Helena Edlund

32.1k citations

135 papers · 24.0k indexed · 13 hit papers · h-index 78

Molecular Biology top 0.1%
Surgery top 0.05%
Genetics top 0.05%
Endocrinology, Diabetes and Metabolism top 0.1%
Cellular and Molecular Neuroscience top 0.5%

Co-authors: Thomas M. Jessell Jörgen Jönsson Lena Carlsson Ulf Ahlgren Helena Ohlsson Samuel L. Pfaff Michael Walker Stefan Thor
Topics: Pancreatic function and diabetes (66 papers)Congenital heart defects research (23 papers)Developmental Biology and Gene Regulation (23 papers)
Cited by: Developmental Neuroscience Genetics Endocrinology, Diabetes and Metabolism
Journals: Nature Science Cell
Partner nations: Sweden United States United Kingdom

In The Last Decade

Helena Edlund

135 papers receiving 23.4k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Insulin-promoter-factor 1 is required for pancreas development in mice

1994 1.5k citations Helena Edlund et al. Nature profile →
Notch signalling controls pancreatic cell differentiation

1999 930 citations Åsa Apelqvist, Hao Li et al. Nature profile →
Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes

1994 893 citations Helena Edlund, Thomas M. Jessell et al. profile →
β-Cell-specific inactivation of the mouseIpf1/Pdx1 gene results in loss of the β-cell phenotype and maturity onset diabetes

1998 743 citations Ulf Ahlgren, Helena Edlund et al. profile →
IPF1, a homeodomain-containing transactivator of the insulin gene.

1993 737 citations Helena Edlund et al. profile →
Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord

1994 724 citations Stefan Norlin, Helena Edlund et al. profile →
Cell-Specific Expression of the Rat Insulin Gene: Evidence for Role of Two Distinct 5′ Flanking Elements

1985 654 citations Helena Edlund, Michael Walker et al. profile →
Requirement for LIM Homeobox Gene Isl1 in Motor Neuron Generation Reveals a Motor Neuron– Dependent Step in Interneuron Differentiation

1996 651 citations Helena Edlund, Thomas M. Jessell et al. profile →
Insulin gene enhancer binding protein Isl-1 is a member of a novel class of proteins containing both a homeo-and a Cys–His domain

1990 589 citations Olof Karlsson, Stefan Thor et al. Nature profile →
Cell-specific expression controlled by the 5′-flanking region of insulin and chymotrypsin genes

1983 584 citations Michael Walker, Helena Edlund et al. Nature profile →
Early Stages of Motor Neuron Differentiation Revealed by Expression of Homeobox Gene Islet-1

1992 576 citations Johan Ericson, Stefan Thor et al. profile →
Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells

1997 558 citations Ulf Ahlgren, Thomas M. Jessell et al. Nature profile →
Pdx1 Maintains β Cell Identity and Function by Repressing an α Cell Program

2014 312 citations Tao Gao, Brian D. McKenna et al. Cell Metabolism profile →

Peers

Countries citing papers authored by Helena Edlund

Since Specialization

Citations

This map shows the geographic impact of Helena Edlund's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Helena Edlund with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Helena Edlund more than expected).

Fields of papers citing papers by Helena Edlund

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Helena Edlund. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Helena Edlund. The network helps show where Helena Edlund may publish in the future.

