Lesley E. Smythies

5.8k citations

63 papers · 4.7k indexed · 2 hit papers · h-index 33

Immunology top 0.5%
Surgery top 2%
Molecular Biology top 10%
Genetics top 5%
Infectious Diseases top 5%

Co-authors: Phillip D. Smith Ronald H. Clements Marty T. Sellers Meg Mosteller‐Barnum Jan M. Orenstein Gang Meng William H. Benjamin Paul R. Harris
Topics: Immune Cell Function and Interaction (16 papers)Helicobacter pylori-related gastroenterology studies (15 papers)Immune cells in cancer (14 papers)
Cited by: Immunology Virology Parasitology
Journals: Journal of Biological Chemistry Circulation Journal of Clinical Investigation
Partner nations: United States Chile United Kingdom

In The Last Decade

Lesley E. Smythies

60 papers receiving 4.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity

2005 660 citations Lesley E. Smythies, Marty T. Sellers et al. Journal of Clinical Investigation profile →
Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity

2005 647 citations Lesley E. Smythies, Marty T. Sellers et al. Journal of Clinical Investigation profile →

Peers

Countries citing papers authored by Lesley E. Smythies

Since Specialization

Citations

This map shows the geographic impact of Lesley E. Smythies's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lesley E. Smythies with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lesley E. Smythies more than expected).

Fields of papers citing papers by Lesley E. Smythies

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lesley E. Smythies. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lesley E. Smythies. The network helps show where Lesley E. Smythies may publish in the future.

