Ken J. Ishii

33.4k total citations · 8 hit papers
296 papers, 24.9k citations indexed

About

Ken J. Ishii is a scholar working on Immunology, Molecular Biology and Epidemiology. According to data from OpenAlex, Ken J. Ishii has authored 296 papers receiving a total of 24.9k indexed citations (citations by other indexed papers that have themselves been cited), including 202 papers in Immunology, 64 papers in Molecular Biology and 53 papers in Epidemiology. Recurrent topics in Ken J. Ishii's work include Immune Response and Inflammation (133 papers), Immunotherapy and Immune Responses (72 papers) and interferon and immune responses (63 papers). Ken J. Ishii is often cited by papers focused on Immune Response and Inflammation (133 papers), Immunotherapy and Immune Responses (72 papers) and interferon and immune responses (63 papers). Ken J. Ishii collaborates with scholars based in Japan, United States and France. Ken J. Ishii's co-authors include Shizuo Akira, Cevayir Coban, Taro Kawai, Osamu Takeuchi, Shintaro Sato, Fumihiko Takeshita, Dennis M. Klinman, Satoshi Uematsu, Hiroki Kato and Masahiro Yamamoto and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and The Lancet.

In The Last Decade

Ken J. Ishii

287 papers receiving 24.5k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

2006 3.0k citations Osamu Takeuchi, Masahiro Yamamoto et al. profile →
IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

2005 2.1k citations Taro Kawai, Cevayir Coban et al. profile →
Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

2004 837 citations Taro Kawai, Ken J. Ishii et al. profile →
Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response

2009 675 citations Tatsuya Saitoh, Naonobu Fujita et al. Proceedings of the National Academy of Sciences profile →
A Toll-like receptor–independent antiviral response induced by double-stranded B-form DNA

2005 642 citations Ken J. Ishii, Cevayir Coban et al. profile →
Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5

2008 588 citations Ken J. Ishii, Shizuo Akira et al. profile →
TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines

2008 513 citations Ken J. Ishii, Taro Kawai et al. profile →
Challenges in developing personalized neoantigen cancer vaccines

2023 129 citations Ken J. Ishii et al. profile →

Peers

Countries citing papers authored by Ken J. Ishii

Since Specialization

Citations

This map shows the geographic impact of Ken J. Ishii's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ken J. Ishii with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ken J. Ishii more than expected).

Fields of papers citing papers by Ken J. Ishii

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ken J. Ishii. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ken J. Ishii. The network helps show where Ken J. Ishii may publish in the future.

