Paul J. Chiao

13.8k citations

135 papers · 11.2k indexed · 3 hit papers · h-index 60

Molecular Biology top 0.5%
Cancer Research top 0.2%
Oncology top 0.5%
Immunology top 1%
Epidemiology top 5%

Co-authors: James L. Abbruzzese Douglas B. Evans Peng Huang Guido M. Sclabas Bailu Peng Shigeki Miyamoto Jiangong Niu Weixin Wang
Topics: NF-κB Signaling Pathways (44 papers)Pancreatic and Hepatic Oncology Research (27 papers)Immune Response and Inflammation (20 papers)
Cited by: Cancer Research Oncology Molecular Biology
Journals: Proceedings of the National Academy of Sciences Journal of Biological Chemistry Journal of Clinical Investigation
Partner nations: United States China Japan

In The Last Decade

Paul J. Chiao

133 papers receiving 11.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by β-phenylethyl isothiocyanate

2006 903 citations Dunyaporn Trachootham, Yan Zhou et al. Cancer Cell profile →
The nuclear factor-kappa B RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells.

1999 564 citations Weixin Wang, James L. Abbruzzese et al. PubMed profile →
Suppression of the SLC7A11/glutathione axis causes synthetic lethality in KRAS-mutant lung adenocarcinoma

2019 287 citations Paul J. Chiao et al. profile →

Peers

Countries citing papers authored by Paul J. Chiao

Since Specialization

Citations

This map shows the geographic impact of Paul J. Chiao's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Paul J. Chiao with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Paul J. Chiao more than expected).

Fields of papers citing papers by Paul J. Chiao

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Paul J. Chiao. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Paul J. Chiao. The network helps show where Paul J. Chiao may publish in the future.