Co-authorship network of co-authors of Helena Edlund

This figure shows the co-authorship network connecting the top 25 collaborators of Helena Edlund. A scholar is included among the top collaborators of Helena Edlund based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Helena Edlund. Helena Edlund is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	O304 ameliorates hyperglycemia in mice by dually promoting muscle glucose effectiveness and preserving β-cell function 2023 ·Communications Biology ·Stefan Norlin,Jan Axelsson,Madelene Ericsson,Helena Edlund	4
2	AMPK activator O304 improves metabolic and cardiac function, and exercise capacity in aged mice 2021 ·Communications Biology ·Madelene Ericsson,Pär Steneberg,Rakel Nyrén,Helena Edlund	21
3	The anterior chamber of the eye is a transplantation site that supports and enables visualisation of beta cell development in mice 2016 ·Diabetologia ·Yusuf Ali,Juan Díez,Lars Selander,Xiaofeng Zheng,Helena Edlund,Per‐Olof Berggren	11
4	Insulin-degrading enzyme prevents α-synuclein fibril formation in a nonproteolytical manner 2015 ·Scientific Reports ·Sandeep Sharma,Erik Chorell,Pär Steneberg,(unknown),Helena Edlund,Pernilla Wittung‐Stafshede	92
5	Pdx1 Maintains β Cell Identity and Function by Repressing an α Cell Programbreakdown → 2014 ·Cell Metabolism ·Tao Gao,Brian D. McKenna,Changhong Li,Maximilian Reichert,James Nguyen,Tarjinder Singh,Chenghua Yang,(unknown),Nicolai M. Doliba,Tingting Zhang,Doris A. Stoffers,Helena Edlund,(unknown),Roland Stein,Ben Z. Stanger	312
6	MFng Is Dispensable for Mouse Pancreas Development and Function 2009 ·Molecular and Cellular Biology ·Per H. Svensson,Ingela Bergqvist,Stefan Norlin,Helena Edlund	21
7	Gene array identification of Ipf1/Pdx1-/-regulated genes in pancreatic progenitor cells 2007 ·BMC Developmental Biology ·Per Svensson,Cecilia Williams,Joakim Lundeberg,Patrik Rydén,Ingela Bergqvist,Helena Edlund	24
8	Convergent Wnt and FGF signaling at the gastrula stage induce the formation of the isthmic organizer 2006 ·Mechanisms of Development ·(unknown),Ulrika Nordström,Cédric Patthey,Helena Edlund	15
9	sox4b is a key player of pancreatic α cell differentiation in zebrafish 2005 ·Developmental Biology ·Anastasia Mavropoulos,Nathalie Devos,Frédéric Biemar,Elisabetta Zecchin,Francesco Argenton,Helena Edlund,Patrick Motté,Joseph Martial,Bernard Peers	65
10	Retinoic acid signalling specifies intermediate character in the developing telencephalon 2004 ·Development ·(unknown),(unknown),Blake C. Beehler,Thomas M. Jessell,Helena Edlund,Lena Gunhaga	62
11	Increased islet apoptosis in Pdx1+/– mice 2003 ·Journal of Clinical Investigation ·James D. Johnson,Noreen Ahmed,Dan S. Luciani,Zhiqiang Han,Hung D. Tran,Jun Fujita,Stanley Misler,Helena Edlund,Kenneth S. Polonsky	281
12	Pancreatic organogenesis — developmental mechanisms and implications for therapy 2002 ·Nature Reviews Genetics ·Helena Edlund	386
13	Persistent Expression of Hlxb9 in the Pancreatic Epithelium Impairs Pancreatic Development 2001 ·Developmental Biology ·Hao Li,Helena Edlund	63
14	Notch signalling controls pancreatic cell differentiationbreakdown → 1999 ·Nature ·Åsa Apelqvist,Hao Li,Lukas Sommer,Paul Beatus,David J. Anderson,Tasuku Honjo,Martin Hrabě de Angelis,Urban Lendahl,Helena Edlund	930
15	Assignment of Early Caudal Identity to Neural Plate Cells by a Signal from Caudal Paraxial Mesoderm 1997 ·Neuron ·Jonas Muhr,Thomas M. Jessell,Helena Edlund	92
16	Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas 1997 ·Current Biology ·Åsa Apelqvist,Ulf Ahlgren,Helena Edlund	331
17	Sonic hedgehog: a common signal for ventral patterning along the rostrocaudal axis of the neural tube 1995 ·The International Journal of Developmental Biology ·Johan Ericson,Jonas Muhr,Thomas M. Jessell,Helena Edlund	115
18	Islet expression of Rhombotin and Isl-1 suggests cell type specific exposure of LIM-domain epitopes 1995 ·Endocrine ·Kaare Lund,Jacob Petersen,Jan Jensen,Niels Blume,Helena Edlund,Stefan Thor,Ole Madsen	4
19	Individual Protein-Binding Domains of the Insulin Gene Enhancer Positively Activate β-Cell-Specific Transcription 1989 ·Molecular and Cellular Biology ·Olof Karlsson,Michael Walker,William J. Rutter,Helena Edlund	23
20	Differential Expression of Interferon Genes in a Substrain of Namalwa Cells 1985 ·Journal of Interferon Research ·B Lund,Alexander von Gabain,Helena Edlund,Tor Ny,Erik Lundgren	15

About Helena Edlund

Helena Edlund is a scholar working on Developmental Neuroscience, Genetics and Surgery, having authored 135 papers that have together received 24.0k indexed citations. Recurring topics across this work include Pancreatic function and diabetes (66 papers), Congenital heart defects research (23 papers) and Developmental Biology and Gene Regulation (23 papers). The work is most often cited by research in Developmental Neuroscience (2.1k citations), Genetics (8.0k citations) and Endocrinology, Diabetes and Metabolism (4.2k citations). Helena Edlund has collaborated with scholars based in Sweden, United States and United Kingdom. Frequent co-authors include Thomas M. Jessell, Jörgen Jönsson, Lena Carlsson, Ulf Ahlgren, Helena Ohlsson, Samuel L. Pfaff, Michael Walker, Stefan Thor, William J. Rutter and Johan Ericson. Their work appears in journals such as Nature, Science and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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