Co-authorship network of co-authors of Ken J. Ishii

This figure shows the co-authorship network connecting the top 25 collaborators of Ken J. Ishii. A scholar is included among the top collaborators of Ken J. Ishii based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ken J. Ishii. Ken J. Ishii is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Oncolytic adenovirus serotype 35 mediated tumor growth suppression via efficient activation of antitumor immunity 2025 ·Journal for ImmunoTherapy of Cancer ·(unknown), (unknown), Masashi Tachibana, Ken J. Ishii, Fuminori Sakurai, Hiroyuki Mizuguchi	0
2	5,6-dimethylxanthenone-4-acetic acid (DMXAA), a partial STING agonist, competes for human STING activation 2024 ·Frontiers in Immunology ·Burcu Temizoz, (unknown), (unknown), Tomoya Hayashi, Kouji Kobiyama, Michelle Sue Jann Lee, (unknown), Erdal Sağ, Atsushi Kumanogoh, Masahiro Yamamoto, Mayda Gürsel, Seza Özen, Etsushi Kuroda, Cevayir Coban, Ken J. Ishii	14
3	Discovery of DS44470011: An oral hypoxia-inducible factor prolyl hydroxylase inhibitor for the treatment of renal anemia 2024 ·Bioorganic & Medicinal Chemistry Letters ·Takeshi Fukuda, Takeshi Kuribayashi, (unknown), Koji Sasaki, Takashi Tsuji, Y. Niitsu, Ken J. Ishii, (unknown), Daichi Baba, Shuichiro Ito, Naoki Tanaka	2
4	Acute malaria suppresses the B lymphocytic niche in the bone marrow through the alteration of CXCL12-abundant reticular cells 2024 ·International Immunology ·Michelle Sue Jann Lee, (unknown), C. Zorrilla, Yoshiki Omatsu, Takashi Nagasawa, (unknown), Atsushi Iwama, Ken J. Ishii, Cevayir Coban	2
5	Identification of a Self-Assembling Small-Molecule Cancer Vaccine Adjuvant with an Improved Toxicity Profile 2023 ·Journal of Medicinal Chemistry ·(unknown), Naotaka Noda, (unknown), (unknown), Tomoya Hayashi, K. Hiraga, Haruka Momose, Wenhao Li, Lang Zhao, Takuo Mizukami, Ken J. Ishii, Yanmei Li, Motonari Uesugi	1
6	Anti-Inflammatory Role of TRPV4 in Human Macrophages 2023 ·ImmunoHorizons ·(unknown), (unknown), Hiroko Kato, Motoki Nakamura, Akimichi Morita, Masayuki Takaishi, Kaori Saito, (unknown), (unknown), Makoto Tominaga, Ken J. Ishii, Fumitaka Fujita	8
7	Discovery of Self‐Assembling Small Molecules as Vaccine Adjuvants 2020 ·Angewandte Chemie International Edition ·(unknown), (unknown), (unknown), Naotaka Noda, Hiroki Yoshida, (unknown), (unknown), Ippei Takashima, Yoshiyuki Mizuhata, (unknown), Tetsuya Ogawa, Naoya Nishimura, Daniel M. Packwood, Norihiro Tokitoh, Hiroki Kurata, Sho Yamasaki, Ken J. Ishii, Motonari Uesugi	14
8	Characteristic of K3 (CpG-ODN) as a Transcutaneous Vaccine Formulation Adjuvant 2020 ·Pharmaceutics ·(unknown), Sachiko Hirobe, (unknown), (unknown), Ying-Shu Quan, Fumio Kamiyama, Ken J. Ishii, Mizuho Nagao, Takao Fujisawa, Masashi Tachibana, Naoki Okada	14
9	The protective effects of nasal PcrV‐CpG oligonucleotide vaccination against Pseudomonas aeruginosa pneumonia 2018 ·Microbiology and Immunology ·Yoshifumi Naito, (unknown), Mao Kinoshita, (unknown), Masaru Shimizu, (unknown), Kiyoshi Moriyama, Ken J. Ishii, Teiji Sawa	24
10	Selective Inhibition of ADAM28 Suppresses Lung Carcinoma Cell Growth and Metastasis 2018 ·Molecular Cancer Therapeutics ·Satsuki Mochizuki, Masayuki Shimoda, Hitoshi Abe, (unknown), (unknown), Noriko Aramaki‐Hattori, Ken J. Ishii, Hideki Ueno, (unknown), (unknown), Yasunori Okada	10
11	Oncolytic Reovirus Inhibits Immunosuppressive Activity of Myeloid-Derived Suppressor Cells in a TLR3-Dependent Manner 2018 ·The Journal of Immunology ·Yuki Katayama, Masashi Tachibana, (unknown), (unknown), (unknown), (unknown), Kouji Kobiyama, Ken J. Ishii, Shizuo Akira, Hiroyuki Mizuguchi, Fuminori Sakurai	34
12	An Antigen-Free, Plasmacytoid Dendritic Cell–Targeting Immunotherapy To Bolster Memory CD8+ T Cells in Nonhuman Primates 2018 ·The Journal of Immunology ·(unknown), Takuya Yamamoto, Yayoi Natsume‐Kitatani, Tomohiro Kanuma, Eiko Moriishi, Kouji Kobiyama, Kenji Mizuguchi, Yasuhiro Yasutomi, Ken J. Ishii	10
13	RAE1 Ligands for the NKG2D Receptor Are Regulated by STING-Dependent DNA Sensor Pathways in Lymphoma 2014 ·Cancer Research ·(unknown), Nina Le Bert, Samantha S.W. Ho, Yu J. Shen, (unknown), Gordon M. Xiong, J. Ludovic Croxford, Christine X. Koo, Ken J. Ishii, Shizuo Akira, David H. Raulet, Stephan Gasser	128
14	The Early Activation ofCD8+T Cells Is Dependent on Type I IFN Signaling following Intramuscular Vaccination of Adenovirus Vector 2014 ·BioMed Research International ·(unknown), Masashi Tachibana, (unknown), Masaki Shoji, Fuminori Sakurai, Kenji Kawabata, Kouji Kobiyama, Ken J. Ishii, Shizuo Akira, Hiroyuki Mizuguchi	7
15	Hemozoin as a novel adjuvant for inactivated whole virion influenza vaccine 2014 ·Vaccine ·Ryuta Uraki, Subash C. Das, Masato Hatta, Maki Kiso, Kiyoko Iwatsuki‐Horimoto, Makoto Ozawa, Cevayir Coban, Ken J. Ishii, Yoshihiro Kawaoka	12
16	Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response breakdown → 2009 ·Proceedings of the National Academy of Sciences ·Tatsuya Saitoh, Naonobu Fujita, Takuya Hayashi, (unknown), Takashi Satoh, Hanna Lee, Kohichi Matsunaga, Shun Kageyama, Hiroko Omori, Takeshi Noda, Naoki Yamamoto, Taro Kawai, Ken J. Ishii, Osamu Takeuchi, Tamotsu Yoshimori, Shizuo Akira	675
17	Extrachromosomal Histone H2B Mediates Innate Antiviral Immune Responses Induced by Intracellular Double-Stranded DNA 2009 ·Journal of Virology ·Kouji Kobiyama, Fumihiko Takeshita, Nao Jounai, Asako Sakaue‐Sawano, Atsushi Miyawaki, Ken J. Ishii, Taro Kawai, Shin Sasaki, Hisashi Hirano, Norihisa Ishii, Kenji Okuda, Koichi Suzuki	44
18	The Atg5–Atg12 conjugate associates with innate antiviral immune responses 2007 ·Proceedings of the National Academy of Sciences ·Nao Jounai, Fumihiko Takeshita, Kouji Kobiyama, Asako Sakaue‐Sawano, Atsushi Miyawaki, Ke-Qin Xin, Ken J. Ishii, Taro Kawai, Shizuo Akira, Koichi Suzuki, Kenji Okuda	486
19	Toll-Like Receptor 9 Signaling Activates NF-κB through IFN Regulatory Factor-8/IFN Consensus Sequence Binding Protein in Dendritic Cells 2004 ·The Journal of Immunology ·Hideki Tsujimura, Tomohiko Tamura, Hee Jeong Kong, Akira Nishiyama, Ken J. Ishii, Dennis M. Klinman, Keiko Ozato	124
20	Precise target strength pattern measurement in an indoor tank. 1997 ·Journal of the Acoustical Society of Japan (E) ·Kouichi Sawada, (unknown), Ken J. Ishii	7

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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