Hisako Kayama

7.5k total citations · 3 hit papers
64 papers, 4.8k citations indexed

About

Hisako Kayama is a scholar working on Immunology, Molecular Biology and Epidemiology. According to data from OpenAlex, Hisako Kayama has authored 64 papers receiving a total of 4.8k indexed citations (citations by other indexed papers that have themselves been cited), including 39 papers in Immunology, 22 papers in Molecular Biology and 16 papers in Epidemiology. Recurrent topics in Hisako Kayama's work include Immune Cell Function and Interaction (17 papers), Gut microbiota and health (13 papers) and IL-33, ST2, and ILC Pathways (13 papers). Hisako Kayama is often cited by papers focused on Immune Cell Function and Interaction (17 papers), Gut microbiota and health (13 papers) and IL-33, ST2, and ILC Pathways (13 papers). Hisako Kayama collaborates with scholars based in Japan, United Kingdom and United States. Hisako Kayama's co-authors include Kiyoshi Takeda, Ryu Okumura, Masahiro Yamamoto, Shimon Sakaguchi, Makoto Kinoshita, Eiji Umemoto, Megumi Okuyama, Hiroyuki Saiga, Yosuke Shimada and Takashi Kusu and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Hisako Kayama

63 papers receiving 4.8k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Interaction Between the Microbiota, Epithelia, and Immune Cells in the Intestine

2020 513 citations Hisako Kayama, Ryu Okumura et al. profile →
Dysbiosis Contributes to Arthritis Development via Activation of Autoreactive T Cells in the Intestine

2016 482 citations Yuichi Maeda, Takashi Kurakawa et al. profile →
Interleukin-10-Producing Plasmablasts Exert Regulatory Function in Autoimmune Inflammation

2014 419 citations Hisako Kayama, Shimon Sakaguchi et al. Immunity profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Hisako Kayama Japan	33	2.2k	1.7k	909	636	572	64	4.8k
Hao Li China	43	3.2k 1.4×	2.7k 1.6×	529 0.6×	745 1.2×	423 0.7×	228	7.5k
Nicolas Bouladoux United States	35	2.2k 1.0×	4.8k 2.9×	849 0.9×	940 1.5×	563 1.0×	52	8.1k
Janine L. Coombes United Kingdom	18	1.3k 0.6×	4.1k 2.4×	582 0.6×	400 0.6×	787 1.4×	28	5.8k
Mario M. Zaiss Germany	36	2.6k 1.2×	1.3k 0.8×	308 0.3×	444 0.7×	428 0.7×	73	4.9k
Danielle Malo Canada	38	1.8k 0.8×	3.1k 1.9×	1.0k 1.1×	1.2k 1.8×	705 1.2×	114	7.0k
André Gessner Germany	40	1.9k 0.9×	2.9k 1.7×	989 1.1×	981 1.5×	260 0.5×	172	6.7k
Jason A. Hall United States	19	2.3k 1.0×	5.5k 3.3×	675 0.7×	701 1.1×	740 1.3×	26	8.2k
Stefan Hippenstiel Germany	52	2.7k 1.2×	2.6k 1.5×	1.8k 2.0×	839 1.3×	322 0.6×	159	7.4k
Richard I. Tapping United States	35	1.6k 0.7×	2.5k 1.5×	942 1.0×	470 0.7×	289 0.5×	62	4.9k
Hans-Christian Reinecker United States	32	1.5k 0.7×	2.9k 1.7×	610 0.7×	626 1.0×	932 1.6×	43	5.3k

Countries citing papers authored by Hisako Kayama

Since Specialization

Citations

This map shows the geographic impact of Hisako Kayama's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hisako Kayama with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hisako Kayama more than expected).

Fields of papers citing papers by Hisako Kayama

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hisako Kayama. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hisako Kayama. The network helps show where Hisako Kayama may publish in the future.

Co-authorship network of co-authors of Hisako Kayama

This figure shows the co-authorship network connecting the top 25 collaborators of Hisako Kayama. A scholar is included among the top collaborators of Hisako Kayama based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Hisako Kayama. Hisako Kayama is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Ito, Takayoshi, Taiki Sakaguchi, Shuichi Shimma, et al.. (2025). Intestinal Foxl1+ cell-derived CXCL12 maintains epithelial homeostasis by modulating cellular metabolism. International Immunology. 37(4). 235–250. 1 indexed citations

Metwally, Hozaifa, Hisako Kayama, Kazuki Okuyama, et al.. (2025). Threonine phosphorylation of STAT1 safeguards gut epithelial integrity and restricts interferon-mediated cytotoxicity. Proceedings of the National Academy of Sciences. 122(30). e2511957122–e2511957122. 2 indexed citations

Yasumizu, Yoshiaki, Takeshi Harada, Katsumi Fumoto, et al.. (2025). Hypoxia-induced Wnt5a-secreting fibroblasts promote colon cancer progression. Nature Communications. 16(1). 3653–3653.

