Lesley E. Smythies

5.8k total citations · 2 hit papers
63 papers, 4.7k citations indexed

About

Lesley E. Smythies is a scholar working on Immunology, Surgery and Molecular Biology. According to data from OpenAlex, Lesley E. Smythies has authored 63 papers receiving a total of 4.7k indexed citations (citations by other indexed papers that have themselves been cited), including 47 papers in Immunology, 18 papers in Surgery and 11 papers in Molecular Biology. Recurrent topics in Lesley E. Smythies's work include Immune Cell Function and Interaction (16 papers), Helicobacter pylori-related gastroenterology studies (15 papers) and Immune cells in cancer (14 papers). Lesley E. Smythies is often cited by papers focused on Immune Cell Function and Interaction (16 papers), Helicobacter pylori-related gastroenterology studies (15 papers) and Immune cells in cancer (14 papers). Lesley E. Smythies collaborates with scholars based in United States, Chile and United Kingdom. Lesley E. Smythies's co-authors include Phillip D. Smith, Ronald H. Clements, Marty T. Sellers, Meg Mosteller‐Barnum, Jan M. Orenstein, Gang Meng, William H. Benjamin, Paul R. Harris, Ruizhong Shen and R. Alan Wilson and has published in prestigious journals such as Journal of Biological Chemistry, Circulation and Journal of Clinical Investigation.

In The Last Decade

Lesley E. Smythies

60 papers receiving 4.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity

2005 660 citations Lesley E. Smythies, Marty T. Sellers et al. Journal of Clinical Investigation profile →
Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity

2005 647 citations Lesley E. Smythies, Marty T. Sellers et al. Journal of Clinical Investigation profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Lesley E. Smythies United States	33	2.6k	1.2k	1.1k	590	508	63	4.7k
Madeline Fort United States	22	2.5k 0.9×	680 0.6×	813 0.7×	991 1.7×	342 0.7×	38	4.1k
Esther C. de Jong Netherlands	49	5.8k 2.2×	606 0.5×	1.8k 1.6×	482 0.8×	700 1.4×	111	8.9k
Alistair J. Ramsay Australia	37	3.4k 1.3×	524 0.4×	992 0.9×	581 1.0×	850 1.7×	81	6.3k
Sean P. Spencer United States	23	2.6k 1.0×	1.1k 0.9×	1.2k 1.1×	229 0.4×	603 1.2×	29	4.6k
Marika C. Kullberg United States	30	3.1k 1.2×	644 0.5×	742 0.7×	838 1.4×	786 1.5×	41	5.5k
Charlotte S. Kaetzel United States	35	1.8k 0.7×	369 0.3×	1.5k 1.3×	662 1.1×	649 1.3×	69	4.7k
Hans-Christian Reinecker United States	32	2.9k 1.1×	647 0.5×	1.5k 1.3×	932 1.6×	626 1.2×	43	5.3k
Janine L. Coombes United Kingdom	18	4.1k 1.5×	406 0.3×	1.3k 1.2×	787 1.3×	400 0.8×	28	5.8k
Kathrin S. Michelsen United States	36	4.0k 1.5×	812 0.7×	1.9k 1.7×	900 1.5×	681 1.3×	64	6.8k
Brian L. Kelsall United States	51	6.6k 2.5×	777 0.6×	1.8k 1.6×	1.5k 2.5×	1.1k 2.3×	107	9.8k

Countries citing papers authored by Lesley E. Smythies

Since Specialization

Citations

This map shows the geographic impact of Lesley E. Smythies's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lesley E. Smythies with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lesley E. Smythies more than expected).

Fields of papers citing papers by Lesley E. Smythies

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lesley E. Smythies. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lesley E. Smythies. The network helps show where Lesley E. Smythies may publish in the future.

Co-authorship network of co-authors of Lesley E. Smythies

This figure shows the co-authorship network connecting the top 25 collaborators of Lesley E. Smythies. A scholar is included among the top collaborators of Lesley E. Smythies based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Lesley E. Smythies. Lesley E. Smythies is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Rocha, Clarissa Santos, Katie L. Alexander, Carolina Herrera, et al.. (2025). Microbial remodeling of gut tryptophan metabolism and indole-3-lactate production regulate epithelial barrier repair and viral suppression in human and simian immunodeficiency virus infections. Mucosal Immunology. 18(3). 583–595. 6 indexed citations

Smythies, Lesley E., Olga V. Belyaeva, Katie L. Alexander, et al.. (2024). Human intestinal stromal cells promote homeostasis in normal mucosa but inflammation in Crohn’s disease in a retinoic acid–deficient manner. Mucosal Immunology. 17(5). 958–972.

