocyte chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions.

1991 771 citations Seppo Ylä‐Herttuala et al. Proceedings of the National Academy of Sciences profile →
Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3

2001 612 citations David G. Jackson, Seppo Ylä‐Herttuala et al. profile →
Antisera and monoclonal antibodies specific for epitopes generated during oxidative modification of low density lipoprotein.

1990 533 citations Seppo Ylä‐Herttuala et al. profile →
Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth.

2001 531 citations Seppo Ylä‐Herttuala, Kari Alitalo et al. profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author						Papers	Cites
Seppo Ylä‐Herttuala	21.8k	9.9k	9.0k	8.3k	5.3k	748	44.5k
Michael B. Sporn	44.7k 2.0×	12.8k 1.3×	5.3k 0.6×	8.4k 1.0×	8.0k 1.5×	512	73.5k
Tatsuhiko Kodama	20.1k 0.9×	6.7k 0.7×	4.8k 0.5×	9.3k 1.1×	2.5k 0.5×	426	36.3k
Michael A. Gimbrone	16.2k 0.7×	3.6k 0.4×	6.4k 0.7×	12.9k 1.6×	1.7k 0.3×	185	42.7k
Göran K. Hansson	14.0k 0.6×	4.6k 0.5×	9.5k 1.0×	28.1k 3.4×	1.8k 0.3×	455	53.2k
Kenneth Walsh	28.3k 1.3×	4.3k 0.4×	7.2k 0.8×	6.2k 0.7×	2.9k 0.5×	462	54.0k
Ryozo Nagai	18.1k 0.8×	2.9k 0.3×	7.4k 0.8×	4.7k 0.6×	4.8k 0.9×	859	45.6k
Andreas M. Zeiher	32.0k 1.5×	5.6k 0.6×	17.6k 2.0×	8.2k 1.0×	1.5k 0.3×	564	69.3k
Stefanie Dimmeler	42.9k 2.0×	6.7k 0.7×	15.9k 1.8×	9.3k 1.1×	1.8k 0.3×	518	73.2k
Guy A. Zimmerman	10.5k 0.5×	2.5k 0.3×	3.9k 0.4×	8.6k 1.0×	2.1k 0.4×	262	32.6k
Ira Tabas	20.0k 0.9×	2.6k 0.3×	10.9k 1.2×	15.8k 1.9×	1.3k 0.2×	278	46.3k

Countries citing papers authored by Seppo Ylä‐Herttuala

Since Specialization

Citations

This map shows the geographic impact of Seppo Ylä‐Herttuala's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Seppo Ylä‐Herttuala with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Seppo Ylä‐Herttuala more than expected).

Fields of papers citing papers by Seppo Ylä‐Herttuala

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Seppo Ylä‐Herttuala. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Seppo Ylä‐Herttuala. The network helps show where Seppo Ylä‐Herttuala may publish in the future.

Co-authorship network of co-authors of Seppo Ylä‐Herttuala

This figure shows the co-authorship network connecting the top 25 collaborators of Seppo Ylä‐Herttuala. A scholar is included among the top collaborators of Seppo Ylä‐Herttuala based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Seppo Ylä‐Herttuala. Seppo Ylä‐Herttuala is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Martini, Alberto, Ganiraju C. Manyam, Yan Chen, et al.. (2024). Single-cell RNA sequencing analysis identifies acute changes in the tumor microenvironment induced by interferon α gene therapy in a murine bladder cancer model. Frontiers in Immunology. 15. 1387229–1387229. 2 indexed citations

Jahromi, Behnam Rezai, Miko Valori, Riikka Tulamo, et al.. (2024). Cancer-type somatic mutations in saccular cerebral aneurysms. European Journal of Human Genetics. 33(8). 1076–1079.

Hosseini, Seyed Younes, Rahul Mallick, Petri Mäkinen, & Seppo Ylä‐Herttuala. (2024). Navigating the prime editing strategy to treat cardiovascular genetic disorders in transforming heart health. Expert Review of Cardiovascular Therapy. 22(1-3). 75–89. 1 indexed citations

Ruotsalainen, Anna‐Kaisa, et al.. (2024). The mechanisms of Chr.9p21.3 risk locus in coronary artery disease: where are we today?. American Journal of Physiology-Heart and Circulatory Physiology. 328(2). H196–H208. 1 indexed citations