Ito, Takayoshi, Bo Li, Daisuke Okuzaki, et al.. (2023). The UDP-glucose/P2Y14 receptor axis promotes eosinophil-dependent large intestinal inflammation. International Immunology. 36(4). 155–166. 4 indexed citations

Kamiyama, Naganori, et al.. (2023). TRAF6 signaling in dendritic cells plays protective role against infectious colitis by limiting C. rodentium infection through the induction of Th1 and Th17 responses. Biochemical and Biophysical Research Communications. 669. 103–112. 1 indexed citations

Nii, Takuro, Yuichi Maeda, Daisuke Motooka, et al.. (2023). Genomic repertoires linked with pathogenic potency of arthritogenic Prevotella copri isolated from the gut of patients with rheumatoid arthritis. Annals of the Rheumatic Diseases. 82(5). 621–629. 57 indexed citations

Nakagawa, Natsuki, Yoshiko Hashii, Hisako Kayama, et al.. (2022). An oral WT1 protein vaccine composed of WT1-anchored, genetically engineered Bifidobacterium longum allows for intestinal immunity in mice with acute myeloid leukemia. Cancer Immunology Immunotherapy. 72(1). 39–53. 14 indexed citations

Kayama, Hisako, Toshihiro Kishikawa, Shinichiro Shinzaki, et al.. (2022). Lysophosphatidylserines derived from microbiota in Crohn’s disease elicit pathological Th1 response. The Journal of Experimental Medicine. 219(7). 23 indexed citations

Li, Bo, Takashi Kusu, Ryu Okumura, et al.. (2021). The ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis through modulation of P2X4 receptor–dependent metabolism in myeloid cells. Proceedings of the National Academy of Sciences. 118(39). 16 indexed citations

10.

Ogino, Takayuki, Hisako Kayama, Daisuke Okuzaki, et al.. (2020). Human NKp44+ Group 3 Innate Lymphoid Cells Associate with Tumor-Associated Tertiary Lymphoid Structures in Colorectal Cancer. Cancer Immunology Research. 8(6). 724–731. 40 indexed citations

11.

Pareek, Siddhika, Takashi Kurakawa, Bhabatosh Das, et al.. (2019). Comparison of Japanese and Indian intestinal microbiota shows diet-dependent interaction between bacteria and fungi. npj Biofilms and Microbiomes. 5(1). 37–37. 66 indexed citations

12.

Sekido, Yuki, Yoshiaki Yasumizu, Junichi Nishimura, et al.. (2018). Innate Myeloid Cell Subset-Specific Gene Expression Patterns in the Human Colon are Altered in Crohn’s Disease Patients. Digestion. 99(3). 194–204. 1 indexed citations

13.

Kayama, Hisako, Daisuke Okuzaki, Ritsuko Koga, et al.. (2017). BATF2 inhibits immunopathological Th17 responses by suppressing Il23a expression during Trypanosoma cruzi infection. The Journal of Experimental Medicine. 214(5). 1313–1331. 35 indexed citations

14.

Chinen, Ichino, Taisuke Nakahama, Akihiro Kimura, et al.. (2015). The aryl hydrocarbon receptor/microRNA-212/132 axis in T cells regulates IL-10 production to maintain intestinal homeostasis. International Immunology. 27(8). 405–415. 73 indexed citations

15.

Ishii, Hiroshi, Shihori Tanabe, Masaki Ueno, et al.. (2013). ifn-γ-dependent secretion of IL-10 from Th1 cells and microglia/macrophages contributes to functional recovery after spinal cord injury. Cell Death and Disease. 4(7). e710–e710. 55 indexed citations

16.

Yamamoto, Masahiro, Megumi Okuyama, Taishi Kimura, et al.. (2012). A Cluster of Interferon-γ-Inducible p65 GTPases Plays a Critical Role in Host Defense against Toxoplasma gondii. Immunity. 37(2). 302–313. 250 indexed citations

17.

Okuyama, Megumi, Hisako Kayama, Koji Atarashi, et al.. (2010). A novel in vivo inducible dendritic cell ablation model in mice. Biochemical and Biophysical Research Communications. 397(3). 559–563. 10 indexed citations

18.

Morishita, Hideaki, Fumitake Saito, Hisako Kayama, et al.. (2009). Fra-1 negatively regulates lipopolysaccharide-mediated inflammatory responses. International Immunology. 21(4). 457–465. 16 indexed citations

19.

Yamamoto, Masahiro, Daron M. Standley, Seiji Takashima, et al.. (2009). A single polymorphic amino acid on Toxoplasma gondii kinase ROP16 determines the direct and strain-specific activation of Stat3. The Journal of Experimental Medicine. 206(12). 2747–2760. 183 indexed citations

20.

Nishimura, Jun‐ichi, Hiroyuki Saiga, Shintaro Sato, et al.. (2008). Potent Antimycobacterial Activity of Mouse Secretory Leukocyte Protease Inhibitor. The Journal of Immunology. 180(6). 4032–4039. 32 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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