Alexander, Katie L., Carolina Serrano, Asmi Chakraborty, et al.. (2020). Modulation of glycosyltransferase ST6Gal-I in gastric cancer-derived organoids disrupts homeostatic epithelial cell turnover. Journal of Biological Chemistry. 295(41). 14153–14163. 29 indexed citations

Smythies, Lesley E., Robert Grabski, Li Mao, et al.. (2018). Cytomegalovirus promotes intestinal macrophage-mediated mucosal inflammation through induction of Smad7. Mucosal Immunology. 11(6). 1694–1704. 29 indexed citations

Robinson, Tanya O., Mingce Zhang, Christina Ochsenbauer, Lesley E. Smythies, & Randy Q. Cron. (2017). CD4 regulatory T cells augment HIV-1 expression of polarized M1 and M2 monocyte derived macrophages. Virology. 504. 79–87. 15 indexed citations

Kumar, Ranjit, Carolina Serrano, Travis Ptacek, et al.. (2017). Helicobacter pylori infection is associated with an altered gastric microbiota in children. Mucosal Immunology. 10(5). 1169–1177. 73 indexed citations

Shen, Ruizhong, Jenna E. Achenbach, Jeremy Rahkola, et al.. (2015). Mother-to-Child HIV-1 Transmission Events Are Differentially Impacted by Breast Milk and Its Components from HIV-1-Infected Women. PLoS ONE. 10(12). e0145150–e0145150. 6 indexed citations

Bimczok, Diane, John Y. Kao, Peter Mannon, et al.. (2014). Human gastric epithelial cells contribute to gastric immune regulation by providing retinoic acid to dendritic cells. Mucosal Immunology. 8(3). 533–544. 44 indexed citations

Smythies, Lesley E. & John Smythies. (2014). Microbiota, the immune system, black moods and the brainâ€”melancholia updated. Frontiers in Human Neuroscience. 8. 720–720. 23 indexed citations

10.

Shen, Ruizhong, Ernesto Drelichman, Diane Bimczok, et al.. (2010). GP41-Specific Antibody Blocks Cell-Free HIV Type 1 Transcytosis through Human Rectal Mucosa and Model Colonic Epithelium. The Journal of Immunology. 184(7). 3648–3655. 50 indexed citations

11.

Xie, Shutao, Jun Li, Qi Wu, et al.. (2010). IL-17 Activates the Canonical NF-κB Signaling Pathway in Autoimmune B Cells of BXD2 Mice To Upregulate the Expression of Regulators of G-Protein Signaling 16. The Journal of Immunology. 184(5). 2289–2296. 89 indexed citations

12.

Harris, Paul R., Shelton W. Wright, Carolina Serrano, et al.. (2008). Helicobacter pylori Gastritis in Children Is Associated With a Regulatory T-Cell Response. Gastroenterology. 134(2). 491–499. 190 indexed citations

13.

León, Francisco, Lesley E. Smythies, Phillip D. Smith, & Brian L. Kelsall. (2006). Involvement of Dendritic Cells in the Pathogenesis of Inflammatory Bowel Disease. Advances in experimental medicine and biology. 579. 117–132. 34 indexed citations

14.

Smythies, Lesley E., Marty T. Sellers, Ronald H. Clements, et al.. (2005). Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity. Journal of Clinical Investigation. 115(1). 66–75. 647 indexed citations breakdown →

15.

Smith, Phillip D., Christina Ochsenbauer‐Jambor, & Lesley E. Smythies. (2005). Intestinal macrophages: unique effector cells of the innate immune system. Immunological Reviews. 206(1). 149–159. 169 indexed citations

16.

Smith, Phillip D., Lesley E. Smythies, Meg Mosteller‐Barnum, et al.. (2001). Intestinal Macrophages Lack CD14 and CD89 and Consequently Are Down-Regulated for LPS- and IgA-Mediated Activities. The Journal of Immunology. 167(5). 2651–2656. 254 indexed citations

17.

Smythies, Lesley E., Ken B. Waites, J. Russell Lindsey, et al.. (2000). Helicobacter pylori -Induced Mucosal Inflammation Is Th1 Mediated and Exacerbated in IL-4, But Not IFN-γ, Gene-Deficient Mice. The Journal of Immunology. 165(2). 1022–1029. 289 indexed citations

18.

Smythies, Lesley E., et al.. (2000). Quantitative analysis of Helicobacter pylori infection in a mouse model. Journal of Immunological Methods. 242(1-2). 67–78. 14 indexed citations

19.

Wilson, R. Alan, et al.. (1996). Impaired immunity and altered pulmonary responses in mice with a disrupted interferon‐γ receptor gene exposed to the irradiated Schistosoma mansoni vaccine. Immunology. 87(2). 275–282. 73 indexed citations

20.

Smythies, Lesley E., et al.. (1996). Kinetics and mechanism of effector focus formation in the lungs of mice vaccinated with irradiated cercariae of Schistosoma mansoni. Parasite Immunology. 18(7). 359–369. 30 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact