Harry Ischiropoulos

51.2k total citations · 21 hit papers
214 papers, 37.8k citations indexed

About

Harry Ischiropoulos is a scholar working on Physiology, Molecular Biology and Neurology. According to data from OpenAlex, Harry Ischiropoulos has authored 214 papers receiving a total of 37.8k indexed citations (citations by other indexed papers that have themselves been cited), including 115 papers in Physiology, 63 papers in Molecular Biology and 47 papers in Neurology. Recurrent topics in Harry Ischiropoulos's work include Nitric Oxide and Endothelin Effects (85 papers), Parkinson's Disease Mechanisms and Treatments (42 papers) and Neutrophil, Myeloperoxidase and Oxidative Mechanisms (26 papers). Harry Ischiropoulos is often cited by papers focused on Nitric Oxide and Endothelin Effects (85 papers), Parkinson's Disease Mechanisms and Treatments (42 papers) and Neutrophil, Myeloperoxidase and Oxidative Mechanisms (26 papers). Harry Ischiropoulos collaborates with scholars based in United States, Greece and Uruguay. Harry Ischiropoulos's co-authors include Joseph S. Beckman, Stephen C. Bondy, Carl LeBel, Csaba Szabó, Rafael Radí, Benoit I. Giasson, Ling Zhu, Virginia M.‐Y. Lee, James A. Royall and Serge Przedborski and has published in prestigious journals such as Science, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Harry Ischiropoulos

213 papers receiving 37.1k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Evaluation of the probe 2',7'-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress

1992 2.4k citations Harry Ischiropoulos et al. profile →
Peroxynitrite: biochemistry, pathophysiology and development of therapeutics

2007 1.8k citations Csaba Szabó, Harry Ischiropoulos et al. profile →
Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations

2011 1.4k citations Harry Ischiropoulos et al. profile →
Oxidative Damage Linked to Neurodegeneration by Selective α-Synuclein Nitration in Synucleinopathy Lesions

2000 1.3k citations Benoit I. Giasson, Harry Ischiropoulos et al. profile →
Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase

1992 1.3k citations Harry Ischiropoulos, Jun Chen et al. profile →
Peroxynitrite, a cloaked oxidant formed by nitric oxide and superoxide

1992 1.1k citations Harry Ischiropoulos, Joseph S. Beckman et al. profile →
Evaluation of 2′,7′-Dichlorofluorescin and Dihydrorhodamine 123 as Fluorescent Probes for Intracellular H2O2 in Cultured Endothelial Cells

1993 1.0k citations Harry Ischiropoulos et al. profile →
Blockade of Microglial Activation Is Neuroprotective in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Mouse Model of Parkinson Disease

2002 1.0k citations Harry Ischiropoulos, Serge Przedborski et al. Journal of Neuroscience profile →
Peroxynitrite formation from macrophage-derived nitric oxide

1992 980 citations Harry Ischiropoulos, Joseph S. Beckman et al. profile →
Biological Tyrosine Nitration: A Pathophysiological Function of Nitric Oxide and Reactive Oxygen Species

1998 898 citations Harry Ischiropoulos profile →
[23] Oxidative chemistry of peroxynitrite

1994 872 citations Joseph S. Beckman, Jun Chen et al. Methods in enzymology on CD-ROM/Methods in enzymology profile →
Peroxynitrite-mediated oxidation of dihydrorhodamine 123

1994 645 citations Harry Ischiropoulos et al. profile →
Kinetics of superoxide dismutase- and iron-catalyzed nitration of phenolics by peroxynitrite

1992 635 citations Joseph S. Beckman, Harry Ischiropoulos et al. profile →
Apolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease

2004 577 citations Lemin Zheng, Mingjiang Sun et al. Journal of Clinical Investigation profile →
Oxidative stress and nitration in neurodegeneration: Cause, effect, or association?

2003 569 citations Harry Ischiropoulos, Joseph S. Beckman Journal of Clinical Investigation profile →
Apolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease

2004 563 citations Lemin Zheng, Marie‐Luise Brennan et al. Journal of Clinical Investigation profile →
Oxidative stress and nitration in neurodegeneration: Cause, effect, or association?