Co-authorship network of co-authors of Paul J. Chiao

This figure shows the co-authorship network connecting the top 25 collaborators of Paul J. Chiao. A scholar is included among the top collaborators of Paul J. Chiao based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Paul J. Chiao. Paul J. Chiao is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	IGFBP2 Activates the NF-κB Pathway to Drive Epithelial–Mesenchymal Transition and Invasive Character in Pancreatic Ductal Adenocarcinoma 2016 ·Cancer Research ·Song Gao,Yan Sun,(unknown),Limei Hu,Yuexin Liu,Corrine Ying Xuan Chua,Lynette M. Phillips,He Ren,Jason B. Fleming,Huamin Wang,Paul J. Chiao,Jihui Hao,Wei Zhang	88
2	Transforming Growth Factor-β Limits Secretion of Lumican by Activated Stellate Cells within Primary Pancreatic Adenocarcinoma Tumors 2016 ·Clinical Cancer Research ·Ya’an Kang,David Roife,Yeon‐Ju Lee,(unknown),Rei Suzuki,Jianhua Ling,(unknown),Xinqun Li,Bingbing Dai,Michael Pratt,Mark J. Truty,Deyali Chatterjee,Huamin Wang,Ryan M. Thomas,Yu Wang,Eugene J. Koay,Paul J. Chiao,Matthew H. G. Katz,Jason B. Fleming	29
3	FBW7 (F-box and WD Repeat Domain-Containing 7) Negatively Regulates Glucose Metabolism by Targeting the c-Myc/TXNIP (Thioredoxin-Binding Protein) Axis in Pancreatic Cancer 2016 ·Clinical Cancer Research ·Shunrong Ji,Yi Qin,Chen Liang,Run Huang,Si Shi,Jiang Liu,Kaizhou Jin,Dingkong Liang,Wenyan Xu,Bo Zhang,Liang Liu,Chen Liu,Jin Xu,Quanxing Ni,Paul J. Chiao,Min Li,Xianjun Yu	76
4	IL1 Receptor Antagonist Inhibits Pancreatic Cancer Growth by Abrogating NF-κB Activation 2015 ·Clinical Cancer Research ·Zhuonan Zhuang,Huai‐Qiang Ju,Mitzi Aguilar,(unknown),Hao Li,Tomonori Iida,Harold Lee,(unknown),Haijun Zhou,Jianhua Ling,Zhongkui Li,Jie Fu,Min Wu,Min Li,Davide Melisi,Yoichiro Iwakura,Kesen Xu,Jason B. Fleming,Paul J. Chiao	95
5	Mechanisms of Overcoming Intrinsic Resistance to Gemcitabine in Pancreatic Ductal Adenocarcinoma through the Redox Modulation 2014 ·Molecular Cancer Therapeutics ·Huai‐Qiang Ju,Takeshi Gocho,Mitzi Aguilar,Min Wu,(unknown),Jie Fu,Katsuhiko Yanaga,Peng Huang,Paul J. Chiao	119
6	EGFR-Induced and PKCε Monoubiquitylation-Dependent NF-κB Activation Upregulates PKM2 Expression and Promotes Tumorigenesis 2012 ·Molecular Cell ·Weiwei Yang,Yan Xia,Yu Cao,Yanhua Zheng,Wen Bu,Lin Zhang,M. James You,Mei Yee Koh,Gilbert J. Cote,Kenneth Aldape,Yi Li,Inder M. Verma,Paul J. Chiao,Zhimin Lu	219
7	Anti-VEGF Treatment–Resistant Pancreatic Cancers Secrete Proinflammatory Factors That Contribute to Malignant Progression by Inducing an EMT Cell Phenotype 2011 ·Clinical Cancer Research ·Carmine Carbone,Tania Moccia,Cihui Zhu,(unknown),Alfredo Budillon,Paul J. Chiao,James L. Abbruzzese,Davide Melisi	80
8	The Biphasic Role of NF-κB in Progression and Chemoresistance of Ovarian Cancer 2011 ·Clinical Cancer Research ·Gong Yang,Xue Xiao,Daniel Rosen,Xi Cheng,Xiaohua Wu,Bin Chang,Guangzhi Liu,Fengxia Xue,Imelda Mercado‐Uribe,Paul J. Chiao,Du Xiang,Jinsong Liu	66
9	Oral Poly(ADP-Ribose) Polymerase-1 Inhibitor BSI-401 Has Antitumor Activity and Synergizes with Oxaliplatin against Pancreatic Cancer, Preventing Acute Neurotoxicity 2009 ·Clinical Cancer Research ·Davide Melisi,Valeria Ossovskaya,Cihui Zhu,Roberta Rosa,Jianhua Ling,Patrick M. Dougherty,Barry M. Sherman,James L. Abbruzzese,Paul J. Chiao	32
10	TrkBT1 Induces Liver Metastasis of Pancreatic Cancer Cells by Sequestering Rho GDP Dissociation Inhibitor and Promoting RhoA Activation 2009 ·Cancer Research ·Zhongkui Li,Zhe Chang,(unknown),Ya’an Kang,Qianghua Xia,Cihui Zhu,Jason B. Fleming,Douglas B. Evans,Paul J. Chiao	45
11	LY2109761, a novel transforming growth factor β receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis 2008 ·Molecular Cancer Therapeutics ·Davide Melisi,Satoshi Ishiyama,Guido M. Sclabas,Jason B. Fleming,Qianghua Xia,Giampaolo Tortora,James L. Abbruzzese,Paul J. Chiao	262
12	The novel poly(ADP-ribose) polymerase (PARP) -1 Inhibitor, BSI-401, has antitumor activity and potentiates oxaliplatin cytotoxic activity in human pancreatic cancer 2007 ·Molecular Cancer Therapeutics ·Davide Melisi,Valeria Ossovskaya,Barry M. Sherman,James L. Abbruzzese,Paul J. Chiao	1
13	Potential Role of Jun Activation Domain–Binding Protein 1 as a Negative Regulator of p27kip1 in Pancreatic Adenocarcinoma 2006 ·Cancer Research ·Maria A. Kouvaraki,Anita L. Korapati,George Z. Rassidakis,Ling Tian,Qingxiu Zhang,Paul J. Chiao,Linus Ho,Douglas B. Evans,François X. Claret	55
14	Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by β-phenylethyl isothiocyanatebreakdown → 2006 ·Cancer Cell ·Dunyaporn Trachootham,Yan Zhou,Hui Zhang,Yusuke Demizu,Chen Zhao,Hélène Pelicano,Paul J. Chiao,Geetha Achanta,Ralph B. Arlinghaus,Jinsong Liu,Peng Huang	903
15	Selective killing of oncogenic transformed cells through ROS-mediated mechanism by β-phenylethyl isothiocyanates 2006 ·Cancer Research ·Dunyaporn Trachootham,Yan Zhou,Hélène Pelicano,Paul J. Chiao,Jinsong Liu,Peng Huang	2
16	In vitro Modeling of Human Pancreatic Duct Epithelial Cell Transformation Defines Gene Expression Changes Induced by K- ras Oncogenic Activation in Pancreatic Carcinogenesis 2005 ·Cancer Research ·(unknown),Jiangong Niu,Ming Li,Paul J. Chiao,Ming‐Sound Tsao	94
17	Bortezomib Inhibits PKR-Like Endoplasmic Reticulum (ER) Kinase and Induces Apoptosis via ER Stress in Human Pancreatic Cancer Cells 2005 ·Cancer Research ·Steffan T. Nawrocki,Jennifer S. Carew,Kenneth Dunner,Lawrence Boise,Paul J. Chiao,Peng Huang,James L. Abbruzzese,David J. McConkey	260
18	NF-κB Activation Is Not Required for Chlamydia trachomatis Inhibition of Host Epithelial Cell Apoptosis 2005 ·The Journal of Immunology ·Yangming Xiao,Youmin Zhong,Heng Su,Zhiguang Zhou,Paul J. Chiao,Guangming Zhong	43
19	NF-κB and AP-1 Connection: Mechanism of NF-κB-Dependent Regulation of AP-1 Activity 2004 ·Molecular and Cellular Biology ·Shuichi Fujioka,Jiangong Niu,Christian Schmidt,Guido M. Sclabas,Bailu Peng,Tadashi Uwagawa,Zhongkui Li,Douglas B. Evans,James L. Abbruzzese,Paul J. Chiao	370
20	Induction of p21waf1 expression and growth inhibition by transforming growth factor beta involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells. 1997 ·PubMed ·Ana M. Grau,Ling Zhang,Weixin Wang,Sanbao Ruan,Douglas B. Evans,James L. Abbruzzese,Wei Zhang,Paul J. Chiao	121

About Paul J. Chiao

Paul J. Chiao is a scholar working on Cancer Research, Oncology and Immunology, having authored 135 papers that have together received 11.2k indexed citations. Recurring topics across this work include NF-κB Signaling Pathways (44 papers), Pancreatic and Hepatic Oncology Research (27 papers) and Immune Response and Inflammation (20 papers). The work is most often cited by research in Cancer Research (4.0k citations), Oncology (3.7k citations) and Molecular Biology (7.1k citations). Paul J. Chiao has collaborated with scholars based in United States, China and Japan. Frequent co-authors include James L. Abbruzzese, Douglas B. Evans, Peng Huang, Guido M. Sclabas, Bailu Peng, Shigeki Miyamoto, Jiangong Niu, Weixin Wang, Christian Schmidt and Shuichi Fujioka. Their work appears in journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Clinical Investigation.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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