Kaljunen, Heidi, Lucia Nappi, Ladan Fazli, et al.. (2024). DPYSL5 is highly expressed in treatment-induced neuroendocrine prostate cancer and promotes lineage plasticity via EZH2/PRC2. Communications Biology. 7(1). 108–108. 8 indexed citations

Ruotsalainen, Anna‐Kaisa, Tiit Örd, Janne Heikkilä, et al.. (2023). Deletion of the murine ortholog of human 9p21.3 locus promotes atherosclerosis by increasing macrophage proinflammatory activity. Frontiers in Cardiovascular Medicine. 10. 1113890–1113890. 5 indexed citations

Abdollahzadeh, Ali, H. Y. Huang, Fabrizio Orsenigo, et al.. (2023). SproutAngio: an open-source bioimage informatics tool for quantitative analysis of sprouting angiogenesis and lumen space. Scientific Reports. 13(1). 7279–7279. 5 indexed citations

Kivelä, Antti, et al.. (2022). Intramyocardial adenoviral vascular endothelial growth factor‐D^∆N∆C gene therapy does not induce ventricular arrhythmias. The Journal of Gene Medicine. 24(8). e3437–e3437. 3 indexed citations

Mäkinen, Petri I., Minna U. Kaikkonen, Marc S. Weinberg, et al.. (2022). Nuclear microRNA-466c regulates Vegfa expression in response to hypoxia. PLoS ONE. 17(3). e0265948–e0265948. 12 indexed citations

10.

Ståhle, Mia, Sanna Hellberg, Jenni Virta, et al.. (2021). Evaluation of glucagon-like peptide-1 receptor expression in nondiabetic and diabetic atherosclerotic mice using PET tracer Ga-68-NODAGA-exendin-4. STM:n Hallinnonalan avoin julkaisuarkisto (Julkari). 1 indexed citations

11.

Korpela, H, Rahul Mallick, Pyry I. Toivanen, et al.. (2021). Adenoviral VEGF-B186R127S gene transfer induces angiogenesis and improves perfusion in ischemic heart. iScience. 24(12). 103533–103533. 6 indexed citations

12.

Afara, Isaac O., Mikko J. Nissi, Paavo Halonen, et al.. (2020). Quantification of Myocardial Blood Flow by Machine Learning Analysis of Modified Dual Bolus MRI Examination. Annals of Biomedical Engineering. 49(2). 653–662. 4 indexed citations

13.

Choi, Woonyoung, Sharada Mokkapati, Debasish Sundi, et al.. (2019). Inhibition of urothelial carcinoma through targeted type I interferon-mediated immune activation. OncoImmunology. 8(5). e1577125–e1577125. 10 indexed citations

14.

Sallinen, Hanna, J. Koponen, Maarit Anttila, et al.. (2013). Preclinical Safety, Toxicology, and Biodistribution Study of Adenoviral Gene Therapy with sVEGFR-2 and sVEGFR-3 Combined with Chemotherapy for Ovarian Cancer. PubMed. 24(1). 29–37. 9 indexed citations

15.

Leinonen, Hanna, Anna‐Kaisa Ruotsalainen, Ann‐Marie Määttä, et al.. (2012). Oxidative Stress-Regulated Lentiviral TK/GCV Gene Therapy for Lung Cancer Treatment. Cancer Research. 72(23). 6227–6235. 37 indexed citations

16.

Samaranayake, Haritha, et al.. (2009). Challenges in monoclonal antibody-based therapies. Annals of Medicine. 41(5). 322–331. 137 indexed citations

17.

Rossi, Derrick J., Iiro Rajantie, Seppo Ylä‐Herttuala, et al.. (2008). Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothelium and are not needed for tumor growth. Proceedings of the National Academy of Sciences. 105(18). 6620–6625. 294 indexed citations

18.

Bałuk, Peter, Tuomas Tammela, Natalya Lyubynska, et al.. (2005). Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation. Journal of Clinical Investigation. 115(2). 247–257. 470 indexed citations

19.

Krebs, R., Jussi Tikkanen, Antti I. Nykänen, et al.. (2005). Dual Role of Vascular Endothelial Growth Factor in Experimental Obliterative Bronchiolitis. American Journal of Respiratory and Critical Care Medicine. 171(12). 1421–1429. 37 indexed citations

20.

Pakkanen, Timo, Jukka Luoma, Saila Laakso, et al.. (1996). Local adventitial VEGF gene transfer reduces neointima formation in rabbit carotid arteries. UCL Discovery (University College London). 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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