Co-authorship network of co-authors of Lesley E. Smythies

This figure shows the co-authorship network connecting the top 25 collaborators of Lesley E. Smythies. A scholar is included among the top collaborators of Lesley E. Smythies based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Lesley E. Smythies. Lesley E. Smythies is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Microbial remodeling of gut tryptophan metabolism and indole-3-lactate production regulate epithelial barrier repair and viral suppression in human and simian immunodeficiency virus infections 2025 ·Mucosal Immunology ·Clarissa Santos Rocha,Katie L. Alexander,Carolina Herrera,(unknown),Irina Grishina,Lauren A. Hirao,(unknown),Juan Arredondo,(unknown),(unknown),Anne Fenton,Maria L. Marco,David A. Mills,John C. Kappes,Lesley E. Smythies,Paul Ziprin,Sumathi Sankaran‐Walters,Phillip D. Smith,Satya Dandekar	6
2	Human intestinal stromal cells promote homeostasis in normal mucosa but inflammation in Crohn’s disease in a retinoic acid–deficient manner 2024 ·Mucosal Immunology ·Lesley E. Smythies,Olga V. Belyaeva,Katie L. Alexander,Diane Bimczok,(unknown),Carolina Serrano,(unknown),Marie Nearing,Lois C. Musgrove,(unknown),(unknown),(unknown),Kondal R. Kyanam Kabir Baig,David K. Crossman,Shajan Peter,Jamie A. Cannon,Charles O. Elson,Natalia Y. Kedishvili,Phillip D. Smith	0
3	Modulation of glycosyltransferase ST6Gal-I in gastric cancer-derived organoids disrupts homeostatic epithelial cell turnover 2020 ·Journal of Biological Chemistry ·Katie L. Alexander,Carolina Serrano,Asmi Chakraborty,Marie Nearing,Arnoldo Riquelme,Marcelo Garrido,Susan L. Bellis,Lesley E. Smythies,Phillip D. Smith	29
4	Cytomegalovirus promotes intestinal macrophage-mediated mucosal inflammation through induction of Smad7 2018 ·Mucosal Immunology ·(unknown),Lesley E. Smythies,Robert Grabski,Li Mao,Mary E. Ballestas,Masako Shimamura,Jim Sun,Jayleen Grams,Richard Stahl,Michael Niederweis,William J. Britt,Phillip D. Smith	29
5	CD4 regulatory T cells augment HIV-1 expression of polarized M1 and M2 monocyte derived macrophages 2017 ·Virology ·Tanya O. Robinson,Mingce Zhang,Christina Ochsenbauer,Lesley E. Smythies,Randy Q. Cron	15
6	Helicobacter pylori infection is associated with an altered gastric microbiota in children 2017 ·Mucosal Immunology ·(unknown),Ranjit Kumar,Carolina Serrano,Travis Ptacek,Elliot J. Lefkowitz,Casey D. Morrow,Degui Zhi,(unknown),Lesley E. Smythies,Paul R. Harris,Phillip D. Smith	73
7	Mother-to-Child HIV-1 Transmission Events Are Differentially Impacted by Breast Milk and Its Components from HIV-1-Infected Women 2015 ·PLoS ONE ·Ruizhong Shen,Jenna E. Achenbach,(unknown),(unknown),Jeremy Rahkola,(unknown),Lesley E. Smythies,Michelle S. McConnell,Mary Glenn Fowler,Phillip D. Smith,Edward N. Janoff	6
8	Human gastric epithelial cells contribute to gastric immune regulation by providing retinoic acid to dendritic cells 2014 ·Mucosal Immunology ·Diane Bimczok,John Y. Kao,(unknown),(unknown),Peter Mannon,Shajan Peter,C. Mel Wilcox,Klaus Mönkemüller,Paul R. Harris,Jayleen Grams,Richard Stahl,Phillip D. Smith,Lesley E. Smythies	44
9	Microbiota, the immune system, black moods and the brainâ€”melancholia updated 2014 ·Frontiers in Human Neuroscience ·Lesley E. Smythies,John Smythies	23
10	GP41-Specific Antibody Blocks Cell-Free HIV Type 1 Transcytosis through Human Rectal Mucosa and Model Colonic Epithelium 2010 ·The Journal of Immunology ·Ruizhong Shen,Ernesto Drelichman,Diane Bimczok,Christina Ochsenbauer,John C. Kappes,Jamie A. Cannon,Daniela Tudor,Morgane Bomsel,Lesley E. Smythies,Phillip D. Smith	50
11	IL-17 Activates the Canonical NF-κB Signaling Pathway in Autoimmune B Cells of BXD2 Mice To Upregulate the Expression of Regulators of G-Protein Signaling 16 2010 ·The Journal of Immunology ·Shutao Xie,Jun Li,(unknown),Qi Wu,PingAr Yang,Hui‐Chen Hsu,Lesley E. Smythies,John D. Mountz	89
12	Helicobacter pylori Gastritis in Children Is Associated With a Regulatory T-Cell Response 2008 ·Gastroenterology ·Paul R. Harris,Shelton W. Wright,Carolina Serrano,(unknown),Ignacio Duarte,Javiera Torres,Alfredo Peña,Antonio Rollán,Paola Viviani,Ernesto Guiraldes,Julia Schmitz,Robin G. Lorenz,Lea Novak,Lesley E. Smythies,Phillip D. Smith	190
13	Involvement of Dendritic Cells in the Pathogenesis of Inflammatory Bowel Disease 2006 ·Advances in experimental medicine and biology ·Francisco León,Lesley E. Smythies,Phillip D. Smith,Brian L. Kelsall	34
14	Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activitybreakdown → 2005 ·Journal of Clinical Investigation ·Lesley E. Smythies,Marty T. Sellers,Ronald H. Clements,Meg Mosteller‐Barnum,Gang Meng,William H. Benjamin,Jan M. Orenstein,Phillip D. Smith	647
15	Intestinal macrophages: unique effector cells of the innate immune system 2005 ·Immunological Reviews ·Phillip D. Smith,Christina Ochsenbauer‐Jambor,Lesley E. Smythies	169
16	Intestinal Macrophages Lack CD14 and CD89 and Consequently Are Down-Regulated for LPS- and IgA-Mediated Activities 2001 ·The Journal of Immunology ·Phillip D. Smith,Lesley E. Smythies,Meg Mosteller‐Barnum,Don A. Sibley,Michael W. Russell,Michael Merger,Marty T. Sellers,Jan M. Orenstein,Toshihide Shimada,Martin F. Graham,Hiromi Kubagawa	254
17	Helicobacter pylori -Induced Mucosal Inflammation Is Th1 Mediated and Exacerbated in IL-4, But Not IFN-γ, Gene-Deficient Mice 2000 ·The Journal of Immunology ·Lesley E. Smythies,Ken B. Waites,J. Russell Lindsey,Paul R. Harris,P Ghiara,Phillip D. Smith	289
18	Quantitative analysis of Helicobacter pylori infection in a mouse model 2000 ·Journal of Immunological Methods ·Lesley E. Smythies,(unknown),J. Russell Lindsey,P Ghiara,Phillip D. Smith,Ken B. Waites	14
19	Impaired immunity and altered pulmonary responses in mice with a disrupted interferon‐γ receptor gene exposed to the irradiated Schistosoma mansoni vaccine 1996 ·Immunology ·R. Alan Wilson,P S Coulson,Catherine J. Betts,(unknown),Lesley E. Smythies	73
20	Kinetics and mechanism of effector focus formation in the lungs of mice vaccinated with irradiated cercariae of Schistosoma mansoni 1996 ·Parasite Immunology ·Lesley E. Smythies,Catherine J. Betts,Patricia S. Coulson,(unknown),R. Alan Wilson	30

About Lesley E. Smythies

Lesley E. Smythies is a scholar working on Immunology, Virology and Small Animals, having authored 63 papers that have together received 4.7k indexed citations. Recurring topics across this work include Immune Cell Function and Interaction (16 papers), Helicobacter pylori-related gastroenterology studies (15 papers) and Immune cells in cancer (14 papers). The work is most often cited by research in Immunology (2.6k citations), Virology (380 citations) and Parasitology (383 citations). Lesley E. Smythies has collaborated with scholars based in United States, Chile and United Kingdom. Frequent co-authors include Phillip D. Smith, Ronald H. Clements, Marty T. Sellers, Meg Mosteller‐Barnum, Jan M. Orenstein, Gang Meng, William H. Benjamin, Paul R. Harris, Ruizhong Shen and R. Alan Wilson. Their work appears in journals such as Journal of Biological Chemistry, Circulation and Journal of Clinical Investigation.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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