Hiroaki Sakurai

10.7k total citations · 1 hit paper
207 papers, 9.0k citations indexed

About

Hiroaki Sakurai is a scholar working on Molecular Biology, Oncology and Cancer Research. According to data from OpenAlex, Hiroaki Sakurai has authored 207 papers receiving a total of 9.0k indexed citations (citations by other indexed papers that have themselves been cited), including 118 papers in Molecular Biology, 62 papers in Oncology and 58 papers in Cancer Research. Recurrent topics in Hiroaki Sakurai's work include NF-κB Signaling Pathways (46 papers), Cytokine Signaling Pathways and Interactions (19 papers) and Immune Response and Inflammation (19 papers). Hiroaki Sakurai is often cited by papers focused on NF-κB Signaling Pathways (46 papers), Cytokine Signaling Pathways and Interactions (19 papers) and Immune Response and Inflammation (19 papers). Hiroaki Sakurai collaborates with scholars based in Japan, United States and Thailand. Hiroaki Sakurai's co-authors include Ikuo Saiki, Takahisa Sugita, Hidetaka Miyoshi, Keiichi Koizumi, Wataru Toriumi, Hiroaki Chiba, Shunsuke Suzuki, Yue Zhou, Noritaka Kawasaki and Junko Mizukami and has published in prestigious journals such as Journal of Biological Chemistry, Angewandte Chemie International Edition and Journal of Clinical Investigation.

In The Last Decade

Hiroaki Sakurai

200 papers receiving 8.8k citations

Hit Papers

IκB Kinases Phosphorylate NF-κB p65 Subunit on Serine 536... 1999 2026 2008 2017 1999 200 400 600
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. IκB Kinases Phosphorylate NF-κB p65 Subunit on Serine 536 in the Transactivation Domain
    1999 732 citations Hiroaki Sakurai, Takahisa Sugita et al. Journal of Biological Chemistry profile →

Peers

Hiroaki Sakurai
Kazuo Umezawa Japan
Vinay Tergaonkar Singapore
Heike L. Pahl Germany
John DiGiovanni United States
Shrikant Anant United States
Tse‐Hua Tan United States
Anthony M. Manning United States
Paul J. Chiao United States
Mayumi Ono Japan
Ingrid Herr Germany
Kazuo Umezawa Japan
Hiroaki Sakurai
Citations per year, relative to Hiroaki Sakurai Hiroaki Sakurai (= 1×) peers Kazuo Umezawa

Countries citing papers authored by Hiroaki Sakurai

Since Specialization
Citations

This map shows the geographic impact of Hiroaki Sakurai's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hiroaki Sakurai with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hiroaki Sakurai more than expected).

Fields of papers citing papers by Hiroaki Sakurai

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hiroaki Sakurai. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hiroaki Sakurai. The network helps show where Hiroaki Sakurai may publish in the future.