2003 552 citations Harry Ischiropoulos, Joseph S. Beckman Journal of Clinical Investigation profile →
Peroxynitrite‐mediated oxidative protein modifications

1995 529 citations Harry Ischiropoulos et al. FEBS Letters profile →
Dopamine-modified α-synuclein blocks chaperone-mediated autophagy

2008 516 citations Marta Martínez‐Vicente, Zsolt Tallóczy et al. Journal of Clinical Investigation profile →
NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease

2003 510 citations Harry Ischiropoulos, Serge Przedborski et al. profile →
T2R38 taste receptor polymorphisms underlie susceptibility to upper respiratory infection

2012 433 citations Paschalis‐Thomas Doulias, Harry Ischiropoulos et al. Journal of Clinical Investigation profile →

Peers

Countries citing papers authored by Harry Ischiropoulos

Since Specialization

Citations

This map shows the geographic impact of Harry Ischiropoulos's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Harry Ischiropoulos with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Harry Ischiropoulos more than expected).

Fields of papers citing papers by Harry Ischiropoulos

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Harry Ischiropoulos. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Harry Ischiropoulos. The network helps show where Harry Ischiropoulos may publish in the future.

Co-authorship network of co-authors of Harry Ischiropoulos

This figure shows the co-authorship network connecting the top 25 collaborators of Harry Ischiropoulos. A scholar is included among the top collaborators of Harry Ischiropoulos based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Harry Ischiropoulos. Harry Ischiropoulos is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Protein tyrosine nitration 2024 ·SHILAP Revista de lepidopterología ·Harry Ischiropoulos	3
2	Nitrative Modification of Caveolin-3: A Novel Mechanism of Cardiac Insulin Resistance and a Potential Therapeutic Target Against Ischemic Heart Failure in Prediabetic Animals 2023 ·Circulation ·Zhijun Meng, Zhen Zhang, Jianli Zhao, Caihong Liu, Peng Yao, Ling Zhang, Dina Xie, Wayne Bond Lau, (unknown), Theodore A. Christopher, Bernard S. López, Di Zhu, Demin Liu, (unknown), Erhe Gao, Harry Ischiropoulos, Walter J. Koch, Xinliang Ma, Yajing Wang	18
3	ASS1 and ASL suppress growth in clear cell renal cell carcinoma via altered nitrogen metabolism 2021 ·SHILAP Revista de lepidopterología ·Sanika Khare, Laura C. Kim, (unknown), Paschalis‐Thomas Doulias, Harry Ischiropoulos, Itzhak Nissim, Brian Keith, M. Celeste Simon	20
4	Nitric Oxide Disrupts Zinc Homeostasis in Salmonella enterica Serovar Typhimurium 2018 ·mBio ·Elaine R. Frawley, Joyce E. Karlinsey, Anshika Singhal, Stephen J. Libby, Paschalis‐Thomas Doulias, Harry Ischiropoulos, Ferric C. Fang	26
5	S-Nitrosylation of Calcium-Handling Proteins in Cardiac Adrenergic Signaling and Hypertrophy 2015 ·Circulation Research ·Tomoya Irie, Patrick Sips, Shinichi Kai, Kotaro Kida, Kohei Ikeda, Shuichi Hirai, Kasra Moazzami, Pawina Jiramongkolchai, Donald B. Bloch, Paschalis‐Thomas Doulias, Antonis A. Armoundas, Masao Kaneki, Harry Ischiropoulos, Evangelia G. Kranias, Kenneth D. Bloch, Jonathan S. Stamler, Fumito Ichinose	58
6	Protein Microarray Characterization of the S-Nitrosoproteome 2013 ·Molecular & Cellular Proteomics ·Yun-Il Lee, (unknown), Ho Chul Kang, Yunjong Lee, Jun Seop Jeong, Paschalis‐Thomas Doulias, Zhi Xie, Jianfei Hu, Mehdi Ghasemi, Harry Ischiropoulos, Jiang Qian, Heng Zhu, Seth Blackshaw, Valina L. Dawson, Ted M. Dawson	50