Co-authorship network of co-authors of Hiroaki Sakurai

This figure shows the co-authorship network connecting the top 25 collaborators of Hiroaki Sakurai. A scholar is included among the top collaborators of Hiroaki Sakurai based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Hiroaki Sakurai. Hiroaki Sakurai is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Nguyen, Khanh Cong, Yue Zhou, Satoru Yokoyama, et al.. (2025). Allosteric SHP2 inhibitors suppress lung cancer cell migration by inhibiting non-canonical activation of EphA2 via the ERK-RSK signaling pathway. Scientific Reports. 15(1). 36926–36926.
2.
Kawabata, Hiroshi, et al.. (2025). Clustered peptide regulating the multivalent interaction between RANK and TRAF6 inhibits osteoclastogenesis by fine-tuning signals. Communications Biology. 8(1). 643–643. 1 indexed citations
3.
Zhang, Fang, Yue Zhou, Satoru Yokoyama, et al.. (2025). Stress Response Kinase MK2 Induces Non-canonical Activation of EphA2 in <i>EML4-ALK</i> Lung Cancer Cells. Biological and Pharmaceutical Bulletin. 48(2). 172–176.
4.
Mori, Yuta, et al.. (2024). Association between internet use and self-rated health of patients living with diabetes in the community. Digital Health. 10. 599904081–599904081.
5.
Zhou, Yue, et al.. (2023). Controllable conformation and reactivity of bicyclic α-methylene cyclopentanones and their NF-κB pathway inhibitory activity. Organic & Biomolecular Chemistry. 21(22). 4656–4660. 1 indexed citations
6.
Zhou, Yue, et al.. (2023). Cellular stress induces non-canonical activation of the receptor tyrosine kinase EphA2 through the p38-MK2-RSK signaling pathway. Journal of Biological Chemistry. 299(5). 104699–104699. 10 indexed citations
7.
Kato, Shinichiro, et al.. (2019). Rational Combination Therapy for Melanoma with Dinaciclib by Targeting BAK-Dependent Cell Death. Molecular Cancer Therapeutics. 19(2). 627–636. 10 indexed citations
8.
Tanaka, Tomohiro, et al.. (2019). Negative feedback regulation of ErbB4 tyrosine kinase activity by ERK-mediated non-canonical phosphorylation. Biochemical and Biophysical Research Communications. 514(2). 456–461. 5 indexed citations
9.
Leu, Yann-Lii, Mei‐Ling Cheng, Ching-Chuan Liu, et al.. (2017). Anti-enterovirus 71 activities of Melissa officinalis extract and its biologically active constituent rosmarinic acid. Scientific Reports. 7(1). 12264–12264. 32 indexed citations
10.
Kawasaki, Yuki, Chul Min Park, Tomohiro Tanaka, et al.. (2016). Feedback control of ErbB2 via ERK-mediated phosphorylation of a conserved threonine in the juxtamembrane domain. Scientific Reports. 6(1). 31502–31502. 21 indexed citations
11.
Saiki, Ikuo, Keiichi Koizumi, Hirozo Goto, et al.. (2013). The Long-Term Effects of a Kampo Medicine, Juzentaihoto, on Maintenance of Antibody Titer in Elderly People after Influenza Vaccination. Evidence-based Complementary and Alternative Medicine. 2013. 1–8. 15 indexed citations
12.
Lirdprapamongkol, Kriengsak, Hiroaki Sakurai, Sherif Abdelhamed, et al.. (2013). Chrysin overcomes TRAIL resistance of cancer cells through Mcl-1 downregulation by inhibiting STAT3 phosphorylation. International Journal of Oncology. 43(1). 329–337. 63 indexed citations
13.
Oka, Hiroshi, Hirozo Goto, Keiichi Koizumi, et al.. (2011). Cinnamaldehyde and paeonol increase HIF-1α activity in proximal tubular epithelial cells under hypoxia. 28(3). 149–157. 1 indexed citations
14.
Koizumi, Keiichi, et al.. (2010). Methanol extract of Polygonati Rhizoma enhances the tube formation of rat lymphatic endothelial cells. 27(2). 59–65. 2 indexed citations
15.
Hasegawa, Hideki, et al.. (2010). Distinctive Flavor and Strong Antifungal Activity in a Sourdough Bread Made Using Unique lactic Acid Bacteria Obtained from a Sugar Factory. Nippon Shokuhin Kagaku Kogaku Kaishi. 57(2). 85–90. 3 indexed citations
16.
Koizumi, Keiichi, Yurika Saitoh, T. Minami, et al.. (2009). Role of CX3CL1/Fractalkine in Osteoclast Differentiation and Bone Resorption. The Journal of Immunology. 183(12). 7825–7831. 115 indexed citations
17.
18.
Sakurai, Hiroaki, Min‐Kyung Choo, Atsushi CHINO, et al.. (2006). Antimetastatic and immunostimulatory properties of fermented brown rice. 23(3). 112–116. 3 indexed citations
19.
Yamamoto, Masahiro, Shintaro Sato, Tatsuya Saitoh, et al.. (2006). Cutting Edge: Pivotal Function of Ubc13 in Thymocyte TCR Signaling. The Journal of Immunology. 177(11). 7520–7524. 71 indexed citations
20.
Sakurai, Hiroaki, et al.. (1997). Suppression of NF-κB and AP-1 activation by glucocorticoids in experimental glomerulonephritis in rats: molecular mechanisms of anti-nephritic action. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1362(2-3). 252–262. 57 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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