7	Co-compartmentalization of the Astroglial Glutamate Transporter, GLT-1, with Glycolytic Enzymes and Mitochondria 2011 ·Journal of Neuroscience ·(unknown), Joshua G. Jackson, Amanda L. Sheldon, (unknown), Todd M. Greco, John C. O’Donnell, Lynn A. Spruce, Rui Xiao, Wensheng Guo, Mary Putt, Steven H. Seeholzer, Harry Ischiropoulos, Michael B. Robinson	162
8	Dopamine-modified α-synuclein blocks chaperone-mediated autophagy breakdown → 2008 ·Journal of Clinical Investigation ·Marta Martínez‐Vicente, Zsolt Tallóczy, Susmita Kaushik, Ashish C. Massey, Joseph R. Mazzulli, Eugene V. Mosharov, Roberto Hodara, Ross A. Fredenburg, (unknown), Antonia Follenzi, William T. Dauer, Serge Przedborski, Harry Ischiropoulos, Peter T. Lansbury, David Sulzer, Ana María Cuervo	516
9	Cytosolic Catechols Inhibit α-Synuclein Aggregation and Facilitate the Formation of Intracellular Soluble Oligomeric Intermediates 2006 ·Journal of Neuroscience ·Joseph R. Mazzulli, (unknown), Benoit I. Giasson, David R. Lynch, Steven Thomas, Akira Nakashima, Toshiharu Nagatsu, Akira Ota, Harry Ischiropoulos	129
10	Apolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease breakdown → 2004 ·Journal of Clinical Investigation ·Lemin Zheng, (unknown), Marie‐Luise Brennan, Mingjiang Sun, Marlene Goormastic, Megan Settle, (unknown), Xiaoming Fu, Leonor Thomson, Paul L. Fox, Harry Ischiropoulos, Jonathan D. Smith, Michael Kinter, Stanley L. Hazen	563
11	Immunohistochemical Detection of <I>S</I>-Nitrosylated Proteins 2004 ·Humana Press eBooks ·Andrew J. Gow, Christiana Davis, David Munson, Harry Ischiropoulos	17
12	Oxidative stress and nitration in neurodegeneration: Cause, effect, or association? breakdown → 2003 ·Journal of Clinical Investigation ·Harry Ischiropoulos, Joseph S. Beckman	552
13	Oxidative stress and nitration in neurodegeneration: Cause, effect, or association? breakdown → 2003 ·Journal of Clinical Investigation ·Harry Ischiropoulos, Joseph S. Beckman	569
14	Oxidative Modifications of α‐Synuclein 2003 ·Annals of the New York Academy of Sciences ·Harry Ischiropoulos	71
15	Vascular Immunotargeting of Glucose Oxidase to the Endothelial Antigens Induces Distinct Forms of Oxidant Acute Lung Injury 2002 ·American Journal Of Pathology ·Melpo Christofidou‐Solomidou, Stephen J. Kennel, Arnaud Scherpereel, Rainer Wiewrodt, Charalambos Solomides, Giuseppe G. Pietra, Juan-Carlos Murciano, Sayed Afzal Shah, Harry Ischiropoulos, Steven Μ. Albelda, Vladimir R. Muzykantov	46
16	Mercaptoethylguanidine, an inhibitor of nitric oxide synthase, and a scavenger of peroxynitrite exerts beneficial effects in hemorrhagic shock 1997 ·The FASEB Journal ·Basilia Zingarelli, Harry Ischiropoulos, Andrew L. Salzman, Csaba Szabó	2
17	[17] Detection and quantitation of nitrotyrosine residues in proteins: In vivo marker of peroxynitrite 1996 ·Methods in enzymology on CD-ROM/Methods in enzymology ·John P. Crow, Harry Ischiropoulos	166
18	Endotoxin triggers the expression of an inducible isoform of nitric oxide synthase and the formation of peroxynitrite in the rat aorta in vivo 1995 ·FEBS Letters ·Csaba Szabó, Andrew L. Salzman, Harry Ischiropoulos	202
19	Role of Neutrophils and Nitric Oxide in Lung Alveolar Injury from Smoke Inhalation 1994 ·American Journal of Respiratory and Critical Care Medicine ·Harry Ischiropoulos, (unknown), D. L. Fisher, Aron B. Fisher, Stephen R. Thom	43
20	[23] Oxidative chemistry of peroxynitrite breakdown → 1994 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Joseph S. Beckman, Jun Chen, Harry Ischiropoulos, John P. Crow	872

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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